Basic Information

Insect: Drosophila helvetica
Gene Symbol: ham
Assembly: GCA_963969585.1
Location: OZ018402.1:3878167-3900415[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.057 5.5 8.1 0.0 2 21 352 371 351 374 0.87

2 9 0.0012 0.11 13.4 0.9 1 23 381 404 381 404 0.93

3 9 1.7e-07 1.6e-05 25.5 1.7 1 23 410 433 410 433 0.96

4 9 1e-06 0.0001 23.0 1.6 1 23 439 461 439 461 0.97

5 9 8e-05 0.0077 17.1 3.8 1 23 467 489 467 489 0.97

6 9 0.002 0.19 12.7 1.7 2 21 497 516 496 517 0.94

7 9 6.2e-09 5.9e-07 30.0 1.3 1 23 960 982 960 982 0.99

8 9 5e-07 4.8e-05 24.0 0.9 1 23 988 1011 988 1011 0.97

9 9 2.9e-05 0.0028 18.4 3.4 1 23 1017 1039 1017 1039 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.057	5.5	8.1	0.0	2	21	352	371	351	374	0.87
2	9	0.0012	0.11	13.4	0.9	1	23	381	404	381	404	0.93
3	9	1.7e-07	1.6e-05	25.5	1.7	1	23	410	433	410	433	0.96
4	9	1e-06	0.0001	23.0	1.6	1	23	439	461	439	461	0.97
5	9	8e-05	0.0077	17.1	3.8	1	23	467	489	467	489	0.97
6	9	0.002	0.19	12.7	1.7	2	21	497	516	496	517	0.94
7	9	6.2e-09	5.9e-07	30.0	1.3	1	23	960	982	960	982	0.99
8	9	5e-07	4.8e-05	24.0	0.9	1	23	988	1011	988	1011	0.97
9	9	2.9e-05	0.0028	18.4	3.4	1	23	1017	1039	1017	1039	0.98

Sequence Information

Coding Sequence: ATGCTGTTCGATCGATATGTCATATCAGGCTCTAACGGCGACGACTACGATCCGAGTGTTGtgcgccaccaccaccaccatcatcaccatcacctGGATCTCAGCACGCGGGCTCCGGCCTTCGGTCCCCTGCCGGATCACACGCAGCTTCCCGCAGAGGACTCCTCCGCATTCGCCAATCGCCACCACCTGCCACAGACTCCTGCCACATCCTCGGCAGCCGCCTCGCCGCCCCTGGAGCCGCAGCAGCACCTGCAGCACCACCCCCAAGATCAGcatctgcagcaccagcaccagcaccaccagcaccagcaccagcttcaacagcagcggcaacagccaCCGCCTCCCACGTTGCCGCTGGCTGGCTCCTCAGCAGCCTCCAGCATGGAGCACTTCTTCAACGACCAGGCCCAGGCGGAGCAGCTCCTCCAGGAGTGGGCCCGCCGGCGCGAACCTGTCTGTGATCTGGATATCCGTGATAGTGGCGTCTACGCCAAGACGCATCTGCAGCGTGGCACTCGCTACGGGCCCTTCCCCGTGAAACTCTGCCATCAGCCCAACGATCCTCAACTGGCATGGAAGGCCCATGCTGGACCCAACTTTAATGGCTGGCTCGAGCCCACATCGGACGTGTCGACGTGGCTGAAGAAAATCCGCTCCGTGAAGGACATCGAGTGCATCGAAGAGGCTAATTTACACAATTACATAATGGGCGGCTGTTTGTGGTACGAAACGAATCGGTATATCAATGCAGGCAGTGAAATGGTCGTGGATGGCCGTCCCAAGACCCCGTACCAGATCAATGACAACTTTATGGCCGGCGGCGGGGTCctggcggcagcagcagccgccgcagcagccgcagccgcggCAGCAGTCGCCTCGGGAGCCACCAGTGGCGGGGGAAGTTCATTACCCAGCGACGATCGGAGCGATCGAGATAATGGTTCCCTTTACAGCGGTGACGAATTCTCCAAAGACAAGAAAAACTCATCGCTAATCAGTCAAGGCGATATTGATTTCACAGACGACGAAAACGGTTTCGACATACGCTGTGAGGTCTGTGATAAAGTCTATCCGGATTTAGAACGCTTGGACGATCATCTGGTGGGCGCCCATCATTTCAAGCAGGACGAGTTCCCATGCAAACTGTGTTCGCAGCGCTTCAGCCATCGTCCTTTGTTGATCAAACACGAGGCTATATCCCACAATAATATACGGAAATATTCCTGCGAGAATTGTAGCAAGGTATTTTGTGACCCATCGAATCTACAGCGCCATATTCGCGCCTACCACGTCGGCGCTCGCTGTCATCCGTGTCCGGAGTGCGGCAAGACATTTGGGACCTCGTCGGGGCTgaagcagcaccagcacatCCACTCCTCGGTGAAGCCCTTCGCCTGCGAGGTGTGCTTCAAGGCGTACACGCAGTTCTCGAATCTGTGCCGACACAAGCGGATGCACGCCACCTGCCGCATGCAGATCAAGTGCTCCAAGTGCAACCAGAGCTTCAGTACCGTCACCTCGCTCTCGAAGCACAAGAAGTTCTGCGACTCCACGGGCTCGTACCGCAACCAGCCGTTGGGGCgccatcagcatcagcatcagcatccgTTAGCCGCCACCTCGACATCCAGTCAGCCCCAGCCAGGAGGCGACTCTCAGGGagaatcatcatcatctgctgctgctgcggctgctgctgccgctgccgccatGACGACGCCACCAAATCCCTTCCTCATGTTCCGCCCAGGACCTCCGTTCTTCCCAGGATTTCCGCCGTACGGTCTGCCTGGGATCTTTCCCTCCAGTCCCCTGAGGGCCGCCAACTTCCCCCTCTTCTTTCCGAAGCCCCCGATGGACCTGGGCTGTGGCATGCCGTCCATGACCTCGCCCAATGCCGCCTACCGCCATCATCCCTTCGCTCTGGATCTGGAGAGACAGCAGGGTGGACAGTCGCCCCTTCAGGAGCACCATCAGGCGAAGGCGGAGCGAGGCTCCACGCCCGATGAGAAGAAGCTCAAGTCGGAGCCACTCCTGCAGGTCTCCgaagaggacgaggaggaCGATCTCCAGTCCAGGGACATGAAGATGGAGCCAGAGGAGGAGTCCCAAAAGGATCTCAAGTCTGAGGAGCGGAAGGAGCTCAAGAGGGAGAGCTCTCCCGATCAGCAGCAGGCTGAAGATGACAGGAAATCCATCGACATCGTGAGCACGCCACCGCCCACGGACTCGACGTGCGAGAAACCCACCTCGGAGCTGCCTCTCGATCTGTCCATTTGCCGCAAGCGATTCCCCTCCTACCGCAGTCGTACGCCGTCGCCTTCGCCGCTCATGTTTCTGCCCGACGAGGATGTGGACGCAGAGCCTCCGATGAAGCAGAGCCGCAAGAGCCACAGCTCGGGGGAGTCGTCCACGTCGCGGCAGTCCTACAAGGGCAGCAGTCCCACGCCCAGTGCCTCGCCAGGACCCACACCATCGCCGTCCCCGCCCACAAGTGCCGGGGGGGAGATGAGCAGCATGTCGGAGGGAGCTGTGGCAGCGGCACAAGCCGCAGCAGTGGCCGCTGGGGCGGCCGAGGCTGCCACGGCGGCGGCCATGGCCTGTCCACGGCCCCTgcatccgctgctgctggaggagaTCTACCGATCCCGGGCCCTGGCCGGACTCTCACAGCGCACGTTTCCTTTTTTATGCCCAACGGGCGGACGGCCAAATATTGAGGCGATGCtgacagcaggagcagccaaCGGCAAGGGCTGCTCGACACCCTCGACCAGGCCGCTTCCGCCCGTGAACTTCCGCGAGGCGTTGCGCTACGCcaccagtgccagtgcccgcTCTCCGAGCGCCCTCAAGACCAAGGATCGCTACACCTGCAAGTTCTGCGGCAAGGTGTTCCCCCGATCCGCGAACCTCACGCGCCACCTGCGCACCCACACGGGCGAGCAGCCGTACTCCTGCAAGTACTGCGACCGTGCCTTCAGCATATCCTCGAACCTGCAGCGCCACGTCCGGAACATCCACAACAAGGAGCGCCCCTTCCGCTGCGAGCTGTGCGACCGCTGCTTCGGCCAGCAAACGAATCTCGATCGCCATGTGAAGAAGCACGAGGCGGATGCCAACGGCACCGGCGGGGGCTTCGGCGACTTCCGGGACTCGCCCAGTTCCGCGGAGGCCGAGCGGGATGAGTACTTCGACGAGATCCGCACCTTCATGAATCGCGTGTACACGCCCAACAGCTTGGGCGGGGCCGATGGCGACACGGAGGAGTACGCGGGCAGCGATGATCAGTTGTCCGTGTCCACCCGTCAGTCCGTCAATCTGGACAAGGACACCAGCAACAATAataccagcaacagcaacaacaacaacaataacaacaacaagagcagcagcagcacgaatGGAGGAAAGGCCATTGCAGTGAGCACTTGA
Protein Sequence: MLFDRYVISGSNGDDYDPSVVRHHHHHHHHHLDLSTRAPAFGPLPDHTQLPAEDSSAFANRHHLPQTPATSSAAASPPLEPQQHLQHHPQDQHLQHQHQHHQHQHQLQQQRQQPPPPTLPLAGSSAASSMEHFFNDQAQAEQLLQEWARRREPVCDLDIRDSGVYAKTHLQRGTRYGPFPVKLCHQPNDPQLAWKAHAGPNFNGWLEPTSDVSTWLKKIRSVKDIECIEEANLHNYIMGGCLWYETNRYINAGSEMVVDGRPKTPYQINDNFMAGGGVLAAAAAAAAAAAAAAVASGATSGGGSSLPSDDRSDRDNGSLYSGDEFSKDKKNSSLISQGDIDFTDDENGFDIRCEVCDKVYPDLERLDDHLVGAHHFKQDEFPCKLCSQRFSHRPLLIKHEAISHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARCHPCPECGKTFGTSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHATCRMQIKCSKCNQSFSTVTSLSKHKKFCDSTGSYRNQPLGRHQHQHQHPLAATSTSSQPQPGGDSQGESSSSAAAAAAAAAAAMTTPPNPFLMFRPGPPFFPGFPPYGLPGIFPSSPLRAANFPLFFPKPPMDLGCGMPSMTSPNAAYRHHPFALDLERQQGGQSPLQEHHQAKAERGSTPDEKKLKSEPLLQVSEEDEEDDLQSRDMKMEPEEESQKDLKSEERKELKRESSPDQQQAEDDRKSIDIVSTPPPTDSTCEKPTSELPLDLSICRKRFPSYRSRTPSPSPLMFLPDEDVDAEPPMKQSRKSHSSGESSTSRQSYKGSSPTPSASPGPTPSPSPPTSAGGEMSSMSEGAVAAAQAAAVAAGAAEAATAAAMACPRPLHPLLLEEIYRSRALAGLSQRTFPFLCPTGGRPNIEAMLTAGAANGKGCSTPSTRPLPPVNFREALRYATSASARSPSALKTKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYSCKYCDRAFSISSNLQRHVRNIHNKERPFRCELCDRCFGQQTNLDRHVKKHEADANGTGGGFGDFRDSPSSAEAERDEYFDEIRTFMNRVYTPNSLGGADGDTEEYAGSDDQLSVSTRQSVNLDKDTSNNNTSNSNNNNNNNNKSSSSTNGGKAIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00564084;
90% Identity: iTF_00564084;
80% Identity: -