Basic Information

Insect: Drosophila hawaiiensis
Gene Symbol: ken1
Assembly: GCA_037043685.1
Location: JBAMBA010000022.1:789444-791835[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.065 4.3 7.9 5.9 3 23 253 273 251 273 0.96

2 11 0.00063 0.042 14.3 0.5 1 23 279 304 279 304 0.94

3 11 1.1 75 4.0 0.2 8 23 333 348 332 348 0.89

4 11 0.0018 0.12 12.8 2.2 1 23 355 377 355 377 0.97

5 11 0.007 0.46 11.0 0.5 1 23 383 405 383 405 0.97

6 11 0.051 3.4 8.3 2.6 1 23 411 434 411 434 0.97

7 11 0.018 1.2 9.7 4.1 1 23 440 462 440 462 0.95

8 11 0.009 0.59 10.6 2.3 2 23 469 490 468 490 0.96

9 11 0.00018 0.012 16.0 0.8 1 23 579 602 579 602 0.95

10 11 0.00036 0.024 15.0 0.8 1 23 608 630 608 630 0.95

11 11 9.6e-06 0.00063 20.0 2.3 1 23 636 658 636 658 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.065	4.3	7.9	5.9	3	23	253	273	251	273	0.96
2	11	0.00063	0.042	14.3	0.5	1	23	279	304	279	304	0.94
3	11	1.1	75	4.0	0.2	8	23	333	348	332	348	0.89
4	11	0.0018	0.12	12.8	2.2	1	23	355	377	355	377	0.97
5	11	0.007	0.46	11.0	0.5	1	23	383	405	383	405	0.97
6	11	0.051	3.4	8.3	2.6	1	23	411	434	411	434	0.97
7	11	0.018	1.2	9.7	4.1	1	23	440	462	440	462	0.95
8	11	0.009	0.59	10.6	2.3	2	23	469	490	468	490	0.96
9	11	0.00018	0.012	16.0	0.8	1	23	579	602	579	602	0.95
10	11	0.00036	0.024	15.0	0.8	1	23	608	630	608	630	0.95
11	11	9.6e-06	0.00063	20.0	2.3	1	23	636	658	636	658	0.98

Sequence Information

Coding Sequence: atgaatgaggGGAGTGAATACTCCATTCACTCAATATGCCGAATCTGCTTAAATCACCTGCGAAATGATCCGGCGTACGACCTGTTTCTCGTTCCGGGTCTGGCCaaaaaactgtgtgtgtgtacttcaCTCTCAGTGGAACAGCACGATGGCTTCCCGAAAAACCTTTGCACCAATTGCTACACCAAGCTGAACGACTTGCACGGGTTCCAAAAGTTGTGCGTGGACTCTGTACAAAAGTTTCAGGAAATGGTCGCTAGCAATTATTTTACACCTGTTATTGCCgatattaatcaaattgacAATGTCGACATACTGCACGTTCCAGCGCACGATGGAGATATGGAAGAGGATCGCATAAACTTTGATCCGCTGCTAAATACGAAAATTGAGATAATTGAGAATGAAGAGGAGGTTTTCAAAATGCTGGAAGATGTCGACAAAGAAGCGGAGGAGGTAGAAAAAGAGAAGGAGTCATCTAGTGATACTGAACACgataacgatgatgatgttgactTTGAAGCGAATAGTAGTGAATCTGACGACGCCATGCCCCTGTCGCGTTTACGAAGCACTACCAGAGCATCAAAGACAAAGGCTAAAAAGAGCACTCCGGATGATTTTGACGATGACTCTTCCAGCTCTGATTCggatgacgatgacaatgatgatgatgatgacgacgataaGCCCagaacaaaaccaaaacgcaAACGCATTCCGGCTGCTGAGAGACACTTGCATCGCCTCATCGATTGTCACATTTGCCACCAGAAATTCAAGAAGGCAATTCGCTACGAGGAGCACATGAAGCATCACAACGATCTATTGCCATTCCAGTGCACTGTGGAAACCTGCAGGAAGGGTTTCACTACGGCTGGGGGTCTGCGCCTTCATATGGATCACGCCCATTCAGAATTCTCTGAAGTGCACGCCTGCACGTGCACAAAGTGGCCAAGGCTGACACCCGTAATCATCCGTGCACGGAATGCGAAAAAAGTCTTCCGTTGTCCAACGGCGCTTAAGAAACACATGTATAAGCACACTGGCGAGGAGCTGCCTTTTGCATGCGAGATCTGTGGCAAACGGTTCCACATCCATAGTGTGCTTAGAGACCATCTCTTGCGCCATGCCGGTGTAAAGAATCATGTGTGCCCCTACTGCGGCGTCGGTAAAACCACTCGCCAGGAGTGGAACAAACACATTCTGACCCACACCAAGGAAAAACAGTTCCAGTGTCGCCAGTGCGATCATGCTTCCCACAACAAACAGGCTTTGTCCAATCACGTCAAGGTGGTGCACATGAAGATCAAAAACTTTGCGTGTCAGTATTGTGGCAAGACCTTTGGCAAATCGCATGCATGCAAGATCCATGAGAGACTTCACACGGGCGAAAACTGCTGCGAGTGCAAGATCTGTGGCAAGATCTTCCTTTTCGAGAAAAGATTAACCAAGCATTTGCAGATCCATGAGAAACGTGAAACAGCTCCGCCTGCAACCGTTGTTAAGCCGCAAGAGGAAGGAGATGCTCAAAACACGCAGAATGTGAACCAGGACTTGACTGAGCCAGTGGATGTTAAGCCCGTGCCAATAATTCCTCCTAAACCGAAAAATTCGCATCGAGTTGAGCGTGTTGATATATCGCAGCTAGCAGGCACTTCTGTCAATCCAATATCATCAGTATCGGTGCCATCCTGGGCGCCACAAGTGAACTTCACAAAGAAGGAAGGCCAGCATATTTGTCCAGGATGTGGTCGTGGCTTCAACCATATCGGCAATATGAAACTTCACTACAAGATAATACACGAAAAGGTGAAAGACTTTGCCTGTCGCTATTGTCCAAAGCGCTTCGCCAAAGCGCAGTACCTTCGCAATCATGAATATATCCATACGGGCGAGAAGCCGTTCGAATGTAAGATTTGTGGCAAGCATTTCCGTCAGGAGCAGGTATTGAAGACGCATTTGAAGGTGCATGATAAGCCGCCGAAGCCtcccaaagccaaaaaaccgCCAAAGCCATCTGTTAGCAAAGCAAAGGGATTGAAGGTTGAGCTGAACAAAAAACAGCCAAAGATTTTTGATGAGTTCCAGGATCCCGCTGCGGAACGTGCCGCCGCAACTGCTGCATTGCTGGCACAACAGATGGAGGAGAATGAAGCGAAGCGCAAGGCAGAGGAGGAGACGCGCAAGATTCAAGAGGCTGCATGCGAGCAGCTCAACAGACTTCAAAAGCAGGTGCAGAGTGAGAAGGGCTCCTATGACAGCTACTATGGACAAAAAGCGGAGGCTGATGGTACTAACCTGGATGCTCTCAAATTAGATCATGTGTAA
Protein Sequence: MNEGSEYSIHSICRICLNHLRNDPAYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCTNCYTKLNDLHGFQKLCVDSVQKFQEMVASNYFTPVIADINQIDNVDILHVPAHDGDMEEDRINFDPLLNTKIEIIENEEEVFKMLEDVDKEAEEVEKEKESSSDTEHDNDDDVDFEANSSESDDAMPLSRLRSTTRASKTKAKKSTPDDFDDDSSSSDSDDDDNDDDDDDDKPRTKPKRKRIPAAERHLHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVETCRKGFTTAGGLRLHMDHAHSEFSEVHACTCTKWPRLTPVIIRARNAKKVFRCPTALKKHMYKHTGEELPFACEICGKRFHIHSVLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCRQCDHASHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKRETAPPATVVKPQEEGDAQNTQNVNQDLTEPVDVKPVPIIPPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWAPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRYCPKRFAKAQYLRNHEYIHTGEKPFECKICGKHFRQEQVLKTHLKVHDKPPKPPKAKKPPKPSVSKAKGLKVELNKKQPKIFDEFQDPAAERAAATAALLAQQMEENEAKRKAEEETRKIQEAACEQLNRLQKQVQSEKGSYDSYYGQKAEADGTNLDALKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610124;
90% Identity: iTF_00508555;
80% Identity: -