Basic Information

Insect: Drosophila hawaiiensis
Gene Symbol: -
Assembly: GCA_037043685.1
Location: JBAMBA010000109.1:460054-463742[-]

Transcription Factor Domain

TF Family: THAP
Domain: THAP domain
PFAM: PF05485
TF Group: Zinc-Coordinating Group
Description: The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 6.6e-09 1.1e-05 26.0 0.2 24 87 2 54 1 54 0.80

2 10 1.3e-14 2.2e-11 44.3 0.1 1 87 77 148 77 148 0.77

3 10 1.5e-06 0.0026 18.4 0.0 1 58 181 234 181 255 0.84

4 10 2.1e-15 3.6e-12 46.8 0.1 1 86 272 344 272 345 0.80

5 10 1.3e-14 2.2e-11 44.3 1.4 1 86 479 551 479 552 0.81

6 10 4.3e-15 7.4e-12 45.8 2.4 1 87 615 686 615 686 0.83

7 10 4.7e-15 8.1e-12 45.7 4.1 1 86 799 869 799 870 0.85

8 10 1.6e-11 2.8e-08 34.3 0.1 1 62 962 1018 962 1027 0.81

9 10 5.7e-11 9.7e-08 32.6 0.3 1 58 1031 1079 1031 1095 0.86

10 10 5.3e-09 9.1e-06 26.3 1.4 18 87 1096 1154 1082 1154 0.76

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	6.6e-09	1.1e-05	26.0	0.2	24	87	2	54	1	54	0.80
2	10	1.3e-14	2.2e-11	44.3	0.1	1	87	77	148	77	148	0.77
3	10	1.5e-06	0.0026	18.4	0.0	1	58	181	234	181	255	0.84
4	10	2.1e-15	3.6e-12	46.8	0.1	1	86	272	344	272	345	0.80
5	10	1.3e-14	2.2e-11	44.3	1.4	1	86	479	551	479	552	0.81
6	10	4.3e-15	7.4e-12	45.8	2.4	1	87	615	686	615	686	0.83
7	10	4.7e-15	8.1e-12	45.7	4.1	1	86	799	869	799	870	0.85
8	10	1.6e-11	2.8e-08	34.3	0.1	1	62	962	1018	962	1027	0.81
9	10	5.7e-11	9.7e-08	32.6	0.3	1	58	1031	1079	1031	1095	0.86
10	10	5.3e-09	9.1e-06	26.3	1.4	18	87	1096	1154	1082	1154	0.76

Sequence Information

Coding Sequence: ATGCCCAAGCGTAACCCACAGATATTGGATTGGTGCCACAATTTGCGACTGGATCAGGCGGCTATGAGCGGCTCGGAACAGCACGTTTGTGAACGCCACTTCGAGGCAAACTGCTTCAATGCGTCTAGAGTGCTGCGTCCAGGAGCACGACCCACACTTCATTTAGGTTATGAGGACCTAGACGATGTGATACCGAATCCGGCGAACTGGGAAGAGGATGTGATCGTATGCTGTGTGCCCCACTGCGAAAGCTCCAAGGATGCGGATGAAGTCCAACTGTTTGGGCTGCCAAAGGTGCGCCAGTTGGCGGACAAGTGGCTGCAAAATGTGCGCCTCGATCCGAGCAAGGAACAACTGGCCGGCCTGAAGATCTGCAGTGTGCACTTTGAGGCGAGCTGCATGGAGAATGGACGACCCACCTATGGTGCAATGCCCACACTCCATCTCGGTCACGATGAGCTCGACAATATACACCCAAGCGTAGAGTCGGTGCCGACGAATCAGAAGCGCTACTGCAATAGAGATGGCGCCAGTCACGATTGCTGCTATCCGCAGTGCGTGGAGCTGCAGAAGAGCTATCTGCGGGTTACCTACGAGCTGCCCCAGGAGCAGGAGCTCCGTCAGCAGTGGCTCTCCTATATGGGCCTGGAAGCGCAGCAGCTCgataagcagcagctgcccaagCTCTGTCCACTCCACCTAATCTTGCTCTACGATCACAGTGCGGATCACTTTTCGGCTCACGCCGCTGAGGAGCTGTTGGACTCCAATTATGAGGCAGCGCGCAGCAGCGTTCGCATACGCGTCGTCAGCTGTGCTGTGCGCGGCTGCAGAACGCTCAAACCACGCGACGGTGGTCGGCTGCATGGTTTGCCCACGCGGCGAGATCTGCTGGAGATGTGGCTGCACAACATGCAGCTGGTGTTTTACGAGCAACAGCGTTATATGTACAAGATTTGCAGCAAGCACTTTGAGTCCACATGCTTCACGGAAACAACCAAGCGGCTGAAGCCGTGGAGCATGCCTACGCTGGAGTTGCCGGAGCGCCAACAGGGCGAGATGCCCGCCTATCAGAATCCCACAGAGTTGGAGTGGCAACACATGAATGAGCTGCAGGTCAGCGAGAAAGTAGTTGAGGCTCAGCCGGAGCCATTACTCAAGCTGGAGCCGTTGCCAAAGAAggagccaccaccaccgcagGTTGTGGAAGATGAAGAGGATTGCGACAATAACTCACAGCAGCCACTGGAAATGCAGGCGCTGGAGGTGCTGCTCGAGGTGGGCCATGTCGAGAAGTGCACCACCTACGAGCAAATGGATACCGAGGCAAATCTCAACTATGCCGAGCAGTTCTCGCACAATCCCCTCAGTCCAGGTCCACCTCAATGCCGTATCCCCGTTGTCCAGAATGGACTCCACTACAGTGCACGCCACTGCAGCGTGCATGGCTGCAATGTCACCTCCAATAAtctgagcagcagcatcaagcTACACAAGTTCCCCGTCTCGCTGGATGCCATGCAAAAGTGGATGCACAACACCCAGGTGCTCGTGGACGTCAAATTCGCTTGGCGTTTTCGCATCTGCAGTCATCATTTCATCGAGGATTGCTTTCACGGCTCGCGCATCAGACGTGGGGCGATGCCTACATTGCGACTGGGCTCACGTCGACCGAAGCATATCTATGATAATGAGTTTAATgcccaactgcaactggaacaGTCCAAAGAAGAGGCCAGGGAGGCTCTCGCTGCCCCGCTGGAGTctcagcaacagttgctttCTGCGAATGTAGGTCTGCGCCTGCCGCGCCCAGCTCCGCCCTGCAAATCCAGCAAATACTGTCAGATCGAGGGCTGCTCCAATCACTTGACCAGCGAGAATGTGACGCTGCACAAGTTCCCCCATTCGTCGGATATGTGCGCCAAGTGGCAGCATAACACTCAGGTGCCCTTCGATCCCGAGTTCCGCTGGCGCTATCGCATCTGCAGCGCACACTTTGAGCCCATCTGTCTAGGCAATGTGCGACTGATGCACGGCAGTGTGCCCACCCTGAATCTGGGGCCACTTGCGCCCAAGAAACTGTTTGACAATGAGTTCTTGCGTCTGGACAAGCCAATGAGCAGTTCGGAGCTGGGTATGACCGtcaaacaagaacaaatgGAGCAATTTGATCAAATGGAGCTGGAAGATGGCAACCAAGAGCAGGATGATTTCAGTCTGCTGGAGCCCGAGCTGCAGTTGCACGAGGATAGCGAGGATGAGCAACAATATGACAATCATTTCAGCCAAAACGATTCCTATAACTGGTCCGATCAGCAGCTGCGTCTGCCCAGCATTAATCAGGAGAAGTGCGCCACCATCTACAATCCGGTCAAGTCCGGCTATGATAAGTGCTCACTGGTCCACTGCCAACGACAGCGTTCCCAGCACGGCGTGCACATCTACAAGTTTCCACGCTCGCGTCAGATACAGCAACGATGGATGCATAATTTGCGCATCCAATACGATGAGCGACGGCCGTGGAAGACAATGATATGCAGTGTCCATTTCGAGCCGCACTGCATCCGTCTGCGCAAATTGCGTCCCTGGGCGGTGCCTACGCTGGAACTGGGGGACAATGTGCCGCTGGAGATCTTTACGAACGAGCAGAGCCAGCAACTGTTTGCTCAGTCCGAAGCAGGCAGCGAGTGTGATGACGTTGAAGTGGATGTTGAGGACACCATACTGGAGGACTTGGATGATGACTATGATGACAATGACGCtgatgtgaatgtgaatgctgATGATCAAATGCGAGCAGCTCCATATGTCAAAAGAGAGCGTCGCTCTCGATTTGATCCTCTGCCACCGGGTCAGCTGCCACCGTGGAAGATTAAATGCTGCTGTTTGCCCTATTGCCGCAGTCCTCGCGGTGATGGCATCAAGCTCTTTCGACTGCCCAACAACATCAGCTCCATACGTAAATGGGAGCAGGCCACAGGCATGCGCTTCTATGAGTCCCAGCGAAACACAAAGCTCATCTGCAGTCGACACTTTGATCCGCAGCTTATAGGCCGCAGGGCCCGAGCTGCCCCTGTGGGACCACGTTGCTGCATGCCCGATTGCTCTGAGGATGTCAATGTCCAGCTGCACAAGTTTCCCAAAgATCCTATGCTGCTGCATCAATGGTGTCAGGCGCTCAATCTACCGGATGTTCAAAGCTACTCCGGCAAATACATCTGTGCAGCACATCTGCCCTCCAATGCGATGAGCTGTCTAATTTGTGGCGTGGATGATGTACAGCTGCCAATGCTGGACTTTCCCCAGAATCGCAATCAACGCACCAAGTGGTGTTATAATCTGAAAATCGAGCCTCTGCCCAAGTGGGACAACTCAAAGCAAATTTGCTGCAAACACTTTGAGAGCTTTTGCTTTATCCAGCCGGGTCAACTTCTGGCGGAGGCATTGCCCACGCTACACTTGGAGCACGGAGATAGCAACATATTCCTAAACGATGAGGCCGTGGATAACAGCAAGTTGTTGCGCATCAAGGACGAGCCCATGGAGAGCGAGGATCTGATGCTGTAA
Protein Sequence: MPKRNPQILDWCHNLRLDQAAMSGSEQHVCERHFEANCFNASRVLRPGARPTLHLGYEDLDDVIPNPANWEEDVIVCCVPHCESSKDADEVQLFGLPKVRQLADKWLQNVRLDPSKEQLAGLKICSVHFEASCMENGRPTYGAMPTLHLGHDELDNIHPSVESVPTNQKRYCNRDGASHDCCYPQCVELQKSYLRVTYELPQEQELRQQWLSYMGLEAQQLDKQQLPKLCPLHLILLYDHSADHFSAHAAEELLDSNYEAARSSVRIRVVSCAVRGCRTLKPRDGGRLHGLPTRRDLLEMWLHNMQLVFYEQQRYMYKICSKHFESTCFTETTKRLKPWSMPTLELPERQQGEMPAYQNPTELEWQHMNELQVSEKVVEAQPEPLLKLEPLPKKEPPPPQVVEDEEDCDNNSQQPLEMQALEVLLEVGHVEKCTTYEQMDTEANLNYAEQFSHNPLSPGPPQCRIPVVQNGLHYSARHCSVHGCNVTSNNLSSSIKLHKFPVSLDAMQKWMHNTQVLVDVKFAWRFRICSHHFIEDCFHGSRIRRGAMPTLRLGSRRPKHIYDNEFNAQLQLEQSKEEAREALAAPLESQQQLLSANVGLRLPRPAPPCKSSKYCQIEGCSNHLTSENVTLHKFPHSSDMCAKWQHNTQVPFDPEFRWRYRICSAHFEPICLGNVRLMHGSVPTLNLGPLAPKKLFDNEFLRLDKPMSSSELGMTVKQEQMEQFDQMELEDGNQEQDDFSLLEPELQLHEDSEDEQQYDNHFSQNDSYNWSDQQLRLPSINQEKCATIYNPVKSGYDKCSLVHCQRQRSQHGVHIYKFPRSRQIQQRWMHNLRIQYDERRPWKTMICSVHFEPHCIRLRKLRPWAVPTLELGDNVPLEIFTNEQSQQLFAQSEAGSECDDVEVDVEDTILEDLDDDYDDNDADVNVNADDQMRAAPYVKRERRSRFDPLPPGQLPPWKIKCCCLPYCRSPRGDGIKLFRLPNNISSIRKWEQATGMRFYESQRNTKLICSRHFDPQLIGRRARAAPVGPRCCMPDCSEDVNVQLHKFPKDPMLLHQWCQALNLPDVQSYSGKYICAAHLPSNAMSCLICGVDDVQLPMLDFPQNRNQRTKWCYNLKIEPLPKWDNSKQICCKHFESFCFIQPGQLLAEALPTLHLEHGDSNIFLNDEAVDNSKLLRIKDEPMESEDLML

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00514210;
90% Identity: iTF_00514210;
80% Identity: -