Dham005454.2
Basic Information
- Insect
- Drosophila hamatofila
- Gene Symbol
- HIVEP2
- Assembly
- GCA_035045345.1
- Location
- JAWNPA010000012.1:29047225-29056128[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.00039 0.029 15.0 0.3 1 23 255 277 255 277 0.98 2 8 0.0016 0.12 13.0 3.6 1 21 283 303 283 307 0.89 3 8 0.013 0.97 10.2 0.1 1 19 946 964 946 967 0.93 4 8 2.9e-06 0.00022 21.7 2.0 1 23 1702 1724 1702 1724 0.99 5 8 3.2e-05 0.0024 18.4 5.3 1 23 1730 1754 1730 1754 0.92 6 8 0.00061 0.045 14.4 3.4 2 23 2234 2255 2234 2255 0.97 7 8 0.00084 0.062 13.9 1.2 1 23 2261 2285 2261 2285 0.91 8 8 0.0027 0.2 12.4 2.7 1 23 2306 2330 2306 2330 0.92
Sequence Information
- Coding Sequence
- ATGACGCtacagcacagcagcaacaccagcagcagcaacaccagcaacaccagcaccaccaccaccaccaacaacaacaacagcaacaacaacattaatatcagcaacagcagcagtagcagcaacacaaacaacaacaacaacaacgatgttgctgcaacaacagcaattgctgACTGGAAAAGCAGCTCGAACAATTTGCGCTATTTGCACAAGAAGTTCAAACGTTTGGCCAGCACCACAGAAACTGAACCACCAGACGAGACAACGCTGCGCACCACGTCGCTGTCGTCAAACAGTTCAGTGTCGCCGCCAACGCAATTGCCGCTGGTTAATGGGCAcgagcacagcaacaacagcaacagcaacaacatcagtcATGAGGCCGAGAGCTAtagcaaaaatgttgctgttgctgttgctggcgtgcCACGCACGCGTACACCtttgagcaacagcagcaacatcaacagtagcagcagcagcagcagcagcaactatgcCAGCAATGCAACATTGTCGCCAGCAACATTtgcacagcatcagcagcagacgcagccaacgacaacagcagcagcagcagcagcagcagcaacagtcacaccagcagcaatatccaagccagcagcaacatttgcagcaactgcaacagctgctgccatgccagcagcaacaactgcaacctCTGccatgccagcagcagcatctgcaacatctgctgccacagcagcaacagtcacgCCAGCAACTGGCCTCAGTCGCTACATCTGCCCGTATTGCAATCTGATTTGTGCCAAGCCCTCGGTCCTCCAGAAGCACATTCGCGCCCACACGAACGAGCGTCCTTATCCCTGCGAGACTTGCGGCATTGCCTTCAAGACGAAGAGCAACTTCTACAAGCATTGCcgctctcgctcgcacgcgGCGCGCATGCGCGGACTGGATGTGCCCGCCCACGAGGCGGACGGACTTTCCGATCAGGATGGCGACGGAGATCTCAGCAATAGCAGCTCCGAGCTGTTGAGTGTGGAAATTCTAAGTCGCGCCGATTCGCCATATGATGATCAGTCGATGGTCTCGCCAACGCCCTCGCCCTCTACGCTGTCGGCGGCGAAGAGCGCGTACCTGCAACAGCCGCCACTGCCGCAGCACATGCAACAGTTGCCGCTGGGCTCGCCTGCTGCTGGCACCTTGCCGCCAGCAACAGTTGAGAATTTGCACTCGGCGACTGCGCAGCATCGACAGTCGATAGACTACAAGCCATACAAGCCAAAATTTCACAATGCAGCGCTCTATGCgccaggcagcagcaaagagcaacagcagcagcagcagcagcagcaacagcagcagcagcaacagcagcaacaacagcagcaacaacagcagcagcagcagcagccacagttgctgccacagcaacagcaacagaagctgCCTCAACCTTTGCTCGTGCATCCCACTCTCTCACCCAGCACGCATCTGAAGCTGAATCTTCACATTAActcgcatcagcagcagctgcagctgcaacaacatccgcagctccagcagcagcagcaacagttgcagcagcagtcattgttgctggcagcagctgctgctgcaggcaaTGCTGTTGCCCTGCCGCCACCTCCATTGCCCACCTACTACTTGGGACAGACGCCATATTACAACCCCACAGCAGCAATGCATCAGCATGCGTTTGCCCTGCATCAGCTGCAATATCAGCAACAttatcagctgcagcagcagcagcagcaacatctacaacaacaacagcagcagcaacactcgCCGCTGCTCAAGGCGCCAACACagacgcaacagcaacagttgctgccacagcaacaacagcagcaacagttgctgccacagcagcagcagcagcagcagcAGCTGCCTCGCTCTAATAGTCAAcaggcaactgcagcagcaacagcagcagcagcacctgccacgcccacacctgTAGGCAATCTGAGCAGCTTTGCCAGCGGCATGCAAGTGaATGTGGAAAAGGTTCAAGAACACATTTCGAAATTGATCTCACAGAACGAAGCCATCGTGGAGaataaggaaatattgctgcaAAAGAAATATCCCAAGCAATTGAATCGTTCGCGCAGCTtcaacaatgccaacaacaacaatagcagcaacaacagcggcagcaacaacagcaacagcagcaacaacaacagcagcagcagcagccagcaactgGGCGATGCAAAAGTAAATCTAGCACAGAGCATAgtacaaaagcagcaacagcagcagcagcagcagcagcagcagcaacagcagcagcaggtgcaattgcagcaacaacaacaacaacaaatgcagcaCATTCAACAATATAGAGTCATTGAGCCAGTGAATGGCTTGCTcaagcgcagcagcaacatcaccaacagcaacaatgcttATGCTAATCTGAAAGCCACGCCTCCACCTGCTGCCTTGAATGTCAAgttgccaccgccgccgccagcaacaatgctgcaattgctgcattATCGCCAGGACCCAGCAATGCCTTTAAACAAGCtcgaccagcagcagcagcagcaacagcaagcgaCGCCCGCGCAGCAGCCCTTGAATCTATCTGCCAAACCAAAGCCGGCAAaggcagcaccaacaacaacaacaactgcagcagcagcaacaacaacagcagccacaccagcaacatcagcaacaccaacaatcgctgccaaagcagcagcagttgccacTGTCGCTGCAAACAATTCGATTATCAAGAATCTGTTGCTCAATGCTCGCGGCCTGGCCGTGCCCATTGGCGAGGGCGACGACGCCGTCTACTCCTGCCCCATCTGCGCCAACGAATTCCGCAGCGCCGACGAGCTGAAGCAGCACAACAGCACCTACTGCCAGGACGCCAGCAGCAGTGCGCCCATCAGCCCCGCCTCCTCGCCCAGCAGCAAGTACTTTCGCTCCAACTCCATCTCCTTCAGCCTGCCGGAGCTCAAGTCGCACATGGCCAACTCGAAGAATCCGTTGTCCTTGGCCAAGCTGGCCTGGTCGCAGCTCAAGACGAAGCCGAGCAGCCTGGTGCTGAGTCGGCTCAGTGCGGCGCAGTCGCCGGCGCGAACGAGCAGCACGGCAACCACAgttgctggcagcagcaggaactatctggcagcaactgttgcaggcAGCAGTGCTAACAGCggcaatgcaacagcaacaattgctagcagcaacagcctgtacaataacaacaacaacaacatcaacaatctAACAGCTACTAGCAACACTCACAATCtgccagcaacagttgctgttagCATCGATGCCAACAATGTTGCCCTCCGCTTCGTGGATGCCCCTTTGCCCTCGCCCGGCCCGCTGCTGGGCAAGACGCCGCTCGTCGACTACGCCGCGCCCCGCAAAGCCGCCGACGCCCAGGTCGTGATCACCAAAATGCACGAGGATCGCCTGGAGAACATCATCAGCGAGAGCTCAGCGAAGCGAGCAAAGCTGAGCAACGAGAGCGCCTTCGTGCTGCCctcggcaacagcaacatcatcagcaacagcaacagcaggaggcgtgcaacagttgctgttcgGGAATACTCAAGAGCTGCCTGGATTCAATACGGGCAAGGAGGAGCGTTTGAGACGCTTCACCTCCTCAGGCGGCTCGATGATTCCCATCTCCGAGTGCCCCGAGCTGGACAAGAGCCCCAAGATGATCCGGACTCCGCTGCTGTCGGGCGGCAGCTTTCAGGAAATGTCGCCCCGACTGAGTGAGTCCAAGTCGAAGCCCGCCTTTCTGCTcaataccagcagcagcagcaacaacaacatcaacagcaacatcatcagcagcagcagcaacaacaactcgcaGCATTTTCAGTTCCCGCCCATCAACTCGATAACCGCCTTCAATCCCCTCACGCTGCCCGCCATGAGCGAGTCGAGCGGCAAAGCGATTCCCTATGTGCCCGGTATTCCGGGTCCGAGCAGCCTCACATTGCTGCcagcaccgccgccgccgcaacagttgctgctgcagcgtccGCCTGCCATTGATGCGCCGCCCTTCAAGAAGTCTCTGTCGCCCTTCGGAGGCGTCCAGAATCTGCCCAGCGAATTCAGTCGGCAGCCGCCGACTCCTGCCCAGCGCAATGCCCTGCAAtggcagagcaacaacagcaacagcaacagcagcagcaacaagctggcagcaactgttgttgttgctggcgatGCTGGTCAGAAGTTCAATTTCCTGCGCATGGCCGACAATgtgaaggagcagcagcagcagcagcagcaggaggtgcGACATTTCATATTCGATCCGCTGCATGTGGAAACACCAGAAaatgaagcaacaacagcagcagctgcagcatcaaCTGCCacggcaacaacatcagctggcacagcaacaactgttgctAATAAGACGAAATTCCTGCGTCCCACGAGTCTCCCACTAAAGCCGGGCACGTTTACGCCCAAGCGCCATCACGGGATCACACCGACTGCAAATACCCTGCCCTTGATCTCGCCCGAGACGCCGCGTCCTTCCAAGTCCTGCGTGCAGCTCTACCTGAACGGCCACGCCTACACGTACCTGGGCCTCAAGTGCAGCACGAAGATGTTCTACTGCACAGTGAACTGTCCGCAGCCGTCGTACGTGGCCGGCATGCACAAGCTGTCGATGTACAGCGTCTGGCAGGTGTGCGAGGAGAACCAGCCGCATCCACTCGGCCTGAAGCCCAAGCAGGTGATGTCGCTCTACGACTCCAGGCAGAAGATGCTCGGCTCGGGCTTCACTGTCGTCCAGGCCGGCGGCAACAGCCACAACTATGCGCTCGTCGGCTCCCAGCAGACgatcagcagctgctccacgGTGAACAACGCCCAGAGCAAGTTCTACCAGCACCAGACGAAGCCGACGCCAGCCATCGGCGCGCTCAGCGAGGCGAATGTGGCGGCCAAGGCCAACGAGGAGGCAGCCAAGAAGCTGGAGCCGGGCCAACTGCTGGTGGGCGGCTATGAGTCCAACGAGGACTACACCTACATACGCggacgtgggcgtggccgctACGTCTGCTCCGAGTGCGGCATTCGCTGCAAGAAGCCCTCCATGCTGAAGAAGCACATTCGCACGCACACCGACGTGCGTCCGTTTACCTGCAGCCACTGCAGCTTCAGCTTCAAGACCAAGGGCAACCTGACCAAGCATATGCAATCAAAGACGCATTTCAAGAAATGCATTGAACTGGGCATCAATCCAGGTCCCATGCCCGCAGATGGTGAATTcttggatgtggatgtggagtTCGATCAGCAATCCTCAACTTCGGCTGGCGGACGCACTTCATCCATGGCCGGCGACTCTGCAGATTCAGATGATTATAGCGATAACGAATCGGAGAGCAGTGACACAGATGAATCCAAGTCCCGCTTGAAGGAGCATGAGGCAGCGCGTGGtctgctctcgctctcgatGACGCCGCCCATACCACAGAGTGTCTCGCCCTATCCGGCGCAGCTGGAGGCCCCAATGTCCGCAGCGAGTCCGGCGAATAGCATTGGCTCGGCGGGCGGCGCCTCCACGCAGCCCAAGCGCCAGGTGTGCTCGTTCACGTCGCCCAAGCCGCCGTTCGACTATCAGAAACAGGAGCAATACTACTCCAACCCTGAGGAGTCGAAGCCCAAGCGTCAAGTGCCCACGGACGAGAGCAGTGCGCCCATGGACTTGACTAAGCCAAGATCaattgccacagcagcagcagcagcagcagcaacggcagcagtaacagcaacatcgacagcagcaacagttgctgccatGGAGCTGCCCAAGTCGCAGGCACAGCAAATGCGCGACGTCATCTTCGGGGCGGGCAACAACGAGTGTGGCTTCATGAAGACCCTGATCTCGGTGTCGGACAAGGTGCGCATCTCGGCCGAGATGGAGGAGCAGGCGAAGCGCGAGAGCGAACGCGAGGATGTTCTTCTCCACACCTATATCAAGGAGCAGGCGCTGCACAATGCCAAACGCAAGCAGAGCTtgtacaacagcagcagcagctacctAATGACCACcacgaccagcagcagcagcagcagcaacaataacacgactaccagcagcagcaacatgcccattgtgagcagcagccagcagaagGTGGGCATGATATATCATGAGGTGCCCAGCATAGAGGTGCATGAGCCGGAGGCAACAGAGCTGGGAGAATCTGAGAAGGAGCACGAACaaatggagcagcagcagccacagcagcaacttgaagagcgacagcagcaggcaacagcaactgttccagctccagctccagctcctgctcctgctgcagccACGCACAATGCCAatttgccagctgctgtgCAGCAGCCAGATGCCATCGACTTCAAGGGCGTgctgagcaacagcaacaacacgaaGCCCATTGTgacaacagctgctgccactgcaacagcaacagctatcgTCAAGGTGCTGGCAACTGAGGAGAGCTACAAGGCGAGCAGCGagccagcaacagttgctggcacagcaacaactgtagccactccaacaacaacaacaacagccagcagcagcagcagcagcagctatggTGGTCGAGTGGTGCCAGCACCGCCGCCGCCCATCGCCAGCGATGCGCGTCCCACGTGCCTGCTGTGCAGCAAGACCTTCCAGCGGCAGCATCAGCTGACGCTGCACATGAACATCCACTACATGGAGCGCAAGTTCAAGTGCGAGCCGTGCAGCATCTCGTTCCGCACGCAGGGCCATCTGCAGAAGCACGAGCGCTCCGAGGCGCACCGCAACAAGGTGATGATGACCTCGACCTTTGGAGTGCCGACCACATCGAATCCGCGTCCGTTCGAGTGCACGGACTGCAAGATAGCCTTTCGCATACACGGCCACCTGGCCAAGCACCTGCGCTCCAAGACGCACGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCATTCGGCACGTATGCGGAGATCGAGCGGGCGGGCATCAGCCTGACGGAGATCGACACGAGCGACTGCGAGAACTCGCTGATCTCGCTCAAGCTGCTGGCCCAGAAGCTGCTCGAGAAGGATCCCAATAAGCTCAGTGGCTACACGACGCCGTCGGGCATGCTGCAGCTGGTGGGCGGCAGCGAGATGCCCGCTGCCAACCAGGACAGCGCCTCGGAGGACGGCTTCAGTGCGGCAAACAGCGCCGCAGCCTCGGCCATTGCCTCGCTGGACAACGACAGCGCCGGCAACACGCCGCAACGGGCCAGCTCCATGTCCGAGGACGAGACGAACGGGCTGACGAATGGACTGAGCCTGAAGCGGCGCCTGCCCGCcagcagcttcagcagcagcaacggcgacGAGAGCGACAATCCGCTGGAGACGAGCGAGAAGCGTGCGCGAAGCAACACGAATGAATTGACGCTGCCCATTGTCGGCAGCAACtga
- Protein Sequence
- MTLQHSSNTSSSNTSNTSTTTTTNNNNSNNNINISNSSSSSNTNNNNNNDVAATTAIADWKSSSNNLRYLHKKFKRLASTTETEPPDETTLRTTSLSSNSSVSPPTQLPLVNGHEHSNNSNSNNISHEAESYSKNVAVAVAGVPRTRTPLSNSSNINSSSSSSSSNYASNATLSPATFAQHQQQTQPTTTAAAAAAAATVTPAAISKPAATFAATATAAAMPAATTATSAMPAAASATSAATAATVTPATGLSRYICPYCNLICAKPSVLQKHIRAHTNERPYPCETCGIAFKTKSNFYKHCRSRSHAARMRGLDVPAHEADGLSDQDGDGDLSNSSSELLSVEILSRADSPYDDQSMVSPTPSPSTLSAAKSAYLQQPPLPQHMQQLPLGSPAAGTLPPATVENLHSATAQHRQSIDYKPYKPKFHNAALYAPGSSKEQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQLLPQQQQQKLPQPLLVHPTLSPSTHLKLNLHINSHQQQLQLQQHPQLQQQQQQLQQQSLLLAAAAAAGNAVALPPPPLPTYYLGQTPYYNPTAAMHQHAFALHQLQYQQHYQLQQQQQQHLQQQQQQQHSPLLKAPTQTQQQQLLPQQQQQQQLLPQQQQQQQQLPRSNSQQATAAATAAAAPATPTPVGNLSSFASGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNNSSNNSGSNNSNSSNNNSSSSSQQLGDAKVNLAQSIVQKQQQQQQQQQQQQQQQQVQLQQQQQQQMQHIQQYRVIEPVNGLLKRSSNITNSNNAYANLKATPPPAALNVKLPPPPPATMLQLLHYRQDPAMPLNKLDQQQQQQQQATPAQQPLNLSAKPKPAKAAPTTTTTAAAATTTAATPATSATPTIAAKAAAVATVAANNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKQHNSTYCQDASSSAPISPASSPSSKYFRSNSISFSLPELKSHMANSKNPLSLAKLAWSQLKTKPSSLVLSRLSAAQSPARTSSTATTVAGSSRNYLAATVAGSSANSGNATATIASSNSLYNNNNNNINNLTATSNTHNLPATVAVSIDANNVALRFVDAPLPSPGPLLGKTPLVDYAAPRKAADAQVVITKMHEDRLENIISESSAKRAKLSNESAFVLPSATATSSATATAGGVQQLLFGNTQELPGFNTGKEERLRRFTSSGGSMIPISECPELDKSPKMIRTPLLSGGSFQEMSPRLSESKSKPAFLLNTSSSSNNNINSNIISSSSNNNSQHFQFPPINSITAFNPLTLPAMSESSGKAIPYVPGIPGPSSLTLLPAPPPPQQLLLQRPPAIDAPPFKKSLSPFGGVQNLPSEFSRQPPTPAQRNALQWQSNNSNSNSSSNKLAATVVVAGDAGQKFNFLRMADNVKEQQQQQQQEVRHFIFDPLHVETPENEATTAAAAASTATATTSAGTATTVANKTKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGLKPKQVMSLYDSRQKMLGSGFTVVQAGGNSHNYALVGSQQTISSCSTVNNAQSKFYQHQTKPTPAIGALSEANVAAKANEEAAKKLEPGQLLVGGYESNEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCSFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVEFDQQSSTSAGGRTSSMAGDSADSDDYSDNESESSDTDESKSRLKEHEAARGLLSLSMTPPIPQSVSPYPAQLEAPMSAASPANSIGSAGGASTQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRQVPTDESSAPMDLTKPRSIATAAAAAAATAAVTATSTAATVAAMELPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEMEEQAKRESEREDVLLHTYIKEQALHNAKRKQSLYNSSSSYLMTTTTSSSSSSNNNTTTSSSNMPIVSSSQQKVGMIYHEVPSIEVHEPEATELGESEKEHEQMEQQQPQQQLEERQQQATATVPAPAPAPAPAAATHNANLPAAVQQPDAIDFKGVLSNSNNTKPIVTTAAATATATAIVKVLATEESYKASSEPATVAGTATTVATPTTTTTASSSSSSSYGGRVVPAPPPPIASDARPTCLLCSKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLVGGSEMPAANQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETNGLTNGLSLKRRLPASSFSSSNGDESDNPLETSEKRARSNTNELTLPIVGSN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00510052;
- 90% Identity
- -
- 80% Identity
- -