Dham011206.1
Basic Information
- Insect
- Drosophila hamatofila
- Gene Symbol
- -
- Assembly
- GCA_035045345.1
- Location
- JAWNPA010000032.1:4719935-4722514[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 8.2e-06 0.00061 20.3 2.6 1 23 96 118 96 118 0.98 2 14 0.03 2.2 9.1 6.6 1 23 124 146 124 146 0.96 3 14 4.4e-05 0.0033 18.0 0.5 1 23 152 174 152 174 0.97 4 14 3.3 2.4e+02 2.7 1.6 2 13 181 192 180 195 0.88 5 14 0.00032 0.023 15.3 0.0 2 23 198 219 197 219 0.97 6 14 3.2e-06 0.00024 21.6 2.1 1 23 225 247 225 247 0.98 7 14 0.058 4.3 8.2 5.1 1 20 253 272 253 274 0.94 8 14 0.15 11 6.9 1.1 1 20 416 435 416 436 0.92 9 14 0.00015 0.011 16.3 0.8 1 23 446 468 446 468 0.98 10 14 0.073 5.4 7.9 5.0 1 23 487 509 487 509 0.98 11 14 0.0032 0.23 12.1 3.6 1 23 517 539 517 539 0.98 12 14 0.00015 0.011 16.3 9.0 1 23 545 567 545 567 0.99 13 14 6.3e-05 0.0046 17.5 1.0 1 23 573 595 573 595 0.98 14 14 5.5e-05 0.0041 17.7 5.0 1 23 601 623 601 623 0.99
Sequence Information
- Coding Sequence
- ATGAGCGGCATAATCGACTTGTCGTGTGTAAAAATTGAACGCGatcaggagctggagcagcagcaagaattCATTGGAGTCTTGGAGGACGCCACTTGTGTTCAGCTTAAAACTGAGCTGCCTTTCACAGAGATGGACATAGGACCTGTTAAAATAGATCCAGATGTGTTGAGAGAAGAGCAAGCACGAAAGGAGCAGGCTACTAAAAATGAGGCTCCGAGGATTCGCAAGAAGAAgagagctgctgcagcagctgcggtCTCTTCTACAGTTGCCAAGGCTCACCATCAGTGCCCGCATTGTCCACGGCATTTCGAGCGCAGCGATGAGCTGGACATCCACAtgttaatacacacacataatctATCCTACAAGTGTTCCTTCTGTCCGTGCAGTTTTTCACACAAATCCATCTACACCACCCATATGTATGGACATACGGGGAAATTTCCACATCCGTGCCCCGACTGTCCGCAGGGATATATGAAGTATGCAGATCTGATGAAGCATCAACGCACGCATATTGTGAAGGACCTTAACAAATGTCCTTTGTGTCCCAAGAACTGCATACATAAGGGCAAGAATTTTCTGCAATGTCCGCAATGCCCGCGCGTCTTTGCCAAAGGCTTCGAACTGGAGATTCATCTGCAGATCCACAGCAACAAGTTGCCCTACAAGTGTCCACATTGTCCGCTCAGCTTCGGCCACAAATCGAATTATATAGCGCACGTTCGCGACCATACGGGCGAATTTCCACATAAATGCCATTATTGCCTGAAAGGATTTATGAAGCGCACTGAGTTGGTTAAACACACATGCGATGGGTGGAACAGCCCAAGCGTGAGCAAGAGGAAAAAAGATAAGGAAGGAGAGGAGCCTGTGGAGCAATGCGAAACTCTGCCAAAAAAGAAGTCAGTTAAGAGTCAAGTTGAAAAAAGAAGCAGTCCAAGAGTCAAAAAGCCTGCAGAGGACTTGCAGGCAACAGAGAGCATACAAAAGACGCGgaaggagaagcagcagcagcagcagcaggagcacgcgcagcagcagaaatcCTTAACAAAAGCCAGTGCCTTAGTGAAcctgaatattaaaaatgatttaaagctGAGCTCTATCAAAACAGAGCCGCAGGAGGAAGAGGAGCAGAGCAAGCCTAAGCAGCAGCCTTTAAATGCTAACTCAAGACTCGAAGCCAGGAAACCTATAAGACAGCTCGTTGTCAGAATTAAGAAGCTGCGCAgccataaatgcaaattatgcaGCAAGGAATTCCTGACATTAAATGAGCTGCAACTGCATGAAAAATGCTGCAGAAGCGAGCAAAAATATCCTTATGAATGCAAGCAATGCTTGAGGAAGTTCGCCCAGTTGTCCAGCCTCACGGAGCACAAACTCGTTCATACAGTGACACTTCCAGATAAATCCCCGCCTTCTATACGCCCACTTAAACGGCCATTTAAGTGTCCGCACTGCACGTGCACCTTTGGCAGCACCTTGGATCGGAAAAATCATTTGCAAATCCATCAGGCACCGAGCAATTATTCGTACAAGTGTCTGCATTGTGCAAGGACCTATCAGCAGAAGTCACGATTTCTGGTGCACATGCGTGGACATACGGACGAGAGACCCTATCAGTGCACCTACTGCACGAAGTTCTTCAAACACAGCCACGTTCTGAAGAAACATCTGCGCAATCATACGGGCGATCGTCCGTATGAATGTCCGCATTGCTCGAATACCTTTGCAGAGAGCTCGAGCTTCAATGAACATCTACGCGGACATGCTGACGAAGTACCCTACCAGTGTCCACATTGTCCGTGCTTCTTTCGTAAAGCCTATAGCTACAAAGTGCATCTGCGCATCCATACGGGCAAAAAGACGTAA
- Protein Sequence
- MSGIIDLSCVKIERDQELEQQQEFIGVLEDATCVQLKTELPFTEMDIGPVKIDPDVLREEQARKEQATKNEAPRIRKKKRAAAAAAVSSTVAKAHHQCPHCPRHFERSDELDIHMLIHTHNLSYKCSFCPCSFSHKSIYTTHMYGHTGKFPHPCPDCPQGYMKYADLMKHQRTHIVKDLNKCPLCPKNCIHKGKNFLQCPQCPRVFAKGFELEIHLQIHSNKLPYKCPHCPLSFGHKSNYIAHVRDHTGEFPHKCHYCLKGFMKRTELVKHTCDGWNSPSVSKRKKDKEGEEPVEQCETLPKKKSVKSQVEKRSSPRVKKPAEDLQATESIQKTRKEKQQQQQQEHAQQQKSLTKASALVNLNIKNDLKLSSIKTEPQEEEEQSKPKQQPLNANSRLEARKPIRQLVVRIKKLRSHKCKLCSKEFLTLNELQLHEKCCRSEQKYPYECKQCLRKFAQLSSLTEHKLVHTVTLPDKSPPSIRPLKRPFKCPHCTCTFGSTLDRKNHLQIHQAPSNYSYKCLHCARTYQQKSRFLVHMRGHTDERPYQCTYCTKFFKHSHVLKKHLRNHTGDRPYECPHCSNTFAESSSFNEHLRGHADEVPYQCPHCPCFFRKAYSYKVHLRIHTGKKT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -