Basic Information

Insect: Drosophila hamatofila
Gene Symbol: -
Assembly: GCA_035045345.1
Location: JAWNPA010000039.1:18344694-18347610[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0042 0.31 11.7 1.3 2 23 143 165 142 165 0.92

2 12 7.2e-07 5.3e-05 23.6 1.8 2 23 180 202 179 202 0.96

3 12 0.38 28 5.6 8.8 2 23 465 486 465 486 0.97

4 12 1.3e-06 9.3e-05 22.8 2.8 1 23 492 515 492 515 0.96

5 12 0.006 0.44 11.3 0.3 1 23 520 543 520 543 0.96

6 12 6.5e-05 0.0048 17.5 5.5 1 23 561 583 561 583 0.96

7 12 0.00013 0.0097 16.5 1.6 1 23 588 610 588 610 0.98

8 12 3.4e-05 0.0025 18.3 1.7 1 23 616 638 616 638 0.95

9 12 2.4e-05 0.0018 18.8 0.7 1 23 644 666 644 666 0.98

10 12 3.5e-07 2.6e-05 24.6 2.7 3 23 674 694 673 694 0.99

11 12 2.4e-08 1.8e-06 28.3 1.0 1 23 700 722 700 722 0.99

12 12 1.6 1.2e+02 3.6 5.2 1 19 727 745 727 750 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0042	0.31	11.7	1.3	2	23	143	165	142	165	0.92
2	12	7.2e-07	5.3e-05	23.6	1.8	2	23	180	202	179	202	0.96
3	12	0.38	28	5.6	8.8	2	23	465	486	465	486	0.97
4	12	1.3e-06	9.3e-05	22.8	2.8	1	23	492	515	492	515	0.96
5	12	0.006	0.44	11.3	0.3	1	23	520	543	520	543	0.96
6	12	6.5e-05	0.0048	17.5	5.5	1	23	561	583	561	583	0.96
7	12	0.00013	0.0097	16.5	1.6	1	23	588	610	588	610	0.98
8	12	3.4e-05	0.0025	18.3	1.7	1	23	616	638	616	638	0.95
9	12	2.4e-05	0.0018	18.8	0.7	1	23	644	666	644	666	0.98
10	12	3.5e-07	2.6e-05	24.6	2.7	3	23	674	694	673	694	0.99
11	12	2.4e-08	1.8e-06	28.3	1.0	1	23	700	722	700	722	0.99
12	12	1.6	1.2e+02	3.6	5.2	1	19	727	745	727	750	0.88

Sequence Information

Coding Sequence: ATGCCTGACACCTACGGCCAATTCGATGCGGAGCGCGTCTGCCGTGTTTGCTTGCGCGAGGTGGGCGATTTTTACTTCATCTACGATGAGGCGCCCGTGGAGCAGGGCGCGAACATCGCCCAAATACTTAACGAGTGCACGCGCTACACCTGCGAGCGCTATGACAAGATGCCCCATCACATGTGCGACACCTGCATCAAGGCCGCCTGCCAGGCGTATCGCTTCAAGCAGGACGCCGAGAAGGCATACCGTTCGCTTGTGGCTATGCTGGGACGCACACCTGTGACCAAGCCCAACAGCAGCGATGTCTGCACCCAGACTGAGCAATTACCTATGCTGCCGTGCGGGATCTGCAATGATAAATTTCTCAACATTCTCGAATTGCGCCTGCATCGCAGTCGCCAGCACTTGAAGACGGAGGAGCTGAAGTGCAGGCTCTGCGACAAGCAGTTCCAAAAGCTTCGTCAGCTGCGCAACCATCTCGCCGAGCAGCACGATCAAAAGTCAGCGGAGGCGCCTTTGCTACGTCGACGTCTGGAATGTCGAGTTTGTCAACGTGCGTTCTCGCGACGCGATCATCTAATACGCCATATGCGAAAGGCCCACGATGTGCCtcggcagcaggagcaggagtctGCGGCGACCTGGACACCCAATGATGAGGCAACTATGCAAAGCGGCGATGAGCTGGAATCGGCCGCCGTCTTATTCAATGATCCGGCTGCCTGTTCAGACAACGAAAATAACGAGAGTGGCTATCAATGCCATACTACGAATCCAATATCAAGCAATGAGGATTCTGGCGATGATGAAGTGCATGCCGAGGCTAAAGAATCGCTCTGGCTGCACATTAAgccagaaccagaaccagagctggaggcggaggcggaggcggagccAGAAGAGGCGGAAGTCGAGCAAGTGAATCGCGATAGgcgcaaaaagaaaacaagttcAAAGATTGCagctcacacagacacagaggaGGAGCCCGAAGGCGTCAGCAAACTGAAGTCTGCTTCGAGCTCATTTTCAACAGAGGTTAAAGAGGAGCCACTCGCCGCCGGCggcgagcagcagctgtccaTTAAACAGGAGCGACAACGTGCTGACAGCATCAAGGTGGATGAGGAGTATGAGATGGAGGCCGCAACAGCGGACCTGTTCCACAGTGCCGACGAGGATGAAGACGATGACGGGCAGAGCGATCTTGATGAAGAGGACGATgaagatgaggatgaggaggaaGCGAATGTCGAGCTCGATGAGCACAAATCGAAGCTGGCTCAAGTGGAAATCGTGCGAGAGTATTTGCAGAAGCCGACAACGGCTAAGCAGCGACGTCGCCGACGCAAACAGACGCAAAGCGAAACGGAAGCCAATCCGGAGAATCGTTGCGATGTCTGCATGCGCACCTTCTCCCGCCATTGCCATTTGCTGCGACACAAGCTATCCCATCTGGAGAAGAAGCCGCACAGCTGTCCGCATTGCCCCAAGGCTTTTGCGCGCAGCGATCACTTGAAGGCGCACGTCCAGAGCCTGCACGGCAATAAGGAGCACAAGTGTGTGCTCTGTGATGCGGCCTTCGCCCGTGTAGATGCCCTCGATCGCCACAAGATGAGCAAGCACAATGGCGAGGGTCTTGACGCCAGCAACGAGCTGAAGCTCCAAATGAGCGAGCACACCTGCGAGTACTGCTCAAAGCGTTTCTCCAGCAAGACCTACCTGCGCAAGCATACGCTGCTCCACACGGAGTTCCTGTACGCCTGCAAGAGCTGCGACGAGACGTTCAAGGAGCGCCAGCAGCTGCGCAGCCACGAGAAGACCCACACCGGTCAGCGGAACTTCCTCTGTTGCATTTGCGGGGACAGTTTCGCCCGCAACGACTATCTGCGCGTCCATATGCGACGGCACAATGGCGAGAAGCCATACAAGTGCCGTTACTGCGTCAAGGCATTTCCACGCGCCACAGACCTTAAGGTACACGAGCGATACCACACAGGCACCAAGCCCAATCTGTGCAACACCTGCGGCAAGAGCTTCCATCGTGCCTACAATCTGACCATACATATGCGTACCCATACGGGCGAGCGTCCGTACAAGTGCGATCAGTGCCCCAAGAGCTTCAGCCAGAGCAACGATCTGAAGGCCCACATACGACGGCATACGGGCGAGCGGTACAAGTGCCCCCATTGCGATGCCTACTTCCTGCAGCTATATCACATGCGCAACCATTGCCTGAGTGCCCACAATAAGCATATTGAGACAAAGACGGGTCGCTTGCAGCGCACCGGCCTGCTGGACGAGCCCAATCACTCGCATCTGACCACTGTCGTTATGCCGCCTGCACGCTATCAGCGATCGACGCCCGATCCGCAACCAATGGCCACTGTTACGACGCAGCTGCCAGCGgccattgccacgcccattatGCATTCACCGGTGGCGTATAGTACAACGTCCCCGGTGCCGGTGCCGGTACCTGTCCCGGTGTCCGTGTCCGTTCCACTCTCAGATGCAAGCGGATTCGTTggtgcaacaacaaatgcaacaagcaCAACGGCGACGGCACCATTTGGCACCTTCAGCATAGCGCCCGTCGTGATGgCGCATCTGATGTACAATCATGGCGGAAACAGTCAGCAGAGCAATGCGAGCAAATAG
Protein Sequence: MPDTYGQFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERYDKMPHHMCDTCIKAACQAYRFKQDAEKAYRSLVAMLGRTPVTKPNSSDVCTQTEQLPMLPCGICNDKFLNILELRLHRSRQHLKTEELKCRLCDKQFQKLRQLRNHLAEQHDQKSAEAPLLRRRLECRVCQRAFSRRDHLIRHMRKAHDVPRQQEQESAATWTPNDEATMQSGDELESAAVLFNDPAACSDNENNESGYQCHTTNPISSNEDSGDDEVHAEAKESLWLHIKPEPEPELEAEAEAEPEEAEVEQVNRDRRKKKTSSKIAAHTDTEEEPEGVSKLKSASSSFSTEVKEEPLAAGGEQQLSIKQERQRADSIKVDEEYEMEAATADLFHSADEDEDDDGQSDLDEEDDEDEDEEEANVELDEHKSKLAQVEIVREYLQKPTTAKQRRRRRKQTQSETEANPENRCDVCMRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHGNKEHKCVLCDAAFARVDALDRHKMSKHNGEGLDASNELKLQMSEHTCEYCSKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQQLRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDEPNHSHLTTVVMPPARYQRSTPDPQPMATVTTQLPAAIATPIMHSPVAYSTTSPVPVPVPVPVSVSVPLSDASGFVGATTNATSTTATAPFGTFSIAPVVMAHLMYNHGGNSQQSNASK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532523;
90% Identity: iTF_00554519;
80% Identity: -