Basic Information

Insect: Drosophila hamatofila
Gene Symbol: kipf_1
Assembly: GCA_035045345.1
Location: JAWNPA010000011.1:7921605-7922720[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.4e-07 1e-05 25.9 0.5 2 23 145 166 144 166 0.97

2 8 5.4e-05 0.004 17.7 3.1 1 23 172 194 172 194 0.95

3 8 5.3e-06 0.00039 20.9 1.5 1 23 200 222 200 222 0.99

4 8 7.5e-07 5.6e-05 23.5 1.3 1 23 236 258 236 258 0.98

5 8 1.7e-06 0.00013 22.4 2.4 1 23 262 284 262 284 0.98

6 8 8e-07 5.9e-05 23.5 3.1 1 23 290 312 290 312 0.99

7 8 1.9e-08 1.4e-06 28.6 3.1 1 23 318 340 318 340 0.99

8 8 1.9e-05 0.0014 19.1 1.9 1 23 346 368 346 368 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.4e-07	1e-05	25.9	0.5	2	23	145	166	144	166	0.97
2	8	5.4e-05	0.004	17.7	3.1	1	23	172	194	172	194	0.95
3	8	5.3e-06	0.00039	20.9	1.5	1	23	200	222	200	222	0.99
4	8	7.5e-07	5.6e-05	23.5	1.3	1	23	236	258	236	258	0.98
5	8	1.7e-06	0.00013	22.4	2.4	1	23	262	284	262	284	0.98
6	8	8e-07	5.9e-05	23.5	3.1	1	23	290	312	290	312	0.99
7	8	1.9e-08	1.4e-06	28.6	3.1	1	23	318	340	318	340	0.99
8	8	1.9e-05	0.0014	19.1	1.9	1	23	346	368	346	368	0.98

Sequence Information

Coding Sequence: ATGGAAGAGGTTTGTCGCGTTTGCACAAGTAGCGCTGTCACTCTAGTGGATATATTCGCCCAGCGCGACCCATCCGACGAATCCGAGCCATGTCTGGCCGACATGCTCAACGAATGTGTTGATTATTTAGTGCGACGCGACGATCCATTTCCcaaacaaatatgtttatcCTGCGTGCTGGCTGCGCAGAATGCGTATCATTTCAAACGGAGATGCGAGCAAAGCTATCAGCACTTCTGTCAGCTGCTGCGCGAGCAGGTCACCATCAAAATGGAAGCGCAGGAAATGGAGGAAGAGGAACTAGGAGGCAATCTAGAAGTTCACATAAAGAGCGAGGAGCGGGAGTTCATAGAACCGATAGGCAGCTCAGACACAAATGAACAGCTCAGTGAACCAGTCAAACTCCCGCCCACCAAATTGGACAAATCTCAGCCTTGTCCCGTCTGCTCGAAAGTTTTCACGAATCGAGGCAGTCTCAAGCGGCATACTCGCATTCATTCCGGCGAGCGACCCTTTTCCTGCATCTACTGCCAGAAGGCCTTCAATCAGAGCTGCAACCTGGACAAGCACATGAGAGTTCACTCAGGCGAACGCCCCTTCAAGTGCGTCCAGTGCCCCAGCGCGTTCACCCAGAGCAATCATCTGACCAATCACATACGGATTCATGCGCACGCAGCACGCAGATTTAGCCACATCGAGCGACCCCACAAGTGCACCGAGTGCGCAAAGGCCTTTACTAGCAAATGGAATCTGAAGGAGCACATACGCGCCCATTCCGGGTCCTTCAAGTGTTGCCTCTGTCCCAAGACATTCGCGAATCGCGGAGATCTGCAGCGGCACAGTCGGGTTCACTCCGGCGAAAGGCCATATAAGTGCTTGCACTGTGCAAAATCGTTCACCCAAAATGTCAATCTGGAGAGGCACAAGCGTGTCCATTCCGGGGACAGACCCTATCAGTGTCCAGATTGTCACATGGCCTTCAAGCAGAGCAGCCACTTGGTCAATCACATTCGCACTCATTCGGGAGAACGGCCATTTCAGTGCCTGGACTGCATGAAGAGCTTCACCCGGAGAGAGTATCTTGAAAAGCATAGTCGAATTCACTCATTACAATAA
Protein Sequence: MEEVCRVCTSSAVTLVDIFAQRDPSDESEPCLADMLNECVDYLVRRDDPFPKQICLSCVLAAQNAYHFKRRCEQSYQHFCQLLREQVTIKMEAQEMEEEELGGNLEVHIKSEEREFIEPIGSSDTNEQLSEPVKLPPTKLDKSQPCPVCSKVFTNRGSLKRHTRIHSGERPFSCIYCQKAFNQSCNLDKHMRVHSGERPFKCVQCPSAFTQSNHLTNHIRIHAHAARRFSHIERPHKCTECAKAFTSKWNLKEHIRAHSGSFKCCLCPKTFANRGDLQRHSRVHSGERPYKCLHCAKSFTQNVNLERHKRVHSGDRPYQCPDCHMAFKQSSHLVNHIRTHSGERPFQCLDCMKSFTRREYLEKHSRIHSLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00554514;
90% Identity: -
80% Identity: -