Basic Information

Insect: Drosophila hamatofila
Gene Symbol: -
Assembly: GCA_035045345.1
Location: JAWNPA010000019.1:6621096-6623375[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 5.3e-06 0.00039 20.9 0.6 1 23 292 314 292 314 0.99

2 9 7.5e-07 5.6e-05 23.5 2.0 1 23 320 342 320 342 0.99

3 9 1.8e-08 1.3e-06 28.6 0.5 1 23 348 370 348 370 0.99

4 9 2.3e-05 0.0017 18.9 1.9 1 23 376 398 376 398 0.98

5 9 0.00011 0.0082 16.7 0.0 1 23 405 427 405 427 0.98

6 9 0.00084 0.062 14.0 1.2 1 21 433 453 433 455 0.96

7 9 6.8e-08 5.1e-06 26.8 0.7 1 23 461 483 461 483 0.98

8 9 1.1e-07 8.2e-06 26.2 2.8 1 23 489 511 489 511 0.99

9 9 7e-07 5.1e-05 23.7 0.5 1 23 517 539 517 539 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	5.3e-06	0.00039	20.9	0.6	1	23	292	314	292	314	0.99
2	9	7.5e-07	5.6e-05	23.5	2.0	1	23	320	342	320	342	0.99
3	9	1.8e-08	1.3e-06	28.6	0.5	1	23	348	370	348	370	0.99
4	9	2.3e-05	0.0017	18.9	1.9	1	23	376	398	376	398	0.98
5	9	0.00011	0.0082	16.7	0.0	1	23	405	427	405	427	0.98
6	9	0.00084	0.062	14.0	1.2	1	21	433	453	433	455	0.96
7	9	6.8e-08	5.1e-06	26.8	0.7	1	23	461	483	461	483	0.98
8	9	1.1e-07	8.2e-06	26.2	2.8	1	23	489	511	489	511	0.99
9	9	7e-07	5.1e-05	23.7	0.5	1	23	517	539	517	539	0.96

Sequence Information

Coding Sequence: ATGGCCGTGCAGCTGAAGAATGCGTATCACCATCTGCCGCTGACCATAACGCCGATACTCTGCCAGCCGCTGCTGACGCCAGCGCCGACGCCGCCGAAGCCGGAGCCGCCAGACTTGACCTTTCACTGCATGTGCTGTGCCGAGTACTTTGTGCATCCACTGGCGCTCTACCAGCACATGAACAGCAAGCATCCGAACGAGGCGacgccacagcaacaacagcagcagcagcagcacgagcTGGAGCAGGCGGGTGAGGAGGACAGCACAGATTATAGCTGGATCTTTGAGCCCGTTTGTGAGCTGGAGGTGGCTGCGGATGCGGCGCCGTTGCGCAGCGACGATGACAGCGACTCGAACAGCGAtgaggaggcggaggagggCAGCGAAGCGGACAGCGACAATGatagcgacagcagcagcagcagcaacaacagcagcagcggcagctcctCGAGCAGcggcaccaccagcagcagtggcGGTGGTGGGGTAGGCGGCGTCAATAGCAACTCCAATACGCAGCCGGGCTTGGAGAATGGCGCCTATGTGGAGGTGGCCTCGACACAGCCCATACGTGGCCTGCTGCCCGGCTTGCAGCCCAATGAGTACCAGCTGCAGACAGCTGATCCGCATGAGTCCACCTCCATCATACTGCTGCAGCCGTCGCTGAGCATTACACCAGTGCCGGTGGTGCCGTTGCCAGtggtgcaacaacaacaggcgcCGCCGCCGTTGCTGCCCACACTGAGTCTGGAGCCGGCGCCGATTAAGCGACGTCGTGGACGACGCAGCAAGACGAATGCCAGCAGCGATGGCCAGGgcgctgcagccgctgccgtGGCCCAGCTGGGCGCCAATGGGCAGAAGTGCTTTCAGTGCACCCACTGTGAGGCATCGTTTCCCAATGCCGGCGATCTGTCCAAGCATGTGCGCTCCCACATCTCGAACAAGCCCTTCCAGTGCTCCATCTGCCAGAAGACCTTCACACACATCGGCAGCCTCAACACGCACATACGCATCCACAGCGGCGAGAAGCCCTACAAGTGCGAGCTCTGCCCCAAGGCATTCACCCAGTCGAGCAGCCTGATGGTGCACATGAGATCTCATGCGGTGCGCAAGCCGCATCAGTGCGTGCAGTGCGACAAGGGCTTCATCAACTAcagctcgctgctgctgcatcagaAGACGCACTCGGCGCCCGTGGAGAGCTTCGTGTGTCCGGAGTGCGAGCGGGAGTTTAAGGCCGAGGCGCTGCTGGATGAGCACATGAGGATGCATACCCAGGAGCTGGTCTATCAGTGCGCCATTTGCCGGCAGGCATTCCGCGCCAGCTCGGAGCTGGTGCAGCACATGAAATGCCACATGGGCGAGAAGCCGTTCACCTGCTCCCTGTGCGATCGCTCGTTCACGCAGTCGGGCAGCCTCAACATCCACATGCGCATCCACACGGGCGAGAAGCCCTTCCAGTGCAAGCTGTGCGACAAGTGCTTCACCCAGGCCTCCAGCCTGAGCGTGCACATGAAGATCCATGCGGGCGAGAAGCCCTTCCCCTGCCACATCTGCGGCAAGGCCTACAGCCAGCAGGCCTATCTCAACAAGCATGTCCAGGCACATGCCATGGATGCGACGCCTACGCACCAGGCGATGCCGCCGATGCCCGCGGCGCCAGCGAAGGAGACGCTCGTTTGCATTGTGTGCGGGGCGCTGCATGCGGACGCCACGGCTCTGGCGCTGCATGTGACGCGGGAGCACACGGCGCTGCTGGACAACATGAAGCAGGCGACGATACCGCAGGCGCCGCCGGCGACGGCCAAATGCAGCGCCGTGGAGCgccaggcgcagcagcaggcgtACATGCAGCGTGTGCAGTCGATGCTGCAGCAGAtgaatcagcagcagcagcagcaaccggcCATGGACTCGGCTGgcgaggatgaggaggagctGGACGACGAGGATGAGCTGGACGAGGATGAGGTGGTCGAGCAGAACGAGGCACAGCCAGTGGCCAGCatcgacgatgacgatgacgacgatgatgaagacgacgtcgacgacgatgacgatggtatcgatgatggtgatgatgaagatgaagatgaagatgatgcCGTTGATGacgatgagcagcagctgataaCGGATACAGATATGTATTACGATATGCCCGGTGATTTTGCCGACATGGAAGTGGGCTGCGAGGAGGAGGTGTGCGGCGATTTTATTGAGAATGACGATTACGCTGCCGAGGAGGAGGTCTACACCGAGGACCTATAA
Protein Sequence: MAVQLKNAYHHLPLTITPILCQPLLTPAPTPPKPEPPDLTFHCMCCAEYFVHPLALYQHMNSKHPNEATPQQQQQQQQHELEQAGEEDSTDYSWIFEPVCELEVAADAAPLRSDDDSDSNSDEEAEEGSEADSDNDSDSSSSSNNSSSGSSSSSGTTSSSGGGGVGGVNSNSNTQPGLENGAYVEVASTQPIRGLLPGLQPNEYQLQTADPHESTSIILLQPSLSITPVPVVPLPVVQQQQAPPPLLPTLSLEPAPIKRRRGRRSKTNASSDGQGAAAAAVAQLGANGQKCFQCTHCEASFPNAGDLSKHVRSHISNKPFQCSICQKTFTHIGSLNTHIRIHSGEKPYKCELCPKAFTQSSSLMVHMRSHAVRKPHQCVQCDKGFINYSSLLLHQKTHSAPVESFVCPECEREFKAEALLDEHMRMHTQELVYQCAICRQAFRASSELVQHMKCHMGEKPFTCSLCDRSFTQSGSLNIHMRIHTGEKPFQCKLCDKCFTQASSLSVHMKIHAGEKPFPCHICGKAYSQQAYLNKHVQAHAMDATPTHQAMPPMPAAPAKETLVCIVCGALHADATALALHVTREHTALLDNMKQATIPQAPPATAKCSAVERQAQQQAYMQRVQSMLQQMNQQQQQQPAMDSAGEDEEELDDEDELDEDEVVEQNEAQPVASIDDDDDDDDEDDVDDDDDGIDDGDDEDEDEDDAVDDDEQQLITDTDMYYDMPGDFADMEVGCEEEVCGDFIENDDYAAEEEVYTEDL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00617041;
90% Identity: iTF_00551725; iTF_00473201; iTF_00540506; iTF_00554513; iTF_00544630; iTF_00545382; iTF_00479614; iTF_00549685;
80% Identity: -