Basic Information

Insect: Drosophila hamatofila
Gene Symbol: -
Assembly: GCA_035045345.1
Location: JAWNPA010000020.1:23740242-23744893[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0011 0.082 13.6 1.3 1 23 219 241 219 241 0.97

2 26 0.047 3.5 8.4 2.0 1 23 247 269 247 269 0.97

3 26 0.46 34 5.3 1.0 2 20 301 319 301 322 0.94

4 26 0.019 1.4 9.7 0.9 1 23 401 424 401 424 0.93

5 26 0.38 28 5.6 2.2 2 23 435 458 434 458 0.93

6 26 1 76 4.2 0.3 1 20 464 483 464 485 0.90

7 26 0.05 3.7 8.4 1.3 2 23 499 520 498 520 0.97

8 26 0.68 50 4.8 1.6 1 23 600 623 600 623 0.94

9 26 0.0057 0.42 11.3 0.0 1 22 632 653 632 653 0.96

10 26 0.049 3.6 8.4 1.1 1 23 662 685 662 685 0.96

11 26 0.0011 0.083 13.6 0.2 2 23 717 738 716 738 0.97

12 26 1.5e-05 0.0011 19.5 5.7 1 23 746 768 746 768 0.99

13 26 0.049 3.6 8.4 1.5 1 23 916 939 916 939 0.92

14 26 1.2 92 4.0 1.9 3 22 948 967 947 967 0.91

15 26 2.6 1.9e+02 3.0 0.4 1 23 976 999 976 999 0.85

16 26 1.1e-05 0.00084 19.8 1.9 1 23 1024 1046 1024 1046 0.97

17 26 0.00015 0.011 16.3 0.9 1 23 1053 1075 1053 1075 0.98

18 26 0.028 2.1 9.2 0.0 2 21 1102 1121 1101 1122 0.94

19 26 0.012 0.87 10.4 4.1 1 23 1167 1190 1167 1190 0.96

20 26 0.0075 0.55 11.0 0.9 1 23 1227 1250 1227 1250 0.95

21 26 0.015 1.1 10.0 3.1 1 23 1278 1301 1278 1301 0.97

22 26 1.4e-05 0.0011 19.5 0.1 2 23 1329 1350 1328 1350 0.95

23 26 4.9e-05 0.0036 17.8 2.9 1 23 1356 1378 1356 1378 0.99

24 26 2.4e-06 0.00018 22.0 2.0 1 23 1384 1406 1384 1406 0.97

25 26 6.1e-08 4.5e-06 27.0 2.4 1 23 1412 1434 1412 1434 0.99

26 26 0.00019 0.014 16.0 0.5 1 23 1440 1462 1440 1462 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0011	0.082	13.6	1.3	1	23	219	241	219	241	0.97
2	26	0.047	3.5	8.4	2.0	1	23	247	269	247	269	0.97
3	26	0.46	34	5.3	1.0	2	20	301	319	301	322	0.94
4	26	0.019	1.4	9.7	0.9	1	23	401	424	401	424	0.93
5	26	0.38	28	5.6	2.2	2	23	435	458	434	458	0.93
6	26	1	76	4.2	0.3	1	20	464	483	464	485	0.90
7	26	0.05	3.7	8.4	1.3	2	23	499	520	498	520	0.97
8	26	0.68	50	4.8	1.6	1	23	600	623	600	623	0.94
9	26	0.0057	0.42	11.3	0.0	1	22	632	653	632	653	0.96
10	26	0.049	3.6	8.4	1.1	1	23	662	685	662	685	0.96
11	26	0.0011	0.083	13.6	0.2	2	23	717	738	716	738	0.97
12	26	1.5e-05	0.0011	19.5	5.7	1	23	746	768	746	768	0.99
13	26	0.049	3.6	8.4	1.5	1	23	916	939	916	939	0.92
14	26	1.2	92	4.0	1.9	3	22	948	967	947	967	0.91
15	26	2.6	1.9e+02	3.0	0.4	1	23	976	999	976	999	0.85
16	26	1.1e-05	0.00084	19.8	1.9	1	23	1024	1046	1024	1046	0.97
17	26	0.00015	0.011	16.3	0.9	1	23	1053	1075	1053	1075	0.98
18	26	0.028	2.1	9.2	0.0	2	21	1102	1121	1101	1122	0.94
19	26	0.012	0.87	10.4	4.1	1	23	1167	1190	1167	1190	0.96
20	26	0.0075	0.55	11.0	0.9	1	23	1227	1250	1227	1250	0.95
21	26	0.015	1.1	10.0	3.1	1	23	1278	1301	1278	1301	0.97
22	26	1.4e-05	0.0011	19.5	0.1	2	23	1329	1350	1328	1350	0.95
23	26	4.9e-05	0.0036	17.8	2.9	1	23	1356	1378	1356	1378	0.99
24	26	2.4e-06	0.00018	22.0	2.0	1	23	1384	1406	1384	1406	0.97
25	26	6.1e-08	4.5e-06	27.0	2.4	1	23	1412	1434	1412	1434	0.99
26	26	0.00019	0.014	16.0	0.5	1	23	1440	1462	1440	1462	0.97

Sequence Information

Coding Sequence: ATGTTGCCGACAGATATTTGCCGTACATGCACGCTGCATGATGATAGGTTGCTTCCGCTTACGACCCGCACtgataaatatgcaaataaaagtttgaaTGACATGTTACTCGAATTGACACAAAATGATccCCTGCAAGAGCATACGGATGACAGTCTGCCGCAGCACTTGTGTATTGGCTGCTTGCACAAGTTAGAGGCTGCGTACGCGTTCGTATTGCAAGCGCGCCAGGCTCAAgagcaattgctgttgcagctgcgcaAAGGCTCGCAGACACAGTGTTTAGATGAGATGCCTATAGACATAAACTTGGAGCACATCAAAACCGAAACGATCGTTGACATGCAACTAACTAGCAAAGCTAAGAGCGAAGAGGATGAGGCTGAAGAGAGGGAGCAAGTGATGGCTGCACTGGCCATTCCAGCCCTGAAGTGGCAGCCAGACAGCGACAGTGAGAGCAATCAGACTGCTGCTGATAATCAGGATATGGACTTTAAGCCTAAGCAGTTGCGGCGCAGTGCACGTAAAGCCAAAGCCTGCACAGATAGCGAAACTGAAGCAACATCTGCCCATGCGAATCCCTTGCCCATCAAACGCCGTCGAGGTCGCCCAGCACGCCTGCTCAATAAGGAAGCTATCAACGAAGAAGGAAGGCATGTGTGTGAGGTTTGTGGAAAGAGCTTTTCGTGGTACCGCGACATGCAGCGCCACTCGCGCATTCACTTCGAGCAAGCGACCTTCGTGTGCGACAGTTGTGGCAAGAGCTTTTTGCGCAAAGACAAATATATGTTTCATCTTCGCTCGCACGAAAAGCGAGTAGCCAAGAGTCAGGCCACACAACAGAGCGGCGAATGGCGCTTTGCTGAACGCCTCTACAGCTCCGGCCGGCTCAAGCGTGCAGAGTGCAAGCTGTGTGGCTCGAAATATCAACGTATAGGGGAGCTGCGCGAGCATATGGCGTGCCATAAGAGCATTGAGACATTGTCTAAACTGAGTCTAGAGAGTGATGTTATCAGGGAACAGTTTGCCAAAGAGCAAAGAGAACAGCAGTTAGACCTGACGCTGATCAAGCAACATGTGTGTGCAGACATTGCCAAAGGACGTGGTCAGCTGGACAGATATTGCGCAGTGGTCAACGCGTACGGCTATGAGCTCGGTCTTAGCGACTCAGACGAAGACGCAGCTCACCGGTCGCCTAAATACCAGTGTCTTCCATGCAACATCAATTTCACGCGCAAATATCGCCTTATGCGGCACACACTGGAGGAGCACACACAGGCGGAAACAGCGGTGTCGTGGCAACGCTGTGATGTTTGCCAAATTGGTTTTGTATGTCCTGAAATGCTCGAGCAACATCAACGCACGCAGTGCCACAACAAACTGAAGCGGTACAGGTGCCCCAACTGCCCAGGTAAATTCATTTGGCTGCAGAATCTGGAGCAGCATGCGTGCTCGCAAGTTAGCAAGCGGCTCGACGAGCACCGGCAGCTAAAGCAGTGCTGTCTCTGTGATATCCAATTCAACAGCATGCTTGAATTACGCGCCCATTTACTTAGCCATCAAGATGGAAGCAGTGGCATACATCCAGAGCAACAGGCGACCTTCTTTCGCACCTACTATCCCAACGGCCTTGATTGCAGCTTATCTGAGCTGAGCGCACGAATTGCCGCCGATTTTAAGGCGGAGGATTATGGGCGGTACTTTAATGCCAGATCGAGGAACGGCGAAGAGCTCGATTTCTTcgcctctgactctgacttAAGTGATGCGGACCACCTGAGTTCTGGCGGTACGCTTCATATATGTTGCCTGTGTGGCGAGACAAAAGCGCGCCTCAGTCAATTGCTCGAGCATCAGGCAAGCCAGCATAATGAGGTGCTGGAGAGGCTCCCATACGTCTGTGACGACTGCGATTTGAGTTTCGTTGCTGATGCGCTGCTCCAACAGCATCGCCGACGAGCTTGTGCCAAGCAGCATGCCAAGTACGACTGCCAGCTATGCAGTCAGCGCTTTTACTGGCTTTCCAATTACAAGTTGCATATGCAGGTACAACATGAGACTCAAGCCGAGCTGGAGGCGGATGTTGTCAATGAACAGGAGCGGGATCCAAGAATGAGAAGCAAGCGTCAGTCCACAGCTGCCAAGTTGCAGTGCGGCGAATGTGAAAAGGTGTTCATCTGGCCGAAGGATCTGACGCGTCACAAGCGCCTACATCAGCCAACAGCTTCGGCACAATACCAATGCTTGCACTGCGACCGCAAGTTCCATCGCAAGGATGGGCTGAAATCTCATATGCGCGTGCATGGCGAACAGCAGGTCGACGCTTCGGTTGTCAGTGATCAAGTTCCGTCCATGCTGCAGCGCATGCCAGTGGTGCTGATCCAACTGTGTCGGCCTAATGGCTGCAAGCAAATTCAATGCATGATATGTCTCTCGCAGCACACTAAAATATCTGATCTTCGCACGCATTTGCTTAATCATCAGTATTCGGTCGAATTTGGAGACGAGCGGAGCCAACCGGACAGCATAGCTGGCATTTCACGTTCTCTGTATCCAGAACTAGCCGCACCATTGGAGCAAAAGCAATTAATCGAACGCATTAAAAGTGATGTGACAAAAGGCGTAGAGCTGGAAAGATTCATATCCATTACCAACGAGGCGGGCATCGAGCTTAGCCTGGACAGCAGCGAGACGGAAACCGATTCGGACTCTGCCGACACAGTCAGAAGCAACAGCGGACAACTCTATAACTGTGAGCTATGCCAGCTGAAGCTGTCGCGCAAGCATCAGCTTTACGCCCATGAGCTGGAGCAGCACTCGTGGCAGCAGGCAACTCGtgtttgcagctgctgccaggcGAGATTCGTTaatgagcagctgctgcagcatcacTATCGCACGCTCTGTCGCAACGCACACCGACGTTTCCTCTGTCGTAAATGCCCATTACGTTTTCGCTGGCGCGAGAATATGAAGTTGCACTCGGACGTGGCGCACAACGAAGCCAGAGGTGAGCAATCGAACTTGGGCATTAAGTTAAACGGAACGCGCCAGTTGCCAAACTTTAGTTACGACTGCACAGAATGCAATCGAagctttaaaatgcaaaaggaTCTCACCAGGCACACTCTGATGCATGCCCAGGAGTCAAGCATTTATCGCTGTCGCTGGTGTGCACGACGTTTCTATCGTCAGGCCAATCTACTGCAGCACATTGAGCGTCACGGCATTAGCGCCGAACAGCTGCCCTATGCTGAGGCACTGCTCAATGCCAGTCGTCATCCGCATGGTCAGAAGTGTATCCAGTGCAAGGTGTGTAACGTGACCTACCCCACCATTGCTGCGCTGCGCAGCCATCTTCAATCGGCGACAGCAGGAACTCATCATGACTATGGCTCGTTGCTCAACTACTCCATTACCAATCAGCTGGGATACGAGCTGCATCTGGAAGACTCGGAAACGGATGAGGAGGCTAAGCCACCAGGCACGCCTACGCACTACACCTGTAGCATATGCCAGCTGCGCTGTGCGCGCAAGTTTGAgctgcatcagcatcagcaagcAATGCATCGACTGGAACGTATAAACGAGGGCTGCGATGTCTGCATCTTTAAGAGTGTCTCAACAGATCTCATTGCCTACCATCAACGCGTGTTGTGCAATAACACGGAGAAACACTTCAAATGCTCCAAATGTGGCTACAAGTTTATGTGGGAAACGAATTTGTTGCAGCATATGGAATTGCAGCATCCCAGCAGCGATGGAAGCGAAACGCAGCAGAATCCAAGTACGTTGTCTGCGCGGGAGGTACCCAGTGCTGAGTGCCAGATTTTTCAGTGCGGTCAGTGCCCTAGTAAATATAATCGCAAGGATCGACTCACTGCACATGTCAAGAAATGTCATGCAGCGGGAGCAAATGGCCCCACGGCTGCAGCGGGGAAGCTTATGAAAAATTCAACTGGCGCCAAGCAGCAGAAAAGTTTTCTGTGTGCTTTCTGTGGCAAGGCGGTTAGCTCCTCCTCCAATTtgattatacatatacgtcGCCATACTGGCGAGAAGCCTTTTAAGTGTGACTACTGCGACATGGCATTTCCACGTTCCTCCGATCTACAGTGCCATCGACGCACCCACACAGGCGAGCGGCCTCACGTCTGCACCGTTTGCCAGAAAGGCTTTGCCCGATCGTACAAGCTGCAGCAACACATGCGCATCCATAATGGCGAGCGGCCATATAAGTGTACTTATTGTGACAAGAGTTTCACTCAGTCAAATGATCTGACGCTCCACATACGACGGCACACAGGCGAGCGTCCCTATCAGTGCAATACGTGCGGCGAACGTTTTATACAGGGCACAGCCCTGAAAAATCATCGCCTTCAACATGGACACCATGATACGGAAGTGGACCAGGCCAAGGAAACTAATTAA
Protein Sequence: MLPTDICRTCTLHDDRLLPLTTRTDKYANKSLNDMLLELTQNDPLQEHTDDSLPQHLCIGCLHKLEAAYAFVLQARQAQEQLLLQLRKGSQTQCLDEMPIDINLEHIKTETIVDMQLTSKAKSEEDEAEEREQVMAALAIPALKWQPDSDSESNQTAADNQDMDFKPKQLRRSARKAKACTDSETEATSAHANPLPIKRRRGRPARLLNKEAINEEGRHVCEVCGKSFSWYRDMQRHSRIHFEQATFVCDSCGKSFLRKDKYMFHLRSHEKRVAKSQATQQSGEWRFAERLYSSGRLKRAECKLCGSKYQRIGELREHMACHKSIETLSKLSLESDVIREQFAKEQREQQLDLTLIKQHVCADIAKGRGQLDRYCAVVNAYGYELGLSDSDEDAAHRSPKYQCLPCNINFTRKYRLMRHTLEEHTQAETAVSWQRCDVCQIGFVCPEMLEQHQRTQCHNKLKRYRCPNCPGKFIWLQNLEQHACSQVSKRLDEHRQLKQCCLCDIQFNSMLELRAHLLSHQDGSSGIHPEQQATFFRTYYPNGLDCSLSELSARIAADFKAEDYGRYFNARSRNGEELDFFASDSDLSDADHLSSGGTLHICCLCGETKARLSQLLEHQASQHNEVLERLPYVCDDCDLSFVADALLQQHRRRACAKQHAKYDCQLCSQRFYWLSNYKLHMQVQHETQAELEADVVNEQERDPRMRSKRQSTAAKLQCGECEKVFIWPKDLTRHKRLHQPTASAQYQCLHCDRKFHRKDGLKSHMRVHGEQQVDASVVSDQVPSMLQRMPVVLIQLCRPNGCKQIQCMICLSQHTKISDLRTHLLNHQYSVEFGDERSQPDSIAGISRSLYPELAAPLEQKQLIERIKSDVTKGVELERFISITNEAGIELSLDSSETETDSDSADTVRSNSGQLYNCELCQLKLSRKHQLYAHELEQHSWQQATRVCSCCQARFVNEQLLQHHYRTLCRNAHRRFLCRKCPLRFRWRENMKLHSDVAHNEARGEQSNLGIKLNGTRQLPNFSYDCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNASRHPHGQKCIQCKVCNVTYPTIAALRSHLQSATAGTHHDYGSLLNYSITNQLGYELHLEDSETDEEAKPPGTPTHYTCSICQLRCARKFELHQHQQAMHRLERINEGCDVCIFKSVSTDLIAYHQRVLCNNTEKHFKCSKCGYKFMWETNLLQHMELQHPSSDGSETQQNPSTLSAREVPSAECQIFQCGQCPSKYNRKDRLTAHVKKCHAAGANGPTAAAGKLMKNSTGAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQHGHHDTEVDQAKETN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509945;
90% Identity: -
80% Identity: -