Basic Information

Insect: Drosophila gunungcola
Gene Symbol: HIVEP2
Assembly: GCA_011057485.1
Location: WTSR01005183.1:2532421-2540095[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00092 0.085 13.2 0.2 1 23 135 157 135 157 0.98

2 8 0.00016 0.015 15.6 2.9 1 21 163 183 163 187 0.89

3 8 0.015 1.4 9.5 0.1 1 19 617 635 617 638 0.93

4 8 1.5e-06 0.00014 22.0 2.0 1 23 1220 1242 1220 1242 0.99

5 8 6.1e-06 0.00057 20.1 5.3 1 23 1248 1272 1248 1272 0.92

6 8 6.8e-05 0.0063 16.8 2.7 2 23 1683 1704 1683 1704 0.97

7 8 0.00042 0.039 14.3 1.2 1 23 1710 1734 1710 1734 0.91

8 8 0.0013 0.12 12.7 2.7 1 23 1755 1779 1755 1779 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00092	0.085	13.2	0.2	1	23	135	157	135	157	0.98
2	8	0.00016	0.015	15.6	2.9	1	21	163	183	163	187	0.89
3	8	0.015	1.4	9.5	0.1	1	19	617	635	617	638	0.93
4	8	1.5e-06	0.00014	22.0	2.0	1	23	1220	1242	1220	1242	0.99
5	8	6.1e-06	0.00057	20.1	5.3	1	23	1248	1272	1248	1272	0.92
6	8	6.8e-05	0.0063	16.8	2.7	2	23	1683	1704	1683	1704	0.97
7	8	0.00042	0.039	14.3	1.2	1	23	1710	1734	1710	1734	0.91
8	8	0.0013	0.12	12.7	2.7	1	23	1755	1779	1755	1779	0.92

Sequence Information

Coding Sequence: ATGACGCTACAACAGATGGCAGCAGTCAGCAGCAACCAGGAGCCAGTGGCTCCAGCCAATGTGGTTAATACGATGAGCAACATTAGTAGCCAGGCCAGCGTAAatgccacacccacacccGCCACNNNNNNCGCCACCGCCAACGCCACCGATGAGGCTTCGCTGGGGGATTGGTCAAATATTTCACGCTATCTGCACAAGAAGTTCAAACGTTTGGCCAGCACCACCGAAGTGGAGAGCAGCCACTCGACAACGAACGGTAGCTNNNGTGCACATGATGCCATCCGCACCACATCGATGTCCTCGAACAGTTCGCTatcaccaccaccgccgccgatGATGATGCCGCTGGCCAATGGAATGCCAGCAGTAGCGAATCCTGCAGGCGAAAAGTCCGGACGCTATGTTTGCCCATACTGCAATCTGCTGTGTGCCAAGCCCTCGGTGCTGGAGAAGCACATACGTGCCCACACCAACGAGCGACCCTATCCATGCGACACCTGCGGCATTGCGTTCAAGACAAAGAGCAATTTGTACAAACATTGCCGCTCCAGATCGCATGCAGCCCGAGCTCGGGGCTTGGAAGTGCCTGCGGATGCAGATGATGGATTGTCCGATCAGGATGCCGAATTGAGCAACAGTAGTTCGGAGCTGCCAAGTCGCGCTGGTTCGCCCTACGATGAGCCCATAAGTTCGCCCACACCCTCACCTTCCACGCTGTCGGCGGCCAAGAGTGCCTACTtgcagcagccgccgctgcCACAGCACTTGCAACAATTGCCGCTGGGCTCACCGGCTGCCGGTACTTTGCCACCCACCACCGCGGATAATCTGCACTCGGCCACTGCCCAGCATCGCCCGTCGATTGACTACAAGCCATATAAGCCCAACACGCAGATGAAGATGAAGCACCACATCAACTCGCATCAGATCCAGTtgcagatgcagcagcagcaatcacTGCTGGCCCAGCAATCGCTGTTGGCCGCCATGCCAGTGCCACCCGGATCGGTTTATTACCTGGGAGGGCAACCGCCYTATTACAACCAAGATGCTGCGGCTGCGGCCATTCACCAGCAAGCCTTGCTGGTGCGAGCCAACAGCCAGGTTTCCAGTGTAGCAANNNCAGCACCTGCCACTCCCACACCCAATGCAAATCTCAGCAGTTTTGCCAGCTCCAGTGGCGGCATGCAAGTGAATGTGGCCAAAGTGCAAGAGCACATTTCCAAGTTGATCTCTCAGAATGAAGCCATTGTGGAGAACAAGGAGATACTGCTGCAAAAGAAATACCCCAAGCAGCTGAGTCGTTCCCGCAGCTTCAACAatgccaacagcaacagtgcAACGCAgcacggcagcagcaacacgacGGCACTGCATGCGAACAGCAGTCATAATATCAATGCACAGATGCCAGAGCGCGAGACGAAACAACTGGAACCACCAAATGGCTTGGCTAAAAGGAACACTTATAAGCCAGCAACAGTAGCAACAACGCCTgtgaaacagcagcaacaactgccgCCCCCGCCCTCTCCGCTGCCCATGCAAACGATGCAATACCGCCAGGATCCGGCCACGCCAGTGCCTAAAGTGGAACAACCCGCGGCAGCAGTGCACGTGATGCCTTTGAACCTGTCAGCGAAGCCCAAACCAACTTTGGTCACAGTGCCAGTGAGTTCCCTGCCCATCAGCTCTGTGGCATCGACACCGGCGAGCTCAGCGAATCCATCGAGCAGCGCCAAAACTGCCGCACCTCCTGCCCAGGTGAACAACTCGATCATCAAGAATCTGCTGCTTAATGCTCGAGGATTGGCGGTGCCAATTGGCGAGGGCGATGATGCCGTCTACTCGTGCCCCATCTGTGCCAATGAGTTCCGCAGTGCGGACGAACTGAAGCTGCACAACAGCACCTACTGCCAGGATGCCAGCTCCAGTGCGCCCATGAGTCCCGCCTCGTCGCCCTTCCGCTCCAATTCRATCTCGCTMAGTCTGCCGGAGCTGAAGAGTCACATGGCCAACTCGAAGAATCCATTGTCACTGGCCAAGCTGGCGTGGTCGCAGTTGAAGACCAAGAGGAGCACTCTGATTGAAGCACTGCGCTTTGTGGATGCACCACTGCCGTCGCCAGGTCCTCTGCTGGGCAAAACTCCCCTGGTGGACTATTCGCGACAGAGTGCACCGCGCAAGCCCCAGGATGCGGTGGTCATAACCAAAATGCACGAGGATCGACAGTTTGCCTTGCGCGACATTGAGGCTCAGCCGGCAAAGCGTGTGAAGACCAGCGATCAGGTCGTANNNNNNNNNGCCTCCGTNACGCCAAGCTTCAATTTCTCCTTCAACAACAATGGTGTGCCCGAGTTGCAGTCCAGCAAGGAGGAGCGCCTTCGCCGGTTCACCTCCTCGGGCGGCAGCATGATACCCATTTCGGAGTGCCCGGAYATGGACAACAGCCCCAAGATGATACGAACGCCGTTGCTGTCCGGCGGCAGCTTCCAGGATGTCTCCGTGAAGGCCAACAACNNNNNNNNNNNNNNNGAGGCAGGACCTTCGAGCAAGGAGCGCAAGCTGATGGCACTGGTCAGTGGCAGTGGACTGCTCGGCGTTAGCACTGGCCCCCAGCACTTTCAGTTTCCGCCCATCAACTCGATAACTGCCTTCAATCCGTTGACTTTGCCACCCATGAGCGAACTGAAGGCCCTGTCGCCATTTGGTGGGGTTCAGAATCTGCCCAGCGAGTTCAGCCGACAGCCACCAACGCCTGCCCAGCGACAAGCGTTGCAATGGAACAGCAAGGAGACGGCGAAGAAGGCTCCATTCAACTTTCTACGCATGGCCGATAACGTGAAGACGGCGGAANCCGAAGTGCGTCACTTCAATCTGGACAGCGTTATGGCTGGCAAACAGCAGGAGTTGACCTTGCAACCGCTCCATGTGGAGACTCCCAATGGCAGTGCCACCGAGGAGGTGGCCAGTTCCTCATCGGGATCGGCCAAGTCCAAGTTCCTGCGACCCACTAGTTTGCCRCTGAAACCAGGAACCTTTACACCGAAACGCCATCATGGCATAACGCCCACGGCCAACACACTACCACTGATCTCGCCGGAAACTCCCAGGCCCTCGAAATCCTGTGTGCAACTCTATCTAAATGGACATGCCTACACCTATTTGGGTCTCAAGTGCAGCACCAAGATGTTCTACTGTACGGTGAACTGTCCGCAACCCTCGTATGTGGCCGGAATGCACAAACTGTCGATGTACAGTGTGTGGCAGGTGTGCGAGGAGAATCAGCCACATCCGCTGGGCTTCAAACTGAAGCAGGTGATGGCGCTGTATGACTCACGTCAGCGGATGCTGGGAAATGGCAGTTCCACCGCAATGGCTGGCTTGGGAAAACTGAGCTACAATCTGGTGGCCTCACAGCAGACAGTGTGCTCCACGTCGACCACGACCAGTAGCAGTGCCTTCTATCGGGGACCCGTGAAGACGCCACCCACTGTCACAGTGGCCGCGCTCAGCGAGGCAAATGTGGCGGCCAAAGCGAACGAGGAGGCGCAGGCCAAGAAGCTGGAGACGAGTCCGTCGGGACAGCCCCTGGTGGGTGGCTATGAGTCGCACGAGGATTACACGTACATACGCGGCAGAGGAAGGGGCCGGTATGTTTGCTCCGAGTGCGGTATTCGCTGCAAGAAGCCCTCCATGCTGAAGAAGCATATACGCACCCACACGGATGTGAGGCCATTTACCTGCAGCCACTGCAATTTCAGTTTCAAGACCAAGGGCAATCTGACCAAGCACATGCAATCGAAGACCCACTTCAAGAAGTGCATTGAACTGGGCATCAATCCGGGACCAATGNCNCCAGATAGCGAGTTCCTGGATGTGGACATGGACTTTGACCAGCAGTCATCCACTTCGGCCGGCGGACGCACTTCCTCAATGGCTGGCGAATCCGATTCCGATGACTACAGCGACAATGAATCGGAAAGCAGTGATACCGATGAATCCAAGTCGCGCTTAAAAGAACACGAGGCAGCCAGGGGTCTGCTATCGCTATCGATGACGCCGCCCATTCCGCAGAGTGTGTCGCCCTATCCGCAGCWGCAGGATACCCCTCTGCCGGCGGCCAGTCCTGCCAACAGCATTGGCTCTTCGGGCTCGCTGCCYAAGCGATTGGTGTGCTCTTTTACGTCGCCCAAGCCACCGTTTGACTACCAGAAGCAGGAACAGTATTACTCCAATCCGGAGGAGTCCAAGCCCAAGCGCAGCGTGGCCAGCGAGGAGAGTGCCCCCATGGATCTCACTCTCACCAAGCCGCGTGGCCCGATGTCCGCCATCTCGCCATCGCCAGTTCATCATCCAGGAACTGCCATCCAAGAACTGCCCAAATCGCAGGCTCAGCAGATACACGACGTGATCTTTGGCAGTTCTGGCAACGCGAGTGGCTTCATGAAGACCCTGATCTCGGTGTCGGATAAGGTGCGCATCTCCGCCGAAATGGAGGAGCAGGCCAAGCACGAGGCCGAGGGCGAGGATGTCCAGCTKCAGACCTACATCAAGGAGCATGCTCTGCACCAGGCCAAGATAAAGCAGAGTCAcagcaacagaccCGTCATGAGCATAAACGAGGTGCCCAGCATTGAAGTGCATGAAGTTAAGACTCCGGAAGCCACAGAGCTGCCAACTATAGCTCCTGTCATCCCGCCAGTTACATCAACACCAAATCCTGTAAAGATTAGCCAGGAGGAAAGCGAGGAGAACGAAGCACAATCGGATCAKGAGAAGCCCAACATTGTGGAGCCGCATAATGCCAATCTGCCCGCTGCAGTGCAGCAACCGGATGCCAATGATTTCAGCGGAGTGCTGGGAAATCCACCGCCACCAGCTGTGGCTGTAAGTGTGCCTGCCACACCCACGCAGCGTACTGTGATTGTGGGCGAAGATGGCTTTAAGAACTCCACACCCAGCAGCAAGAGCAGTGAACTCCAGCATGTGTCCTACGGCAGGGGAGTGCCGCCAGCTCCCATTGCCAGCGATGCGCGACCCACGTGCACCATCTGCGCCAAGACCTTCCAGCGGCAACATCAGCTAACCCTGCACATGAACATCCATTACATGGAGCGTAAGTTCAAGTGCGAACCGTGCAGCATCTCCTTCCGGACACAGGGTCATCTGCAGAAGCACGAACGATCGGAGGCACACAAGAACAAGGTGATGATGACGTCGACGTTTGGCGTTCCAACCACCTCCAATCCGCGACCCTTCGAGTGCACCGACTGCAAGATTGCCTTCCGCATCCACGGCCATTTGGCCAAGCATCTGCGCTCCAAGACGCACGTTCAGAAGCTGGAGTGCCTGCAGAAGCTGCCATTTGGAACGTACGCCGAAATAGAGCGGGCTGGGATAAGTCTCACTGAGATCGACACAAGTGACTGCGAGAATTCCTTGATTTCCCTCAAGTTGCTGGCCCAGAAACTGCTGGAGAAGGATCCGAACAAGCTGAGTGGCTACACCACGCCCTCCGGCATGATGCAGTTGGCCCAAGATGCCACAGGTCCCGTCTCGCAGGATAGCGCTTCCGAAGATGGCTTCAGTGCGGCCATAGCCTCGGCCATAGCATCACTGGACAACGACAGTGCGGGGAATACCCCAAAAAGGGCCAGTTCCATGTCCGAAGACGAAACGGTGGCCAATGGCCTGAATCACAGTCTCAAGCGACGATTGCCGGGCAGTTTTAGCAGCACAGGCGAGGAGAGCGACAATCCACCAGAGGGTAGTNNNGGNNAAAAGCGGGCTCGATCTGGCCAGGATCTACCTGTTCCTGTGCNNGTTCCCGTTGNNNNNNCCGTTCCCGTTGCTGTTCCCGTTCCCGTGGCTGCTTCGGCGGCGGCCAGCAACTGA
Protein Sequence: MTLQQMAAVSSNQEPVAPANVVNTMSNISSQASVNATPTPATXXATANATDEASLGDWSNISRYLHKKFKRLASTTEVESSHSTTNGSXXAHDAIRTTSMSSNSSLSPPPPPMMMPLANGMPAVANPAGEKSGRYVCPYCNLLCAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARARGLEVPADADDGLSDQDAELSNSSSELPSRAGSPYDEPISSPTPSPSTLSAAKSAYLQQPPLPQHLQQLPLGSPAAGTLPPTTADNLHSATAQHRPSIDYKPYKPNTQMKMKHHINSHQIQLQMQQQQSLLAQQSLLAAMPVPPGSVYYLGGQPPYYNQDAAAAAIHQQALLVRANSQVSSVAXXAPATPTPNANLSSFASSSGGMQVNVAKVQEHISKLISQNEAIVENKEILLQKKYPKQLSRSRSFNNANSNSATQHGSSNTTALHANSSHNINAQMPERETKQLEPPNGLAKRNTYKPATVATTPVKQQQQLPPPPSPLPMQTMQYRQDPATPVPKVEQPAAAVHVMPLNLSAKPKPTLVTVPVSSLPISSVASTPASSANPSSSAKTAAPPAQVNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKLHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKSHMANSKNPLSLAKLAWSQLKTKRSTLIEALRFVDAPLPSPGPLLGKTPLVDYSRQSAPRKPQDAVVITKMHEDRQFALRDIEAQPAKRVKTSDQVVXXXASVTPSFNFSFNNNGVPELQSSKEERLRRFTSSGGSMIPISECPDMDNSPKMIRTPLLSGGSFQDVSVKANNXXXXXEAGPSSKERKLMALVSGSGLLGVSTGPQHFQFPPINSITAFNPLTLPPMSELKALSPFGGVQNLPSEFSRQPPTPAQRQALQWNSKETAKKAPFNFLRMADNVKTAEXEVRHFNLDSVMAGKQQELTLQPLHVETPNGSATEEVASSSSGSAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKQVMALYDSRQRMLGNGSSTAMAGLGKLSYNLVASQQTVCSTSTTTSSSAFYRGPVKTPPTVTVAALSEANVAAKANEEAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMXPDSEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRLKEHEAARGLLSLSMTPPIPQSVSPYPQXQDTPLPAASPANSIGSSGSLPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVASEESAPMDLTLTKPRGPMSAISPSPVHHPGTAIQELPKSQAQQIHDVIFGSSGNASGFMKTLISVSDKVRISAEMEEQAKHEAEGEDVQLQTYIKEHALHQAKIKQSHSNRPVMSINEVPSIEVHEVKTPEATELPTIAPVIPPVTSTPNPVKISQEESEENEAQSDXEKPNIVEPHNANLPAAVQQPDANDFSGVLGNPPPPAVAVSVPATPTQRTVIVGEDGFKNSTPSSKSSELQHVSYGRGVPPAPIASDARPTCTICAKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMMQLAQDATGPVSQDSASEDGFSAAIASAIASLDNDSAGNTPKRASSMSEDETVANGLNHSLKRRLPGSFSSTGEESDNPPEGSXGXKRARSGQDLPVPVXVPVXXXVPVAVPVPVAASAAASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -