Basic Information

Insect: Drosophila guanche
Gene Symbol: -
Assembly: GCA_900245975.1
Location: NW:2042967-2048404[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 2e-05 0.0012 18.7 0.1 1 23 138 161 138 161 0.96

2 13 0.0014 0.085 12.9 3.1 2 23 210 232 206 232 0.90

3 13 0.0063 0.37 10.9 0.8 1 23 315 338 315 338 0.93

4 13 0.097 5.7 7.2 3.8 2 23 387 409 386 409 0.95

5 13 0.0012 0.069 13.2 0.6 1 23 473 496 473 496 0.88

6 13 0.00057 0.034 14.2 3.3 2 23 547 569 547 569 0.96

7 13 0.00046 0.027 14.5 0.0 1 23 654 677 654 677 0.95

8 13 0.00057 0.034 14.2 0.2 1 23 734 757 734 757 0.93

9 13 0.00096 0.057 13.5 2.2 2 23 807 829 806 829 0.97

10 13 0.0027 0.16 12.0 3.8 1 23 923 945 923 946 0.94

11 13 0.044 2.6 8.3 1.5 1 21 998 1018 998 1019 0.95

12 13 1.5 86 3.4 0.1 2 23 1060 1084 1059 1084 0.74

13 13 1 60 3.9 2.2 1 22 1101 1124 1101 1125 0.62

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	2e-05	0.0012	18.7	0.1	1	23	138	161	138	161	0.96
2	13	0.0014	0.085	12.9	3.1	2	23	210	232	206	232	0.90
3	13	0.0063	0.37	10.9	0.8	1	23	315	338	315	338	0.93
4	13	0.097	5.7	7.2	3.8	2	23	387	409	386	409	0.95
5	13	0.0012	0.069	13.2	0.6	1	23	473	496	473	496	0.88
6	13	0.00057	0.034	14.2	3.3	2	23	547	569	547	569	0.96
7	13	0.00046	0.027	14.5	0.0	1	23	654	677	654	677	0.95
8	13	0.00057	0.034	14.2	0.2	1	23	734	757	734	757	0.93
9	13	0.00096	0.057	13.5	2.2	2	23	807	829	806	829	0.97
10	13	0.0027	0.16	12.0	3.8	1	23	923	945	923	946	0.94
11	13	0.044	2.6	8.3	1.5	1	21	998	1018	998	1019	0.95
12	13	1.5	86	3.4	0.1	2	23	1060	1084	1059	1084	0.74
13	13	1	60	3.9	2.2	1	22	1101	1124	1101	1125	0.62

Sequence Information

Coding Sequence: ATGGAAGGAATGGACCTTTGGACATCAATGTTCTCGGCAGACttggaggaggacgaggaggagatcgaccaatatgcaaatgagaaCGGCCTGGACAGCAATCTGGCCGGCGACAGTGATGACATTCTGCCTGAGgaagacgatgatgaggaagaggaggagggagaGGTAAGGCCTGGCAGTGgtaatggaaaaacaaaagagcccGATCTAGATGATGATACCATATTTGACTTCGATCTTGAGCCGATTGTAAGCATTGGCGAGTCACAGCCTTCTCCGCAGCTGGCGCTTACTGATCCACCTGAAACATCTGTGCGACTGTCGGGAGTGGTCACGCGGCCCACCACCTCGCAGATCAATGCAACCGATGCGAACGGGGTTCCCATCAACTATGAGCTGGGCGTCATCTACATCTGCCCAGCATGCGGGGAGGAATTCCGGCAGCAGGATCTCTGGAAACGTCACATGAACCAGATGCACCAGTTCAACACGCGCCGCGGCCTCAACTTCATGGCCATGGACAAGCTCTATCATCGGTGCCTGGAGTGCAATAAGCGCATCGCCATGCACAGCCGGGAGAACCTGCTGAAGCACAAGTTCACCCATTTGCCGTTTCGGTGCACCAAGTGCTACATCTGCAAAAGGGAGTACAAATACAGACAAGACCTCATGGTCCACCTGAGGATGGTCCATTGCGACGAAGTGGTGGCCATGATGCGGGAGGGCTTCAACTTGGCGGGGCGCAAGACGCGGGTAAGGGAACCACGCACAGAGCAAATGCAACGCAAGGACCCGTTTCCCGAGGAGGATGATGAGCGAAACGATATTCTCGAGCCGGAGATGATGGAGGGGGAGGCGCCGCAGAGGAGACGCAAAAAGCGCAACCAAGGAGGTCTCTCTGGCGATGGTAGTGCGGATCTTTGCGAGGACTACATCCATTACATGTGCCCCGATTGCGGCACTGAGTGTGACACCCACGCCCAGTGGAGTCAGCACATTGAGTTTGTCCACGACTACGTTAGCCGCAGGGGCCTCAACTTCATCAGCGTGGACATGCAGATGCAGTGCCTAGAATGCAAGAAAATTGTCATCCCCAACACGATTAAGACGCTGCGGGCCCACAAGTTTACGCATCTGCCGCAGCCCGAGTGGCTGCGCTGTAAACTGTGCTACAAGGGCTACAGGGAACACCACGAGCTAGTCACTCATCTGCTGAAGCAACACCAGCTGGAGTCGCTGATGCCGGAGGAGTCGCCGGATACATCGCCCGTGAAAAGGACAGATCGCGGTGGCGACGACTGGGAGGACCATGGAAACGCCAGCGCCTTCGATGACGTTTCGTCGCATTTTGAAGATGTTCCGCGAAGGGGAGGCCGCATCGGGAGCGATGACATCTACGAGCCACACATCGACTACCTGTGTCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAGCACTGGCGCACCCACGTGGTGCAGGTGCACGGCATGAACGATGTGACGAAGCTCAACTTTGCGATCATCAACGATCGGCAGTTGAAGTGCACGGAGTGCGCCAAGATCATAACGAACGCCTACGGCATACAGAACGCCCAGCAGCACAGGATTACGCACCTGCCATTCAAGGCGTACGCCAGGTGCCGCAAGTGCCACAAGTCCTACACGGATCGCAAGGGTCTGGTCAAGCATCTGGCCACCTACCATCGTGTAGGCTACGTGCCGCGCAAGAATTTCAAAATGGGCGGACGAGGGGTCCGGCTGTTTGAGTCGcccaagcagcagcgcaaACAGATTGTGACCCTGGGAAAGGAGACCTACGAGATCATCTTCCTTGACGAAGAGCAGGTTCACTCAAGTGTCGACGAGGAGAACGACTTTGGagagcagatgcagatgccgGATGAGGATGACTTGCCCACTGTCAGTGCGGGACTGCTGCCGCCCAATCCAAATCGCTACAAGTGCGTGGAATGCGGAACGTTGTTCCCCACCCAAGTGGCTCTCAAATTGCACATTAGCGAGGCACATGCGTTGCGGGATCCCCCTCCATACGCAGCACCGAAGAAGATGGAAAAAAACCTGGGGAAGGAGGATGCACTCAAGAAGAGGAGACTAGGATCAGCCGAAGCATtagtatcagcagcagcagcggccacaaGCGGCCCATCGGCGGGCACCGTGGAGGAGAACTACATATTCCTGTGCCCCTCGTGCGGCGAGGAGTACAAGACACAGTTTGAGTGGCGCCGCCACATCAACGAGGCCCACAACTTCGACAAGAGGCAGTATCTGAATATGCGGCAGCTGGACAAGTACCGCTACCAATGCACCCAGTGCAACGACATTGTGTGCAACTCCAAGTTGAAGGGCCTGCAGGACCACCACTTCCGGCATCTGCCCTTCCGCCTGTACCTCAAGTGCCTCGTGTGCGGCACTTGCTACAACCACAAGCCCAACATTGCCGCCCATCTGAGGACGCGGCACAACATCTACGAGCGGGAGACGCCCTGGCGGGAGCTACAGACCAAGCCGCAGTACTCGTATGTTCAGGCTAAGGAGAAGGACAGGGATACGGTCGCCAAGAGCAGGCAACCAAAGTCACCTGCACCATCGCCTGCAGTTGTCGCCTCATCCTCTGGCTCCAGCGTTGGCAGTCGCCTGCTCTGGACGCAGTCCGAGAAGCGGCCCACACGGCCGGCCGGACTAAACACCCTGGAGGACAGCATCTCGTACCACAATGCGGTGGACATGGACTTCATCACGTACTACTGCCCCAAGTGCAACAAGAACTTCGACTCGCACGCCTTCTGGCGCAAGCACATCGTGGAGCATCACAACTTTAACAGCCGCGAGGGGCTGAACTTCCGGCAGATTGACATCCACCATTACTTGTGCCTGGAGTGCTACAAGCGTGTCACCGTCACTCACACCAAGGGCGCCATCGGGCAGCTGCAGTCGCACAAGTTCCGCCATCTGCCCTACCGCTCCTTCAAGTGTCTCACCTGCAACGGAGAGTTTGTCCGCAAGCAGATGTTCTTCAAGCATCTGAATCGGGACACCAATCGGTGCGACAACAAGCCCAACGCCGAGAAGGAGTTTGACGACGAGGAGCACGAAACGTGTGGCGATGCCTCCACAGAAGATGCAGACGCAGAAGCATCTGCCTATCGACTGATGTGCCCCCAGTGCGGCGACGACTTCACCACCAGCAACCAGGGGATATTGCGCAATCACCTCAACGTCTCCCACGGCCTGGGCAAGCAGCTGCTACACATTCGAAAGGTGGGCGAGGGGCTCTACCGCTGCAACGACTGCGACGAAGAGTTGGCTACAAAAAGCAAGTGtgtcctgcagcagcaccgctTCAAGCATATGCCCCATGCCGCCTACATTATTTGCCAACTATGCAAGAGCGGGTCGGAGGAGAAGGCGGCTGAATTGCATAGCATGCGGGAGCTACATCAACACATCCACGAACACCATCCGGCAGTGGAAGTGTGTGACGAGCGGGTGCAGAGGTTGCGCCAACTAAtagacgaggaggaggaggccgacGAGGACAGTCAGCCACCAGAAAACAGCGGCAATGGATCTGGCTCGACGGCGAACAATGGTCCTTATATGCCGCTACCGCCACATTTACTGGATGAGGTGGACGATTTGGATTTTGAGGATCAGTTTCTGCTAGGAGGGTGTTAG
Protein Sequence: MEGMDLWTSMFSADLEEDEEEIDQYANENGLDSNLAGDSDDILPEEDDDEEEEEGEVRPGSGNGKTKEPDLDDDTIFDFDLEPIVSIGESQPSPQLALTDPPETSVRLSGVVTRPTTSQINATDANGVPINYELGVIYICPACGEEFRQQDLWKRHMNQMHQFNTRRGLNFMAMDKLYHRCLECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGFNLAGRKTRVREPRTEQMQRKDPFPEEDDERNDILEPEMMEGEAPQRRRKKRNQGGLSGDGSADLCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFISVDMQMQCLECKKIVIPNTIKTLRAHKFTHLPQPEWLRCKLCYKGYREHHELVTHLLKQHQLESLMPEESPDTSPVKRTDRGGDDWEDHGNASAFDDVSSHFEDVPRRGGRIGSDDIYEPHIDYLCPQCGKEFIEKKHWRTHVVQVHGMNDVTKLNFAIINDRQLKCTECAKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRVGYVPRKNFKMGGRGVRLFESPKQQRKQIVTLGKETYEIIFLDEEQVHSSVDEENDFGEQMQMPDEDDLPTVSAGLLPPNPNRYKCVECGTLFPTQVALKLHISEAHALRDPPPYAAPKKMEKNLGKEDALKKRRLGSAEALVSAAAAATSGPSAGTVEENYIFLCPSCGEEYKTQFEWRRHINEAHNFDKRQYLNMRQLDKYRYQCTQCNDIVCNSKLKGLQDHHFRHLPFRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERETPWRELQTKPQYSYVQAKEKDRDTVAKSRQPKSPAPSPAVVASSSGSSVGSRLLWTQSEKRPTRPAGLNTLEDSISYHNAVDMDFITYYCPKCNKNFDSHAFWRKHIVEHHNFNSREGLNFRQIDIHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPNAEKEFDDEEHETCGDASTEDADAEASAYRLMCPQCGDDFTTSNQGILRNHLNVSHGLGKQLLHIRKVGEGLYRCNDCDEELATKSKCVLQQHRFKHMPHAAYIICQLCKSGSEEKAAELHSMRELHQHIHEHHPAVEVCDERVQRLRQLIDEEEEADEDSQPPENSGNGSGSTANNGPYMPLPPHLLDEVDDLDFEDQFLLGGC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -