Basic Information

Insect: Drosophila guanche
Gene Symbol: -
Assembly: GCA_900245975.1
Location: NW:8135003-8139279[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.016 0.94 9.6 0.8 2 23 322 344 321 344 0.96

2 18 1.1 63 3.9 0.0 1 23 351 376 351 376 0.94

3 18 0.076 4.5 7.5 1.6 2 19 387 404 387 406 0.93

4 18 3 1.8e+02 2.4 0.5 3 23 449 470 448 470 0.92

5 18 0.015 0.91 9.7 0.2 3 23 478 498 476 498 0.92

6 18 0.053 3.1 8.0 2.1 1 23 506 529 506 529 0.95

7 18 0.0023 0.13 12.3 0.2 2 23 534 555 533 555 0.97

8 18 5.8 3.4e+02 1.6 0.0 1 20 563 582 563 584 0.91

9 18 2.2e-05 0.0013 18.6 0.6 1 22 603 624 603 627 0.91

10 18 0.73 43 4.4 0.2 3 21 634 652 634 653 0.90

11 18 0.015 0.89 9.7 0.5 1 23 672 697 672 697 0.95

12 18 0.67 39 4.5 1.9 2 23 715 737 714 737 0.94

13 18 0.0043 0.26 11.4 0.4 2 23 743 765 742 765 0.92

14 18 0.016 0.93 9.6 0.2 2 23 769 791 768 791 0.95

15 18 4.8e-05 0.0028 17.6 2.0 1 23 797 819 797 819 0.98

16 18 0.01 0.59 10.3 1.4 1 23 823 846 823 846 0.93

17 18 1.8e-05 0.001 18.9 2.1 1 23 852 875 852 875 0.97

18 18 0.0038 0.23 11.6 0.8 5 23 888 907 879 907 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.016	0.94	9.6	0.8	2	23	322	344	321	344	0.96
2	18	1.1	63	3.9	0.0	1	23	351	376	351	376	0.94
3	18	0.076	4.5	7.5	1.6	2	19	387	404	387	406	0.93
4	18	3	1.8e+02	2.4	0.5	3	23	449	470	448	470	0.92
5	18	0.015	0.91	9.7	0.2	3	23	478	498	476	498	0.92
6	18	0.053	3.1	8.0	2.1	1	23	506	529	506	529	0.95
7	18	0.0023	0.13	12.3	0.2	2	23	534	555	533	555	0.97
8	18	5.8	3.4e+02	1.6	0.0	1	20	563	582	563	584	0.91
9	18	2.2e-05	0.0013	18.6	0.6	1	22	603	624	603	627	0.91
10	18	0.73	43	4.4	0.2	3	21	634	652	634	653	0.90
11	18	0.015	0.89	9.7	0.5	1	23	672	697	672	697	0.95
12	18	0.67	39	4.5	1.9	2	23	715	737	714	737	0.94
13	18	0.0043	0.26	11.4	0.4	2	23	743	765	742	765	0.92
14	18	0.016	0.93	9.6	0.2	2	23	769	791	768	791	0.95
15	18	4.8e-05	0.0028	17.6	2.0	1	23	797	819	797	819	0.98
16	18	0.01	0.59	10.3	1.4	1	23	823	846	823	846	0.93
17	18	1.8e-05	0.001	18.9	2.1	1	23	852	875	852	875	0.97
18	18	0.0038	0.23	11.6	0.8	5	23	888	907	879	907	0.85

Sequence Information

Coding Sequence: ATGTCGGAACACGCAAAAGCAAGCGCCAGCGTTCCTAGCTGCCTGCATTGTAGCGCATACGGttcgaaattgaaattccaaGATATATTCGATGAATTTGGCCTGGAACTGggactccagcagctgctggcgaaGCACTTCGACTTGGCTGTGACGCCCAacgaaaagcagcaacagatccTTTGCGCAGAGTGCGTCAATGTTCTCATCCGGTTATTTGACATTGACGAggtacagcaacagcaagatgCCGCGATTGCCAAGCGAGAGAACGCTGCTTCTCCGGCAGCAAAGAGTGCAGCCAAGATGCCACCAAAACCGTCAAAGCACACAACGCCGCCCAAGCCGCAAGTTAAAGTGGAAAAGCCGCCTGTGCCGGCGATCCAATTGCGGGAGCCCAGTCGGCGTATAATCAAAAATAACGCAGCAGTCGTTGTGGATAAAGTTGCGGCACCAGCCAGAACTATCGTGCAGGTTTCTCCGCCCATTGCAAGAGCTCCGAAGGACGCCGACCAGGAGCAGATTAGTGCCCTCATTCTCAATATTCTAAACGAGGATGAGCCGGGCGAGGAAGAAGATATTGATGCCGATAATGTGGCGTCCGTCTCACCCCAAAGATCGGCAGCAATCACAAGTCGAACAACAATTGATGAGCCAGAGGAGGAAACGGTGACCGAGACAGTGACTGAAGACGATCTAGATGGAGTGCACATAATATACGAGCATGACGATATTTCATTGGAAGAGGAGGTAAATACCAAGCCAGACATCAGTGAATGCAGACTGAAAGTGCTGAAAAGGGATAGCCAGAGCGAAGCTGAGAACGAGGAGGGCGAGATCAGCAATATTATTGTCTTTAACTTTGTCGACATCAAAGAAAAGGATGATATTGAGGATCTATACGAGTACTTGGGCACGGTGGTGAAGACCAGTTTCCATAAGCTAACCTTTGACTGGAGCACAGTCTGCAAGCTGTGCAAATTCAAGTCCGCTACGTTCGAGAATCTGCTGGAGCACATGCAGAAGGTGCACAAGTCTCGGACGGATGTGTTTCAGTGCCCCATCGAAGGCTGCAGCATGGAGCTTAAGGGAAACAAACTGCTGGCCATGCATTTGGTGGTTCTACACGCACCAGTGGCTGATATTGCCATTTATGGCAGCTGCCCGGAGTGCAAGATGACATTTTCGAATATTTTGCAGTACAACAAACACTCGTGCGCACGTTTCATCAAAAAGAGACGAGGCGTTCGCTTGTATTGCGAAATGTGCGCCTTGGAGTTTCCCTCCTGGAAGCGTTTCAATTTTCACAATCAATTCCATTTGGAGAAGCACCGACCGCGTGCATGCTTCGTCTGTGGCTATGAGAACACCAACATCGACGAACTCTTTCAGCATTTGCACTATTCCCATGAGCCAGAGGGCACACTCTTCTGTGATCTCTGCGATCGCACGTTCCGGAATGCTGCTGTCTTTGCCGAGCACAGCTCATCGCATGCGAATGTGAGCAACACCACCCACTGCTGCAGCGAGTGCATGGCCACCTTCGAGACTCGTGGCAAACTGAATGTCCATGTGAGATTAATACACGGCAAAGTCATCAGCTGCGAGCTGTGCTTCCGTGAATTTGCCTCTGAGGTTACCTACAATGTGCACATGAAATCCCATTTGATTATCGAACGTGATCTTCACGTCTGCGTCAGTTGTGGCCAACTCAGTGAGAATCAAGAGAAAATGAACGCCCATCTGGCAGTCGAGGATTCGGCCTGCTATGGCGCAGAGAGTTGCGTGGAGCTGGTTCGCGATGCGTATGTCTGTGAGTACTGCACGACGTACTTTAAGCAAAAGTCCGATCTGCAGGCGCATCGCGAGTCCGGTGTGCACGACAATGGTGTGTTTTGGTGTCAGCCTTGCAAAAAGGAATTTCCCGACATAAAGTTGTATCGCAATCATTTGCGCAACTTCCAGGCACTGCGCACAGATGTGGCACATCGCAAGCTGGACATTTGCAGCTTCTTCATGTGCGATCAGAAGGGTTGCTCGGCGGTATATGCCAACTGGAACTCTTTGTACACCCACAAGCGACGCACTCACGATGCGCctgagaagcagcaggagaaatCGGGCAAGCTGTTGCAggaatggcaatgccaattcTGTCTCAAGTTATGCCGCTCCAAGATGTCCTTATCCGTGCATGTCGCCCGTAGCCATAATAATGACAACGTGGTCTGTTCGCTGTGCAAAGCGTCGTACAAGAGCAAGGAGGCGCTGGAGAACCATCATGCCTACTGGCACGAGCCCATCGAGTGTCCGCAGTGCTTCAAGATAGTCAAGAATCGCCGCAACTACGACACCCACGTGAATGTGGTGCACTCCAACAAAAAGCGCTACACTTGCAGTGTGTGCGAGAAGGGCTTCTACCACAAGAGCGAGATGGAGGCTCACAAGAGGCTACATTCGCAGTCGTACAGCTGCGATCAGTGCAGCTTCACCACCAGGAACAAGAAATCACTGTCTGTTCACACGCTGGGCCAGCACTTTAAGCGTTTCGCCTTCGAATGCAAGATGTGCGACAAGCACTTTGGTCGACGCCAGGGACTGACCAATCACATACAGCGTGTGCACGCCTCCAAGCATGTGTGCCGCAACTACATTGATGACGGCTGCGGACGTTCGTTTAACACCAGTTTACAGGTGAAGATGCATTTGCGCAAGGTGCACAACTCCACTTTGGTGTCTGACGATGTGCTCGAAGAAGAGGCGTATGCCAACGCCAGACCCAGGCCAGCGAAGAGGCGTTGCCTTGGATTGGGGCAAGATACCAAAGACGACAGTGCGGATGATTTGGATAGAATGAAAGACGCTGATTATCAACCAGAGGAAGGAGACGAGGAGGAtgtggcggaggaggagcaggaccaggagGAAGAATGTGAGCTGGAGTTTTCCGTAgacgaggcagaggcggagcataaaccgaaaccaaacTCTGGCTCGCTCACAGTCAGACATGGAAgaaaaaattgttcaaattaG
Protein Sequence: MSEHAKASASVPSCLHCSAYGSKLKFQDIFDEFGLELGLQQLLAKHFDLAVTPNEKQQQILCAECVNVLIRLFDIDEVQQQQDAAIAKRENAASPAAKSAAKMPPKPSKHTTPPKPQVKVEKPPVPAIQLREPSRRIIKNNAAVVVDKVAAPARTIVQVSPPIARAPKDADQEQISALILNILNEDEPGEEEDIDADNVASVSPQRSAAITSRTTIDEPEEETVTETVTEDDLDGVHIIYEHDDISLEEEVNTKPDISECRLKVLKRDSQSEAENEEGEISNIIVFNFVDIKEKDDIEDLYEYLGTVVKTSFHKLTFDWSTVCKLCKFKSATFENLLEHMQKVHKSRTDVFQCPIEGCSMELKGNKLLAMHLVVLHAPVADIAIYGSCPECKMTFSNILQYNKHSCARFIKKRRGVRLYCEMCALEFPSWKRFNFHNQFHLEKHRPRACFVCGYENTNIDELFQHLHYSHEPEGTLFCDLCDRTFRNAAVFAEHSSSHANVSNTTHCCSECMATFETRGKLNVHVRLIHGKVISCELCFREFASEVTYNVHMKSHLIIERDLHVCVSCGQLSENQEKMNAHLAVEDSACYGAESCVELVRDAYVCEYCTTYFKQKSDLQAHRESGVHDNGVFWCQPCKKEFPDIKLYRNHLRNFQALRTDVAHRKLDICSFFMCDQKGCSAVYANWNSLYTHKRRTHDAPEKQQEKSGKLLQEWQCQFCLKLCRSKMSLSVHVARSHNNDNVVCSLCKASYKSKEALENHHAYWHEPIECPQCFKIVKNRRNYDTHVNVVHSNKKRYTCSVCEKGFYHKSEMEAHKRLHSQSYSCDQCSFTTRNKKSLSVHTLGQHFKRFAFECKMCDKHFGRRQGLTNHIQRVHASKHVCRNYIDDGCGRSFNTSLQVKMHLRKVHNSTLVSDDVLEEEAYANARPRPAKRRCLGLGQDTKDDSADDLDRMKDADYQPEEGDEEDVAEEEQDQEEECELEFSVDEAEAEHKPKPNSGSLTVRHGRKNCSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00601268;
90% Identity: iTF_00601268;
80% Identity: -