Basic Information

Insect: Drosophila guanche
Gene Symbol: pita
Assembly: GCA_900245975.1
Location: NW:2171465-2176815[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 5.8 3.4e+02 1.6 0.2 1 14 64 77 64 81 0.84

2 11 0.00043 0.025 14.6 0.1 1 23 303 325 303 325 0.97

3 11 1.5e-05 0.00087 19.2 1.9 1 23 331 353 331 353 0.97

4 11 4.5e-06 0.00027 20.8 1.4 1 23 359 381 359 381 0.97

5 11 0.02 1.2 9.3 0.9 1 23 387 409 387 409 0.96

6 11 8.1e-05 0.0048 16.8 0.7 1 23 415 437 415 437 0.95

7 11 3e-06 0.00018 21.4 0.5 1 23 443 465 443 465 0.94

8 11 4.5e-05 0.0026 17.7 5.4 1 23 471 493 471 493 0.98

9 11 3.5 2.1e+02 2.3 0.7 1 20 501 520 501 523 0.83

10 11 0.83 49 4.2 0.1 2 23 529 550 528 550 0.93

11 11 0.072 4.3 7.6 0.1 1 23 556 579 556 579 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	5.8	3.4e+02	1.6	0.2	1	14	64	77	64	81	0.84
2	11	0.00043	0.025	14.6	0.1	1	23	303	325	303	325	0.97
3	11	1.5e-05	0.00087	19.2	1.9	1	23	331	353	331	353	0.97
4	11	4.5e-06	0.00027	20.8	1.4	1	23	359	381	359	381	0.97
5	11	0.02	1.2	9.3	0.9	1	23	387	409	387	409	0.96
6	11	8.1e-05	0.0048	16.8	0.7	1	23	415	437	415	437	0.95
7	11	3e-06	0.00018	21.4	0.5	1	23	443	465	443	465	0.94
8	11	4.5e-05	0.0026	17.7	5.4	1	23	471	493	471	493	0.98
9	11	3.5	2.1e+02	2.3	0.7	1	20	501	520	501	523	0.83
10	11	0.83	49	4.2	0.1	2	23	529	550	528	550	0.93
11	11	0.072	4.3	7.6	0.1	1	23	556	579	556	579	0.92

Sequence Information

Coding Sequence: ATGGAAGACCTCGCCAGAGCCCGTGAGTGCGAGTTGGCCGAGAAGAAAATCTGCCGCTTCTGCTTGACTGGGGAGAAAATAGCCTCGCTTTTTGCTGAAAACTCTAGTGTCAAGTCGACTGCATCGCTACCACTGCTGATAATGGCTCTCACATCCACCGAGGTGAGCGCCGATGATAAAATGCCCAGCTACATTTGCCTCGACTGCCATCTGCTGTTCGAGCACAGCTACCGCTTTATGCAGATGTGCAAGCGTGCAGAGACAGCGCTACGGCAATATCCGCTGACTGGAACGCTGCCAGCACCGATGGAGAAACCACGTCCACCTTCCAAGAATCCGACTGTGGTCGCTGCTGTGGTCAGGAAGGATGGCAAAGCGGCCGACGCACAGCCCAGGAAACTGCTCAACACGCTGGCCAACTCCAAGACGGTGATCATTGAGGATGTGCAGGTGCTGGAGACGAgtttgctggccaaaaaacTGGCCACAGCGTCCACACGCTCCAAATCCTATCAGATGAAGGTGGAGAACAATCAGGAGCTGTCCATGGATGACATACAGAACATGATGGATGATATGGACAACGAAGTTGAAGAggaagcagcagagacagcagcagcagcagcagcagcagcagcatcatctgtggcagctgcaacgTCGCCCCCAGCAGCTGTGCCGCCCGTTCAGCAGAAATTGCCCATCAAGCCAAAGGTGCTGAACAAACCCACCGTGCGGATACTAAACAAAGGCGCTGCAGTGGCCGTGGAGCCCGAACTGGCCACGAAACAGATCAAACGTGGACGGGATGGCAATGTGGCAATTGTCACGGAAATTATAGGCCCCAATACGGTGCCCCAACATGAGGATGCCACCAAGGACGCTGCCATCGTGGCGACCAATGTGTTTCCCTGCCCGGACTGCGAGCGCTCCtttccgctgctgcagctgctcgagaTTCATCGACTGAATCATACGCGCGCACGCAGCTTCCAGTGCGCCGACTGCAGCAAGGCGTTCTTCTCCAAGTACGATCTGCAGAAGCATCGATTCATACACACCGGCGAGAAGCCGTTCGCCTGCAGTGTCTGCGACAAGGCGTTCACGCGGCGAGCGCTGCTCCATCGGCACGAGAGCACGCACACGGATCTGCCGAAGTTCATATGCGTGCACTGCGAGAAGCCATTCCTGTCGCGCGAGGACATGACGAAGCATGCCGAAAGGCACACAAAGTCCCGACCATTCCGCTGCACCATGTGCAGCAAGTCGTTTGCCTTCAAGCAGGGCCTGGAGCGACATGAGGTGGTCCACAGCGTGAATCTGCCCTTCCCCTGCGAGCACTGCCCCCGGAGCTTTGTCACCTCCAGCAAACTGGCGCGCCATTTGGTGGCCCATGCGGGCAAGCGGGCCTATCCCTGCAAATACTGCTCCAAGTCGTACATTCTCTCGCATCATTTGTCGCGGCATTTGCGCATGCACAAGCAGGATTCGGGCGCCTCGTTTGCCTGCAGCATTTGCAAGGAGTCGCACCAGAGCTACGACAGTCTCATCGAGCACTCGGTGCAGCACGCGAACATGTCCCTCAAGTGTCCGCTGTGCAACGAGAAGATCCACGACATAGCCGCCGTGGAGGGACACATGACGACGCACAAGGAGGGCGAACGCTTTGCCTGCGAGTTCTGTGACTTGATCTTCCTCAGCTCGGAACGCCTGCAGAAACACATCGAGGATGAGCATGTgctggacatggacatgtaTCAGAACGATGGGGACAGATTCTCGAACCAGAGCGATGCCGAGGCAGAGTTTGACGCACATGAAGCCGAGATGGACGAAGCAGAGCAAAAGTTTCTGCTGCAGGAACTGCTGCGCGATGAGCAGCCAGcatcgccaccgccgccggtCAAGAAGCGCAAAGTGGAGGCCACGGACGCCTTTGTGATACCCAAACGCACACGGCAGACGCATCTGGCAGATGTCGCACCAGCAGAGACTTCCCCTACGACgagacagcaagcagtggCAACGAGGAAGGGATCGAGACGTTCGCTgattaaaaatggaaattcagCCACAAATTCCAGGCATTAA
Protein Sequence: MEDLARARECELAEKKICRFCLTGEKIASLFAENSSVKSTASLPLLIMALTSTEVSADDKMPSYICLDCHLLFEHSYRFMQMCKRAETALRQYPLTGTLPAPMEKPRPPSKNPTVVAAVVRKDGKAADAQPRKLLNTLANSKTVIIEDVQVLETSLLAKKLATASTRSKSYQMKVENNQELSMDDIQNMMDDMDNEVEEEAAETAAAAAAAAASSVAAATSPPAAVPPVQQKLPIKPKVLNKPTVRILNKGAAVAVEPELATKQIKRGRDGNVAIVTEIIGPNTVPQHEDATKDAAIVATNVFPCPDCERSFPLLQLLEIHRLNHTRARSFQCADCSKAFFSKYDLQKHRFIHTGEKPFACSVCDKAFTRRALLHRHESTHTDLPKFICVHCEKPFLSREDMTKHAERHTKSRPFRCTMCSKSFAFKQGLERHEVVHSVNLPFPCEHCPRSFVTSSKLARHLVAHAGKRAYPCKYCSKSYILSHHLSRHLRMHKQDSGASFACSICKESHQSYDSLIEHSVQHANMSLKCPLCNEKIHDIAAVEGHMTTHKEGERFACEFCDLIFLSSERLQKHIEDEHVLDMDMYQNDGDRFSNQSDAEAEFDAHEAEMDEAEQKFLLQELLRDEQPASPPPPVKKRKVEATDAFVIPKRTRQTHLADVAPAETSPTTRQQAVATRKGSRRSLIKNGNSATNSRH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -