Basic Information

Insect: Drosophila guanche
Gene Symbol: Znf526
Assembly: GCA_900245975.1
Location: NW:74519-79259[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00021 0.013 15.5 0.7 3 23 114 134 112 134 0.97

2 7 4.3e-08 2.6e-06 27.1 1.3 1 23 148 170 148 170 0.99

3 7 1.8e-08 1.1e-06 28.3 0.4 1 23 176 199 176 199 0.99

4 7 8.3e-05 0.0049 16.8 2.7 1 23 205 229 205 229 0.97

5 7 6.8e-07 4e-05 23.4 0.9 3 23 237 257 235 257 0.96

6 7 0.00012 0.0072 16.3 5.1 1 23 263 285 263 285 0.97

7 7 5.8e-06 0.00034 20.4 1.1 1 21 291 311 291 315 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00021	0.013	15.5	0.7	3	23	114	134	112	134	0.97
2	7	4.3e-08	2.6e-06	27.1	1.3	1	23	148	170	148	170	0.99
3	7	1.8e-08	1.1e-06	28.3	0.4	1	23	176	199	176	199	0.99
4	7	8.3e-05	0.0049	16.8	2.7	1	23	205	229	205	229	0.97
5	7	6.8e-07	4e-05	23.4	0.9	3	23	237	257	235	257	0.96
6	7	0.00012	0.0072	16.3	5.1	1	23	263	285	263	285	0.97
7	7	5.8e-06	0.00034	20.4	1.1	1	21	291	311	291	315	0.92

Sequence Information

Coding Sequence: ATGTGGCAACGCTTATGGCGACgcgaaaaaaaactaaatttttACTTGTTGGAGCCCCGGAAAAAAGAAATGGCGATTCAAACGCTGGAGGAGGCCGACATCGACTGGGATTCACTTATCGAAGAGTGCGAGGAGTCCGAAGAGTCCGACGAAGAGTGGGTCAACTCGATAATAGTAGAAGAACCCGAAGAGGAGCTGGCAGCAATGATGGTGGATCAGGACGAAGCAGAAGATGACCCTGGAGACTGGATAATACAGCAGGAGGCGGAAGAGGAGGAATTAGAGCCCGGAGAGTGTAGACCAGGTCCATGCCATGCAGCGTTTCGCGTGCCCTGGGCCTGCACACGCTGCCCCCTGCGCTTCGTCAGCCACGAGAAGCTCATCGCCCACCGGCGCATGCATCCCCGAACGCGCAGGGACAACCGACCGCCAGCGTCCATCTTCACGTGCAATGAGTGTGGCAAGGAGTTCAAACGCCGCCGCTGGCTCGACGAGCATATGCGCACCCACACGGGCGACCGGCCGTACAAGTGCTCCGATTGCGGGGCCCGTTTCGCTCAGAACAGCAACCTTAGTGTCCATATTCGAACGAAGCACCTCAAGGAGGCCCTGCACCAGTGCCCCAAGTGCCCCGATCGCCGATTCACCCGCCGACGtctgctccagcagcacctCAAGACGGTGCACCTGAAGCTGTTCGATCTAGCCTGCGAGCAGTGCGGCGCCAGCTTCTCGCACCAAACCTACCTCAAGAAGCACATGCTGGTCCATGGCTGTAACAAAGCCTACAGCTGTCACATATGTGGCAAACAGTTCTGCCGGCTAGAAAACCGAAACTCTCACCTCTTTGTCCACAGCACGCGCAAGCCCTACATCTGCACTGTGTGCGGCACAGGCTTCTCGAGAAAAGCGCATCTGCTGCAGCACATTCAGTTCAAGAACCACCCCAACGAGGTGATCCAGCGGCAAAAGCCCCACTTTAGCGACATGCTCAACCAGTTCACCCGCAAGGAGATTGGTGGAGCAGTTCAgttcaattga
Protein Sequence: MWQRLWRREKKLNFYLLEPRKKEMAIQTLEEADIDWDSLIEECEESEESDEEWVNSIIVEEPEEELAAMMVDQDEAEDDPGDWIIQQEAEEEELEPGECRPGPCHAAFRVPWACTRCPLRFVSHEKLIAHRRMHPRTRRDNRPPASIFTCNECGKEFKRRRWLDEHMRTHTGDRPYKCSDCGARFAQNSNLSVHIRTKHLKEALHQCPKCPDRRFTRRRLLQQHLKTVHLKLFDLACEQCGASFSHQTYLKKHMLVHGCNKAYSCHICGKQFCRLENRNSHLFVHSTRKPYICTVCGTGFSRKAHLLQHIQFKNHPNEVIQRQKPHFSDMLNQFTRKEIGGAVQFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00601209;
90% Identity: iTF_00601209;
80% Identity: -