Dgua011729.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila guanche
Gene Symbol
kipf
Assembly
GCA_900245975.1
Location
NW:2854330-2857381[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 2.4e-05 0.0014 18.5 4.3 1 23 217 239 217 239 0.97
2 16 0.047 2.8 8.1 1.3 1 19 288 306 288 309 0.86
3 16 0.006 0.35 11.0 2.9 1 21 312 332 312 333 0.95
4 16 0.0013 0.074 13.1 2.8 1 23 340 362 340 363 0.94
5 16 0.52 31 4.9 0.8 1 19 370 388 370 392 0.91
6 16 0.00057 0.034 14.2 5.4 1 21 534 554 534 556 0.94
7 16 4.1e-06 0.00024 20.9 1.7 1 23 568 590 568 590 0.98
8 16 0.00016 0.0093 15.9 0.9 1 23 596 618 596 618 0.96
9 16 6.6e-07 3.9e-05 23.4 3.2 1 23 624 646 624 646 0.98
10 16 0.0043 0.25 11.4 0.8 3 23 654 674 652 674 0.96
11 16 6.9e-06 0.00041 20.2 0.2 1 23 680 702 680 702 0.98
12 16 6.2e-07 3.7e-05 23.5 1.3 3 23 710 730 708 730 0.97
13 16 0.0021 0.13 12.4 1.3 1 23 736 759 736 759 0.95
14 16 2.1e-05 0.0012 18.7 4.5 1 23 764 786 764 786 0.98
15 16 0.021 1.3 9.2 2.4 2 21 793 812 792 812 0.95
16 16 0.0061 0.36 10.9 1.9 2 23 819 841 819 841 0.94

Sequence Information

Coding Sequence
ATGGAGAATATGTGCAGAGTGTGTCTGGATGGCTCAGTGACACTGGTCGACATATTTGCGGCGATACGCAATCCAAAAAGTGGACCCGAATTTGGAAAAAATCCCGCTGACCTGCTGAGCCAGTGCTCGCCCACTTATTCTGTGGTGCGTGGCGACGATATGCCGCAGTTTATATGCCTCTCCTGCATTGACGCCGCCCAAAACGCATATCGTTTCCTTCTAAAACTGAAGCAAAGCAAGGCCAAGTATCGTCATCTTAATTtaaagaaattgaaatgcgTGGCTCCAACCAAAAGTAGTGTGGAAAATGTGTCGGAGCTCTCAATAGATGGCCATGATATTCAGATAATTAAGCAAATACCAGAGCTGGCTCAGGTGCCAGAAGCGAATTTTCAAAATCTAATATTAGAGGAGGATCACATACCAAATAATTTAGAACCGGAAAAATCACAGGAGCCTTGTTTCAAAGAGAGTTCTCCGGGTTTGATGGATCTACTAATGAGTTTGTCATCAGACTCTGAGAAGGGGGAAAGCGATACCGAGGCACCGAAGCTGACCACATTAATTGGGTGCAGGTGGTGCGGAAAGAAAATCTCGCGAGATCAGGTTCAGTTTCATGAATTGTGTTCCTGTCCCAAGCTTCCGGCGTTCGCCTGTAATATTTGTGGCCAGGGATTCAGGACTGAATACCACCTAAAtaaacacacgcacaggcaCAATATCAAGCAGACGTCGAAAAGAAGCAATGGAAAGCCTCCTGAAGGTACAATTTCGAGTTCACCCAAAAATAAGCAACCAGAAGACCACACAAATGATCGTGAGAGGAGCATTTCTCCCAGAAAAGGTCGTAGCACTGAAGAATTTCTATGTCTGGAATGCCATAAGACTTTTGACTCCAAGGAAAAGCTGACATTTCACAGGGATATGATGTGCCATAAATGTCCCCATTGCTCACGCTTTTTGACAAGCGATCGCAGTCTTAAGAGACATCTCAAGGAGAACTGTACAGTGGCAGTCTTTGACTGCCGTCGTTGCCCACGCAAATTCATGCTAAAAGATAACTTGCTGGCGCACCAGAAATCTCACCATAACGATAGCGATGGAACTTTCAATTGCATGAAATGCCATGCAGAATTCAATGATATCGTTTATCTGCGGATCCACGATAAAGAGCACTATCCAGATCAAGGGCAAGTTAAGCATAGCCAAGGAGTTACAGGAGCCTTGCAACTAAAGCATAGCCAAGGAGATACAGGAGCTGATCTGCATAGTAACAGGAAACGTCACATATCGGATCAAGGTCAAGAAAATGGTCAACTGAAGTGTAGCGAAGAAGTTACAGGAGCTACTACCCGTAGTGCCGGGAAACGGAGGTTTAGCCAAGAAGATGCAGGAGTTTCTTCCCGTCGCTTAAGGACTCCATCACTGCTGAAGCGGATGCAGAGCTGCGACGACACGGACACTGACACCGACACATCAAGCGATACCGTGAGCCCATCCTTGGCAAAAGAAGCGAGTTTTCCCTGCGAGGATTTTTTTGGTAAGAAGTTTGCGACAAATGCTATCCTGCATAATCACAATCGTTTGCACGCTCGTCCCTACAAGTGCGAGCGCTGCACGAAGAAGTTTTCTCGCAAAAGTCAACTGGTTGAGCACAGTCGTTGTCACACGGGCGAACGTCCGTTCAAACACAAGCGTTCCTACAAGTGCTCGGACTGCGGCAAAACATTTGAGAAACAGCAAAGCTTTTTTAGGCACGCTCTTGTTCACACGTTCGAACGTCCCTACTTATGCTTGATTTGCAACTCGCAATTTAAGCGAGAGGCTTCGCTGAAGAGACACGCTCGTACGCACACTGGCGACCGACCGTTCGAGTGCCCGTATTGCGACAAGAAATTTACGCGCAATGAATGTCTGCAAATACACAAGCGCATTCACACGGGCGAACGTCCCTTTGGGTGTACGCAGTGCGACAAAAAATATTATCAAAAGACAAAGCTGGATGAACATATTCTAGATCACACTGGCCAACGTCCCTACGAGTGCTTGATTTGCCAAAAGGTATTCAAGGGTAAAGCTGCTCTGAACAGACATGCTCTTACGCATGCCGCCAAACGTCCTTACGGGTGCTCCGATTGCGACAGGAAATTTACATCCAATTCAAACCTGAAGAGGCACACTCTTATTCACACTGAGGCACGTCGTTTCAAATGCCCTCACTGCGACAATGAATTTCAGGTCAAGCGAGACCTTGATAAGCACTTATTTGTTGTTCACGAAATAAGTGTTTACgagtgcaagcagtgcaacACGAAATATGTTCGCAGAAGCGACCTGACCAGGCACCATCGTCTGCACAATAGCGAGAATTATTTAAAGTGCGAGGATTGCGGCACACATTTTCAGAGCCGTTGTGACATGATTAACCACACTCGCTGCGATAAAGGACCCAACACCTGCTTGCAATGCGGCATACAATTTAAGCAAAGCTGTTTGCTGAATCAGCATGTTGCTCGTACTCACAGTACTCACGAAAGTCTTCCCGAGATGAAATTCAGTGCGAGTACGGATCTTGAGAAACATAAGCTCAAAAGAGCGGCGTCTGACAAGTCAAGCTTTACCAAAGTTAATAAGCCGGAAAAGCGTTTGGTCGTACGTTTGACTCGTGCAAAATTGCCAATGAActtataa
Protein Sequence
MENMCRVCLDGSVTLVDIFAAIRNPKSGPEFGKNPADLLSQCSPTYSVVRGDDMPQFICLSCIDAAQNAYRFLLKLKQSKAKYRHLNLKKLKCVAPTKSSVENVSELSIDGHDIQIIKQIPELAQVPEANFQNLILEEDHIPNNLEPEKSQEPCFKESSPGLMDLLMSLSSDSEKGESDTEAPKLTTLIGCRWCGKKISRDQVQFHELCSCPKLPAFACNICGQGFRTEYHLNKHTHRHNIKQTSKRSNGKPPEGTISSSPKNKQPEDHTNDRERSISPRKGRSTEEFLCLECHKTFDSKEKLTFHRDMMCHKCPHCSRFLTSDRSLKRHLKENCTVAVFDCRRCPRKFMLKDNLLAHQKSHHNDSDGTFNCMKCHAEFNDIVYLRIHDKEHYPDQGQVKHSQGVTGALQLKHSQGDTGADLHSNRKRHISDQGQENGQLKCSEEVTGATTRSAGKRRFSQEDAGVSSRRLRTPSLLKRMQSCDDTDTDTDTSSDTVSPSLAKEASFPCEDFFGKKFATNAILHNHNRLHARPYKCERCTKKFSRKSQLVEHSRCHTGERPFKHKRSYKCSDCGKTFEKQQSFFRHALVHTFERPYLCLICNSQFKREASLKRHARTHTGDRPFECPYCDKKFTRNECLQIHKRIHTGERPFGCTQCDKKYYQKTKLDEHILDHTGQRPYECLICQKVFKGKAALNRHALTHAAKRPYGCSDCDRKFTSNSNLKRHTLIHTEARRFKCPHCDNEFQVKRDLDKHLFVVHEISVYECKQCNTKYVRRSDLTRHHRLHNSENYLKCEDCGTHFQSRCDMINHTRCDKGPNTCLQCGIQFKQSCLLNQHVARTHSTHESLPEMKFSASTDLEKHKLKRAASDKSSFTKVNKPEKRLVVRLTRAKLPMNL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00601191;
90% Identity
-
80% Identity
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