Basic Information

Insect: Drosophila guanche
Gene Symbol: -
Assembly: GCA_900245975.1
Location: NW:4983139-4986800[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00016 0.0094 15.9 0.2 1 23 190 212 190 212 0.95

2 11 3.8e-05 0.0022 17.9 1.5 3 23 222 242 220 242 0.96

3 11 5.5e-06 0.00033 20.5 3.1 1 23 248 270 248 270 0.99

4 11 1.2e-05 0.0007 19.5 1.8 1 23 276 298 276 298 0.98

5 11 7.1e-07 4.2e-05 23.3 0.7 1 23 304 326 304 326 0.98

6 11 4.8e-07 2.9e-05 23.8 1.3 1 23 332 354 332 354 0.98

7 11 3.9e-08 2.3e-06 27.3 1.4 1 23 360 382 360 382 0.99

8 11 1.8e-05 0.001 18.9 7.7 1 23 388 410 388 410 0.99

9 11 5.7e-07 3.4e-05 23.6 0.3 1 23 416 438 416 438 0.98

10 11 2.5e-06 0.00015 21.6 0.7 1 23 446 468 446 468 0.98

11 11 3.4e-05 0.002 18.0 0.1 1 23 484 506 484 506 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00016	0.0094	15.9	0.2	1	23	190	212	190	212	0.95
2	11	3.8e-05	0.0022	17.9	1.5	3	23	222	242	220	242	0.96
3	11	5.5e-06	0.00033	20.5	3.1	1	23	248	270	248	270	0.99
4	11	1.2e-05	0.0007	19.5	1.8	1	23	276	298	276	298	0.98
5	11	7.1e-07	4.2e-05	23.3	0.7	1	23	304	326	304	326	0.98
6	11	4.8e-07	2.9e-05	23.8	1.3	1	23	332	354	332	354	0.98
7	11	3.9e-08	2.3e-06	27.3	1.4	1	23	360	382	360	382	0.99
8	11	1.8e-05	0.001	18.9	7.7	1	23	388	410	388	410	0.99
9	11	5.7e-07	3.4e-05	23.6	0.3	1	23	416	438	416	438	0.98
10	11	2.5e-06	0.00015	21.6	0.7	1	23	446	468	446	468	0.98
11	11	3.4e-05	0.002	18.0	0.1	1	23	484	506	484	506	0.96

Sequence Information

Coding Sequence: ATGAAAACTCCCACAAATTCCAGCATTTTGCAGCAATGTCGCTTCTGCAGGAAAACCTCGGTAGCATCGGTGGACATCTTTTGCAAGGGGACAACGGATTCCAGCATTTCGGAAATGGTGAACGGTCTTTTAAGCGAGAACTGCCAGGTTAAACGGGATGCACTGCCGCAGTGTGCCTGCCTGGCCTGCATACTGGCCACCAAAAGTGCCTTTAGCTTCAAGAGAAAGTGTGAGGAGAGCCATCGATTCTTTTCTGAGCTTCTGCTGATAAAGAGCCCCACTCACCTTGGAGGAAACAAGCTTGCCGATGAGGATGAAAGCGACGAAGATGAAAGGCTACCCAGTGAGATACCTTTTGAAGAAGCTGTTTGTGAGATGCAGCTAGACACAAAGGAAGGATTGTCAACGTCGCAAGAGGTAGAAGATCGCCTTGAGTTGACACAGGAAGGAAATCAGGAAATACAGAGGGATGTCGAGGAGCTAGCTGAAATGAAGGAGGATCCAGATGGATTGCGGAATGCGAACGTTTCTCCTGAGACTGATTCGAGAACAAATCCATCAACCTCTTTCCTTTGTTCAGAGTGTGGTTTGACTATAAAGTCGAAATACACGCTGGCCCAGCACATGGCCATTCACAAAAAACAGTTTCAGCGATCACATCTTTGCGAGACCTGCGGCAAGGACTACAGAAGCAGGGCTCAACTGGTAGTTCATAAGAGAACGCACACCGGCGAGCGACCCTATCAATGCACCCACTGCCCGAAGACATATTTTCAGAGCACGGCTCTGAAGACACATTTGATAACCCATGGCAAGGAGCGACCGTACAAGTGCTCACAGTGCCAGAAAGCATTTTATCTGCCGAGGAATTTGAAAGACCACCAAAAGCTGCACAAGGGAGAGAGACCCTTTCAATGTGCCAATTGCCCTTTGGCCTTCACCAAGAAAGCCAACCTGAGGACACACATGCGTCAGCACACAGGAGAGCGACCGTTCAACTGTGATATATGTGGCTTGACTTTTGTCCAGAACCAGCATCTGACAACCCATCTTCGTGTCCACAACGAGGATCGTCCCTTCAAGTGCAACGACTGCGATAAATCATTTTTCGTTAGCGCCAATCTAAAGAAACACCTCCGCGTCCACACTGGCGAGAAGCCCTTCAAGTGCTCTGTCTGTGGACAGGACTTTAAGCACAGCCATCATCTGAAATCCCATGTTCGCAGTCATACGGGGGAGCGGCCCTACAGGTGCAACGAGTGCGAAAAGGCCTTCGCCTCCAATCAGTCGCTGCAGAAACATATTCTGTGGCATGCCAGCAATCGAGATCGGGCCTTCAAGTGTTCCGACTGCCCCAAGGGCTTCGACAGCTTACGCGGCCTTAAATATCATATGCGTTTGCACagctcctcgtcctcctcaaAGGAGATGGCGAAGGTGGAGGCCCTGCACATGTGTCCGATCTGTAGCCTGAGCTTTAGCCTGCAAGACGCCTTGGAAACACACATTGCCATCCACAATAAGGACCTAAATTGA
Protein Sequence: MKTPTNSSILQQCRFCRKTSVASVDIFCKGTTDSSISEMVNGLLSENCQVKRDALPQCACLACILATKSAFSFKRKCEESHRFFSELLLIKSPTHLGGNKLADEDESDEDERLPSEIPFEEAVCEMQLDTKEGLSTSQEVEDRLELTQEGNQEIQRDVEELAEMKEDPDGLRNANVSPETDSRTNPSTSFLCSECGLTIKSKYTLAQHMAIHKKQFQRSHLCETCGKDYRSRAQLVVHKRTHTGERPYQCTHCPKTYFQSTALKTHLITHGKERPYKCSQCQKAFYLPRNLKDHQKLHKGERPFQCANCPLAFTKKANLRTHMRQHTGERPFNCDICGLTFVQNQHLTTHLRVHNEDRPFKCNDCDKSFFVSANLKKHLRVHTGEKPFKCSVCGQDFKHSHHLKSHVRSHTGERPYRCNECEKAFASNQSLQKHILWHASNRDRAFKCSDCPKGFDSLRGLKYHMRLHSSSSSSKEMAKVEALHMCPICSLSFSLQDALETHIAIHNKDLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00603497;
90% Identity: iTF_00601190;
80% Identity: -