Dgua012455.1
Basic Information
- Insect
- Drosophila guanche
- Gene Symbol
- Paris
- Assembly
- GCA_900245975.1
- Location
- NW:400366-404656[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 34 0.00011 0.0067 16.4 2.0 1 23 153 175 153 175 0.98 2 34 0.00011 0.0064 16.4 4.2 1 23 181 203 181 203 0.99 3 34 0.00085 0.05 13.6 1.6 1 23 209 231 209 231 0.93 4 34 4.1e-06 0.00024 20.9 0.9 1 23 237 259 237 259 0.98 5 34 8.4e-05 0.005 16.8 2.4 1 23 265 287 265 287 0.98 6 34 8.1e-06 0.00048 20.0 0.2 1 23 293 315 293 315 0.98 7 34 4.9e-05 0.0029 17.5 4.3 1 23 321 343 321 343 0.99 8 34 1.4e-05 0.00085 19.2 0.9 1 23 349 371 349 371 0.99 9 34 2e-06 0.00012 21.9 3.6 1 23 377 399 377 399 0.99 10 34 4.5 2.6e+02 1.9 0.1 5 20 429 444 428 446 0.89 11 34 3.6e-07 2.1e-05 24.2 5.8 1 23 460 482 460 482 0.99 12 34 1.7 1e+02 3.2 0.1 5 20 492 507 490 509 0.91 13 34 8.1e-05 0.0048 16.8 5.1 1 23 536 559 536 559 0.97 14 34 7.6 4.5e+02 1.2 0.1 5 20 569 584 562 586 0.90 15 34 8.1e-05 0.0048 16.8 5.1 1 23 613 636 613 636 0.97 16 34 0.034 2 8.6 0.2 1 20 642 661 642 663 0.94 17 34 8.1e-05 0.0048 16.8 5.1 1 23 690 713 690 713 0.97 18 34 7.6 4.5e+02 1.2 0.1 5 20 723 738 716 740 0.90 19 34 8.1e-05 0.0048 16.8 5.1 1 23 767 790 767 790 0.97 20 34 0.034 2 8.6 0.2 1 20 796 815 796 817 0.94 21 34 8.1e-05 0.0048 16.8 5.1 1 23 844 867 844 867 0.97 22 34 0.034 2 8.6 0.2 1 20 873 892 873 894 0.94 23 34 8.1e-05 0.0048 16.8 5.1 1 23 921 944 921 944 0.97 24 34 0.034 2 8.6 0.2 1 20 950 969 950 971 0.94 25 34 8.1e-05 0.0048 16.8 5.1 1 23 998 1021 998 1021 0.97 26 34 0.034 2 8.6 0.2 1 20 1027 1046 1027 1048 0.94 27 34 8.1e-05 0.0048 16.8 5.1 1 23 1075 1098 1075 1098 0.97 28 34 0.034 2 8.6 0.2 1 20 1104 1123 1104 1125 0.94 29 34 8.1e-05 0.0048 16.8 5.1 1 23 1152 1175 1152 1175 0.97 30 34 0.01 0.61 10.2 0.1 1 22 1181 1202 1181 1202 0.94 31 34 0.0087 0.51 10.5 7.3 1 23 1228 1250 1228 1250 0.98 32 34 4e-05 0.0024 17.8 0.2 1 23 1256 1278 1256 1278 0.99 33 34 2.4e-06 0.00014 21.7 2.7 1 23 1296 1318 1296 1318 0.98 34 34 1.6 93 3.3 4.3 1 23 1324 1347 1324 1347 0.96
Sequence Information
- Coding Sequence
- ATGGAGGAAATATGCAGAGTTTGCATGGGAACTTCTGGAGcattaacaaacatttttgatgaGACTCCAATAAGACTCCAATCCATTGCTGAAATGATTACGGAGTGCACAGGATACGTGGTTTGGCGAGGGGATGCACTCTCAGAAAAGATATGTCCACCCTGCCTCGAGGATGCAGTGAGTGCATTCTACCTCAAGAGAACCTGCGAGCAGAGCCATAAACTATATTTCACGCGGCTGGAGGaggaaatagaagaagaagaaatctGTGATAATGCAAAAGACGATTGTGACGAGCCGTCGGGTATTGAAAGTGAGCAACTAAACCAGTTGGAAACCGATGCAAAGGATCAAAGTGATAAGGATAAGCTTAGTACGCACCTAATTGATCATCCATACTCCAAGTCATTTCATCTACAAGTACAAACCAGTAAACGACGCGCGTCTAAAAAACCACATAAATGCCCTCGATGCTCAAAGGCATTtactgaaaaagaaaaactagaCGTACACCTCCGTTCTCACGCTGGGGAGCGACCGTACAAGTGTACTCACTGCCCGAAAGCATATATCAGTGAGAAATGTCTTACAAATCACATACAAAGTCACACAGGACATCGACCATATAAATGTTCTTACTGCCAAAGATCATTTCAAGAGAAAGCGTTTCTCGAGAGACACCTACCCACTCACACGAAGGAGCGACCACATAAGTGTCCCGAATGTCCAAAGTCCTATTTTATACCTAATAATCTGAAGATTCACATTCGTACGCACACGGGAGAACGACCATTCAAATGTTCCCTCTGTCCAAAAACCTTTACATCAAAAGGTCCTCTAAGAATTCACAGCCATACTCACACTAAGGAGAGGCCGTTTAAGTGTTCTCAATGCCCCAAGTCCTTCGCTGGAAGCGTAGGTCTCCAAACTCACATGATAATGCATTCCGATGAGCGACCCTTTCAATGCTCCCGCTGCTCAAAGCCATTTAAAAGAAGATGCTCCCTTGCAGCACACACCCGAACTCACACGGGTGTACGAAAATTTCAATGCTCTCAATGCTCAAAGGCCTTTGTAGAAAAACAAGCACTAAGGAAACACCTTCTTACTCACACTGAGGAGCGACCGTACAAGTGTGATCATTGCCCGATATCATTTAGGCAAAAGATATCTCTAACAAGGCacttaaaaaaacatccaGATTATCGAGAACATATATGTTCTCACGGCTCGGAGTCATTCAAAGAGACAGCGGATCTCGACAGACACCTCACCACTCAGACTGACTGCTCAAAGACATTTGAACCTGAAAGATCTGTTAAAAATCACACCTCCAGTCAGTCGCAAAAGACCAAAGATCATATCCTTAAGCAATCTTACAAGTGTGATCACTGCCCTAGATCATTTAAGCGAAAGACATCTCTAACAAAGCACTTAAAAACACATCCAGATTATCGACCACATATAAGTTCTCACTGCTCGAAGTCATTTCAAGAGAAAGCGGATCTCGATGAACACCTCACTGACTGCTCGAAGTCATTTAAAGAGGAAATATCTGTTGAACCGAAAGAGCATCAAATCCTTACTCATACTGGGGAGCGACCGTACAAGTGTGCTCACTGCCCGAGATCATTTAGGCACATGACATCTCTTACAAAGCACATACAATTAAAACATCCAGATTGTCGACCACATATAAGTTCTCACTGCTCGGAGTCATTTCAAGAGAAAGCGGATCTCGATGAACACCTCACTGACTGCTCGAAGTCATTTAAAGAGGAAATATCTGTTGAACCGAAAGAGCATCAAATCCTTACTCATACTGGGGAGCGACCGTACAAGTGTGCTCACTGCCCGAGATCATTTAGGCACATGACATCTCTTACAAAGCACATACAATTAAAACATCCAGATTGTCGACCATATATATGTTCTCACTGCTCGGAGTCATTTCAAGAGAAAGCGGATCTCGATGAACACCTCACTGACTGCTCGAAGTCATTTAAAGAGGAAATATCTGTTGAACCGAAAGAGCATCAAATCCTTACTCATACTGGGGAGCGACCGTACAAGTGTGCTCACTGCCCGAGATCATTTAGGCACATGACATCTCTTACAAAGCACATACAATTAAAACATCCAGATTGTCGACCACATATAAGTTCTCACTGCTCGGAGTCATTTCAAGAGAAAGCGGATCTCGATGAACACCTCACTGACTGCTCGAAGTCATTTAAAGAGGAAATATCTGTTGAACCGAAAGAGCATCAAATCCTTACTCATACTGGGGAGCGACCGTACAAGTGTGCTCACTGCCCGAGATCATTTAGGCACATGACATCTCTTACAAAGCACATACAATTAAAACATCCAGATTGTCGACCATATATATGTTCTCACTGCTCGGAGTCATTTCAAGAGAAAGCGGATCTCGATGAACACCTCACTGACTGCTCGAAGTCATTTAAAGAGGAAATATCTGTTGAACCGAAAGAGCATCAAATCCTTACTCATACTGGGGAGCGACCGTACAAGTGTGCTCACTGCCCGAGATCATTTAGGCACATGACATCTCTTACAAAGCACATACAATTAAAACATCCAGATTGTCGACCATATATATGTTCTCACTGCTCGGAGTCATTTCAAGAGAAAGCGGATCTCGATGAACACCTCACTGACTGCTCGAAGTCATTTAAAGAGGAAATATCTGTTGAACCGAAAGAGCATCAAATCCTTACTCATACTGGGGAGCGACCGTACAAGTGTGCTCACTGCCCGAGATCATTTAGGCACATGACATCTCTTACAAAGCACATACAATTAAAACATCCAGATTGTCGACCATATATATGTTCTCACTGCTCGGAGTCATTTCAAGAGAAAGCGGATCTCGATGAACACCTCACTGACTGCTCGAAGTCATTTAAAGAGGAAATATCTGTTGAACCGAAAGAGCATCAAATCCTTACTCATACTGGGGAGCGACCGTACAAGTGTGCTCACTGCCCGAGATCATTTAGGCACATGACATCTCTTACAAAGCACATACAATTAAAACATCCAGATTGTCGACCATATATATGTTCTCACTGCTCGGAGTCATTTCAAGAGAAAGCGGATCTCGATGAACACCTCACTGACTGCTCGAAGTCATTTAAAGAGGAAATATCTGTTGAACCGAAAGAGCATCAAATCCTTACTCATACTGGGGAGCGACCGTACAAGTGTGCTCACTGCCCGAGATCATTTAGGCACATGACATCTCTTACAAAGCACATACAATTAAAACATCCAGATTGTCGACCATATATATGTTCTCACTGCTCGGAGTCATTTCAAGAGAAAGCGGATCTCGATGAACACCTCACTGACTGCTCGAAGTCATTTAAAGAGGAAATATCTGTTGAACCGAAAGAGCATCAAATCCTTACTCATACTGGGGAGCGACCGTACAAGTGTGCTCACTGCCCGAGATCATTTAGGCACATGACATCTCTTACAAAGCACATACAATTAAAACATCCAGATTGTCGACCATATATATGTTCTCACTGCTCGGAGTCATTTCAAGAGAAAGCGGATCTCGATGTACACCTCCTCACTCAGACTGAGTGCTCGAAGTCATTTGAACATGAAATATCTATCAAGTCGCAAAAGAAACACACTACAGAGCTACCGTATAAGTGTGAGCTCTGCTGCAAGTCCTTTCCTAAAAAGTCCCACCTTCGGGAACACACTTTTACGCACATAGATGATGAACCATTTCAATGTCCTCAGTGCGCGAAATCATTTAAAGAGCAAGAGGTCCTCGAGATGCACATTCAAACACATGCGAAGGAGCGACCATATACGATTTCCGACGGCTATCCCAACGTCAGTGTGTTTATGTGTCCTCACTGCTCGAAGACATTTCCTCAATACGCAAATCTCCGCTATCACCTCCGTTCGCACGCGAACGCACGACCCTACCACTGCTTCTTATGCAGAGCGACGTATACGCAATTATGCAGGCTCAAAGAACACTTATTAAGTGCTCACAATATCGAAAACAATCGATCATTTAGCCGGCCATCTGGTTATACAACTAAATTTATAGAACAAAATCATTTATAA
- Protein Sequence
- MEEICRVCMGTSGALTNIFDETPIRLQSIAEMITECTGYVVWRGDALSEKICPPCLEDAVSAFYLKRTCEQSHKLYFTRLEEEIEEEEICDNAKDDCDEPSGIESEQLNQLETDAKDQSDKDKLSTHLIDHPYSKSFHLQVQTSKRRASKKPHKCPRCSKAFTEKEKLDVHLRSHAGERPYKCTHCPKAYISEKCLTNHIQSHTGHRPYKCSYCQRSFQEKAFLERHLPTHTKERPHKCPECPKSYFIPNNLKIHIRTHTGERPFKCSLCPKTFTSKGPLRIHSHTHTKERPFKCSQCPKSFAGSVGLQTHMIMHSDERPFQCSRCSKPFKRRCSLAAHTRTHTGVRKFQCSQCSKAFVEKQALRKHLLTHTEERPYKCDHCPISFRQKISLTRHLKKHPDYREHICSHGSESFKETADLDRHLTTQTDCSKTFEPERSVKNHTSSQSQKTKDHILKQSYKCDHCPRSFKRKTSLTKHLKTHPDYRPHISSHCSKSFQEKADLDEHLTDCSKSFKEEISVEPKEHQILTHTGERPYKCAHCPRSFRHMTSLTKHIQLKHPDCRPHISSHCSESFQEKADLDEHLTDCSKSFKEEISVEPKEHQILTHTGERPYKCAHCPRSFRHMTSLTKHIQLKHPDCRPYICSHCSESFQEKADLDEHLTDCSKSFKEEISVEPKEHQILTHTGERPYKCAHCPRSFRHMTSLTKHIQLKHPDCRPHISSHCSESFQEKADLDEHLTDCSKSFKEEISVEPKEHQILTHTGERPYKCAHCPRSFRHMTSLTKHIQLKHPDCRPYICSHCSESFQEKADLDEHLTDCSKSFKEEISVEPKEHQILTHTGERPYKCAHCPRSFRHMTSLTKHIQLKHPDCRPYICSHCSESFQEKADLDEHLTDCSKSFKEEISVEPKEHQILTHTGERPYKCAHCPRSFRHMTSLTKHIQLKHPDCRPYICSHCSESFQEKADLDEHLTDCSKSFKEEISVEPKEHQILTHTGERPYKCAHCPRSFRHMTSLTKHIQLKHPDCRPYICSHCSESFQEKADLDEHLTDCSKSFKEEISVEPKEHQILTHTGERPYKCAHCPRSFRHMTSLTKHIQLKHPDCRPYICSHCSESFQEKADLDEHLTDCSKSFKEEISVEPKEHQILTHTGERPYKCAHCPRSFRHMTSLTKHIQLKHPDCRPYICSHCSESFQEKADLDVHLLTQTECSKSFEHEISIKSQKKHTTELPYKCELCCKSFPKKSHLREHTFTHIDDEPFQCPQCAKSFKEQEVLEMHIQTHAKERPYTISDGYPNVSVFMCPHCSKTFPQYANLRYHLRSHANARPYHCFLCRATYTQLCRLKEHLLSAHNIENNRSFSRPSGYTTKFIEQNHL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -