Dgri009431.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila grimshawi
Gene Symbol
RREB1
Assembly
GCA_018153295.1
Location
JAECXY010000847.1:5596680-5602896[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.014 0.93 9.8 0.8 1 21 3 23 3 25 0.93
2 11 0.0014 0.092 13.0 0.1 1 20 35 54 35 56 0.95
3 11 0.094 6.1 7.2 1.7 2 20 167 185 167 187 0.93
4 11 0.0063 0.41 11.0 0.2 1 23 335 357 335 357 0.97
5 11 4.9e-06 0.00032 20.7 0.7 1 23 367 389 367 389 0.99
6 11 0.00033 0.021 15.0 2.0 1 23 395 418 395 418 0.97
7 11 3.4e-05 0.0022 18.1 0.3 2 23 607 628 606 628 0.97
8 11 0.058 3.7 7.9 6.3 1 23 634 657 634 657 0.97
9 11 3.8 2.4e+02 2.2 3.4 1 23 775 798 775 798 0.78
10 11 0.0034 0.22 11.8 0.5 3 23 862 882 860 882 0.96
11 11 0.00053 0.035 14.3 4.8 1 23 888 910 888 910 0.99

Sequence Information

Coding Sequence
ATGAAATATCTGTGCCCCATTTGCGAGGTCGTCTCGGCCACACCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTACTGTCGTCGGCATCCTCGCTGGACCGGCATGTCCTGCTGGAGGATGAGCAGCTAGTGCTGAGCAGCAAACAGCGACGCCACAAGGCAGCCCTAAACAACAACAATATAATTAGGGATGAGGAGCACGAGAATCGGCCGGATGATGATTCGGATGTGGATAGCGCTGATAGCGTTGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGCTACTCGCCTCGGGCGGCACCTCGCCCACCCACTCGAATTCGGAATCGCATTCACCGCCGCTGCTGCTGCAGAGCTGCCCGGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGCGGACATACCGGCCAAGTGTCGCGAGTGTGAGGTGATCTTTGCCACACATCGACAGCTACAGGCGCACAGCTGTCGAGGACTGCCGCCGCTGCTTGGTGTGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAACTGGAGGAGCAGCACCAGCAACAGCAGCAGCACGAGGAGGACCACGAGCAGCAGCAGCACAAGCAGGAGGAACAGGAGCAGGCTGAACAGCGCGAATGCGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTGCTTCCCTCACCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAACATGACCAGTTCCAGCTGCACCTCGAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATATAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTTCGTCGCATGAAACTGCGCGGTGAATTCCCCTGCAAGCTGTGCACCGCCGTCTTTCCCAATCTGCGGGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCCGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTGCGGCACATGCGCACCCACAACGGTGATCGGCCCTACGAGTGCGCCGTCTGCAATTATGCGTTCACCACCAAGGCGAACTGTGAGCGACATTTGCGCAATCGACATGGCAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCGCGGACCGAGGCCGATATCCTGACGGAGTTGAGCGGCTATCGTTCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCGCCGAAAAGCAGCCGCATCCTCAATCGGAGTCAATTGGCGGCAATAAGCCGGCGACGCCAACCACAATGAAAACGATGATTGCACAAGCTGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTCGCCAAACTGGTGGACAATGCGACCAGCAATCAGGTGTCGTTCAACAGCTATTTCCGTCCCAGCGACGTCGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTTGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGATGTGACCAGCAGCAGCAGCAGCTGCGGCAATGACACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAACCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTTACCACGAAGAGCAACTGCGATCGCCATCTGTTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATACCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAAGCCGAACAGGCCGAGCGTGAGCAGCGCGAGCGCCAAAAGGAGCGCGAACGTGAACTGGAATTGGAACGGGAACGTGAGCGGGAACACCAACAGTTGATACAACAGTTGCGCCAACAAATGGCTGCTGCTGCAGCGGCTGCTGTCGCTGTGGCCGCCGTTGCTGCACCAGCGCATCCACCACCGCCAGACCAATCGCCACCAGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGTGAGTTCTCATTCGGCGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCACGCCCACGAGTTCGCCCTGCTGCTGGCCAAGGGAGCCATCGAAACGGATGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCGCATTCGGATGATGAGGCGGCTGCTGTCGGCACCAGATCGGGCAAATATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGGCGCCACATGCGCACCCACTCCGGTGAGCGGCCATTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAGCTCGATCATCAATCCGATTGCTCCGAAGATGAGCAACTTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCAGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTAA
Protein Sequence
MKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLLEDEQLVLSSKQRRHKAALNNNNIIRDEEHENRPDDDSDVDSADSVAQVITSTPDVATLLASGGTSPTHSNSESHSPPLLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECEVIFATHRQLQAHSCRGLPPLLGVSSSPLHKQEESELEEQHQQQQQHEEDHEQQQHKQEEQEQAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTEADILTELSGYRSETILEQAIKEREEKAAEKQPHPQSESIGGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREHQQLIQQLRQQMAAAAAAAVAVAAVAAPAHPPPPDQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHEFALLLAKGAIETDAXXXXXXXXXXXXXXXXXXXXPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSEDEQLDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00599078;
90% Identity
iTF_00599078;
80% Identity
-