Basic Information

Insect: Drosophila grimshawi
Gene Symbol: Znf574
Assembly: GCA_018153295.1
Location: JAECXY010001366.1:14176343-14178610[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.028 1.8 8.9 0.4 2 23 296 318 295 318 0.96

2 10 2.6 1.7e+02 2.7 0.2 6 23 328 345 328 345 0.97

3 10 0.00082 0.053 13.7 0.1 1 23 351 373 351 373 0.94

4 10 8.7e-06 0.00057 19.9 0.3 1 23 386 409 386 409 0.97

5 10 9.9e-05 0.0064 16.6 1.2 1 23 417 440 417 440 0.97

6 10 1.6e-05 0.001 19.1 1.1 3 23 448 469 446 469 0.92

7 10 0.00084 0.054 13.7 0.5 2 23 481 503 480 503 0.97

8 10 3.1e-05 0.002 18.2 3.6 1 23 510 533 510 533 0.93

9 10 2e-06 0.00013 22.0 1.2 1 23 539 561 539 561 0.98

10 10 4.8e-05 0.0031 17.6 1.4 1 23 567 590 567 590 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.028	1.8	8.9	0.4	2	23	296	318	295	318	0.96
2	10	2.6	1.7e+02	2.7	0.2	6	23	328	345	328	345	0.97
3	10	0.00082	0.053	13.7	0.1	1	23	351	373	351	373	0.94
4	10	8.7e-06	0.00057	19.9	0.3	1	23	386	409	386	409	0.97
5	10	9.9e-05	0.0064	16.6	1.2	1	23	417	440	417	440	0.97
6	10	1.6e-05	0.001	19.1	1.1	3	23	448	469	446	469	0.92
7	10	0.00084	0.054	13.7	0.5	2	23	481	503	480	503	0.97
8	10	3.1e-05	0.002	18.2	3.6	1	23	510	533	510	533	0.93
9	10	2e-06	0.00013	22.0	1.2	1	23	539	561	539	561	0.98
10	10	4.8e-05	0.0031	17.6	1.4	1	23	567	590	567	590	0.97

Sequence Information

Coding Sequence: ATGGCAGCCTGTGTGCTATGCTTCGACTGCTGCAAGACCGGCGAGTCGTACAAGATATTTTCCGAGGCCGGATTGCGGCTCAAAATTTGCAAAACAATAAACAAACATTTTTGGCTGGAGCTGAGCAACGCAGCGGGAGGCGAACGCGAGGAAATTTGCCACCAATGCTGGCAGGTCGTGAGCAACTTTAATAAATTATACGAGCGAGTTTACAACTTGCACCAGGAGCGCCTCTGTGATGTGAAGAACGTCACGATTGAATTCTGTGACGAGGCGGAGGCAGCGAATCCTCTAGCCCTTGGCGGTGAACTGGATGCACTCGCCGAGGATTTCTTTGCGTCCGGCGATGTCAAGGTGGAGGTGAACGAACTGGAGCCGCTGCCCAAGCTCGAAATGCTCGATGAGCCAGTGGTCGAGGAGCAGAGCAGGGCATCCAAACGTACCAGTGCCGAGCGTTCAGCTGCTAAGAGGCGCATCAAAAACGAACAGCTAACCATCTCCAGTGACTCGGATGGGGACATTCCCTTAGCTGAGTTCCTTGATCTTAAAACGACTGCAAAGCCAGGAGGAGTAGTAGCAGCAGCATCGCCGCTCATTGGACGACAGCTGCGAAGAAGCACTCGACGTGAAGCAGTGCTAGGCACTGAGGACAGTGCCAGTTCCAGCGAGAGCAGCGACGGCGACTCTGGCGACAGTCTGCCTGATGTCGAGCCGGAGGAGCGCTACGCAGAGATACCCAAACGGGTTGTAGTCAAGCCCAAAAAGTATCGAAAGCGTCCCAAACCGCTGGTCGCGCCGGTGCGCATGAGTCGCGACGATCTCGCCAAACGACGGGCGCAACAAAAGAAATACGATGAAATTATATTTGAGTTTTTCAAGAAGCTGCCATGTCACGTATGCAATCTGTTGGTGCCCAATTTCGGAGACATGCGTCGTCATCTGCGCATGTCCCACAACATCGAAAGTGGCTTCATTGCCTGCTGTGGTCGCAAGTTTCACATACGCAGGGGTCTGGCCGAGCATGTGCTGGTGCACAATAACCCGGAGCACTTTATGTGCGCCCCGTGCGGTCGCGTCTTTCAGGACTCCAAGACGTTGGAGGCGCACGAGCAAACGCACACGAATCCCATGGCAGATGCGAAGGATAAACGCATTTACCCATGCGACAAGTGTCCGAAAACCTTCACCACAAAGGCCGCCGTCGAGTATCACATTATGTCCAAGCATGTGCCCAAGTCGGACTTCAAGTACACCTGCCCCGAGTGCAATAAGAAGCTGCCCACAGAGCGAAAGCTGAAGGAGCATCGACGGTATATGCACGATCCGGAGACGGCAATCATTTGCGACAAGTGCGGCAAAACGTTGCGTACCCAGGCCAATCTTAAGAAACATCACGAACTGGAGCATTCCGATGAGCCACGCCCGAAGCCGGATCCCGTGCAGTGCGAGATATGCGGCACCTGGTTGCGCCATTTATCCGGCCTCAAGCAGCACATGAAAACGGTGCACGAACCACCGTGTGGCGAGCATCGCTGCCCCATCTGCGACAAGACATCAACTAACTCCCGAGCACTCAAGCGGCACATTTACCACAATCATCAGTGCGAGAGAAAGTTTCGCTGCACCATGTGCGAGAAGGCCTTCAAGAGGCCACAGGATTTGAGAGAGCACACATCGACACACACAGGCGAGGTGTTGTACACCTGTCCCAACTGTCCGCAGACGTTCTTCTCGAATGCCAACATGTACAAGCATCGCCAGAGATTGCATCGCGCCGAATGGGAAGCGGATCGCAAGAAACCACTGCCACCCAACATAATGCAGCAGGCGGCCATGAAGAAGCGACAGGGCAGCAAGGCTGCCGCACCAACGCTGTTCCCCCCATCCGCAGAGACGCCAACTGCACCAGCTGCCCAAAAGCCGGAATCGCAACAACAACCACAACAACAACTGCATTAG
Protein Sequence: MAACVLCFDCCKTGESYKIFSEAGLRLKICKTINKHFWLELSNAAGGEREEICHQCWQVVSNFNKLYERVYNLHQERLCDVKNVTIEFCDEAEAANPLALGGELDALAEDFFASGDVKVEVNELEPLPKLEMLDEPVVEEQSRASKRTSAERSAAKRRIKNEQLTISSDSDGDIPLAEFLDLKTTAKPGGVVAAASPLIGRQLRRSTRREAVLGTEDSASSSESSDGDSGDSLPDVEPEERYAEIPKRVVVKPKKYRKRPKPLVAPVRMSRDDLAKRRAQQKKYDEIIFEFFKKLPCHVCNLLVPNFGDMRRHLRMSHNIESGFIACCGRKFHIRRGLAEHVLVHNNPEHFMCAPCGRVFQDSKTLEAHEQTHTNPMADAKDKRIYPCDKCPKTFTTKAAVEYHIMSKHVPKSDFKYTCPECNKKLPTERKLKEHRRYMHDPETAIICDKCGKTLRTQANLKKHHELEHSDEPRPKPDPVQCEICGTWLRHLSGLKQHMKTVHEPPCGEHRCPICDKTSTNSRALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMQQAAMKKRQGSKAAAPTLFPPSAETPTAPAAQKPESQQQPQQQLH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508523;
90% Identity: iTF_00616353;
80% Identity: -