Basic Information

Insect: Drosophila grimshawi
Gene Symbol: -
Assembly: GCA_018153295.1
Location: JAECXY010001368.1:3846315-3854481[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00019 0.012 15.8 3.4 1 23 259 281 259 281 0.98

2 11 0.00091 0.059 13.6 10.5 1 23 287 309 287 309 0.96

3 11 9.1e-05 0.0059 16.7 6.5 1 23 315 337 315 337 0.98

4 11 0.00028 0.018 15.2 2.3 1 23 343 365 343 365 0.95

5 11 2e-05 0.0013 18.8 0.5 1 23 371 393 371 393 0.97

6 11 1.7e-06 0.00011 22.1 0.1 1 23 399 421 399 421 0.98

7 11 0.00011 0.0073 16.5 2.0 1 23 426 449 426 449 0.97

8 11 0.047 3 8.2 0.3 1 23 455 478 455 478 0.94

9 11 0.00015 0.0097 16.1 0.1 1 23 536 558 536 558 0.98

10 11 0.014 0.88 9.9 2.7 1 23 672 694 672 694 0.95

11 11 0.004 0.26 11.6 4.9 5 23 707 725 699 725 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00019	0.012	15.8	3.4	1	23	259	281	259	281	0.98
2	11	0.00091	0.059	13.6	10.5	1	23	287	309	287	309	0.96
3	11	9.1e-05	0.0059	16.7	6.5	1	23	315	337	315	337	0.98
4	11	0.00028	0.018	15.2	2.3	1	23	343	365	343	365	0.95
5	11	2e-05	0.0013	18.8	0.5	1	23	371	393	371	393	0.97
6	11	1.7e-06	0.00011	22.1	0.1	1	23	399	421	399	421	0.98
7	11	0.00011	0.0073	16.5	2.0	1	23	426	449	426	449	0.97
8	11	0.047	3	8.2	0.3	1	23	455	478	455	478	0.94
9	11	0.00015	0.0097	16.1	0.1	1	23	536	558	536	558	0.98
10	11	0.014	0.88	9.9	2.7	1	23	672	694	672	694	0.95
11	11	0.004	0.26	11.6	4.9	5	23	707	725	699	725	0.92

Sequence Information

Coding Sequence: ATGCCCTATCTGTTATCCACGGATGGATCATTGGCCGTACAAAAGGATGTTAAGGGCGCACTCTCCAGCAATAAGGGCAATGTCGTTCGTCGCATGTTCGTCGTGAACGATTCCTCATTTGCGCCCGGAACACAAAGAGTAATTACCACAGGCTCCGCATCGACGGTGGTCAAAAAACAGGACTCTGGTCAGCAAGTGTTGAGCATAAATTCGCTCGATAAGAATTATCTTTTGGTCGATCAGGCAACAGCGGCAGCAGCTGCAGCTGCAGCAGCAGCGGGCGGAGGAGGTGATCCGGCAGCGGCGGCGGCCCACCACCATCATCATCATCATACATTGACAAATGGTGGCAGCATTGTTGATGCCAAAACTGGACAAACCGTATTGACATCGGCGGCGGCGGCGGCAGCGGCGAGCGCTGCGGCAGCCAAATCGCATTTTAGCTCTATTGGTGCACTGCATCTCACCCAAGAGGAGTGCAATGAGATACTAATTAAGCGCGCCATTGCAGCCGGCCACGGCCATCATCATCAGACGCACCCAACAGCAATCACCAACGCTGGCGACGGAGCGCACCATCATCATTCGGCGCCAGGCGCGACACCAATTCAAGTACAGAAAGTAATACAAGGACTCGAAGAGAACGAGGACTCGCAGGGCGACGCACCCAACTTAAAGTTGGAGCCAGGCACATTAGAATTGTCCCCAAAGACCGAACTACAGGAATCAATGCATTTCAGCGAAACCGACGCCACCATCAAAAAGGAGCGCCCGTACAGTTGTGACGAGTGCGGCAAATCCTTTCTGCTCAAACATCATTTGACAACACACGCACGCGTGCACACAGGTGAACGACCCCATATTTGCACACATTGCGGCAAGAGTTTTGCGCACAAACACTGTCTGAATACGCATCTGCTGTTGCATTCAACGGATCGGCCATATCAGTGTCAGGAGTGCAAGAAGAGTTTCACACTCAAGCATCATCTGTTGACGCATTCCCGGGTCCACAGCCGGGAGCGACCGTTCGTTTGCCAGGAGTGCGGACGATCCTTTCCTCTCAAACGGCATCTGGTCACGCACAGTAAATTTCACGCCGGCGAACGTCCCTACGTCTGCGAGGAATGCGGTGAGAGTTTCGCACAGGAGAACCATCTGATTATGCACTCGCGCTTTCATGGTTCATTGAATCCATTTGTTTGTCCTGATTGCGGTGCCTCGTTTCCACGCAAATTTCAATTGGTTAATCACGGACGCATACACGGCAAGATACCACACTCCTGCACCGTTTGCGGCAAAGAGTTTCTACAGAAGCGCACACTAGTTTCCCACATGAGGCGCGTACATACCGGCGAGCAGGCGCATCCTTGCGTCAGCTGCGGCGAAGGTTTCCTCACCAAGGCGGAACTGCATCAGCATGTGCGTGCGGCGCACAATGGCGTCAATCCCAATACGAGCAGCGCCACCATTATAGCCAATCAACAGATACAACAGCCGCATCATCATCCGGGACATCCGCAGACCATAACCGTTGTCAGCAATCCGGCTAACTCAACGCTGCTCACCGTCTCCACAACCGATGCGAATGGCGTGGCGCGTCCACAATTCGTTTGCCGTGAATGCGGCAGCGCGTTTAATAGTCGGGAGGCGCTCGCCTTGCACTTGCGACTGCACACCGGCGACAAGAGTCTGATGACCGATTTGTGTGCGCTAACAGCGGCCCTGCCGGGACACTTTTTGAGTACGGCCAGCTTAAATCCGGGCACTGTGGTTACGGCCAATCCGAATATGGTTGGGCAGAGTCCGGTGCCGGTGCAAATCATATCATCGACCGGTCAGGTGATGTCGCAGACCACACTGGTGCAGGCCGCCAATTCGACGCATCCGCAAGCTGTGGTCACCGCCGTGCCCACAATGCCCCTCCACGGGCAACATCATCTGCAGCACATCCAGCAGCAGCAGCAGCAGCAACAACATGTCGTCACCGTTTCACCGGCCAACAAACCCAAATCGCATTTCTGCGCCAGCTGCGGCAAGGGATTCGCCGCGAAGCACGGCCTCATGCAACACAATCGCAGGCATCCGAACGGCGGCTGCACGGTGCGCACCCATGTCTGCGAGTGTGGAAAGGCGTTCTTCCAAAAGAATCATCTGATGCTGCATCAGCGCCAGCATTTGGAAACGAAGCCAGCCATATCGCAGCAACAGCTTGTTGTACCAACTACTTCTTACTAA
Protein Sequence: MPYLLSTDGSLAVQKDVKGALSSNKGNVVRRMFVVNDSSFAPGTQRVITTGSASTVVKKQDSGQQVLSINSLDKNYLLVDQATAAAAAAAAAAGGGGDPAAAAAHHHHHHHTLTNGGSIVDAKTGQTVLTSAAAAAAASAAAAKSHFSSIGALHLTQEECNEILIKRAIAAGHGHHHQTHPTAITNAGDGAHHHHSAPGATPIQVQKVIQGLEENEDSQGDAPNLKLEPGTLELSPKTELQESMHFSETDATIKKERPYSCDECGKSFLLKHHLTTHARVHTGERPHICTHCGKSFAHKHCLNTHLLLHSTDRPYQCQECKKSFTLKHHLLTHSRVHSRERPFVCQECGRSFPLKRHLVTHSKFHAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCPDCGASFPRKFQLVNHGRIHGKIPHSCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRAAHNGVNPNTSSATIIANQQIQQPHHHPGHPQTITVVSNPANSTLLTVSTTDANGVARPQFVCRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHFLSTASLNPGTVVTANPNMVGQSPVPVQIISSTGQVMSQTTLVQAANSTHPQAVVTAVPTMPLHGQHHLQHIQQQQQQQQHVVTVSPANKPKSHFCASCGKGFAAKHGLMQHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLETKPAISQQQLVVPTTSY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01556276;
90% Identity: iTF_00803779;
80% Identity: -