Basic Information

Insect: Drosophila grimshawi
Gene Symbol: zfh1
Assembly: GCA_018153295.1
Location: JAECXY010000311.1:30080805-30086599[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.9e-05 0.0012 18.9 1.0 1 23 152 174 152 174 0.97

2 14 0.00059 0.038 14.2 1.2 3 23 182 202 180 202 0.94

3 14 6.4e-05 0.0042 17.2 0.1 1 23 288 310 288 310 0.98

4 14 0.00022 0.014 15.5 0.9 1 23 316 338 316 338 0.98

5 14 0.51 33 4.9 4.3 1 23 371 393 371 393 0.87

6 14 0.0028 0.18 12.0 0.4 1 23 399 422 399 422 0.98

7 14 0.019 1.2 9.4 0.4 3 19 431 447 430 448 0.95

8 14 0.00011 0.0073 16.5 5.6 1 23 457 479 457 479 0.97

9 14 0.029 1.9 8.9 1.2 2 23 485 506 484 506 0.96

10 14 6.5e-06 0.00042 20.3 1.0 1 23 515 537 515 537 0.98

11 14 0.00074 0.048 13.9 0.1 3 23 545 565 543 565 0.97

12 14 4e-05 0.0026 17.9 0.5 1 23 571 593 571 594 0.95

13 14 0.034 2.2 8.7 0.4 1 23 604 626 604 626 0.97

14 14 0.00036 0.023 14.9 0.8 1 23 1029 1051 1029 1051 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.9e-05	0.0012	18.9	1.0	1	23	152	174	152	174	0.97
2	14	0.00059	0.038	14.2	1.2	3	23	182	202	180	202	0.94
3	14	6.4e-05	0.0042	17.2	0.1	1	23	288	310	288	310	0.98
4	14	0.00022	0.014	15.5	0.9	1	23	316	338	316	338	0.98
5	14	0.51	33	4.9	4.3	1	23	371	393	371	393	0.87
6	14	0.0028	0.18	12.0	0.4	1	23	399	422	399	422	0.98
7	14	0.019	1.2	9.4	0.4	3	19	431	447	430	448	0.95
8	14	0.00011	0.0073	16.5	5.6	1	23	457	479	457	479	0.97
9	14	0.029	1.9	8.9	1.2	2	23	485	506	484	506	0.96
10	14	6.5e-06	0.00042	20.3	1.0	1	23	515	537	515	537	0.98
11	14	0.00074	0.048	13.9	0.1	3	23	545	565	543	565	0.97
12	14	4e-05	0.0026	17.9	0.5	1	23	571	593	571	594	0.95
13	14	0.034	2.2	8.7	0.4	1	23	604	626	604	626	0.97
14	14	0.00036	0.023	14.9	0.8	1	23	1029	1051	1029	1051	0.98

Sequence Information

Coding Sequence: ATGAACAATCCGAACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAGCGCCGTCGTCGACGACAGCGAATCAGAGATGACAGCAGCATATTTGGTCAACGCTGACGCCAATGGAAGCATTTCCAACGATGACGATCTCGATCATATGGCAGCCGAGAATCTCATCTTTATGGCACGCGACGGCCAACTGAGCGAAATCATCGCCGCCAATGAGGCAAATGGCGGCAGCAGCACAGTGCTAATCACGGAGAGCGATGGAAATACCGGTGTCGAGTACGCCGAGTCCTTTGAAGATGATGCCCAAGTCGTCACCGAGGAGATCATCACGGATGATTGGGTACAGCATCAGGGTGCAGAGAGAGTGGAAATTGCCGCTGAGCAAATCGCTGGCAACGGCAGCTCGCAGGAGCTATTGGACATGCAACAGAATGAGTATATGGCGATGCGTCCCTATCCCTGTGACTTTTGCAGTCGACGGTTTCGGAAGAAGGCCAGCCTCAACAATCATATGCTGGCGCATCAGAATGATCGTCCCCATCTCTGCAAGCTCTGCGGGGCGCGTTTCTCGCGTCGCGCGGAGCTCATCAGTCACTTCAAGGCGCATGCGGAGGCCCAGCTCAAGGAGGAGAGTTCGCAATATATTGTGATTGGCTCCGATAAACCGGAGGCGGAGACGGAGACGGAGTTGCCTCAATACATGCATTGCGAGGCGAATTGCGATCAATCACTTGCCACCAACAACAACCAACTCCAATCAACATCCAACAATGATGTTGCAACTGCTGCTAATGATGGAGCACAGGGGCAGGGGCAGGGGCAGGCAACGCTGCGCTTTCCCGTGCTCGACGAGAGCAAACCCTTCGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCGCTCGTCTCCCACATCAAGAATCATCGCGTGGATTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAACTACAGTCTGCAGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAACTCGGAATATGATCCGGCATCGGCGGGCGAGGAGGATACGGCGAGCGAATCGGAGGCGGACCAGCTTTACGATGCGCCACATTGTTGCCACACCTGCGGCAAATCATTTCTCAGCGTACTCAAACTGCTCGCCCATACCGAAATCCACAAACGCTTCCCGCCATTCAAATGTGTCCTGTGCGGTGTCAGTTTCTACGAGGAGCAGGCCATAAAGCGGCACCTGAATACGCGGCATCCGCATGAGCTGAAGCCCAATTCGTGTGTGTTGTGTGGCAAGGAGTGTCGAGATCGGAAGGCGCTGATCAAACATGCTTGGGATCATTCACGGGAGAAGTGCCACTCGTGTTCCAAGTGTGGCAAGAATTTCCACAACAAGGCGCGCCTGAAACGACACATGGCATCGCATCGCGACAAGTCCGTCGTGTGCGAAGTGTGCCACGAGGAGTTCCCAGATGGACGCACCTTGTCCAATCATCGGCATTCCCACAGCACAACGTCGCCGGGCAAACTGTTCCCCTGCCACGAGTGTGGCAAGACTTTTGGGTCGCGCAGCTCGCAACAGATTCATGTGCGCATCCATACGGGTGAAAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCTGATGGTGGCACTCTCCGCAAACACGAACGCATCCACACGGGCGAGAAGCCCTATGCCTGCTCCGTCTGTCCGCGTGCCTTTAATCAGCGTGTCGTGTTGCGGGAACACATCCGGTCGCATCATTCCGGTCTGGATGCGGCACGTGGCACGTATCACTGCACGGTCTGCTCCGCAGATTTGAGCTCATCGAATGACCTCATCCAGCATCTCATCCAGCACAGTGATACAAACACAGCCAAACAGCGACAGCCAATTACCGGTCCACGTAAATATAAACGTCGCCGGAAACTGCAGCCGCATGAGATTGCACACATGCGCGCAGAGCACAAGGCTGGCGGTGGTGAAGGCGAGGAGGAGGATTATGGCAGCGACTTGGACTACTGCGATCTGGATGTAGAGAATGTGGATGAACTGTTGCAGGAGACAGCCGCAGAGCCACCACCACCAGCCACCAAAAAAGCGAAACGCAAACGCAAAGCGCCAAATAAAACCGGCGATGAGCAAAGATTGTGGGATGAGAAATTCATGCAGCAGGCGAGCAATGGGAACAGCGATGAGGCCTACAAGAGTTTCTTTCAAATGGACTCGCTGGTCGTGGTCAATGATCAAACGTTGCAGCCCGTTGATGCTGGTGTTGCCACGACCAAGTTGCAGCAGGCGGAGATTAAGGAGCAAAAACTCAAAACAGGCAGTCGCACCAGCAAAAGAAGGGCAGGCAAATCTGGGGGAGGAGCAGCAGGAGGAACAGCAGGAGTAGTAGAAACTGTTGCTGCTCCACGTCCCCGCATGATACACACAGCCAAGTCGCAGCAGACACCGCCAAGAAAATCCCGCACAAGGAATCTCGAGGAGATATTGCGTAGTCCCCCCAAACATGAGCGAAACGATCGACGGCTGCGCTTCACCAGCGAATCGTCGACGACGCCACAATTTCTGCCCGGCGAGGAGGAGGAACATCATCTCATCAAGATCGAGCCAACGTCACCGGATCTACGCGAAATGGTCGAGAGCCAGCAGCCAGCCACACTGCCCACATCCTCCTCTGCCGCCTGCTCAACGGCGGCACGCACTTCCCGCCATCTGCGACAGCTGACTGCCAATGGTTCCAGTTCCATTTCCACTGCCACTTCCAGTTTCAGTTCCAGTGGCGCCGCCAGCACGCGAGCGGCTGCCAAGCGCAATGCCAGCAAGCAGCGTGCCAAGAAATCCACATCCAATAGCAGCAAAGCCAACTCATCATCGTCTTATCTCAGCTATGGCGTCGACTCCTATAATGTGGGCGTGGCAGCCAGTTCCAATGGCTCCTCGGATGTCACTTCCGGTTTCTTTTCCATTTCCGAGGTCGTCTCGGCAGCGGATGCAGCCGATGCAGCTGCGAAGGCGGCGGCGGCAGCAGCTAGCAAAACGGAGCGAAGAACGCGCTGCTTTGAGTGCGAAATGTGCTCGTCCAATTTTCCAGATCGCTCACAGCTGCTGGAACACATGCACATACACATCTAG
Protein Sequence: MNNPNYGGIQWIQQESSAVVDDSESEMTAAYLVNADANGSISNDDDLDHMAAENLIFMARDGQLSEIIAANEANGGSSTVLITESDGNTGVEYAESFEDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQLKEESSQYIVIGSDKPEAETETELPQYMHCEANCDQSLATNNNQLQSTSNNDVATAANDGAQGQGQGQATLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEEDTASESEADQLYDAPHCCHTCGKSFLSVLKLLAHTEIHKRFPPFKCVLCGVSFYEEQAIKRHLNTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGGEGEEEDYGSDLDYCDLDVENVDELLQETAAEPPPPATKKAKRKRKAPNKTGDEQRLWDEKFMQQASNGNSDEAYKSFFQMDSLVVVNDQTLQPVDAGVATTKLQQAEIKEQKLKTGSRTSKRRAGKSGGGAAGGTAGVVETVAAPRPRMIHTAKSQQTPPRKSRTRNLEEILRSPPKHERNDRRLRFTSESSTTPQFLPGEEEEHHLIKIEPTSPDLREMVESQQPATLPTSSSAACSTAARTSRHLRQLTANGSSSISTATSSFSSSGAASTRAAAKRNASKQRAKKSTSNSSKANSSSSYLSYGVDSYNVGVAASSNGSSDVTSGFFSISEVVSAADAADAAAKAAAAAASKTERRTRCFECEMCSSNFPDRSQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -