Dgau009720.1
Basic Information
- Insect
- Drosophila gaucha
- Gene Symbol
- Hivep2
- Assembly
- GCA_035045545.1
- Location
- JAWNOY010000284.1:701245-710522[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.00073 0.052 14.1 0.6 1 23 256 278 256 278 0.98 2 8 0.0015 0.11 13.1 3.6 1 21 284 304 284 308 0.89 3 8 0.012 0.87 10.3 0.1 1 19 906 924 906 927 0.93 4 8 2.7e-06 0.00019 21.8 2.0 1 23 1601 1623 1601 1623 0.99 5 8 3e-05 0.0021 18.5 5.3 1 23 1629 1653 1629 1653 0.92 6 8 0.00056 0.04 14.5 3.4 2 23 2072 2093 2072 2093 0.97 7 8 0.00078 0.056 14.0 1.2 1 23 2099 2123 2099 2123 0.91 8 8 0.0025 0.18 12.5 2.7 1 23 2144 2168 2144 2168 0.92
Sequence Information
- Coding Sequence
- ATGACGCTacagcacagcagcagcaacaacagcagcagcaacaacaacaacaccagcagcagcaatatcaacacaaacaacaacaatagcaacgaTGATGTCGCCgccgtagcagcagcaacaattgtcgATTGGAAAAGCTCGAACAATTTGCGGTATTTGCACAAAAAGTTCAAGCGTTTGGCCAGCAccacagaaacagaaacagaaaccgaAGCGAACGAAACACTGCGAACAACATCGCTGTCGTCGAACAGCTCATTGTCGCCGCCTCAGTTGCCGCTGCTCAACGGACACGAGTTCGCGactgccaacagcaacagcaacaacagtcatGAGGAGAGTCACAGcaaaaatgctgctgctgctgttgctgttgctggtatGCCACGGACTCGCACGCCcctcagcaacagcaacaatatcaGCAATTATGCCAGCAATGCAACATTGTCGCCAGCAACATTTgcacagcatcagcaacagacGCAGccaacgacagcagcaacatatgCCACAAGCACGCCATCAACAACATatgtaacagcagcagcagccagcacgccagcaacaacatatgtgacagcagcaacaacagccacgtcagcagcaacatatgtgacagcagcaacagccacgccagcagcaacatatgCCGCAAgcacaccagcaacaacatatgtaacagcagcaacagccacgccAGCAACATATGCCACAGCTACGccaactgcaacagctgccacagcaactgcaacaggtCGCTATGTCTGCCAGTATTGTAATCTAATTTGTGCCAAGCCCTCGGTGCTGCAGAAGCACATTCGTGCCCATACGAACGAGCGTCCTTATCCCTGCGAAACGTGCGGCATTGCCTTCAAGACGAAGAGCAACTTCTACAAACATTGTCGTTCGCGTTCGCATGCGGCGCGCATGCGCGGATTGGATGTGCCGGCCCACGAGGCGGACGGACTGTCCGATCAGGACGGCGATGGGGatctcagcaacagcagctctgAGCTGCTAAGTGTGGAAATTctAAGTCGCGCTGATTCGCCATTTGATGAGCAGTCGTCGATTGCCTCGCCCACGCCCTCGCCCTCCACACTGTCGGCTGCGAAGAGCGCGTATCTGCAGCAGCCGCCATTGCCGCAGCACATGCAACAGTTGCCGTTGGGCTCGCCTGCTGCTGGCACCTTGCCGCCAGCAACAGTTGAGAATTTGCACTCGGCGACGGCGCAGCATCGGCAATCGATTGACTACAAGCCATACAAGCCGAAATTTCACAATGCAGCGCTCTATGCGCCGGGCAGCCTCAAggaccaacagcagcaacagcagcagcagcagcagcaccagcagatgctgcaacagcaacagcagcaacagaagctGCCGCAGCCATTGCTCGTGCATCCCACGCTCTCGCCTAGCACTCAGCTGAAGCTCAACAATCACATCAACTCGCatcagttgcagctgcagctacaacagcagcagcagcagcagcagcagcaccaacagcagcagcaacagttacaacaacagcagttgcACGCACAGCAATCattgctgctggcagctgctgctgctggcaatcCCGTTGCACTGCCTCCGCCGCCAATGCCCACGGGCGTCTACTATTTGGGACAGCCGCCATATTACAAtccgacagcagcagcagcagcaatgcatCAGCATGCGTTTGCCTTTCAGCAGCTGCAATATCAGCAACattttcagctgcagcagcagcagcaacatctgcaacagcagcaacattcgCCTTTGCTCAAAGCGCCGccgccacagcaacagcaacagttgccgccgccgccaccacagcagcatcaacagcagcagcagcagccGCTGCCACGCTCAAATAgtcaacaggcagcagcagcacctgccacgcccacacctgGTGGCAATCTAAGCAGCTTTGCCAGCGGCATGCAAGTGaatGTGGAGAAGGTGCAGGAGCACATATCAAAGTTGATCTCACAGAACGAAGCCATCGTGGAGAACAAGGAAATATTGCTGCAAAAGAAATATCCCAAGCAGCTGAATCGTTCGCGCAGCTtcaacaatgccaacaacaacaacagcaacaacaacagcagcaacagcagcagcaacaacaacaacaatagccagCAGCTGGGCGAGGCGAAAGTGAATCTGGCACAGAGCATagtacaaaagcaacagcagcagcagcagcagcagcagcagcagcagcagcaacaggtgcaacaattgcaacaaatgcaacacatacaacaacaatatatgcAACAGAAGCCAACGCTGGAGCAACCTGTCAATGGGCTGCtcaaacgcagcagcagcagcaatgcctATGCAGGGCTTaaagccacgcccacgcaaaatgtgaaattgccgccgccagcagcaacattgcAAATGTTGCACTATCGTCAGGATCCAGCGATGCCTTTAACTAAActcgagcaacagcaacaggtgACGCCCAATCATCAGCCTTTGAATCTGTCCGCCAAAGCAAAGCCGCCACAAAAgctagcagcaacaacagcagcaacaacaactggcacaacaacaacaacagttgctgtaGTTAAaccaacaacagttgctgccgcaCCGCCAAACAATTCGATAATCAAAAATCTATTGCTCAACGCACGCGGCCTGGCCGTGCCCATTGGGGAGGGCGACGACGCCGTCTACTCGTGTCCGATCTGCGCGAACGAGTTCCGCAGCGCGGACGAGTTGAAGCAACACAACAGCACCTATTGCCAGGACGCCAGCAGCAGTGCGCCCATCAGTCCCGCCTCCTCGCCGAGCAGCAAATACTTTCGCTCCAATTCCATATCGTTCAGCCTGCCCGAGCTCCAGTCCCACATGGCCAACTCGAAGAATCCTTTGTCCTTGGCCAAGTTGGCCAAGTTGTCCTGGTACCAGCTCAAGACGAAGCCAAGCAGCTTGGTGCTCAGTCGTCTGAGTGCAGCGCAGTCGCCGGcgcgaacaacaacagcagcaacagcagttgcagcgacaacaactgctagcagcagcaactacaacagcaacaacttgaCTCtgccagcaacagttgctgtcaGCATAGATGCCAGCAATGTTGCCCTACGCTTTGTGGACGCACCTTTGCCGTCACCTGGCCCGCTGCTAGGCAAAACCGCTCTAGTGGACTATGCGGCCCCCAGGAAGGCGCCCGACGCCCAAGTTGTCATCACGAAAATGCACGAGGATCGCCTGGAGAACATCATAGTCGAGAGTTCGGCGAAGCGCGCCAAGTTGAGCAACGACTCGGCCTTTGCGCTGCCGGCAACAGGTGTGCAGTTGCtgttcagcagcagcaatcaggAGCTGGCTGGCAAAGAGGAGCGTCTGCGTCGCTTCACCTCCTCCGGCGGCTCCATGATACCCATCTCCGAGTGCCCCGAGCTGGACAAGAGTCCCAAGATGATAAGAACGCCCTTGCTCTCCGGCGGCAGCTTTCAGGAGATGTCGCCGCGTCTCAGCGAACCCAAGCCCAAGCCGGGCTTTCTACTaaacgccagcaacaacaacaacaacaacagcaacaacaacagcaaccagcAACATTTTCAGTTTCCGCCCATCAACTCGATAACTGCCTTCAATCCGCTGACGCTGCCCGCGCTGAGCGAGTCGAGCGGCAGCAAGGCTATACCCTATGTGCCGGGCATACCGGGACCGGGTAgcctggcgctgctgccgccgccgccgcaacAGTTGCTGCGACGCCCAAGCCCAAATCCCAATCCTCTCCAGCTGCCCGTGGAGACTCCTTTGAAGAAGTCGCTGTCGCCTTTTGGCGGCGTACAGAATTTGCCCAGCGAATTCAGTCGACAGCCGCCGACGCCAGCGCAACGCAACGCGCTCCAAtggcagagcagcagcagcaagccagcagcaactgttgctgttggcaatGGCTTCAACTTCTTGCGCATGGCCGACAATGTCAAGGAGCAACAGGAAGTGAGGCATTTCATATTCGATGCGCTCCATGTGGAAACACCTGAAGTggaggcagcaacaacagcagcagcagcagcagcaacagttgctggtacagcaacaattgctgcgaCAACTGCAACGAGCGCTGCGAGTAAATCGAAATTTCTGCGTCCCACCAGCTTGCCTTTGAAGCCGGGCACCTTTACGCCCAAGCGACATCACGGCATCACACCGACTGCAAATACCCTGCCTTTGATCTCGCCCGAGACGCCGCGTCCCTCGAAGTCGTGCGTCCAGCTCTATCTGAACGGACACGCCTACACCTACCTGGGCCTCAAGTGCAGCACCAAGATGTTCTACTGTACAGTGAACTGTCCGCAGCCGTCGTACGTCGCCGGCATGCACAAGCTCTCCATGTACAGCGTGTGGCAGGTGTGCGAGGAGAACCAGCCGCATCCGCTCGGCTTCAAGCCGAAGCAGGTGATGTCGCTCTACGACTCGCGCCAGAAGCTCTTGGGCAGCAACACCACAGTGGTGCAGGCCGGCGGCTCCACGCTCCACTACTCCCTCGTCAGCTCCCAGCAGACcatcagcagctgctccaccATTGTGAACACTCAAAGCAAATTCTATCAGCATCAGACGAAGCAGACGCCGGCAATCGGCGCCCTCAGCGAGGCGAATGTTGCCGCCAAGGCGAACGAGGAGGCGGCCAAGAAACTGGAGTCGGGTCAACTCCTGGTCGGTGGCTACGAGTCCAACGAGGACTATACCTACATACGTGGACGTGGGCGTGGTCGCTACGTCTGCTCCGAGTGTGGCATCCGCTGCAAGAAGCCCTCGATGCTCAAGAAGCACATACGCACGCACACGGACGTCAGGCCATTTACCTGCAGCCACTGCAGCTTCAGCTTCAAGACCAAGGGCAATCTGACCAAGCACATGCAGTCGAAGACTCATTTCAAGAAATGCATTGAGCTGGGCATCAATCCGGGTCCGATGCCGGCGGATGGCGAGTTCCTCGATGTGGATGTGGAATTCGATCAGCAATCCTCGACTTCAGCTGGCGGACGCACCTCATCCATGGCTGGCGACTCGGCAGACTCTGATGATTACAGCGACAATGAATCCGAGAGTAGTGATACAGATGAATCGAAATCCCGCTTGAAGGAGCACGAGGCAGCGCGTGGCTTGCTTTCGCTTTCGATGACTCCGCCCATACCACAAAGTGTTTCGCCTTATCCCGCACAGCTGGAGGCGCCTCTGCCCGTGGGCAGTCCAGCGAATAGTATTGGCTCTGGCGGTGGGTCGTCGCAGCCGAAGCGGCAGGTGTGCTCCTTCACCTCGCCCAAGCCGCCCTTTGACTACCAGAAGCAGGAGCAATACTACTCGAATCCCGAGGAGTCCAAGCCCAAGCGCCAAGTGCCCACAGACGAGAGCAGCGCCCCCATGGACCTGACCAAGCcgcgacagcagctgcaacagatTTCGCCCGTGGAGCTGCCCAAGTCGCAGGCGCAGCAGATGCGCGACGTCATCTTTGGCGCCGGCAACAACGAATGCGGCTTCATGAAGACCCTAATCTCGGTCTCCGACAAGGTGCGCATTTCCGCCGAAATGGAGGAGCAGGCGAAGCGCGAGAGCGAGGGCGAAGATGTGCTGCTGCAGACCTACATCAAGGAGCAGGCGCTTCACAATGCCAAGCGCAAGCAGAGCTTGTACAGCTGCAGCTACTTAATGACAACAactaccagcagcagcagcagcagcagcaacatgcccattgtcagcagcagcagcagttgccagcagcagaagcCTAACTTGTTCAATGAGCTGCCTAGCATCGAGGTGCATGAGCCCGAGGCTGAGCAGCTCGAGAGCGAGGAGGAGCAACTGCCGGaggtgacaacaacaacaattgctgttAGCCAGgagccggcagcagcagcagcagcaactcctcCACACAATGCAAATTTGCCTGCTGCTGTGCAGCAGCCAGATGCAACAGACTTTAAAGGTGTcctaagcagcagcagcaacattcaagcaacagcagcaacagcagcaactgtagcAAAAGTGACAGCAACTGAGGAGCCCGCACCggcggcaacagttgctgctgtcacAGCAGCCACGAGCAGCAGCTATGTGCCCGCGCGTATTGTGGCCGCGCCACCTCTGCCCATCAGCAGCGATGCGCGTCCCACCTGCCTGCTGTGCAGCAAGACGTTCCAGCGGCAGCACCAGCTGACGCTGCACATGAACATCCACTACATGGAGCGCAAGTTCAAGTGCGAGCCCTGCAGCATCTCCTTTCGCACGCAGGGACACCTGCAGAAGCACGAGCGCTCCGAGGCGCACAGGAACAAGGTGATGATGACCTCGACCTTTGGCGTGCCGACGACCTCGAATCCGAGGCCTTTCGAGTGCACCGACTGTAAGATTGCCTTTCGCATCCATGGGCATCTGGCCAAGCATTTGCGCTCCAAGACGCACGTCCAGAAGCTCGAGTGTCTGCAGAAGCTGCCCTTTGGCACCTACGCGGAGATCGAGCGGGCGGGCATAAGTCTGACGGAGATCGATACGAGCGACTGCGAGAACTCGCTGATCTCGCTCAAGCTGCTCGCCCAGAAGCTGCTCGAGAAGGATCCCAATAAGCTGAGCGGCTACACCACGCCCTCGGGCATGCTGCAACTGGCAGGAGGCGAGACGCCAGCCGCGAACCAGGACAGCGCCTCGGAGGACGGTTTCAGTGCGGCGAATAGTGCGGCTGCCTCAGCGATTGCCTCGCTGGACAACGACAGCGCGGGGAATACGCCACAGCGAGCCAGCTCCATGTCCGAGGACGAGGCGCTCACAAATGGCCTCAGCCATGGCCAGAGCCTGAAGCGCCGTCTGCCAGGGAacagcttcagcagcagcaacggcgacGAGAGCGACAATCCGCTGGAGACGAGCGAGAAGCGTGCGAGGAGCAATACGAATGAATTGGCTTTGCCTGCTGTCGGCAGCAACTGA
- Protein Sequence
- MTLQHSSSNNSSSNNNNTSSSNINTNNNNSNDDVAAVAAATIVDWKSSNNLRYLHKKFKRLASTTETETETEANETLRTTSLSSNSSLSPPQLPLLNGHEFATANSNSNNSHEESHSKNAAAAVAVAGMPRTRTPLSNSNNISNYASNATLSPATFAQHQQQTQPTTAATYATSTPSTTYVTAAAASTPATTYVTAATTATSAATYVTAATATPAATYAASTPATTYVTAATATPATYATATPTATAATATATGRYVCQYCNLICAKPSVLQKHIRAHTNERPYPCETCGIAFKTKSNFYKHCRSRSHAARMRGLDVPAHEADGLSDQDGDGDLSNSSSELLSVEILSRADSPFDEQSSIASPTPSPSTLSAAKSAYLQQPPLPQHMQQLPLGSPAAGTLPPATVENLHSATAQHRQSIDYKPYKPKFHNAALYAPGSLKDQQQQQQQQQQHQQMLQQQQQQQKLPQPLLVHPTLSPSTQLKLNNHINSHQLQLQLQQQQQQQQQHQQQQQQLQQQQLHAQQSLLLAAAAAGNPVALPPPPMPTGVYYLGQPPYYNPTAAAAAMHQHAFAFQQLQYQQHFQLQQQQQHLQQQQHSPLLKAPPPQQQQQLPPPPPQQHQQQQQQPLPRSNSQQAAAAPATPTPGGNLSSFASGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNNNSNNNSSNSSSNNNNNSQQLGEAKVNLAQSIVQKQQQQQQQQQQQQQQQVQQLQQMQHIQQQYMQQKPTLEQPVNGLLKRSSSSNAYAGLKATPTQNVKLPPPAATLQMLHYRQDPAMPLTKLEQQQQVTPNHQPLNLSAKAKPPQKLAATTAATTTGTTTTTVAVVKPTTVAAAPPNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKQHNSTYCQDASSSAPISPASSPSSKYFRSNSISFSLPELQSHMANSKNPLSLAKLAKLSWYQLKTKPSSLVLSRLSAAQSPARTTTAATAVAATTTASSSNYNSNNLTLPATVAVSIDASNVALRFVDAPLPSPGPLLGKTALVDYAAPRKAPDAQVVITKMHEDRLENIIVESSAKRAKLSNDSAFALPATGVQLLFSSSNQELAGKEERLRRFTSSGGSMIPISECPELDKSPKMIRTPLLSGGSFQEMSPRLSEPKPKPGFLLNASNNNNNNSNNNSNQQHFQFPPINSITAFNPLTLPALSESSGSKAIPYVPGIPGPGSLALLPPPPQQLLRRPSPNPNPLQLPVETPLKKSLSPFGGVQNLPSEFSRQPPTPAQRNALQWQSSSSKPAATVAVGNGFNFLRMADNVKEQQEVRHFIFDALHVETPEVEAATTAAAAAATVAGTATIAATTATSAASKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMSLYDSRQKLLGSNTTVVQAGGSTLHYSLVSSQQTISSCSTIVNTQSKFYQHQTKQTPAIGALSEANVAAKANEEAAKKLESGQLLVGGYESNEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCSFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDVEFDQQSSTSAGGRTSSMAGDSADSDDYSDNESESSDTDESKSRLKEHEAARGLLSLSMTPPIPQSVSPYPAQLEAPLPVGSPANSIGSGGGSSQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRQVPTDESSAPMDLTKPRQQLQQISPVELPKSQAQQMRDVIFGAGNNECGFMKTLISVSDKVRISAEMEEQAKRESEGEDVLLQTYIKEQALHNAKRKQSLYSCSYLMTTTTSSSSSSSNMPIVSSSSSCQQQKPNLFNELPSIEVHEPEAEQLESEEEQLPEVTTTTIAVSQEPAAAAAATPPHNANLPAAVQQPDATDFKGVLSSSSNIQATAATAATVAKVTATEEPAPAATVAAVTAATSSSYVPARIVAAPPLPISSDARPTCLLCSKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLAGGETPAANQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDEALTNGLSHGQSLKRRLPGNSFSSSNGDESDNPLETSEKRARSNTNELALPAVGSN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -