Basic Information

Insect: Drosophila gaucha
Gene Symbol: ZNF639
Assembly: GCA_035045545.1
Location: JAWNOY010000433.1:166220-168276[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.019 1.4 9.7 0.3 3 23 295 316 294 316 0.91

2 10 0.00016 0.011 16.2 0.5 6 23 325 342 325 342 0.99

3 10 9.6e-06 0.00068 20.1 0.3 1 23 348 371 348 371 0.98

4 10 0.00013 0.0094 16.5 0.5 1 23 383 405 383 405 0.98

5 10 0.00032 0.023 15.3 7.7 1 23 412 435 412 435 0.96

6 10 1.3e-05 0.00096 19.6 1.8 1 23 441 463 441 463 0.96

7 10 0.1 7.4 7.4 0.5 2 23 472 493 471 493 0.96

8 10 9.4e-05 0.0067 16.9 3.5 3 23 500 521 498 521 0.95

9 10 2e-07 1.4e-05 25.3 0.7 2 23 528 549 527 549 0.97

10 10 0.0002 0.014 15.9 4.4 1 23 555 578 555 578 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.019	1.4	9.7	0.3	3	23	295	316	294	316	0.91
2	10	0.00016	0.011	16.2	0.5	6	23	325	342	325	342	0.99
3	10	9.6e-06	0.00068	20.1	0.3	1	23	348	371	348	371	0.98
4	10	0.00013	0.0094	16.5	0.5	1	23	383	405	383	405	0.98
5	10	0.00032	0.023	15.3	7.7	1	23	412	435	412	435	0.96
6	10	1.3e-05	0.00096	19.6	1.8	1	23	441	463	441	463	0.96
7	10	0.1	7.4	7.4	0.5	2	23	472	493	471	493	0.96
8	10	9.4e-05	0.0067	16.9	3.5	3	23	500	521	498	521	0.95
9	10	2e-07	1.4e-05	25.3	0.7	2	23	528	549	527	549	0.97
10	10	0.0002	0.014	15.9	4.4	1	23	555	578	555	578	0.96

Sequence Information

Coding Sequence: ATGATCTGTCGCTTgtgtttaaaaaacataaacgcAAACAATGCCGTCTACCTGTTCGAAACGAACGAGACGCTGGCAGAATCCTCGCTGCTCAAAATGATAGCCAAGTTTCTGCAGCTCGAGATAACGCCCGATGACAATATCTCGACAAACATTTGCCACGAGTGCTGCGAGCACTTGGAGGATTTCAACAACTTCTGGCAGCTGGTGGAGCAAAAACAAGGAACACTTAATAAGGAGTTCCTCAACGTGGACGTCGACTGTGTCGCCCTCAAATGGACCGGCGGCATCGATGTCGACGTCAACATTGATGAGCTGCCCCTAGTTGCCGACGAGATGGACGAGAAGCCATTGGACATACACAATCTTGGCCTCCTCGGCAGCGTACTCGACGTGAATGTGGACAGCGTGGaggtgccgctgctgcagaCTGACTCCAAGCCGAAACAGTTTCAGACTGAAAAGTTTCTACAGCTGCATGCACCCGACTCGAGCGATGAGGATGCAAACGacaacgtcgacgtcgaccAGAAGCCCTTGATACATGACACCGACACCGGCGATGCCTCCACAGATGAAGATGATGACGAAGTGCCACTGGTGAAGCTGCAACACAAACTGAAGCCGAAGCTGAAAGGACGACGGGCAATCGCAAGGCGAAACAAGCGAACGCTTACGCTCGCCCAGGAGCTGGACCAGCTGCTGGACGAGAGTGAACTCGGTGGCAGCAAATCGCGACGGAAAAAGGCGACAAACAATGCGCCGACCGATGTGCAAAAAAGCGAGCTGCAGGCGGCGCTGGAACGCAAGCCCAAAGGCTGTTCCCGTGCCCAGCTGACGAAGCGCTACGAAGAGGCGATCGCCAGCTACATGAGCGCCGACTGTGATCTCTGCGAGTACAGCACCAAGTACCTGTCCCAGCTGAAGGTCCACTTCCTGGAGGTGCACCAGCGCGATGCGTACTTGAAGTGCTGCAACAAGGTCTTCAATCGCGCCTCCAAGCTAATGGATCACATACGCAAACACATCAATCCCAAGCTCTTCACCTGTTCCATTTGCAATAAGTCCCTCAACTCGCAGGACTACCTGGCCACCCACATAGAAACGGTGCACAACAAGGTCGCCCAGATTGGCAAGGTGCTAAAGTATCCCTGTCCCAAGTGCGAGCGCACCTTCAGCAGCGAGCGCCGTTTGGGCAATCATCTGCTCAAGCACGACACGGACCAGTTGGAGCACAGCTGTCACATATGCCACAAAAGcTTTGCCAATGTGCATCGACTGCGACGGCATATACAGTCGATACACGAGGACCTGCATCCGCATGTCTGTGATATATGCGGCAAAAAGTTCAAGTTTAAGCCCTCTTTCGAGCGGCATCTGCTGGAGCATCAGGGCGTTGTGGCCCCGGCCATGGAGTGCCCCGTCTGCGGTGTCTGGCTGAAGAACGAGCACAGCCTGAGGCTGCACCGATTCACGCACGACAGCACCGACACCAACTGCCCGCACTGCTCGAAGACGTGCAGCTCGCGCACGGCGCTGCGCGCCCACATCAAATACGCCCACAAGCTGACAACGAATCTGCAGTGCACGTACTGCGAGAAGAGCTTTAAGCAGCAGCGCAATCTCGAGGAGCACATGGCCATACACACGGGCCTGCAGCTCTACAATTGCCCCCACTGCCCCAAGGAGTGCCGCAGTCGCTCCAACATGTATGTCCACATCAAGCAGCGGCATGCGGACGAGTGGCTCAAGGCCAAAATGGCCCGCTCCCACAATCCCCAATTCAAGCCACCGCACGCCTAG
Protein Sequence: MICRLCLKNINANNAVYLFETNETLAESSLLKMIAKFLQLEITPDDNISTNICHECCEHLEDFNNFWQLVEQKQGTLNKEFLNVDVDCVALKWTGGIDVDVNIDELPLVADEMDEKPLDIHNLGLLGSVLDVNVDSVEVPLLQTDSKPKQFQTEKFLQLHAPDSSDEDANDNVDVDQKPLIHDTDTGDASTDEDDDEVPLVKLQHKLKPKLKGRRAIARRNKRTLTLAQELDQLLDESELGGSKSRRKKATNNAPTDVQKSELQAALERKPKGCSRAQLTKRYEEAIASYMSADCDLCEYSTKYLSQLKVHFLEVHQRDAYLKCCNKVFNRASKLMDHIRKHINPKLFTCSICNKSLNSQDYLATHIETVHNKVAQIGKVLKYPCPKCERTFSSERRLGNHLLKHDTDQLEHSCHICHKSFANVHRLRRHIQSIHEDLHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECPVCGVWLKNEHSLRLHRFTHDSTDTNCPHCSKTCSSRTALRAHIKYAHKLTTNLQCTYCEKSFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQFKPPHA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610817;
90% Identity: iTF_00531107;
80% Identity: -