Basic Information

Insect: Drosophila gaucha
Gene Symbol: ham
Assembly: GCA_035045545.1
Location: JAWNOY010000465.1:3065343-3089868[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.59 42 5.0 0.0 2 21 340 359 339 362 0.87

2 9 0.0088 0.63 10.7 0.1 1 23 369 392 369 392 0.92

3 9 1.8e-07 1.3e-05 25.5 1.7 1 23 398 421 398 421 0.96

4 9 3.5e-07 2.5e-05 24.6 1.5 1 23 427 449 427 449 0.97

5 9 8.9e-05 0.0064 17.0 3.8 1 23 455 477 455 477 0.97

6 9 0.002 0.14 12.8 2.0 2 21 485 504 484 505 0.94

7 9 6.9e-09 4.9e-07 29.9 1.3 1 23 1001 1023 1001 1023 0.99

8 9 3.7e-07 2.6e-05 24.5 0.9 1 23 1029 1052 1029 1052 0.97

9 9 4.7e-05 0.0033 17.9 6.8 1 23 1058 1080 1058 1080 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.59	42	5.0	0.0	2	21	340	359	339	362	0.87
2	9	0.0088	0.63	10.7	0.1	1	23	369	392	369	392	0.92
3	9	1.8e-07	1.3e-05	25.5	1.7	1	23	398	421	398	421	0.96
4	9	3.5e-07	2.5e-05	24.6	1.5	1	23	427	449	427	449	0.97
5	9	8.9e-05	0.0064	17.0	3.8	1	23	455	477	455	477	0.97
6	9	0.002	0.14	12.8	2.0	2	21	485	504	484	505	0.94
7	9	6.9e-09	4.9e-07	29.9	1.3	1	23	1001	1023	1001	1023	0.99
8	9	3.7e-07	2.6e-05	24.5	0.9	1	23	1029	1052	1029	1052	0.97
9	9	4.7e-05	0.0033	17.9	6.8	1	23	1058	1080	1058	1080	0.98

Sequence Information

Coding Sequence: ATGTTATTCGATCGTTATATTATATCAGGCTCTAACGGCGACGACTACGATCCGAGCGTCGTGCGccaccatcatcatcaccacCATCTGGATCTCAGCAGTGGAGCGCCGGCTTTTGGTCCGCTGCCGCCGGCGCATCTAACCTCCAGCCAGGTGCGGCCAGAGGAGACGTTCGCCCGCCATCTGCCGCCAACGATATCCCCGCCACCCGCAGCGCTGcttcatcagcagcagcagcatcagcagcagtcgccgcatttgccgttgcagttgcagcaacagcggctGCAGCGTTCGCCGCCCGCCTCCCTATCTGCCTCCGGCTCCGGCGCCAATATGGAGCACATCATCAATGACAAGGCGCAGGCGCTGCTGCTCGAGATGGCGCGCCTGCGCGAACCCGTCTGTGATCTGGACATCCGTGATACTGGCGTCTATGCCAAGACCCATTTGCCACGCGGCACCCGCTACGGACCCTTTCCCATGCGTCTGTGCCAGCAGCCCAGCGATCACCATCTGGCCTGGGAGGTAATTGCCGGCCCGCTGTTCCATGGCTGGCTGGAACCCTCAGCGGATGTGGCCACATGGCTGAAAAAAATACGCTCCGCGCAGTCCGATGAAAGTGAAGAGGCTAATTTAAGGAATTTCATAACCGCCGGCTATCTGTGGTACGAAACGAAGCGCGATGTCAATGCAGGCGCTGAGATCGTGGTCGATGCACGTTCCAAAACTCCCTACGATATCAGCGATAGCTTTATGAATGGCAGCGGATCGGGTGGctgcaacagtagcagcagcgccgtagcaacagcagcggcagcaacagcggcagcagcagcagccgccgctgcagcagcaacagccatggcagcagccaacaacaacaacaacgatgatCGCAGCGATCGTGATAACGGCTTTTATAGCGGAGACGAATTTTCCAAGGAGAAGAAAAACTCATCGTTAAACAGTCAGGGCGACAACGATTTCACAGACGACGAGAACGGTTTCGATATACGCTGTGAGGTCTGTGATAATGTCTATACGGATTTAGAACGCCTGGACGATCATCTGGTGGGCGCACATCACTTCAAGCGCGGCGAATTTCCCTGCGAGCTCTGCGCCCAACGTTTCTCCCATCGTCCATTGCTAATCAAACACGGAGCGATCgctcataataatataagGAAATATTCCTGCGAGAACTGTTCCAAGGTATTCTGTGACCCATCGAATTTACAGCGTCATATTCGCGCCTATCACGTCGGCGCTCGCAGTCATCCGTGCCCGGAGTGCGGTAAAACATTTGCCACATCGTCTGGCCTGAAGCAGCACCAGCACATCCATTCCTCGGTCAAGCCGTTCGCCTGCGAGGTGTGCTTCAAGGCCTACACACAGTTCTCGAATCTGTGCCGGCACAAGCGCATGCACGCCGACTGCCGCATGCAGATCAAGTGCAAGAAGTGCAACACGAGCTTCAGCACGGTCACCTCGCTCTCCAAGCACAAGAAGTTCTGCGACAGCTCCGACAGCTTTCGCAGCAGCCAACAGAgtcggctgcagcagcagcagcacgcgTCGCATCAGCATTCGCATcagcattcgcattcgcattcgcattcgcattcgcactCGCAGCAGCCGACGCCGCCGCAGCTTCTTTTGCCGCCAGGTGCACATCAGCGACTCGCTgtagccgccgccgccgccgcagccagtagcagcagcagcagcaacaacaacgacacaGCCGCCATGGCCACGCCCCCGAATCACATATTCATGATGCGTCCCACGCACTCATTCTTTCCGGGCTTCCCCCACTACGGACTGCCCAACTTCTTTACGCCCGGCCTGCCGCAGGCGGGCAACTTTCCTCTGCCGCCGCACATGTTTCCCAATCCCCAGCTGGGCGACATGGGTCGCGGCCTGGTGCCGCCGCTCGTCTCTCCAAACTCTGccttccagcagcagctgcaggcggCCATGAGCCTGAAGTCCGAGTCGCCGCATGTCAAACGCGAGTCCGGCACGCCGGAGCGCAAGTGCATCAAGGCCGAACGGCAGCCAAGCGACgatgaggaggaggatgaGTCCAATTCCTAtgaccagctgcagctgaagctggaCTCCAGCAAGAAGTCGAGCAAGCTAAAGTCGGAGTTCAAGCGGGAAACCAACTGCGCACAGTCAGCACAagataatgatgatgaaaatgacaatgataatgacaatgataatgacaatgacaatgacaatgataggAAATCCATAGATATAATGAGCACACCACCGCCGGCAGAGACGGAGCTGCAGCCGGAGCTGGATAAGAGCAGCGCCGATCTACTGCCTCTGGATCTGTCCATCAGTCGCAAGCGCCGCAGCTCATTGTGCACGACCAGCACGCCCGTGCCGCTGGCCATATCGCTGTCCAGTCGCACGCCCACGCCCGAGCTGGACGCAGCGGAGGCAGCTGCCGGGCAGCCGCCCATCAAGCTGCTGAAGCACAGCTCCGGCGAATCGTCCACCTCGCATCAGTCCTACAAGGGCAGCAGTCCCACGCCGAGTGTTAGCGCCTCGCCTGGACCCAcgccctcgccctcgcccCCCATCAGCACGGGCGGCGAGCTGAGCAGCATGTCCGAGAGCGCGGCGTCCGCTGCCGTCGGCGCTGCaacggcggcggctgctgctgcatcggCAATGGCCTGTCCGCGGCAGCTGCAtccacagctgctgctggaggagCTGTATCGCTCGCGCTTCAATACGCCACCGTTTCATTTTTTAGGCCAAATGGGCGGACGGCCAGGTTTTGAGCCACTCAAATCGCCGGCTGCTGTcatcagcagcggcagcagctcgcGTCATCTGCCGTTTCCGCCCGAGCACAATTTCCATGAGGCCCTGCGAGCCGCTGGGCTGGCTGCCGTCGCCgccaatgcctgcagcagcgGCGCCAGCGTCGTCAGCGCGAATGGGGGCAAGCTCAAGGATCGCTACACCTGCAAGTTCTGCGGCAAGGTGTTCCCGCGCTCCGCCAATCTCACCCGGCATCTGCGCACCCACACCGGCGAGCAGCCGTACACGTGCAAGTACTGCGATCGCGCCTTCAGCATCTCCTCGAATCTGCAGCGACATGTGCGCAACATTCACAACAAGGAGCGTCCGTTCCGGTGCCACATGTGCGATCGCTGCTTTGGCCAGCAAACGAATCTCGATCGGCATCTGAAGAAGCACGAGGCGGATGCGGGTGGCTTTGAGTACAACGATTCGCCCAGCTCCAATGAGGCGAACGATCGGGACGAGGCCTGCTTCGACGACATACGCTCCTTTATGAAGCGCGTCTATACGCCCACAAGTCTGGGCGGGGCTGATGGGGATACCGAGGAGTATGCGGGCAGCGATGATCAGTTGTCCGTCTCGACGCGTCAGTCTGTCAACTTTGACAAGGAGCTGCTcgccaatggcaacaacaacaataacagcaacaacaacaataacagcaacagcagcagcaacaacaacaacactagcaacaacaacaatcagacAGGTCTGGGCGAAACAATCGCCGTCAGCACCTAA
Protein Sequence: MLFDRYIISGSNGDDYDPSVVRHHHHHHHLDLSSGAPAFGPLPPAHLTSSQVRPEETFARHLPPTISPPPAALLHQQQQHQQQSPHLPLQLQQQRLQRSPPASLSASGSGANMEHIINDKAQALLLEMARLREPVCDLDIRDTGVYAKTHLPRGTRYGPFPMRLCQQPSDHHLAWEVIAGPLFHGWLEPSADVATWLKKIRSAQSDESEEANLRNFITAGYLWYETKRDVNAGAEIVVDARSKTPYDISDSFMNGSGSGGCNSSSSAVATAAAATAAAAAAAAAAATAMAAANNNNNDDRSDRDNGFYSGDEFSKEKKNSSLNSQGDNDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFPCELCAQRFSHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCKKCNTSFSTVTSLSKHKKFCDSSDSFRSSQQSRLQQQQHASHQHSHQHSHSHSHSHSHSQQPTPPQLLLPPGAHQRLAVAAAAAAASSSSSSNNNDTAAMATPPNHIFMMRPTHSFFPGFPHYGLPNFFTPGLPQAGNFPLPPHMFPNPQLGDMGRGLVPPLVSPNSAFQQQLQAAMSLKSESPHVKRESGTPERKCIKAERQPSDDEEEDESNSYDQLQLKLDSSKKSSKLKSEFKRETNCAQSAQDNDDENDNDNDNDNDNDNDNDRKSIDIMSTPPPAETELQPELDKSSADLLPLDLSISRKRRSSLCTTSTPVPLAISLSSRTPTPELDAAEAAAGQPPIKLLKHSSGESSTSHQSYKGSSPTPSVSASPGPTPSPSPPISTGGELSSMSESAASAAVGAATAAAAAASAMACPRQLHPQLLLEELYRSRFNTPPFHFLGQMGGRPGFEPLKSPAAVISSGSSSRHLPFPPEHNFHEALRAAGLAAVAANACSSGASVVSANGGKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCHMCDRCFGQQTNLDRHLKKHEADAGGFEYNDSPSSNEANDRDEACFDDIRSFMKRVYTPTSLGGADGDTEEYAGSDDQLSVSTRQSVNFDKELLANGNNNNNSNNNNNSNSSSNNNNTSNNNNQTGLGETIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00568407;
90% Identity: -
80% Identity: -