Dgau001366.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila gaucha
Gene Symbol
-
Assembly
GCA_035045545.1
Location
JAWNOY010000025.1:6719346-6721410[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00029 0.021 15.4 5.0 2 23 137 158 136 158 0.98
2 9 6.4e-07 4.6e-05 23.8 3.1 1 23 164 186 164 186 0.99
3 9 4.2e-07 3e-05 24.3 1.0 1 23 192 214 192 214 0.99
4 9 1.2e-05 0.00083 19.8 3.5 1 23 282 304 282 304 0.99
5 9 1.1e-06 7.8e-05 23.0 0.9 1 23 310 332 310 332 0.98
6 9 1e-06 7.2e-05 23.1 5.8 1 23 338 360 338 360 0.99
7 9 1.1e-05 0.0008 19.8 1.2 3 23 472 492 470 492 0.98
8 9 1.8e-06 0.00013 22.4 0.5 1 23 498 520 498 520 0.99
9 9 1.2e-07 8.9e-06 26.0 2.2 1 23 526 548 526 548 0.98

Sequence Information

Coding Sequence
atgcatttgaaccATGCGACGGCCGCGACAGCTGCCATGGCCAACTATCAGCACTATGCGCCTGCACAGCTTGCCACGCATAGcgttggcggcggcggtggtggtggcggcggtggcggctcCGGTGGCGGTGGCATCGGTCCGAACAGCTTACAGCAGCCAACGACTATTGCGAGCCTGCAGCAGAGCCCCTTTGCCCTACATCAATTGACTGCCGTGCAGGCCATACAGCATCCCACCCATCAAGCCATGCTGCATCCACAGCATCCGCTTGTCCACCTGCTCGACATCTCGACGACCACAACGAACAGCGGTGGCAACCACACGCCCATATCGCCTATGAAACAGGAGGTCCAGAGCGTCATTAGCGAGGATGAGTCTGTGGTGGACGATCCGCGCAAGAAGAAACAGTGCCACGTGTGCAAAAACAAGTTCCGGCAGCTAACCACGTTACGCAATCATATGAAAATACACACAGACGAACGTCCCTACAAGTGCAAGCACTGCGACAAGGCCTTCCGCCAGATATCGACGCTGACGAACCATGTGAAGATCCACACCGGCGAGAAACCGTTCACGTGCAATATTTGCGCCAAAGACTTTCGGCAGCAGAGCACGCTCATAAATCACATCAAGACGCATAAGGCGGCTGAGTCAAGCACGCCGACGTCGCTACTCAACTATCAGCCGCCGTCCTCTTCCGGCAAGCATAGCCGTAAATCGCAGTCGAATCAGATGCACAACGcctaccagcagcagcatcagcagcagcgtgTACAAATCTCAAAGACTCTATATTCGGGCACCTACAGCTCGCCACAGGCGGAGGAGCTGGTGAAACCGTATCAGtgcactgtgtgcaagcgacgtTTCCCGCAGCTGAGCACGCTGCACAATCACGAGCGGACGCACATCGATCCTAAGCCCTACAAGTGCGAAACTTGCGACAAGTCCTTCAGCCAGCTGGCGACATTGGCCAATCACAAAAAGATACACACCGGCGATAAGCCATACACGTGTTCCTACTGCCACATGCAGTTCCGCCAGCAGAGCACGCTCACCAACCACATGAAGACGCACACACATCTctccagccagccagccacaGTCACAGCCACAGTGGATCACTCAGCCATGCCAGCGCCCCTTATTCCTGGCACGCAGCAACTGACGAGCGGCTTGCTACCGAACAACCTGCACAGCACAACGCCCAACATCCTGCAGCTGGACCATCATCCGCTGCTACACTTTCTCGATGGTAGCACAACAGTGAGCTCCGTGGTGGCCAGCAAtgtagcagcagcggcggcggccaaCACCAAAGTCGAGCACTATCAAAATACGCAGGGTGTTCGACTGAATGTGggcaatataaatatgttgaaGGGTGACAATCCGGATCGGCCGTTTGGATGTAGCGTCTGTCGGCGCTTCTTTTCGCAGCAGAGCACCCTGGTCAATCACATCAAAACGCACACGGGCGAGAAACCGTACAAGTGCAAGATCTGTGAGGTTAGTTTCCGGCAAGTGGCCACGCTCAATAACCACATGAAGATCCACACCGGAGAGAAGCCCTACAACTGTTCCTACTGTCCCAAGCAATTCCGACAAAAGAGCACGCTACAAAACCATTTGCGGGTCCACACTTGCTAG
Protein Sequence
MHLNHATAATAAMANYQHYAPAQLATHSVGGGGGGGGGGGSGGGGIGPNSLQQPTTIASLQQSPFALHQLTAVQAIQHPTHQAMLHPQHPLVHLLDISTTTTNSGGNHTPISPMKQEVQSVISEDESVVDDPRKKKQCHVCKNKFRQLTTLRNHMKIHTDERPYKCKHCDKAFRQISTLTNHVKIHTGEKPFTCNICAKDFRQQSTLINHIKTHKAAESSTPTSLLNYQPPSSSGKHSRKSQSNQMHNAYQQQHQQQRVQISKTLYSGTYSSPQAEELVKPYQCTVCKRRFPQLSTLHNHERTHIDPKPYKCETCDKSFSQLATLANHKKIHTGDKPYTCSYCHMQFRQQSTLTNHMKTHTHLSSQPATVTATVDHSAMPAPLIPGTQQLTSGLLPNNLHSTTPNILQLDHHPLLHFLDGSTTVSSVVASNVAAAAAANTKVEHYQNTQGVRLNVGNINMLKGDNPDRPFGCSVCRRFFSQQSTLVNHIKTHTGEKPYKCKICEVSFRQVATLNNHMKIHTGEKPYNCSYCPKQFRQKSTLQNHLRVHTC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00901644;
90% Identity
iTF_00559629;
80% Identity
-