Dgau006173.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila gaucha
Gene Symbol
-
Assembly
GCA_035045545.1
Location
JAWNOY010000129.1:4410832-4415484[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.0025 0.18 12.5 1.3 1 23 220 242 220 242 0.96
2 26 0.033 2.4 8.9 1.9 1 23 248 270 248 270 0.97
3 26 1.2 86 4.0 2.1 2 20 302 320 301 323 0.93
4 26 0.0048 0.34 11.6 1.5 1 23 400 423 400 423 0.93
5 26 0.59 42 5.0 3.3 2 23 434 457 433 457 0.93
6 26 1.8 1.3e+02 3.5 0.2 1 20 463 482 463 484 0.89
7 26 1.1 79 4.1 0.7 2 23 498 519 498 519 0.96
8 26 0.014 1 10.1 1.4 1 23 599 622 599 622 0.95
9 26 0.0071 0.51 11.0 0.2 1 22 631 652 631 652 0.94
10 26 0.006 0.43 11.3 4.7 1 23 661 684 661 684 0.97
11 26 0.0011 0.079 13.6 0.2 2 23 716 737 715 737 0.97
12 26 1.9e-05 0.0014 19.1 5.5 1 23 745 767 745 767 0.99
13 26 0.015 1.1 10.0 0.3 1 23 915 938 915 938 0.95
14 26 0.0055 0.39 11.4 0.4 2 22 946 966 946 966 0.96
15 26 0.25 18 6.2 0.7 1 23 975 998 975 998 0.90
16 26 1.1e-05 0.00081 19.8 1.9 1 23 1023 1045 1023 1045 0.97
17 26 0.00014 0.01 16.4 0.9 1 23 1052 1074 1052 1074 0.98
18 26 0.019 1.4 9.7 0.0 2 21 1101 1120 1100 1121 0.94
19 26 0.15 11 6.9 5.0 1 23 1166 1189 1166 1189 0.96
20 26 0.0026 0.19 12.4 0.8 1 23 1226 1249 1226 1249 0.96
21 26 0.015 1.1 10.0 3.1 1 23 1274 1297 1274 1297 0.97
22 26 1.4e-05 0.001 19.5 0.1 2 23 1325 1346 1324 1346 0.95
23 26 0.00017 0.012 16.2 2.9 1 23 1352 1374 1352 1374 0.99
24 26 2.4e-06 0.00017 22.0 2.0 1 23 1380 1402 1380 1402 0.97
25 26 6.1e-08 4.3e-06 27.0 2.4 1 23 1408 1430 1408 1430 0.99
26 26 0.00018 0.013 16.0 0.5 1 23 1436 1458 1436 1458 0.97

Sequence Information

Coding Sequence
ATGTTGCCGGCGGATATTTGCCGCACGTGCACGCTGCACGATGACAGCTTGCTGCCGCTGGCGACGCGCACTGATAAATATGCGAACAAAAGCTTAAGCGATATGTTGCACGAATTGACACAAAATGATCCGCTGCAGGAGCATACGGATGATAGCCTGCCGCAGCACTTGTGTATCGGCTGCATGCACAAGCTGGAGTCTGCCTATGCGTTTGTAGTGCAGGCGCGACAGGCTCAGgagcaattgctgctgcagctgcgcaaAGGCTTGCAGCCGCAGTGCCTGGAGGAGATGCCCATAGACATTAACATACAGCACATCAAAACTGAAACGGTTGTTGACTTGGATGTGCAGCTAAGAAGCAAAACCAAGAGTGAAGAGGATGAGGTGGATGCTAAAGAGGATCAAGAGATTGCAGCAGTTCCAGCACTGAAATGGCAGCCAGAAAGCGATAGTGAGAGCAATCAGGCTGCTGTTGATGGCCAGCACGTTAATGTCAAGCCCAAGCAACTGCGGCGCAGCGCACGCAAAGCCAAAGCCGGCACAGACAGTGACAACGAAATCTCATCCGCTTATGCGAATACCTTGCCTATCAAGCGTCGACGTGGTCGCCCCGCGCGTCTGCCTAAAAAGGAATCCATCGACGAGGAGGGCCGGCATGCGTGCGAGGTGTGCGGCAAGACCTTTTCGTGGTACCGCGATATGCAACGCCATTCGCGAATACACTTTGAGCAGGCAGCCTACGTATGCGACAGTTGCGGCAAGAGTTTTCTGCGCAAGGACAAGTACATGTTCCATCTGCGCTCGCACGAAAGGCGGGCAGCTAAGAGGCAAGCCCTGCAGCTGAGCAACGAATGGCGCTTTGCGGAACGCCTCTACAGCTCCGGCCGACTCAAACGTGTGGAGTGCAAGCTGTGCGGATTGAAATGTCAGCGCATAGAGGAGCTACGGGACCATCTGGCCTGCCACGACACCATGGACACGTTGTCCAAACTCAGCCTGGAGAGTGATGTTATCAGAGAGCAGTTTCCTAGCGGACAGCAGCAATTGGACTTGGAGCAGATCAAGCAACAGGTGTGTGCAGACATTGCCGAAGGACGTTGCCAGCGTGACAAATATTGCGCTGTGGTCAATGCGTATGGCTATGAGCTATGCCTGAGCGATTCGGACGAAGAGATAGTTGGCTTGGCGCCGCAATACCAGTGCCTGCCCTGCAACACCACATTTACGCGCAAATATCGTCTCATGCGACACACCCTGGAGGAGCACACACAGGCAGAAAGAGATGTGTCTTGGCAACGCTGTGATGTCTGTAAAATTGGTTTCGTGTGCCCCAAGCTACTCGAGCAGCATCAACGGACGCAGTGCCACAGCAAACTGAAGCGATACAGCTGCCCCAACTGCCCGGGCAAATTCATTTGGCTGCAGAATCTGGAACAACATGCGTGCTCGCAACGCAGCAAGCTGCAAGTGGAGCAAAAGCAGCGAAGGCAGTGTTGTCTCTGCGATGCTCAGCTAAACAGCATGCTAGAATTACGCGCTCATTTGCTCACCCATCAAGATGGACGAAGTGGAATAGATCCGGAGCAGCAGGCGACCTTCTTTCGCACCTACTATCCCAATGGCCTTGAGTGCAGCTTCTCCGAGCTGAGTGCAAGCATCGCTGCCGACTTTCAGGCGGAGAATTATGGGCGATACTTTAATGCCAGCACAGTCAGCGGCCTGGAGCTGGATTTCTTTGCCTCAGACTCTGATTTGAGTGATGCGGATGAGCTGAACTCTGGCGTGGCACTGCACATATGTTCCCTCTGTGGCGAGACGACCATACATCTAACCCAACTGCTGGAGCATCAGCTTAGCCAGCATAGTGAGCTGCAGGAGAGGCTACCACATGCCTGCGAAGATTGCGACTTGAGTTTTGTAGCCGATTCGCTTCTCCAACAGCATCGCCGACGAATCTGTGCGAAACAGCATGCCAAGTACCCTTGCCAACACTGTAACCAGCGATTTTACTGGCATTCAAATTACGAGCGCCATATGCAGGTGCAACATGCGACGCAGGCCGACGAGGAAACGGAGATTGTCGATGAGGTTCTGCAGGAATCCAGACTGAGAAGCAAACGACAGGCAACAGCTGCCAAGTTGCAATGTGGCGAGTGCGAAAAGGTCTTCATCTGGCCCAAGGATCTGACGCGGCACAAGCGCCTGCATCAGCCACAGGCGTTGGCTCAATACGAGTGCACGCATTGTGAGCGTAAGTTCCATCGTAAGGATGGACTTAAATCTCATATGCGCGTGCATAGCGAACAGCAGGTGGATGCAACGGTTGCCAGTGACCAAGTTTCATCCATGTTGCAGCGCATGCCGATGGTGCTAAGCCAACTGTGTCGACCCAATGGCTGCAAGCAGATTCAGTGCATGATATGCCTCTCGTTACACACCAAGATCTCTGATCTGCGCATGCATTTGAGCAACCATCAGTATGTGGTAAAATTTGCAGAGGAGCGTGGCCAACCGGAGAGCATTGCAAACATATCACGTGCTTTATACCCAGAGCAAGCCACGccgctggagcagcagcagctaatcGAACGCATTCAAAGGGATGTGGCCAAAGGCGAGGAGCTAGATAGATTCACATCCATTACCAACGAAGCGGGCATTGAGCTTAGCCTGGACAGCAGCGAAACGGAAACTGATTCGGACTCTGCCGAAGCAGTTGGAAGCGTCAGCGGGCAGCTCTACAGCTGTGAACTATGCCAGCTGCAGGTGCCGCGCAAGTATCAACTCTACGCCCATCAGCTGGAGCAGCATACGTGGGAGCAGGCGACGCGCGTTTGCAGCTATTGTCAGGCGAGATTCGTGaatgagcagctgctggagcaTCATTATCGCACGCTCTGCCGCAATGCGCAGCGGCGTTTCTTTTGTCGCAAATGTCCATTGCGCTTTCGATGGCGCGAGAATTTGAAGCTGCACTCGGACGTGGCTCACCAGGAAGCCAGCGGAGAGCAGTCGAAATTGAGCATTCAATTGAACGGAACGCGCCTGTTGCCCATCGTTAGCTACGACTGCACGGAATGCAATCGAAGCTTCAAAATGCAAAAGGATCTCACCAGGCACACCCTGATGCATGCCCAGGAGTCTAGCATTTACCGTTGTCGCTGGTGTGCACGACGCTTCTATCGCCAGGCCAATCTACTGCAGCACATTGAGCGTCACGGCATCAGCGCCGAACAGCTGCCCTATGCGGAGGCGCTGCTCAATGCCAGCCGTCATTCGAATGGCAAGAAATGTATCCAGTGCAAGGTGTGTAACGTGACTTACCCCACCATTGCTGCACTGCGCGCTCATCTGCAGTCAGCCCCAGCGACTACGCATCATGAGCTTGGCTCGATGCTCAACTACTCCATTACCAACCAGCTGGGATACGAGTTGCAGTTGGACGATTCGGAAACGGATGAGGAGACGAAGCCGCCTGGCACTCCCACGCACTACACCTGTGGCATGTGCCAGCTGCGCTGTGTGCGCAAGTTTAAGCTGCATCAGCACCAGCAAGCGATGCATCGACTGGAGCGCATAAGCGAAGGCTGTGATCTCTGCATCTTTAAGAGCGTATCACCAGATCTCATCGCCTATCATCGGCGCGTGCTGTGCGATAATACGGAGAAACACTTCAAATGCACCAAGTGTGGCTACAAGTTTATGTGGGAGGCGAATTTGCTGCAGCatatgcagctgcagcatccgAGCAGCGAGACGCAGCGGGAGCCCAGCTCCCTGCCCGTACCGGAAGTACCCAGTGCCGAGTGCCAGATATTTCAGTGTGGCCAGTGTCCTAGTAAATATAATCGCAAGGATCGCCTCACTGCGCACGTAAAGAAATGTCATATAGCGGGAGCAACTGGCTCCACACCTGCCTCAGCGAAGGCAGCGAAGAATTCAGCTGCCACCAAGCagcaaaaaagttttctttgtgCCTTCTGCGGCAAGGCTGTGAGCTCGTCCTCCAATCTCATCATACACATCCGTCGTCATACAGGCGAGAAACCCTTTAAGTGTGACTACTGTGAGATGGCCTTTCCGCGCTCCTCCGATCTGCAGTGCCACAGACGCACTCACACAGGCGAGCGACCGCACGTCTGCACCGTTTGTCAGAAGGGTTTCGCCCGCTCCTACAAGCTACAGCAGCACATGCGAATTCACAATGGCGAGCGTCCCTACAAGTGCACCTACTGTGACAAGAGCTTCACTCAGTCCAATGATTTGACACTTCATATACGACGGCACACGGGCGAGCGTCCCTATCAGTGCAACACATGTGGCGAGCGTTTCATTCAGGGCACAGCCTTGAAGAACCATCGGCTGCAGCATGGACACTACGAGACGGAAGTGGACCACGTCAAAAATAACTAG
Protein Sequence
MLPADICRTCTLHDDSLLPLATRTDKYANKSLSDMLHELTQNDPLQEHTDDSLPQHLCIGCMHKLESAYAFVVQARQAQEQLLLQLRKGLQPQCLEEMPIDINIQHIKTETVVDLDVQLRSKTKSEEDEVDAKEDQEIAAVPALKWQPESDSESNQAAVDGQHVNVKPKQLRRSARKAKAGTDSDNEISSAYANTLPIKRRRGRPARLPKKESIDEEGRHACEVCGKTFSWYRDMQRHSRIHFEQAAYVCDSCGKSFLRKDKYMFHLRSHERRAAKRQALQLSNEWRFAERLYSSGRLKRVECKLCGLKCQRIEELRDHLACHDTMDTLSKLSLESDVIREQFPSGQQQLDLEQIKQQVCADIAEGRCQRDKYCAVVNAYGYELCLSDSDEEIVGLAPQYQCLPCNTTFTRKYRLMRHTLEEHTQAERDVSWQRCDVCKIGFVCPKLLEQHQRTQCHSKLKRYSCPNCPGKFIWLQNLEQHACSQRSKLQVEQKQRRQCCLCDAQLNSMLELRAHLLTHQDGRSGIDPEQQATFFRTYYPNGLECSFSELSASIAADFQAENYGRYFNASTVSGLELDFFASDSDLSDADELNSGVALHICSLCGETTIHLTQLLEHQLSQHSELQERLPHACEDCDLSFVADSLLQQHRRRICAKQHAKYPCQHCNQRFYWHSNYERHMQVQHATQADEETEIVDEVLQESRLRSKRQATAAKLQCGECEKVFIWPKDLTRHKRLHQPQALAQYECTHCERKFHRKDGLKSHMRVHSEQQVDATVASDQVSSMLQRMPMVLSQLCRPNGCKQIQCMICLSLHTKISDLRMHLSNHQYVVKFAEERGQPESIANISRALYPEQATPLEQQQLIERIQRDVAKGEELDRFTSITNEAGIELSLDSSETETDSDSAEAVGSVSGQLYSCELCQLQVPRKYQLYAHQLEQHTWEQATRVCSYCQARFVNEQLLEHHYRTLCRNAQRRFFCRKCPLRFRWRENLKLHSDVAHQEASGEQSKLSIQLNGTRLLPIVSYDCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNASRHSNGKKCIQCKVCNVTYPTIAALRAHLQSAPATTHHELGSMLNYSITNQLGYELQLDDSETDEETKPPGTPTHYTCGMCQLRCVRKFKLHQHQQAMHRLERISEGCDLCIFKSVSPDLIAYHRRVLCDNTEKHFKCTKCGYKFMWEANLLQHMQLQHPSSETQREPSSLPVPEVPSAECQIFQCGQCPSKYNRKDRLTAHVKKCHIAGATGSTPASAKAAKNSAATKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCEMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQHGHYETEVDHVKNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00509945;
90% Identity
-
80% Identity
-