Dfuy002566.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila fuyamai
Gene Symbol
-
Assembly
GCA_018153365.1
Location
JAECXW010000062.1:3437587-3441691[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 9.7 7.5e+02 0.9 0.7 2 23 144 166 143 166 0.90
2 13 0.0018 0.14 12.7 5.0 1 23 187 210 187 210 0.97
3 13 3.4e-06 0.00027 21.2 5.5 2 23 217 239 216 239 0.96
4 13 0.0091 0.7 10.5 9.0 2 23 454 475 454 475 0.97
5 13 1.6e-06 0.00013 22.3 2.9 1 23 481 504 481 504 0.95
6 13 0.00069 0.054 14.0 0.8 1 23 509 532 509 532 0.93
7 13 1e-05 0.00079 19.8 4.7 1 23 550 572 550 572 0.97
8 13 7.1e-05 0.0055 17.1 0.7 1 23 577 599 577 599 0.98
9 13 2.8e-05 0.0022 18.4 1.7 1 23 605 627 605 627 0.95
10 13 2e-05 0.0016 18.8 0.7 1 23 633 655 633 655 0.98
11 13 2.9e-07 2.3e-05 24.6 2.7 3 23 663 683 662 683 0.99
12 13 2.1e-08 1.7e-06 28.2 1.1 1 23 689 711 689 711 0.99
13 13 0.33 25 5.6 3.4 1 19 716 734 716 739 0.89

Sequence Information

Coding Sequence
ATGGCAACGGAGCAGCCACACCCGCACCTGCAGTTGGAGCTGGGTTCGGGTCAGGAGTCGGAAAGTCAGCCGGCGGGGAGCAAATTTGTGGCCCAGCACACCATGGACGCGGAGCGCGTCTGTCGCGTTTGCCTGAAGGATGCATCGCTGGGCGGGGAGCTGCACTTCATCTTCGAGGAGGCGCCCGTCGAGGAGGACGCCAATCTGGCCCGCATCCTGGACGAATGCACGCTGCACCAGTGCCAGCGGCACGACGGGATGCCCCCGCACATGTGTGGCTCTTGCGTGGAGGCGGCACGCCATGCCTATCGCTTTAAGCGGCACGCAGAGCGTTCATACTGCTCGTTGGTGGCCCTACTGGGCCGGTCGCCCCAGCTGAAGGCCCGCGGTGCCGAGGCGGGCAGTCAGACGGATCAGGTGGCGTTGCTGCCCTGCGAAATGTGCCACGACCAGTTCCTTAACAGCCTGGAGTTGCGCCTTCACCGCAACCAGGTTCACAGGACGACCAAGGAGGGCGCTGCCACTGGCACAACCACGGAGGCCAATCAGGTCGAGGAATTCAAGTGCAAGTTTTGCCCCCAGCATTTTCCGCATCTGCGACAGCTGCGCAGCCATTTGGCGCGGAGCCACGAGCAGACCGCTCGACTTCAGTGCGCCCATTGCCAGCGCACCTTTAGCCGCCGGGATCATTTGCTGCGCCACATGCGAAACCAACACCGGGGCCTGGAGGAGGACCTCCTGCGCACCTGGCCGGCGGCGGATGAAAACACCATGCAGAGCGATGGCGGGGATGAGCTGGTCTCGGCCGAGGTGCTGCTGAACGAGGAGTGCAATACGAATCCCATTTCCAGCAACGAGGAAGAGGACGAAGACGCCAATGGGGCCAATCAAACGCTGTGGCTGCACATCAAGCCAGAACCCTGCCTTGAGGCGGAGGAAGTTGATCTGGCCATGCAGCTGAAGCTCGACAAAAAGCGTCGGCGGCGGGAGAAGGCGGAACCTCAAGCCGAGAGCTCCATTGATGGGACTGTAAAGAATGAGCCCATTGCCATAAGCATTAAGGAGGAGAGCCACCTTGTGGGCAGTGAGGACGAGGCACCAATGGGAGTTGAAGATTTCATGAAGCTACATGTCAGCGGAGAACTGCCGCTTAGCGATGATGAGGATCATTTCGAGGAGTTCATCGACGAAGACAGTGACCTGGATGAGGACGAGGAGGACGACGAGGACGGAGGGGAAGACGACGATGGGGAATTCCGGCTTAAGGAGGAGCCGCTGGACGGCCAGAAGCAGCCGAAGAGGTCCAAGTCCGGCAGGCGTCGGCGACGAAACAAGCAGAGCGAGCCTAATCCTGAAAACCGTTGTGAAGTGTGCCAGCGCACCTTCTCGCGTCACTGCCACCTGCTGCGCCACAAGCTGTCGCACCTGGAGAAGAAGCCCCACAACTGCCCACACTGTCCCAAGGCTTTCGCGCGCAGCGACCATCTCAAGGCGCATGTGCAGAGCCTGCACAGCAACAAGGAGCACAAGTGCGGACTTTGCGAGGCCGCCTTTTCGCGGCTGGACTCCTTGGAGCGTCACAAGGTCAGCAAGCATAATGGCGAGGGTCTGGAACCGGGCAGCGAGCTGAAGCTGCAGCTGGCGGAGCATACCTGCGAGTACTGCTCCAAGCGCTTCTCCAGCAAGACCTACCTGCGCAAGCACATCCTGCTGCACACCGACTTCCTGTACGCCTGCAAGACCTGCGAGGAGACATTCCGCGAGCGAGCGCAGCTTAGGGAGCACGAAAAGACCCACACCGGACAGCGGAACTTCCTCTGCTGCATCTGCGGCGACAGCTTTGCCCGCAACGACTACCTGCGTGTGCACATGCGACGCCACAACGGCGAGAAGCCCTACAAGTGCCGCTACTGTGTTAAGGCTTTCCCCCGCGCCACCGATCTCAAGGTCCACGAGCGGTACCATACGGGAACCAAGCCGAACCTGTGCAATACCTGCGGCAAGAGCTTCCACCGGGCTTACAACCTGACCATTCACATGCGGACGCACACCGGCGAACGGCCGTACAAGTGCGACCAGTGCCCCAAGAGCTTCACCCAGAGCAACGACCTCAAGGCGCACATCCGGCGGCATACGGGCGAGCGGTACAAGTGTCCGCACTGCGACGCCTACTTCCTGCAGCTGTACAACATGCGGAACCACTGTTTGAGCGCCCACAACAAGCACATCGAGACGAAGACGGGGCGTCTTCAGCGGACGGGCCTGCTGGACGATGGCGGCCAGTCGCATTTGACCACGGTGGTCATGCCGCCAGCGCGATACCAACCTGGAGTGGATCCCCTGATGGCGGCGGCGGCTGCTGTCGGGGCTGAAAGCTCATCATCGACCACCGTCATCCATTCACCAGGGACGTACAATGCCACATCCTCCGGACTGGCTCCGGAGTCGGCGTCCGCTGCTCCAGCCAGCACTCTGGATGGAGCCAGCTTTGCACCAACGGCGGTGAATGCGGCGGCTCCTTTTGGCGCCTTCAACTTTCCGCCGGCTGTTATGGCGCATCTCATGTACAACCATGGAGGAAGCAGTCAGCACAGCCAGAGCGGCAGCGATACGGGCAAATAG
Protein Sequence
MATEQPHPHLQLELGSGQESESQPAGSKFVAQHTMDAERVCRVCLKDASLGGELHFIFEEAPVEEDANLARILDECTLHQCQRHDGMPPHMCGSCVEAARHAYRFKRHAERSYCSLVALLGRSPQLKARGAEAGSQTDQVALLPCEMCHDQFLNSLELRLHRNQVHRTTKEGAATGTTTEANQVEEFKCKFCPQHFPHLRQLRSHLARSHEQTARLQCAHCQRTFSRRDHLLRHMRNQHRGLEEDLLRTWPAADENTMQSDGGDELVSAEVLLNEECNTNPISSNEEEDEDANGANQTLWLHIKPEPCLEAEEVDLAMQLKLDKKRRRREKAEPQAESSIDGTVKNEPIAISIKEESHLVGSEDEAPMGVEDFMKLHVSGELPLSDDEDHFEEFIDEDSDLDEDEEDDEDGGEDDDGEFRLKEEPLDGQKQPKRSKSGRRRRRNKQSEPNPENRCEVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCGLCEAAFSRLDSLERHKVSKHNGEGLEPGSELKLQLAEHTCEYCSKRFSSKTYLRKHILLHTDFLYACKTCEETFRERAQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLDDGGQSHLTTVVMPPARYQPGVDPLMAAAAAVGAESSSSTTVIHSPGTYNATSSGLAPESASAAPASTLDGASFAPTAVNAAAPFGAFNFPPAVMAHLMYNHGGSSQHSQSGSDTGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00504826;
90% Identity
iTF_00529698;
80% Identity
-