Basic Information

Insect: Drosophila fungiperda
Gene Symbol: wek
Assembly: GCA_035042345.1
Location: JAWNLM010000165.1:2633311-2635202[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00011 0.0077 16.6 0.7 1 23 248 271 248 271 0.97

2 8 0.0049 0.34 11.4 1.5 2 23 282 303 281 303 0.97

3 8 1.9e-05 0.0013 19.0 1.1 2 21 313 332 313 335 0.94

4 8 0.78 54 4.5 0.5 1 23 341 363 341 363 0.95

5 8 0.0002 0.013 15.8 3.5 1 23 369 391 369 391 0.97

6 8 8.5e-05 0.0059 16.9 0.4 1 23 396 418 396 418 0.98

7 8 2.4e-05 0.0017 18.7 0.1 1 23 424 446 424 446 0.97

8 8 0.0071 0.49 10.9 5.4 1 23 452 475 452 475 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00011	0.0077	16.6	0.7	1	23	248	271	248	271	0.97
2	8	0.0049	0.34	11.4	1.5	2	23	282	303	281	303	0.97
3	8	1.9e-05	0.0013	19.0	1.1	2	21	313	332	313	335	0.94
4	8	0.78	54	4.5	0.5	1	23	341	363	341	363	0.95
5	8	0.0002	0.013	15.8	3.5	1	23	369	391	369	391	0.97
6	8	8.5e-05	0.0059	16.9	0.4	1	23	396	418	396	418	0.98
7	8	2.4e-05	0.0017	18.7	0.1	1	23	424	446	424	446	0.97
8	8	0.0071	0.49	10.9	5.4	1	23	452	475	452	475	0.98

Sequence Information

Coding Sequence: atgacgGGCAGCGAGGCAGTTGCAAGTGCTGGAAAAGGGATAGGCTCTACGCAGAGCAGAGAAACAACTGTTTGGCACCAGTGGTGCCGCCTGTGCGCCAAAGAGCATCCGGATAACTTAAATGTGTATTTCCGAGATGGCAATCAGACATGGACGAGCGTTCTGGCCGTGGCTATTGGTAAATACTTTTGGGTTAATATTAAAATGGAGGACGAGCTCAGCAATGTGCTGTGTAAGGAGTGCTATACTCTGGTTGAAGATCTCATCGAGTTTTCGGAACGAGTCAATCGAGTTCAAACGCTTTTCAGCCGACTACAGCAGGTTGGCAATAAGGCCACCTTAGACTATAATGAATTGAGAAAGGATTGCGGATTGCAAGCGGATGAGTGGAAGCACTTTGCCGCGAAGGATGCAACGCATGCTGATAAAACAGATGCAAATACAGTCGATTATATTATGGAGTCGATCGATGAAGATGCTGAAACTGAACTAATGACTGATATCGAAGAGAATCCGTTGGAGGATAATGAAGAGAACACATACGAGTCATATGTGGACCAGGAAGACGAAGAGCAGGTAACACAAGAgacggcagcagcaccatACGTTGAACAAGATGAATACACAAACCAGGAGGAGGAGCAAGAAATACCCAAGTCAACAATGACAACGGACGAGGATGTTGAAAAGATCACAGAGGCTCATCTAGCGGAAAATGAGGACGATTCAATGGATGGCCCATACAAGTGCACATCGTGCAATCGTAGCTACAAACTGCCCATGGCTTTTAAGCGGCATATGGCTGTCGTCCATGGCTTAGCTGCCACAGATAAAGATAAATTGGAATGCAAACGCTGCCACATGTTGTTTGCAACCGAAATTCAGTTGACTGCCCACTTTCGCAGCCACTTGCCGTCCAAGGACAAAACGGAGAATACTTGCACCTACTGCCCGAAACAGTTCACCACAGCTGGAGCGCTGAAGCGGCACATAATGTGCATCCATGAGAATGTGAAGCCGTACATATGCGACTGCTGTGGCAAAGGCATGAAGACCATTACGGCCCTCAACGAGCACAAACTGGTGCACACGGATGAGTGTCCCTTCGAGTGCACCGTTTGCCATCGTCGCTTCAAGAACAAGGCCAGGCTAAAGATACACTCGGATACTCACACGAATGACAGCTACGAGTGTAATATATGTGGCTTGAAGCTGAATACACGTCGTACTCTCAACATGCACCAATTGGTGCACACGGATGCCAAGCAGTACAAGTGTGATGTGTGTGGCGCCGCCTTTAAGCGTGGCAAAACGTTGAAGGCACATCTGATCCTACATACCGGCATACGTCcgtataaatgcaatttttgtggACGCGACTTTTCGAATGGCTCCAATTGTCGCATGCACAAGCGCAAGACACATCCCAAAGAGCTGGCGGAGGAGGAGGCGCGTGGCGTTATGCGTTCTACACTGCTGCCCATGATCACAGAACTGACTGAAGCTTCGAAACGTGTGAAAAAACCAGCTAAACCAGGCACATCGTTAATGCATGTTAGGGTAACTGAGGAGATCACAGATCACAATTCAACAGCTGCCAAGATGTCCGAAGATGAGCtcgacgaggaggaggaggaggaggacgaaGCGGATAATGCAGTGCTTTACGAGATCGTAGAGGagtgcacataa
Protein Sequence: MTGSEAVASAGKGIGSTQSRETTVWHQWCRLCAKEHPDNLNVYFRDGNQTWTSVLAVAIGKYFWVNIKMEDELSNVLCKECYTLVEDLIEFSERVNRVQTLFSRLQQVGNKATLDYNELRKDCGLQADEWKHFAAKDATHADKTDANTVDYIMESIDEDAETELMTDIEENPLEDNEENTYESYVDQEDEEQVTQETAAAPYVEQDEYTNQEEEQEIPKSTMTTDEDVEKITEAHLAENEDDSMDGPYKCTSCNRSYKLPMAFKRHMAVVHGLAATDKDKLECKRCHMLFATEIQLTAHFRSHLPSKDKTENTCTYCPKQFTTAGALKRHIMCIHENVKPYICDCCGKGMKTITALNEHKLVHTDECPFECTVCHRRFKNKARLKIHSDTHTNDSYECNICGLKLNTRRTLNMHQLVHTDAKQYKCDVCGAAFKRGKTLKAHLILHTGIRPYKCNFCGRDFSNGSNCRMHKRKTHPKELAEEEARGVMRSTLLPMITELTEASKRVKKPAKPGTSLMHVRVTEEITDHNSTAAKMSEDELDEEEEEEDEADNAVLYEIVEECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00518682;
90% Identity: iTF_00500557;
80% Identity: -