Basic Information

Insect: Drosophila fungiperda
Gene Symbol: PRDM1
Assembly: GCA_035042345.1
Location: JAWNLM010000028.1:4315639-4320208[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2.9e-05 0.002 18.4 2.5 1 23 929 951 929 951 0.99

2 5 8.8e-06 0.0006 20.0 5.1 1 23 957 979 957 979 0.98

3 5 1.8e-06 0.00013 22.2 4.3 1 23 985 1007 985 1007 0.98

4 5 0.00061 0.042 14.2 2.4 1 23 1013 1035 1013 1035 0.97

5 5 0.0001 0.0071 16.7 0.1 1 22 1041 1062 1041 1062 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2.9e-05	0.002	18.4	2.5	1	23	929	951	929	951	0.99
2	5	8.8e-06	0.0006	20.0	5.1	1	23	957	979	957	979	0.98
3	5	1.8e-06	0.00013	22.2	4.3	1	23	985	1007	985	1007	0.98
4	5	0.00061	0.042	14.2	2.4	1	23	1013	1035	1013	1035	0.97
5	5	0.0001	0.0071	16.7	0.1	1	22	1041	1062	1041	1062	0.96

Sequence Information

Coding Sequence: ATGCAtggacatcatcatcatcatcatcagcagcagcagcatcagcagcaacagcagcagcaaccgttgcagccgcagcaacaagtgcaacaaatgccAGTCGCaatgaagcagcagcagctgcagcaacagcaacaacaaacacaacacatagccatacagcaacaacaccagcagcagcagcagcaaacgcatccgcatcatcatcatcatgcaGCAGCACAGCATCCGCAACGGCATTCACAACAGCATCCACAACAGCATCCACATGCGCATCCACATCATCACGCAAAGCTGCTGCGTCGCTcgcgcagtcgcagtcgcagtccgACGCCGGATGGTACACAGGACTACGATGTGACGCGCATGCGCGAAGAGGACTTTGAGCGTCTAGCGGTATATCTGGTGCCCGATGTGCAAGCAGAGCGAGGCTTGCCCAATCGTGCCGATAAAACGCTGCCGCGCAGCCTAACGCTCAAATCCTCAATGGTCTACTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGCGGCGTTATACCGCGTGGCACTCGCTTTGGCCCATTCGAAGGCATTCCAACCTCAAATTATCCAAATGATAAGAATAAGGCGCGATATTTCTGGCGGGTGCAGGGAACACGCCACATAACCTACGGGATTATTAAGATCTTCAAGGATGATGATTATTACTATCTGGATGGCTCGGATCGCTCGGAATCCAATTGGATGCGTTATGTTGCCTCGGCGTATAGCTTGTCCGTTATGAATCTAGTGGCTTGCCAGCACCAGGATAACATCTATTTCTATACCACCCGCGACATATTGCCCAACGAGGAGCTGATGGTCTGGTACTGCAAGGACTTTGCCAGCCGCCTGGGATACGATGTGGACCCGGAGCGCACTATTTTCGGTGCCTGCAAAcaggatgtggatgtggatgaggatgaggacgaTGAACTGCCGCACAAGAAACCCCACTATGCAATGCCCGCTCCCGAAATACCCGCCGAGGTGGCTGTCAGTCACATTACCTATGTAATGGGATTGCATTTGCCCGGTGcaccacctccaccaccaccacccgcAGGATCAGTTTCATCGGCAGCGCCAGCACAATCATCCGCCCAATGCTGCCGTCGTGGCAGTCCACCTGCCCATGTCAGCACcacaaccagcagcaacaccagctcCAATTCCCTACATCCGCATATACAGCACAGTCGTCATGCTTCGGTTATCATTGGCCAGGATCGGTCTCCCCTAAACAGTAGCTGTGAGAAGGAGACGGCTGGTTCACCGCTCTGTGGCAAGGATGCCCACTATGAGCATCAGTTGACGCCGCAGGATGGCAGCGTGCGATCGGTGCGATCCGATGAGGGTTACCACAGCAACGAGTGCCAGGAGGATGGACTAACGCCACCCGAGGATTCCAGTGATAGCGAAAGTGAGCATAACTATGTGCTCGACTGCTCCAAGAAGGCAATTGCACCCAAGGAGACGGTCATTGCGCAGGCGCAAAAGCCGAGCAGTGTCTCTTCACCACCAGCAGTAACCAACAATGGCAATaacaccaccagcaacagcaccaccaTCAGCAGCGCCACCATCATGCCCACCGCTGCCGTTGTCACGCCCAGTTGTGAGGCGGATAAGAACGAGTATCGTAAGTTCAAGGTGAAAATGCCACTAAAATATGAGTTCAAGAACAAGAGCTGTGTGAAAACGGAACCACTTAAGGAAGTGGATGAGCAACTGCCGCCAGTTGGTGTCGGtctggaggaggaggatgtaCATGAACTGCATGGTGTAGCGACGACGCATTGCGAGGATTCATTGTGCCCGCCCAGCACGACAACAACGCTCGGTGAGGAGCACCATCAGCTGCAGCATGTGGTGGAGCCAACTAATCCACAGCCAGCCTCCTCCACGGTGATTGTGCTGGAGCACAGCTCCAATGGACAGACGCGAACCATTGTGCCGCTGAGTAAGCCCTACTACGAGGCCGATCCGCCCGTGGATCGCTATGTGCGCTTCACACAGCCCAGCTCAAGCATCCTGGAGACGATACTCACCAGCCAGCATCGCTTGGAggcagctgccgccgctgcaaATGCCTGTAGGCAGGCCAATGCTGCAACACCACCGCCCACATCGCCCACAGAGATGGCCTACAGCTATAAGAAATCGCAGCGCTATGGCAATGCAGTGAGTCCCGATTCCAGCTCCAATCTGGGACAGCCGCAGGAGCTCAGTGGTGCGCATGTGGTGCAGGAGCAGGAGATGGGTCTGAGTCGTGGTGCACTGATCAAAGGCGAATGCTCTCCACCGCCTCCATCCTCGCATCATCATCACAATGTGATCTATTCGCCGACGAGGACGCATCACGGTGGCTACGAACCGGGCAGCCATTCGCCCAGCTATGCCGGCTATGCGGGCTATCCCGGATCACAATCCCTGCATGCGGCAACTTCGACGTTCCACTCACCGCCCCACAGTTCGCACTCCCCCTTCGATCGCCAGTCGAATGCGTCGAGTGGCGGTGGATCCGCTTCCAACTTGCATCTGCTGCAAAGCAGCACACAAATGTTGAATCATCCGTTGATGCAACCGTTGACGCCGTTGCAGCGTCTCTCTCCGCTGCGCATCTCCCCACCCAGCAGTCTGAGTCCCGATGGCAACTCCTGTCCACGCAGCGGCAGTCCCCTCAGTCCCAACTCGTTGGCCTCGCGCGGCTATCGCTCGCTGCCGTATCCCCTGAAAAAGAAGGATGGCAAAATGCATTACGAGTGCAATGTGTGCTGCAAGACATTTGGCCAGCTGAGCAATCTCAAGGTGCATCTGCGCACCCATTCCGGTGAGCGTCCGTTCAAGTGCAATGTGTGCACGAAGAGCTTCACACAGCTGGCGCATCTGCAGAAGCATCATCTGGTGCACACGGGCGAGAAGCCGCATCAGTGCGATATCTGCAAGAAGCGCTTCTCCAGCACATCCAATCTGAAGACCCATCTCCGGCTGCACAGCGGCCAGAAGCCCTACGCCTGCGATCTCTGCCCCCAGAAATTCACAcaatttgtgcatttgaaGCTGCACAAGCGTCTGCACACGAATGATCGGCCTTATGTGTGCCAGGGTTGCGATAAGAAGTATATCAGTGCGTCTGGACTGCGCACACATTGGAAGACGACCAGCTGCAAGCCCAACAATCTGGAGGAGGAACTGGccatggcagcagcagcgacttcCGAGTGTTTGGACAAAGATCTACCGGAGCCGGATTCGCGTGAGGCATATGAGCAGCTGCACCAGCACATGCATCCAGTGCATCCCAGCTTGCGTCATTTAGCTGGCACCCAATCACCGCCGCGTCTCATTCCGCTGGGCAGCAATGGACAGCCGCATATGCATATGCGACAGCATTCACATCCGACGCCGCCGGGACATATAATGCACTCACCACATGGTGGTCCGCCCATGCTGTTGACCACAGCCAATCAGTTACCGCCACCAGCAACGCCACAtcacatgcagcagcagcagcaacagcagcagcagcagcagcaacaacaaccttTGCCACAAGTCTCACCAGgcagacagcaacagcaatcacaGCATTTGGGTGCAGCACATCATTTGGCGCAGCATTCGCCCAAGTCGCTGAAACCTTTGCCGGATAACGGCTATCTGCATGGGCCGCATGTGCAGGCGCAGGAGAATCGACCCTCGGTCATTGAGTCCTCCAGCCAGCCCATGATCATTGAATGCACGTAG
Protein Sequence: MHGHHHHHHQQQQHQQQQQQQPLQPQQQVQQMPVAMKQQQLQQQQQQTQHIAIQQQHQQQQQQTHPHHHHHAAAQHPQRHSQQHPQQHPHAHPHHHAKLLRRSRSRSRSPTPDGTQDYDVTRMREEDFERLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGIIKIFKDDDYYYLDGSDRSESNWMRYVASAYSLSVMNLVACQHQDNIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPERTIFGACKQDVDVDEDEDDELPHKKPHYAMPAPEIPAEVAVSHITYVMGLHLPGAPPPPPPPAGSVSSAAPAQSSAQCCRRGSPPAHVSTTTSSNTSSNSLHPHIQHSRHASVIIGQDRSPLNSSCEKETAGSPLCGKDAHYEHQLTPQDGSVRSVRSDEGYHSNECQEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPSSVSSPPAVTNNGNNTTSNSTTISSATIMPTAAVVTPSCEADKNEYRKFKVKMPLKYEFKNKSCVKTEPLKEVDEQLPPVGVGLEEEDVHELHGVATTHCEDSLCPPSTTTTLGEEHHQLQHVVEPTNPQPASSTVIVLEHSSNGQTRTIVPLSKPYYEADPPVDRYVRFTQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQPQELSGAHVVQEQEMGLSRGALIKGECSPPPPSSHHHHNVIYSPTRTHHGGYEPGSHSPSYAGYAGYPGSQSLHAATSTFHSPPHSSHSPFDRQSNASSGGGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDLPEPDSREAYEQLHQHMHPVHPSLRHLAGTQSPPRLIPLGSNGQPHMHMRQHSHPTPPGHIMHSPHGGPPMLLTTANQLPPPATPHHMQQQQQQQQQQQQQQPLPQVSPGRQQQQSQHLGAAHHLAQHSPKSLKPLPDNGYLHGPHVQAQENRPSVIESSSQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610151;
90% Identity: iTF_00498390;
80% Identity: -