Basic Information

Insect: Drosophila fungiperda
Gene Symbol: Znf296
Assembly: GCA_035042345.1
Location: JAWNLM010000145.1:10505400-10507007[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2.5e-06 0.00017 21.7 3.2 1 23 225 247 225 247 0.97

2 11 8.3e-05 0.0057 17.0 4.4 1 23 253 275 253 275 0.99

3 11 2.4e-06 0.00016 21.8 0.3 1 23 281 303 281 303 0.98

4 11 1.5e-05 0.001 19.3 5.8 1 23 309 331 309 331 0.98

5 11 3.4e-06 0.00024 21.3 0.9 1 20 337 356 337 359 0.93

6 11 8.5e-07 5.9e-05 23.2 5.4 1 23 365 387 365 387 0.98

7 11 2.7e-06 0.00019 21.7 1.1 1 23 393 415 393 415 0.99

8 11 9.1e-07 6.3e-05 23.1 5.0 1 23 421 443 421 443 0.98

9 11 1.5e-05 0.001 19.3 0.3 1 23 449 471 449 471 0.98

10 11 1.6e-07 1.1e-05 25.5 0.4 1 23 477 499 477 499 0.96

11 11 7.2e-06 0.0005 20.3 2.0 1 23 505 527 505 527 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2.5e-06	0.00017	21.7	3.2	1	23	225	247	225	247	0.97
2	11	8.3e-05	0.0057	17.0	4.4	1	23	253	275	253	275	0.99
3	11	2.4e-06	0.00016	21.8	0.3	1	23	281	303	281	303	0.98
4	11	1.5e-05	0.001	19.3	5.8	1	23	309	331	309	331	0.98
5	11	3.4e-06	0.00024	21.3	0.9	1	20	337	356	337	359	0.93
6	11	8.5e-07	5.9e-05	23.2	5.4	1	23	365	387	365	387	0.98
7	11	2.7e-06	0.00019	21.7	1.1	1	23	393	415	393	415	0.99
8	11	9.1e-07	6.3e-05	23.1	5.0	1	23	421	443	421	443	0.98
9	11	1.5e-05	0.001	19.3	0.3	1	23	449	471	449	471	0.98
10	11	1.6e-07	1.1e-05	25.5	0.4	1	23	477	499	477	499	0.96
11	11	7.2e-06	0.0005	20.3	2.0	1	23	505	527	505	527	0.97

Sequence Information

Coding Sequence: ATGGAGCAAATTTGCCGTGCATGCAAAATCAGCTCCAACAACCTAGTGAACATATTCTCAGAGGGACAGCCAAGTCTGGCGGAGATGTTGAGCGAGTGTGTTGGCTGTGTAATCAATCAAAATGATGCATCTCCCCAGCAGCTGTGCCTATCCTGCGTCAACGCTGCACAAAATGCGTTTCGTTTGATGCGCAACTATGAACAGAaagcgccaaaaaaaaaaacttgccgCATTTGCAGAAGCACCTCAGTTACGCTAATTGAGATTAATGCCAGGCGGCAGCAGCCTCAGGGGGAACCCAGTTTAGCGGAAATGATAAAAGAGTGCATTGGCCGTCGGACAAATCCCAGGGGTCAGATATGCCTGTCCTGCATTTTGAGCGTTGAAAACGCTTTTCAATTCAAGCGCAGATGCGAGCAGAGCCAGCAGCAGattaaaactgaaattcaaGAAAGTGAAGCAGTTGAAAAAGCACTTTGCGATAACAGCTTCGAAATAGAGCAACAAGAATATAGCATTAAAATTGAAGTCAATGATAATGAAGAAGACTTTGAATACGAGCAGACTCAGATAATGTTAGAGGAGCAGAAGTGTGAAGAGAAATTGGAAGTGAATCCTTCGCCTGTCAATAATCATTTCCCAGCAGAGATTGCAGTGGATGCAAATAAGAAACACATGTGTGAGATGTGTGGCAAAAGGTTCTCGAACACTGCTCACCTGATGGTGCATAGACGAATCCATTCCGGTGAACGTCCGTTCAAGTGTTGCGAGTGTCAAAAGGATTTCACAAGTCGTAAAGTGCTCAAGGATCACATGCTCACCCACACCGGCGAACGGCCATTTCAGTGTGCCCAGTGTCCCAAGTCATTTGGAAGGAGTGGTGGTCTGGTTAAACACATGTTCACGCATACGGGCGAACGGCCCTTCAAGTGCAGCCACTGCCCGAAAGCCTTCTATCAGAAACAACATTTGAAGATCCATAATCGCATTCATACTGGGGAACAGCCATACAAGTGCCCCCATTGCCCACGAGCCTTTCCACGCAAGGAGTATCTGACGACGCACCTACCAATGCATACGGGAGAGCAGCCACACCAGTGTCCCCACTGTTCCAAGTCCTTTTCCCGCAGCAAAAACTTAGAGATGCACTTGACCACGCATACGGGTCAGCAGCCCTATCGGTGTCCCCATTGCATCAAGGTGTTCACCGCCAATTCAAATCTTCAAATCCATATCCGGAATCACACGGGCGAACGTCCTCACAAATGTCCCCACTGTGAGAAGGCGTTCAGCCAAAGCGGTTGCCTCCAGAATCACATACGCATCCACACCGGCGAACGACCGTTCCAATGTGCCCAATGCCCGAAGACTTTCGCCACTAACGGTGGACTGTACAATCACAATCGTGTCCACTCCGGCGAACGTCCCTTTCAGTGTCCACAGTGCCCGAAACGATTTCCGCGTAAGGAGAATCTGCGCAATCACATTGGTCTCCACTCCGAGGATCGGCCGCACAAGTGTAACCTGTGTCCCAAGGACTTTACCCGCCGCGAGAGTCTAGCCCGGCACAAGCTGAttcatgaaaaaaataaaaaatcaaatgattaA
Protein Sequence: MEQICRACKISSNNLVNIFSEGQPSLAEMLSECVGCVINQNDASPQQLCLSCVNAAQNAFRLMRNYEQKAPKKKTCRICRSTSVTLIEINARRQQPQGEPSLAEMIKECIGRRTNPRGQICLSCILSVENAFQFKRRCEQSQQQIKTEIQESEAVEKALCDNSFEIEQQEYSIKIEVNDNEEDFEYEQTQIMLEEQKCEEKLEVNPSPVNNHFPAEIAVDANKKHMCEMCGKRFSNTAHLMVHRRIHSGERPFKCCECQKDFTSRKVLKDHMLTHTGERPFQCAQCPKSFGRSGGLVKHMFTHTGERPFKCSHCPKAFYQKQHLKIHNRIHTGEQPYKCPHCPRAFPRKEYLTTHLPMHTGEQPHQCPHCSKSFSRSKNLEMHLTTHTGQQPYRCPHCIKVFTANSNLQIHIRNHTGERPHKCPHCEKAFSQSGCLQNHIRIHTGERPFQCAQCPKTFATNGGLYNHNRVHSGERPFQCPQCPKRFPRKENLRNHIGLHSEDRPHKCNLCPKDFTRRESLARHKLIHEKNKKSND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00499011;
90% Identity: iTF_00543881;
80% Identity: iTF_00511430;