Basic Information

Insect: Drosophila funebris
Gene Symbol: -
Assembly: GCA_018901825.1
Location: JAEIFK010000678.1:18804481-18810984[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0094 0.64 10.5 3.2 1 23 840 862 840 863 0.95

2 8 0.13 8.8 6.9 2.2 1 23 868 890 868 891 0.95

3 8 0.00014 0.0096 16.2 0.7 1 23 1151 1174 1151 1174 0.96

4 8 0.0021 0.15 12.5 0.8 2 23 1183 1204 1182 1204 0.97

5 8 0.034 2.3 8.8 0.3 1 23 1211 1234 1211 1234 0.96

6 8 5.7e-06 0.00039 20.6 1.4 1 23 1240 1262 1240 1262 0.97

7 8 9.2e-06 0.00063 20.0 1.5 1 23 1267 1289 1267 1289 0.99

8 8 0.0048 0.33 11.4 6.0 1 23 1295 1317 1295 1317 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0094	0.64	10.5	3.2	1	23	840	862	840	863	0.95
2	8	0.13	8.8	6.9	2.2	1	23	868	890	868	891	0.95
3	8	0.00014	0.0096	16.2	0.7	1	23	1151	1174	1151	1174	0.96
4	8	0.0021	0.15	12.5	0.8	2	23	1183	1204	1182	1204	0.97
5	8	0.034	2.3	8.8	0.3	1	23	1211	1234	1211	1234	0.96
6	8	5.7e-06	0.00039	20.6	1.4	1	23	1240	1262	1240	1262	0.97
7	8	9.2e-06	0.00063	20.0	1.5	1	23	1267	1289	1267	1289	0.99
8	8	0.0048	0.33	11.4	6.0	1	23	1295	1317	1295	1317	0.99

Sequence Information

Coding Sequence: ATGGTTGCAAAGTTCCGGCGGCGTTGTGTGCGCGTCCAGCAGCGTCTCCAGGCGTTCGCTGATGACATTGCCGAGCGCAAAGCAAGGCGACGCCCCGACAAGCTATACCAACAACAACAACAACAGACAAATGAGGCGGATGTGATGGAGTACATGCATCTGCCGGAATCACAATTGGAGCGCAAGCGTCGATTGAAATCTGTTGAACCGGAACTAGACGCAAAACAAGCCCAGCCTGCTGCGAAAGAGCATCCGCCATCGGCAAAAATGCGGCGCGTTCAGTTGCAACGTAGATCTCTGCCAGCCAATAATAACATTGAGACTGAAACAATGACAACGAGAAGCTTGTCACACCAGAGGAAAGTTCGAGAGAGAGTTCCGACGAGGTCACCTCAAAAAAAGAATCGTGTGCCTTGGAAAACTAAGGCAGCTCGAAAGCAGATTTCCGAATCCCTGTCCACCTGCTCGACAAGCTCCCCCTACACCACAGATAGTCCTATTACGCCCATGCAGAATTCAGTATCAGCATCTTCGCCTTCATCATCCTCATCCTCTGGTCAAACGTCACCGGAGCACCTCAGTGATATATCCGTAAATCCATGTCGTGGCTTTGGCAGCGATGACAATTTCTCCTCAAAAACTTTGTCCTCTTCTTCCGATGGTCAAAAATCACCAGTTTCCAACGCCAAACTACGGTTTCCGCCCAAGCGCTCGCCCAACAACCAAATCAAGTCCAATGTACCTCTGCGCCGTGGACGACGTCAACGTACAACACATAGTTATATACCGGTTAGGCGAGCGAGGCGCCCCATAAAAAAGACACAGGAAAAGCAGATTGATCAGGAAATCCTCCAAATAGAGCTGACAAAAGCGAACACCATTGAGCTCAGCAGCGAATCAAAAAAGCAATCTGATGAAACAACCGAGAAGTTAGAAACCAAGTTGGTGGAGGCGCCGTCCAGCAGCACTGATGAAACCTTAGAGATTACAGCAAACGGAAGTTCATCAAGGGCAACAGATGATGGTAGCACACCAAGTGAAAAGATGGCGGCGATAGAAACGAAACAGGAATCGGAAATGTTACAGATGAAAAGCTCAAGTGATGAAATGCATCCCGTTAAACTCGATGGATTGCATGAGCTGCCACCGTCTGTGGATCAGTTGAAGAACATTCCCAATGAAATCATTGCAGCGAGCGAAGAAGGGTTAGACAATTCGACTGTAACACCTGCGTCCATATTAAATGAGCCTCAGAGATCTCTCAGTTGCACACAGTTGCCAGTGGTAAGTCCAGTGCAATTTGAGGAACTGACCTCGTCCACGGAACTTAATCAACAAGTGAGATTTGGAATGCCATCTCCTGAGTTCGAAGGCGATGTAAGCTTGACAAATGATGAACAGAACAATTCAGAGTTAGTTGTAAGCATTCCGCTTGAAGCCCTCAATGATGACTTGCAGCGTAAACTCTGCAATGCTGAAACGGATATGGAGGCAGATGGTGATGCTGATTCAGAGCCCAAAGAGCCCGTCGAGGTTGACGATGTGAATAACAATGCAAATGGCGAGAATTTTTGCCAGAGTGCTACAACAGATAGCTTCAATTCTGCTGTGGCACTCGAATCTAAACAAATTGAAGCAGAACCAGGCGGAGATGGGAAGTCATTGGTGGATGATATTGGGCCATTAGAAAGACTGGTGAAATTGCCAGATGAGCCACTGCAACTTGGGGAACTACAAATGCCACGCACAGCTGTAACCGCCATGGACTTCTTGGCCGAATTCGAGAAGCATTGTGAGAAGACATTGAAACTAGAAATGGTTACAGCACCACACGAACTTCAATTGCAAGAGGCCAAGCAACAGATGGAGGTGGAAATGAACGATGTGGAGAGCACACTACATGGCATACTGAATGAGATGCAAGATCAACATCTCTATACGCCTGTTTGCACGCCCATGGATGAATTCTTAACGCCAGCTGATTATGCCCCGCTCACTGAACCGGAATCGTCACCGGAAACGCCAACGCAGTTGCAACAGCAACCAACCACCGATGTGCCTGGCGACACCTACGCACTATTAGACAGAAATGAGAATTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCATTATGATACTCATACAACAACCAGAGTTACAACAGCCAGTTGCATCTGCCAGTAATCCACAACAGGCGCCGCTGCACATCGCATATGCTCCACCACTACCTAATGAGATTCTTGCGTTCCAACAGCATCAGCCTCAATCGGCGCCAAGTCAACAACAACCGCAACAACAACAACAAGAGCAACAGCAGCAACAGCACCCTGAACAAGAATTACAAAATCGTACAGTATTAGGTTTACCGCCAACTGTCGCCCCTCAACCGAAAGGCAAACCGCCAATGTTAAAGTGCCGTTTCTGCCAGAATGGGCCACGTTTCTCCAGCAGCTTGGAATACAGCCGTCATATCATTGAGCTGCATCCGGGTGGAGCGCCCTTTAACTGTCCACATTGCACTCAGGCCTTTGCCGGTCGTAGCAAACGCAATCAGCACATCCTCAGCCACCATGTGGTGCAGCAATTCCATTGCGGCCAATGCTCACAAATGTTTCCCGCTCAACGGGCTCTCGACTTGCATTTGCAGCGCCATCACATGCCACTGGCAACGAACACAGCAACTGACGGAGTTCGCCTAGAGGAGGTTCAGCTTCAAATATCTACCAAGGAGCAAAAGCAGAAGCAGGAGAAGCAACAGCAGAAGCAGGAGAAGCAACAGCAGAAGCAGGAGCAGAAACAGCTGAAGCAGGAGTTGAAACAGCAGAAGCAGGAGCTGAAACAGCAGAAACAGAAGACGCAGAAACAGAAGACACAACAACAACAACAACAGAAGCAATCGCAGCCCCAGACAGTGCAACAGGCATCGCCACCTGCAGAACAACAAAAATGCACACAGCCACGCAGGACGCGCATACTTTGCTGCCCGGACTGCGAGGACTGCTCGTCTGCAACTGGTCGTCATCGTCGCAAGGGTCAGCAATGCGAGGAGCTTAGCAATTTGCAGTCTCCGCCAGCGGTGCCAACACCACCAGCGGTGCCAACACCACCCTCAAACCTTGCCTCGTTGCCATCACCATCGCCACAGTCAGTGCCACTGCCATTGCCACTCTCACAGTCACAGCCACAGCCAATGTGCCCAACGCCGCATATTACATTGCCGTCGCCAGAGCAATCTGAGCCTGACTCAACAACTGCAACGTTGCGACAATTCCGTAAGCGTTGCATTCCCAGTGGTGGCACGTTTACGTCATCGACATCAACGTCAGCAACAACAATGCTATTGGCAACGGCATCACCGTCCCCATCCTCATCGCCATCGTCTTCGACTATGGAAACGAGCGCTACTATAGAAATGAGTAAACTACGGGGTACCCATCAATGTGTTATATGTGAGAAGCGATTTTCGAACATCATTGCGCTGCGCAAGCACCAGCAGCTGGCCCATGATTCCCAGACCACAATGCCATGGGTTTGCTCAATTTGTAAGCGTGGATATAGGAAACGCACCGATATGGATAATCACATGAAATCGCATGAGCCAAAGGGACGGCCATATGAGTGCAATGAGTGTTGGGTGAGATTCCCGGAATTCAAGCAGCTGGCGATGCACAAGTTCACCGTTCATGAACTGATCAAGCCGCATACTTGTGATGAGTGTGGTAAACAATTTGGTACGGAGAGCGCCTTGAAGACGCACATTAGATTTCATGGTGAGCGCGGATTCCAGTGCGAAGAATGCGACGAGTCTTTCGCATATATCAAAGATTTTCGCAAACATCGACGTACCCACAACAGTGCATTATTTTACAAATGTGAACATTGTCCTCGAACGTTTCTACATTTTACGTCATTTCGTGCACATATGAACAGCCATTTGCCGCTGGGTGTATTCCTAAATGATAAATCAACCGCACCGAACCCCATTAAAATGGATAATCCTGGAACGCCATTAATAAACGAGGAATTGCTGCCAATGACGCCGCTGAGCAATTGCAACAGCGGCAGCATCAGTGAAGACTGTCCCGGGTCCGTGGAGGTGGTGGAGAGCAGTGTGGCACAATCATTGGAGATGATCATTGATACGCCATAA
Protein Sequence: MVAKFRRRCVRVQQRLQAFADDIAERKARRRPDKLYQQQQQQTNEADVMEYMHLPESQLERKRRLKSVEPELDAKQAQPAAKEHPPSAKMRRVQLQRRSLPANNNIETETMTTRSLSHQRKVRERVPTRSPQKKNRVPWKTKAARKQISESLSTCSTSSPYTTDSPITPMQNSVSASSPSSSSSSGQTSPEHLSDISVNPCRGFGSDDNFSSKTLSSSSDGQKSPVSNAKLRFPPKRSPNNQIKSNVPLRRGRRQRTTHSYIPVRRARRPIKKTQEKQIDQEILQIELTKANTIELSSESKKQSDETTEKLETKLVEAPSSSTDETLEITANGSSSRATDDGSTPSEKMAAIETKQESEMLQMKSSSDEMHPVKLDGLHELPPSVDQLKNIPNEIIAASEEGLDNSTVTPASILNEPQRSLSCTQLPVVSPVQFEELTSSTELNQQVRFGMPSPEFEGDVSLTNDEQNNSELVVSIPLEALNDDLQRKLCNAETDMEADGDADSEPKEPVEVDDVNNNANGENFCQSATTDSFNSAVALESKQIEAEPGGDGKSLVDDIGPLERLVKLPDEPLQLGELQMPRTAVTAMDFLAEFEKHCEKTLKLEMVTAPHELQLQEAKQQMEVEMNDVESTLHGILNEMQDQHLYTPVCTPMDEFLTPADYAPLTEPESSPETPTQLQQQPTTDVPGDTYALLDRNENXXXXXXXXXXXXXXXXIMILIQQPELQQPVASASNPQQAPLHIAYAPPLPNEILAFQQHQPQSAPSQQQPQQQQQEQQQQQHPEQELQNRTVLGLPPTVAPQPKGKPPMLKCRFCQNGPRFSSSLEYSRHIIELHPGGAPFNCPHCTQAFAGRSKRNQHILSHHVVQQFHCGQCSQMFPAQRALDLHLQRHHMPLATNTATDGVRLEEVQLQISTKEQKQKQEKQQQKQEKQQQKQEQKQLKQELKQQKQELKQQKQKTQKQKTQQQQQQKQSQPQTVQQASPPAEQQKCTQPRRTRILCCPDCEDCSSATGRHRRKGQQCEELSNLQSPPAVPTPPAVPTPPSNLASLPSPSPQSVPLPLPLSQSQPQPMCPTPHITLPSPEQSEPDSTTATLRQFRKRCIPSGGTFTSSTSTSATTMLLATASPSPSSSPSSSTMETSATIEMSKLRGTHQCVICEKRFSNIIALRKHQQLAHDSQTTMPWVCSICKRGYRKRTDMDNHMKSHEPKGRPYECNECWVRFPEFKQLAMHKFTVHELIKPHTCDECGKQFGTESALKTHIRFHGERGFQCEECDESFAYIKDFRKHRRTHNSALFYKCEHCPRTFLHFTSFRAHMNSHLPLGVFLNDKSTAPNPIKMDNPGTPLINEELLPMTPLSNCNSGSISEDCPGSVEVVESSVAQSLEMIIDTP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -