Dfun006320.1
Basic Information
- Insect
- Drosophila funebris
- Gene Symbol
- HINFP
- Assembly
- GCA_018901825.1
- Location
- JAEIFK010000454.1:17348598-17350945[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.016 1.1 9.8 0.1 3 23 121 143 119 143 0.89 2 8 0.017 1.2 9.7 1.6 2 23 162 185 161 185 0.96 3 8 0.00062 0.042 14.2 0.7 3 22 193 212 191 212 0.95 4 8 0.0021 0.14 12.6 0.8 1 23 221 243 221 243 0.96 5 8 4.8e-06 0.00032 20.9 3.2 1 23 247 270 247 270 0.98 6 8 3.5e-05 0.0024 18.2 0.6 1 23 276 299 276 299 0.96 7 8 0.065 4.4 7.9 1.2 1 23 304 329 304 329 0.91 8 8 0.52 35 5.0 4.7 1 23 336 359 336 359 0.95
Sequence Information
- Coding Sequence
- ATGATAAGGCAACCGTCGGGCAAAAGAAAAAAACCCGCTGAGCTGCAGCTGCCCTGTGGCTGGCGAGACTGTCAGGTGATAAGCGATGGCGAATGGTTGCTCAATAGCCACATTACCGTCCATTTGGAGAAGCAGTTCAGTGAACTGGATGAAGAGGACGAGTGCGAATGCACTTGGAACGATTGCAATTTTAAAACAAATTGCCGCGAGGAATTTGAGCGTCACAGCTATTATCATGGCTACTACATTAACCTACTGCTCCATGGCAAGCAGGAATGTGATCGACACCCGGAGATTCCAACGTGCTATGCACCTGCACGCAATGGCGACAAGCTACCCGAACTCAAACAGAACTTCCTCTGCGGCTGGAGCGATTGCAATCGTTCGTTTGTCTCCATTGTCGAATTTCAGGATCACATTGTCCAGCATGCCTCATTCGAGTACGAGATACAAAAGTCACCCGACGACGAACGGCCCAAAACGCAATGCAATTGGAGTATGTGCCACAAGCAGCTGGAGAACAAGTATCGCCTCATCGAGCACATCAGCACACATTCGAACAAGAAGCATGTCGCCTGCTATCATTGCGGCGAACTCTTTCGCACCAAGACGACGCTCTTCGATCATCTGCGGCGACAGCCGGACAACAACACACAAAAGTTCCAATGTGCACAGTGTTTCAAATTCTTTGCCACGGAGAAACTGTTGCGGGGTCATGTGGTGCGGCATGTGAACTGCTACAAGTGCACCATGTGCGACATGACCTGCAGCTCGGCCAGCTCGCTGACAACTCACATTCGGTATCGGCATCTGAAGGATAAACCTTTCAAGTGCAGTGAATGCGATACGCGTTGTGTGAGGGAATCGGATCTGGCGAAGCATGTGGAGATTGTGCACGAGAAGATGGTGCATCAATGTGATCAGCCTGGATGTCAATACTCTGTGCGCACCTACAATCAAATGCGTCGGCATTTTCTGGAGGTGCATGGCAACAATCCGATCTTCTATGCCTGCCACTGCTGTGAGCGTTTCTTCAAGAGCGGCAAATCCCTCTCCGTACATCTGATCAGGAAACATGGCTTTCGCTTACCATCGGGACACAAACGTTTCACATATCGTTTGGATGAGAATGGTTTCTATCGCTTGGAGACGACACGCATTGAGAGTCTGGAGGTCACACAACAGATACTCTCGCCGCAAATTAAACTTGAGACTGAGTTGAATAAACCCCAACCGGGCAGTTGCTATGAGATTGTTAATCCAATCAGCACGGAATACGAGCGCATCATCGTCTCCAACGATGCCAACGAGGCGCATTTGGTGGGCGAGGTGACCATCTCATTGCCCAGCCTCACTGACGACGATCCCTGA
- Protein Sequence
- MIRQPSGKRKKPAELQLPCGWRDCQVISDGEWLLNSHITVHLEKQFSELDEEDECECTWNDCNFKTNCREEFERHSYYHGYYINLLLHGKQECDRHPEIPTCYAPARNGDKLPELKQNFLCGWSDCNRSFVSIVEFQDHIVQHASFEYEIQKSPDDERPKTQCNWSMCHKQLENKYRLIEHISTHSNKKHVACYHCGELFRTKTTLFDHLRRQPDNNTQKFQCAQCFKFFATEKLLRGHVVRHVNCYKCTMCDMTCSSASSLTTHIRYRHLKDKPFKCSECDTRCVRESDLAKHVEIVHEKMVHQCDQPGCQYSVRTYNQMRRHFLEVHGNNPIFYACHCCERFFKSGKSLSVHLIRKHGFRLPSGHKRFTYRLDENGFYRLETTRIESLEVTQQILSPQIKLETELNKPQPGSCYEIVNPISTEYERIIVSNDANEAHLVGEVTISLPSLTDDDP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00599155;
- 90% Identity
- iTF_00537803; iTF_00519468; iTF_00558262; iTF_00608782;
- 80% Identity
- -