Dfun003087.1
Basic Information
- Insect
- Drosophila funebris
- Gene Symbol
- -
- Assembly
- GCA_018901825.1
- Location
- JAEIFK010000682.1:2787596-2792586[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.0011 0.078 13.4 0.3 1 23 141 163 141 163 0.98 2 14 0.00013 0.0089 16.3 1.3 1 23 389 411 389 411 0.98 3 14 2 1.4e+02 3.2 0.7 1 23 417 440 417 440 0.92 4 14 0.28 19 5.9 1.4 1 23 466 489 466 489 0.92 5 14 0.0012 0.078 13.4 1.9 3 23 771 791 770 791 0.92 6 14 0.046 3.1 8.3 1.4 1 23 797 820 797 820 0.98 7 14 0.23 15 6.2 1.4 2 23 857 878 856 879 0.92 8 14 0.00065 0.044 14.1 0.6 1 23 900 923 900 923 0.97 9 14 0.015 1 9.9 0.4 1 23 1173 1196 1173 1196 0.91 10 14 4.7e-05 0.0032 17.7 3.3 1 23 1209 1231 1209 1231 0.98 11 14 0.0028 0.19 12.2 1.7 2 23 1237 1259 1236 1259 0.95 12 14 1.1e-05 0.00073 19.7 4.0 1 23 1265 1290 1265 1290 0.97 13 14 1.8 1.2e+02 3.3 0.1 1 23 1295 1317 1295 1317 0.85 14 14 0.28 19 5.9 1.4 1 23 1323 1346 1323 1346 0.96
Sequence Information
- Coding Sequence
- ATGGCGACAAAACGAGTGAAAACAGATGACATGGAAGTGAATTACAAATTTTCGTGTCGCTGTTGCCTGAAGTCCGAGGCGGAATTCTTCAAGCTGGACTCCCTCACAGAGAGTGTCATAGGCGACAATGACGAGTGCCCAACGAAAATTCCGCTCATACGTTTGCTATTATTCTGTATACGCACTGAAAATTTACCCGAGCTGCCGCAGTATATTTGCGTGGAATGCAGCAAGAGCTTGCAAATTGCTTACTTTTTCATAAAAAACAGTCTCAGGGCACATGAAATACTGTGTCGCAAGCTATGCCCTGAGAAGCTGAAGAGTACAATGCGTTTTAACGGCAAACAACTCTTCGAGGAGAACATAAATGACGTGAAATTGGGTGTTCATAAAGCGAAACCTCTTAAGGCCGCCGTTCGCCACGAATGCAAAGTATGTGGCGCCATTATATATGATCGAATGGAACTCAAGCAACACATTCGTATGCACACAGAAGAGTCACAGCATGCATGCAAGTTATGCAAATTTGTGACGCTTAACCAGCGTCAGCTACCACTGCATTATCGAAAGGTGCATAATTTGACGGCTGCCGAAACTCATCAACAACTTAAAATCCAAAGGTCTATACAGGCGGCTGCTATCGCTACAAATATGACAAGTTCAACAGCAATTGATGATGATGGTCAGGTGAAGGTATGCACACTGGAAGATATGGAGCTGCTGATACCCACTGTGCTAAGGCCGGAAGACTTCTCGCGTCCACAACTGGATATAGATCAACTGCGTGATATTGAACAACAACTGAATAACTCATTGTCGGTTGGCGAGTCTGCTTCAGGTTTTAGCTCCACTGCTATGCCGATCGAACCAACGATAGCAACGGGCGACAGTGCCAATATGAGCATTGGTGCGCAATTTCTAGTCATGCCCGATGGATCGTTACAGCAAGTCAATGATGGCGGAGTTGTTTTCGAGTACATCGATGATAGTAAGACTACAACAACGACCACCAATATAAGCCTACAGAACTTATTTGATGACTCCAAACCAGCGGTGTCTTATAATGCAATGGATATTGATGCGAACTACTTGGGGGATGCGCTGCCACAGATAACTGTGAAGCCACCACCAAGACCAGGTCCAGGATCAATAGCCGCCCTGAAACACAAATGTAAACTGTGTCCCAAAGCATTTCCCACGGTAGCACGTCTCAAGTCTCATCAGTTAACCCATAGTCATTTGCCCAAATTCTATTGTGATCAGTGCTCCTACTACTCGTTGCGCAGTGCCGATCTCATCCAACATTACAAGGAGGAGCACAAGTCTTCTATTGGTGATAATAAACATTATCTCGAAAAATCATCCCTGTCACTATCAAGAGACAGGAGTCGCATATATTCCTGCGACATGTGCTTATTTGAGACACCGAGCAGTTTCCAGCTACGAAAACACTACAGTGATAAGCATCTGATACACCCCAGTGAGGTACAGCTGCGTCCCAGCTGGACCAGTGAGTCCAAGGATACAGGCGCTAGTTCGACAATACTCAGTGGCAGTAACCGAAATCAGTTGACGAATTCACAACCACATATTCCGCTGGGTATTAAATATCCATCAACGTCGGCTGTGCAAACAGCTGAAACGACAGCGATAACCGTGTCGACAGCAACCACAGCGTTGCAGCTAAATCCACCACAGTCAACAACATCGGCTGTAGGAACGTCTGCTGGTGACATAAATGTCGTCGTGGATGCAACTTCGTTGTTCTATGCAGCAACGGCAGATTCAAATGATACGACGGTCGCAGCGAAACCAATTGTAACGGAATCCAACGCATTTGCAATATTCCCAGATCCATCTTTTGCTAACCACATGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACTCCAACATCTTTGGCGATATGCAAGATTTTATTGATAACACCGATGTGGCAGCTATTTGTACCATACCCGCCGACGATATGCCTGTCGTCGATGGCGATGACATTGTTATCGATAACAATAATATGAGCCTTGATTTTGATGCTGAGAATCTATTCGAAGACTTTGAAGAGGATGTTGAAGTTGGCGAAGAGGATGACGAGGATGAGGAAGATGCCGAAAATGATGATGAGAACGACAATAATGATGCGGCTGCTGATCAAAATTTATTGCTTACCAGCGATGATGACGACGTCGATGACTTTGATGATGAGCAATCGAAGCATCTACAGAAACCATATTGCATCTATTGTAACAAAAAGTTTACCAGTCAATACAAGTTCGAGAATCATATGTTCGTACATCGCGGTTTGGCGCCGTATCGCTGTGAGCTCTGCACGAATCTTTACAATATGAAGCGTCTGCTTATACGGCACTACAAAACGGTCCACAAGCGAATGCCCACTCGGGACATGGTACAGGCCAAGGGTGATAAAGTGGCAGTGGAGCGTAGTGCCATAGAAAAGCTGAACATCAATGTTGAGCAGGATCCCATGCTGATGTGTGCTAAATGCCCTTTTGAATGCGAGCAGGAGGGTGAGATGCGGAGGCATCTGAATGCGCATCATGGCATCAACGATGGCGTCTCTGTACACGCTAATGAGGTGTTTATCATTCGCAAATTGCCTTATGAGTGTCCACGCTGCATTCGCTCATTTGCGGCCAAGAGTACGCTGACTCGCCATTTGCAACGGAGTCATTTAGTAGACACAATCATTGAGATGCAGGCGCCTCAATTAACAACTAGCTCAGCGACAACAACAACCACATCGACAGCTACAACTACATTGCCGAAGAATGCCGGTGATGGCTGCGGTGACAATAAAGGAACAACAAGGCCGCAGGAGTCCTGTTTGATGAATACTTTGTCGCACCTTGTTGACTTTGGCAATGCTGATGGCGAAGGCGATGGTGATGGCGATGGCGATGGCGATGGAGATGGCGATGGCGATAGCGATGGCAATGGAAAATGCGAAGCCAGAGATATAAACAGTGACACAGGAATAGAAGCGAATAATGAAGATATAGACACAAAACCATTAACGACAACGTCAGGATTAGCAACAACCGAAGATGATAATAAAACTGAGACAAGAACTGATGAAGCGTCCCCTGAAGATGCTATTTTAACAACAAGGTCACGATCAACAACGCCGATAACAACGTCAGTATCAGCAACAACAACATCGTCTACGCTAACAACAGATAAAACACCAACAACAACAACAGTAGGCTCCACATTATTTCCAACGCCTACGCCATTTGATTTTGATCTCGATTTTATTGGCAATGGATCACATACCGCTTCACTTAAAACCAACAATGATACCTTCAACGTTATACCAAGCGCCAGTCCATTGCTAAACGGCAGCGACAAACTATTGACAGCAGCGTTGGAGCCATCGCCGATTAAAGACTTACGTCCGAGGCTTCCACGTACTCCCATTTTTGTGTGCAAGCAATGTAACCAGACATTCGACGAATTGGGTAAGCTGCTGCAGCACGAATTGGAGCAACATTCCAGCGGGACTGTTTCGCCACGCACCATTTATCAACATCAGTGCGAAATATGCAACACTTCATTCCGAACAGTGACGCTGCTTAATTATCATATGAAAAAGCATGCTTCGCGCAAAGTTCAATGTAAACAGTGCCCCAAGGAGTGCAGGTCCAATTCGGAAATGGAGCAGCATGTAGAGTCGAAGCATGCCACAAAAATGCCCTTTAAATGTGGAATCGATGGTTGCAATAAGTCATTCAACTACAAACAACATCTGAAACGTCATCAGAAAACTTCTCATGCAACCGATCAGTATATATGTTCTGAGTGCGGACGCGATATGTTGAACAGTCTCGGCCTGAAGAATCATGTGGCTACCCACAAGGCGTCACATGTATATAAGTGTCCTAAGTGTGTTCGAATTTATTTGAGACGCAAACCTTTTCGAAAACACGCGCAGCGTGAACACAAATGGGATCTGACTGAAGACGAAATGGACAAAATACATTGCTCGAATGAAACACAGCCCTCGATACAAATACGCGAACTAAGATCGGGGAAGGTTGAAAATGAGCAATCTGATTAG
- Protein Sequence
- MATKRVKTDDMEVNYKFSCRCCLKSEAEFFKLDSLTESVIGDNDECPTKIPLIRLLLFCIRTENLPELPQYICVECSKSLQIAYFFIKNSLRAHEILCRKLCPEKLKSTMRFNGKQLFEENINDVKLGVHKAKPLKAAVRHECKVCGAIIYDRMELKQHIRMHTEESQHACKLCKFVTLNQRQLPLHYRKVHNLTAAETHQQLKIQRSIQAAAIATNMTSSTAIDDDGQVKVCTLEDMELLIPTVLRPEDFSRPQLDIDQLRDIEQQLNNSLSVGESASGFSSTAMPIEPTIATGDSANMSIGAQFLVMPDGSLQQVNDGGVVFEYIDDSKTTTTTTNISLQNLFDDSKPAVSYNAMDIDANYLGDALPQITVKPPPRPGPGSIAALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYKEEHKSSIGDNKHYLEKSSLSLSRDRSRIYSCDMCLFETPSSFQLRKHYSDKHLIHPSEVQLRPSWTSESKDTGASSTILSGSNRNQLTNSQPHIPLGIKYPSTSAVQTAETTAITVSTATTALQLNPPQSTTSAVGTSAGDINVVVDATSLFYAATADSNDTTVAAKPIVTESNAFAIFPDPSFANHMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSNIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNMSLDFDAENLFEDFEEDVEVGEEDDEDEEDAENDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVAVERSAIEKLNINVEQDPMLMCAKCPFECEQEGEMRRHLNAHHGINDGVSVHANEVFIIRKLPYECPRCIRSFAAKSTLTRHLQRSHLVDTIIEMQAPQLTTSSATTTTTSTATTTLPKNAGDGCGDNKGTTRPQESCLMNTLSHLVDFGNADGEGDGDGDGDGDGDGDGDSDGNGKCEARDINSDTGIEANNEDIDTKPLTTTSGLATTEDDNKTETRTDEASPEDAILTTRSRSTTPITTSVSATTTSSTLTTDKTPTTTTVGSTLFPTPTPFDFDLDFIGNGSHTASLKTNNDTFNVIPSASPLLNGSDKLLTAALEPSPIKDLRPRLPRTPIFVCKQCNQTFDELGKLLQHELEQHSSGTVSPRTIYQHQCEICNTSFRTVTLLNYHMKKHASRKVQCKQCPKECRSNSEMEQHVESKHATKMPFKCGIDGCNKSFNYKQHLKRHQKTSHATDQYICSECGRDMLNSLGLKNHVATHKASHVYKCPKCVRIYLRRKPFRKHAQREHKWDLTEDEMDKIHCSNETQPSIQIRELRSGKVENEQSD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -