Basic Information

Insect: Drosophila funebris
Gene Symbol: ken1
Assembly: GCA_018901825.1
Location: JAEIFK010000122.1:2780890-2783274[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.063 4.3 7.9 5.9 3 23 248 268 246 268 0.96

2 12 0.00085 0.057 13.8 0.5 1 23 274 299 274 299 0.94

3 12 0.0018 0.12 12.8 1.2 1 23 306 331 306 331 0.93

4 12 0.0015 0.1 13.0 4.1 1 23 341 363 341 363 0.96

5 12 0.0018 0.12 12.8 2.2 1 23 370 392 370 392 0.97

6 12 0.0068 0.46 10.9 0.5 1 23 398 420 398 420 0.97

7 12 0.05 3.4 8.2 2.6 1 23 426 449 426 449 0.97

8 12 0.018 1.2 9.6 4.1 1 23 455 477 455 477 0.95

9 12 0.02 1.4 9.5 2.6 2 23 484 505 483 505 0.95

10 12 0.00017 0.012 16.0 0.8 1 23 597 620 597 620 0.95

11 12 0.00035 0.024 15.0 0.8 1 23 626 648 626 648 0.95

12 12 9.3e-06 0.00063 20.0 2.3 1 23 654 676 654 676 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.063	4.3	7.9	5.9	3	23	248	268	246	268	0.96
2	12	0.00085	0.057	13.8	0.5	1	23	274	299	274	299	0.94
3	12	0.0018	0.12	12.8	1.2	1	23	306	331	306	331	0.93
4	12	0.0015	0.1	13.0	4.1	1	23	341	363	341	363	0.96
5	12	0.0018	0.12	12.8	2.2	1	23	370	392	370	392	0.97
6	12	0.0068	0.46	10.9	0.5	1	23	398	420	398	420	0.97
7	12	0.05	3.4	8.2	2.6	1	23	426	449	426	449	0.97
8	12	0.018	1.2	9.6	4.1	1	23	455	477	455	477	0.95
9	12	0.02	1.4	9.5	2.6	2	23	484	505	483	505	0.95
10	12	0.00017	0.012	16.0	0.8	1	23	597	620	597	620	0.95
11	12	0.00035	0.024	15.0	0.8	1	23	626	648	626	648	0.95
12	12	9.3e-06	0.00063	20.0	2.3	1	23	654	676	654	676	0.98

Sequence Information

Coding Sequence: ATGAATGAGGGGAGTGAATACTCCATACACTCGATATGCCGCATTTGCTTAAACCACCTGCGAAACGATGCGGTCTACGACCTTTTCCTCGTCCCGGGTCTCGCCAAGAAACTGTGTGTGTGCACTTCACTCTCAGTGGAGCAGCACGATGGCTTTCCGAAAAACCTATGTACCAATTGCTACACCAAGCTAAATGACTTGCATGGTTTCCAGAAGATGTGCGTGGATTCTGTCCAAAAGTTCCAAGATATGGTGGCCAACAATTACTTCACGCCTGTCATTTCGGATATCAATCAAATTGACAATGTTGATGTTCTGAATATTGCGCCACCCGAGGGTGAAATGGAGGAAGATCGCATTAACTTTGATCCGCTATTGAATACGAAAGTAGAAATCATTGAGAATGAGGATGATGTATTTAAAATGCTTGAAGATGTCGACAGGGAAGTCGAGGATGTTGACAAGGAGAAGGAGTCGTCCTCGGAGAGCGAAGAGGAGATTGAAGAAGAGGATGGTGACTTTGAAGCGAATAGCAGTGAATCGGACGATGCAATGCCTCTGTCACGTTTGCGTGGTGGTACCAGAGCTTCAAAGGCCAAGGCCAGAAAGGCTGCTGCGCGAAATGAAAGCGACGAATCCTCTAGCTCTGATTCGTCTGATGATGACGAGGATAGGTCCAGTTCAAAGCCAAAACGCAAACGTATTCCGGCTACCGAGCGGGATCGTCATCGTCTTATTGACTGCCACATTTGCCATCAGAAGTTCAAGAAGGCAATTCGCTACGAGGAACATATGAAGCATCATAATGATCTACTGCCATTCCAGTGCACTGTGGAGAGCTGCAAGAAGGGTTTCACTACCGCTGGTGGTCTCCGTCTGCACATGGACCATGCGCACATTGAATTCTCTGAGGTGCATGCCTGCACCTTTGAGGGATGCGACAAGACATTCCCCCGATCCGTCTTGCTCACGTTCCACATGAAAAAGGTGCACAAAGTGGCAAAGCCTGATATTAAAAAACATGCCTGCACCGAATGTGAGAAAGTTTTCCGTTGTCCAACAGCACTTAAAAAGCATATGTATAAACACACTGGCGAGGAGCTGCCATTTGCCTGTGAGATCTGCGGCAAACGATTTCACATACACAGCGTCCTCAGGGATCATCTCTTGCGGCATGCCGGCGTCAAGAATCATGTGTGCCCCTACTGTGGTGTGGGCAAGACAACGCGTCAGGAGTGGAACAAGCACATATTAACGCACACCAGGGAGAAGCAGTTCCAGTGTCGTCAATGCGATCATGCCTCCCACAACAAACAGGCTCTGTCCAATCACGTCAAGGTGGTTCACATGAAGATCAAGAACTTTGCCTGCCAATATTGTGGCAAGACGTTTGGCAAATCCCATGCCTGCAAGATCCACGAGAGACTGCACACTGGAGAGAACTGCTGCGAGTGCAAGATCTGCGGCAAGATCTTCCTCTTCGAGAAGAGGCTGACCAAGCATTTGCAGTTACATGAGAAGCGTGATATACCGCCGGCGTCAACAGCAGTAAAGCCCCAAGTTGATGGAGATGGCCAGAGCACACCGGGTGTGAGCCAGGAGCAGAATCATCTAACAGAGCCAGTGGACGTTAAGCCTTTGCCAGTTGTCCCACCCAAGCCTAAGAACTCGCATCGAGTTGAGCGTGTGGATATATCTCAGCTTGCCGGAACGTCTGTTAATCCGATATCATCGGTGTCGGTGCCGTCGTGGTCGCCACAGGTGAACTTCACCAAGAAGGAGGGTCAACACATTTGTCCTGGCTGTGGCCGAGGCTTCAATCACATTGGCAACATGAAGCTGCACTATAAGATAATACACGAGAAGGTCAAGGACTTTGCCTGTCGCTATTGTCCCAAACGCTTTGCAAAGGCCCAGTATCTGCGCAATCATGAGTATATTCACACAGGCGAGAAGCCATTCGAATGCAAGATCTGTGGCAAACACTTCCGGCAGGAGCAAGTGTTGAAGACGCATCTAAAGGTGCACGACAAGCCGCCGAAGCAGCCCAAGGAGAAGAAGCCACCAAAGCCATCAGTTAGTAAAGCCCGAGGCTTGAAGGTTGAGCTCAACAAAAAACAACCAAAGATTCATGACGAATATCAGGATCCGGCGGCCGAGCGGGCGGCGGCCACAGCCGCCCTGCTGGCCCAACAGATCGAGGAGAATGAAGCAAAGCGAAAGCAGGAGGAGGCAAATCGTAAGATACAAGAGGCCGCCTGTGAGCAGCTGAATCGGCTGCAAAAGCAAATACAGAGCGAGAAGGGCTCCTACGACAGCTACTATGGACAGAAAACGGAAGCCGAGGGCATCAATCCGGATACACTTAAATTAGATCACGTTTAA
Protein Sequence: MNEGSEYSIHSICRICLNHLRNDAVYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCTNCYTKLNDLHGFQKMCVDSVQKFQDMVANNYFTPVISDINQIDNVDVLNIAPPEGEMEEDRINFDPLLNTKVEIIENEDDVFKMLEDVDREVEDVDKEKESSSESEEEIEEEDGDFEANSSESDDAMPLSRLRGGTRASKAKARKAAARNESDESSSSDSSDDDEDRSSSKPKRKRIPATERDRHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVESCKKGFTTAGGLRLHMDHAHIEFSEVHACTFEGCDKTFPRSVLLTFHMKKVHKVAKPDIKKHACTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFHIHSVLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTREKQFQCRQCDHASHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQLHEKRDIPPASTAVKPQVDGDGQSTPGVSQEQNHLTEPVDVKPLPVVPPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRYCPKRFAKAQYLRNHEYIHTGEKPFECKICGKHFRQEQVLKTHLKVHDKPPKQPKEKKPPKPSVSKARGLKVELNKKQPKIHDEYQDPAAERAAATAALLAQQIEENEAKRKQEEANRKIQEAACEQLNRLQKQIQSEKGSYDSYYGQKTEAEGINPDTLKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610124;
90% Identity: iTF_00608675;
80% Identity: -