Basic Information

Insect: Drosophila funebris
Gene Symbol: RREB1_1
Assembly: GCA_018901825.1
Location: JAEIFK010000455.1:3122790-3137060[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.028 1.9 9.0 0.8 1 21 103 123 103 125 0.93

2 12 0.0029 0.19 12.1 0.1 1 20 135 154 135 156 0.95

3 12 0.063 4.3 7.9 2.9 2 22 239 259 239 262 0.89

4 12 0.029 2 9.0 0.1 1 23 434 456 434 456 0.97

5 12 9.8e-06 0.00066 19.9 0.7 1 23 466 488 466 488 0.99

6 12 0.00066 0.045 14.1 2.0 1 23 494 517 494 517 0.97

7 12 0.0086 0.58 10.6 0.7 1 20 810 829 810 831 0.94

8 12 6.8e-05 0.0047 17.2 0.3 2 23 1187 1208 1186 1208 0.97

9 12 0.11 7.8 7.1 6.3 1 23 1214 1237 1214 1237 0.97

10 12 3.6 2.4e+02 2.4 3.6 1 23 1377 1400 1377 1400 0.79

11 12 0.0067 0.45 11.0 0.5 3 23 1463 1483 1461 1483 0.96

12 12 0.0011 0.072 13.5 4.8 1 23 1489 1511 1489 1511 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.028	1.9	9.0	0.8	1	21	103	123	103	125	0.93
2	12	0.0029	0.19	12.1	0.1	1	20	135	154	135	156	0.95
3	12	0.063	4.3	7.9	2.9	2	22	239	259	239	262	0.89
4	12	0.029	2	9.0	0.1	1	23	434	456	434	456	0.97
5	12	9.8e-06	0.00066	19.9	0.7	1	23	466	488	466	488	0.99
6	12	0.00066	0.045	14.1	2.0	1	23	494	517	494	517	0.97
7	12	0.0086	0.58	10.6	0.7	1	20	810	829	810	831	0.94
8	12	6.8e-05	0.0047	17.2	0.3	2	23	1187	1208	1186	1208	0.97
9	12	0.11	7.8	7.1	6.3	1	23	1214	1237	1214	1237	0.97
10	12	3.6	2.4e+02	2.4	3.6	1	23	1377	1400	1377	1400	0.79
11	12	0.0067	0.45	11.0	0.5	3	23	1463	1483	1461	1483	0.96
12	12	0.0011	0.072	13.5	4.8	1	23	1489	1511	1489	1511	0.99

Sequence Information

Coding Sequence: ATGCGCAATGTTAATGCTGCTGTTATGTTCATGTTAATGGGCAACGATGATAGTGCTGGTGTGAGTGTGAGCTCGGGCTTCGTTGATGGCAGCGCTCATAGCGGTTATTTGCTCAGCAGCAGCGCCGCCAGCAGCGTACAGTCAGCGTCTGCGTCAGCGTCAGCGTCCGCGTCGACAGCGGCAGCGGTAACAGCCGCTGTTGCGGCGCAGCAAGCGTCATCGAGCAGCTCGGGCGGCTCATCGCCACATGGTTTGTGCCACTCCAGTGCCGAGTCGGGCATTGGCGCCGGCGATGATCACATGAAATATCTGTGCCCCATCTGTGAGGTTGTCTCGGCCACGCCCCATGAGTTCACCAATCACATACGTTGCCACAATTATGCCAACGGCGACACTGAGAATTTCACCTGCCGCATTTGTTCGAAGGTGCTGTCATCGGCCTCGTCGCTGGACAGACACGTGTTGGAGGAGGAACTGGAGCTGGAGGAACAGCACGAGGATGCCTCCGATGTGGACAGCATGGATGAACATGTGGCACAGCTGATAACCTCGACACCCGATGTGGCAACCCTACTTGCCTCCGGCGGCAGCACACCCAGTCAATCACCCGCCCCACCGATGCTCCTCAGTTGCCCCGCCTGCCCGGCCGATGAGTTTGATTCCTTGCCAGCATTGTGCCAGCATCTGGACGCCCAGCATGCGGATATACCCGCCAAGTGTCGCGACTGCGATGTAATCTTTGCAACGCATCGCCAATTGCAGACGCATGGATGTCGTGGCAGTCATGGCATGCAAATGATGCCGCTGCTTGGGGCAAGCTCGAGTCCCATACACAAAGTGGAGCAGGAGGAGGAGGAGGAGGAGGAGGAGGCGGAGGAGGTGGAGGTGGAGGAAGAGTTGGATATGGATATGGAGGAGGAGCACGAGCAGGAGGAGGGTGAGGAGGATGAGGTTAACGGTGTGGGTGTGGGTGAGGAACAACAACCAGCCGAGCAAGCGGAACGAGATGACTTCTTTCAACAACTCTACCTGAAAAACAAGGCGAACATTGCTGCTTCGCTGCCCTCGCCGATCAAACATGAGGTCCCCGATCGGGGTGACATTCGTCACGATTTGGCCGACATTCAGAGCATCCTCAACATGACCAGCTCCAGCTGCACATCGAGTTTTCTGCGCAACTTTGAGCAATCGGTGAACACCCCCTGCTCCAGTCAATACAGTCTCGATGGACGCGATGGCGACGAGGAGGCCCAAGATGCCTTCACCAGCGAATTCCGACGCATGAAACTGAGAGGCGAATTCCCCTGCAAACTCTGCGTGGCCGTCTTTCCCAATTTGCGCGCCCTGAAGGGACACAATCGTGTCCACCTGGCGGCAGTTGGTCCAGCCGGTCCATTTCGTTGCAACATGTGCCCCTATGCCGTCTGCGATAAGGCCGCCCTGGTGCGGCACATGCGCACCCACAACGGCGATCGTCCGTATGAATGCGCCGTCTGCAATTATGCATTCACCACGAAGGCCAATTGTGAGCGGCATTTGAGGAATCGGCATGGGAAGACCAGTCGGGAGGAGGTTAAGCGTGCCATTGTCTATCATCCGGCTGAGGATGCCAGCTGTGAGGAGTCCAAATCCGCCCAAAGATTGCACGATTCAGAACTGGGTGAGCTAAGCTATCGTTCGGTGTCGCCGCCGTTGAACAATGTGGAGACTGCCTCGCAATTGAAGCACATGTTGCTGGCCGAGCCGCCGAGCACAGTTGCTCCGAATGCGGTGGCAACAGTCGCAGCAACAACAACTGCTGTTAAGGCTGCGCCCTTGAAGATACAGGTGAAGAGTCTGGATCAATTGGTGGATAAGCCGTTGGCGCCTGCTTTGGATCTCAGCATGGATGTCTTGGATCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCATTGCCACCTCCCCATCGGTTGCATCATTGGGTCTCCCATTGCCGATGCCCGTGGGCGTGGGCGTGGGCGTGCCTGTGCCCGCTGGTGGACCCGTCAAAATGGTCATCAAAAATGGCGTCCTAATGCCAAAACAAAAGCAACGTCGCTACCGCACCGAGCGACCCTTTGCCTGTGAACATTGCTCGGCTCGTTTCACGTTGCGCTCGAACATGGAGCGTCATGTGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCGCACATCTCCGATCAGGTGAAGTATGCCATACTGGCACAGCAATTGAAGGCACGCAAGGATACAGACTTGTTGCAGCAGGCGTTGGCACATGGCTCCAGCAGTGTGGCAGCCAATCCTCTGCTGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATGATGAGCCGCCCAAGTTGATCATCGATGAGGATGATGAGGAGGAGGAGGAGGAGGATGGCTTGGAGGATGAGCTGGATGAGGAGGAGGAGGATGAGCTGATGGAGGAGGATGAGCCCGAGCAGCTGCTGGATGAGGAGCAGGAACAGCAGCAACGCCAGCCAACACGCAGTTCCACGCCCATTGAGCGAGAAGCGGCCAAAAAGGTGGCCGAAACTATCTTGGAGCAGGCCATCAAAGCAGGCAAATCCATGGACAGTGTGACCGCGCTGGACTCCAAGAAGTTGCCACACAAATCGCCGATTCCAACACCCACGCCCGCCCCAACGGCAACAACAATGAAAACCATGATCGCCCAAGCGGAATCTGTGGCCAAATCCCTGAAGGAAGTGGCCAGCTCACCGTTCAAAGATGAATCTCAAGATCTTGTGCCCGTTTCGAAGCTGGTCGACAATGCCACCAGCAATCAGGTGTCCTTCAATAGCTACTTTCGTCCCAGCGATGTGGCCAACCACATGGAGCAATCCGATGAGGAGGGTCTCGTTGCCTCCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGATGTCACCAGCAGCAGCAGCAATGAGCCCAAAAAGAAGTCGGCCTACAGCCTGGCCCCCAATCGTGTCAGCTGTCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCAGCCTAAGGCGTCACATCCTAACGCACACGGGACAGAAGCCCTTCAAGTGTTCGCATTGCCCACTGCTGTTTACCACCAAGAGCAACTGTGATCGCCATCTGTTGCGCAAGCATGGGAATGTGGAGAGTGCGATGTCTGTGTATGTGCCCACCGAGGATGTGAGCGAGCCGATACCAGTGCCCAAATCGGTGGAGGAAATCGAGTTGGAGGAGCAGCGACGCCGCAAGGCAGAGCAGCTGGAGCGGGAGCGGGAGCGCGAGCGTGAGAAGGAGCGGAAGCGAGAGCGGGAAAGGGAATTGGAATTGGAAAGGGAGCGTGAACTGGAGCGGGAGCGTCGCCTGTTGGAGCAGGAACGTGAACGGGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCGCCTCATCGCCCACCGCTGCTGGAAGTCCGCCAGCCCCCGCCAGTGTCGCGAGCGAGTCGCAAGGCAGCGATCTGCCCTACAAATGCCATCTCTGTGAGTATTCGTTCGGCGAGCGTCTGCAGTGCCTGGAGCACATCAAGCAACAACATGCACATGAGTTTGCGCTGTTGCTGGCCAAAGGGGCCATTGAAACGGAGGAGCAACAGTTTCCAGCGCCAGCGCCACCACCACCAGCGCCAACAGCAGCAGCAGCAGCAGCAACAGCCTCCGATGAGGAAGCTGGTCTCGCCTCACGTGCCGTCAAATATCCGGACTATAGCAATCGCAAGGTGATCTGCGCCTTTTGTGTGCGTCGCTTTTGGTCCACCGAGGACTTGCGTCGTCATATGCGCACACATTCGGGCGAACGTCCGTTTCAATGTGAGATCTGTTTGCGCAAGTTCACATTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGTGGACGCAGCCACAACGGCGATATGGGTGGCCAGTCCGATTGCTCGGATGATGAGCAGTCGCAGTCTGCCACGCCGCCCACAACACCCACGCCAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCAAGTTGCATGAACTGTTGGACAAGGCGAACGAATGGCGCGTGAGTCGTTTGGGTGAGCACAAGGAGAACATCGCCGAGGCTGCCACACCATCGGCGGCAACAGCAGCAGCTGCCGCCGCCGCCGCCGCAGCAGCAGCAGCAGCTGTTGCAAGTGGCGATCTAATTGGAAATTTGCTGGGCATCAGCGATCAGGGCATACTCAATAAGCTCCTGTCCTCGGCCGATGAGGCGGCTAAGCTGCTGGGCGTGGACAAGTAA
Protein Sequence: MRNVNAAVMFMLMGNDDSAGVSVSSGFVDGSAHSGYLLSSSAASSVQSASASASASASTAAAVTAAVAAQQASSSSSGGSSPHGLCHSSAESGIGAGDDHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLEEELELEEQHEDASDVDSMDEHVAQLITSTPDVATLLASGGSTPSQSPAPPMLLSCPACPADEFDSLPALCQHLDAQHADIPAKCRDCDVIFATHRQLQTHGCRGSHGMQMMPLLGASSSPIHKVEQEEEEEEEEAEEVEVEEELDMDMEEEHEQEEGEEDEVNGVGVGEEQQPAEQAERDDFFQQLYLKNKANIAASLPSPIKHEVPDRGDIRHDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGDEEAQDAFTSEFRRMKLRGEFPCKLCVAVFPNLRALKGHNRVHLAAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEESKSAQRLHDSELGELSYRSVSPPLNNVETASQLKHMLLAEPPSTVAPNAVATVAATTTAVKAAPLKIQVKSLDQLVDKPLAPALDLSMDVLDLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIATSPSVASLGLPLPMPVGVGVGVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAHISDQVKYAILAQQLKARKDTDLLQQALAHGSSSVAANPLLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDEPPKLIIDEDDEEEEEEDGLEDELDEEEEDELMEEDEPEQLLDEEQEQQQRQPTRSSTPIEREAAKKVAETILEQAIKAGKSMDSVTALDSKKLPHKSPIPTPTPAPTATTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVSKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAEQLEREREREREKERKRERERELELERERELERERRLLEQEREREXXXXXXXXXXXXXXXXXXXXXXXXXXXXXASSPTAAGSPPAPASVASESQGSDLPYKCHLCEYSFGERLQCLEHIKQQHAHEFALLLAKGAIETEEQQFPAPAPPPPAPTAAAAAATASDEEAGLASRAVKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGDMGGQSDCSDDEQSQSATPPTTPTPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKLHELLDKANEWRVSRLGEHKENIAEAATPSAATAAAAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -