Basic Information

Insect: Drosophila funebris
Gene Symbol: Znf574
Assembly: GCA_018901825.1
Location: JAEIFK010000682.1:1315717-1317911[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.057 3.9 8.0 0.3 2 23 323 345 322 345 0.95

2 10 2.2 1.5e+02 3.1 0.2 6 23 355 372 355 372 0.97

3 10 3.4e-05 0.0023 18.2 0.5 1 23 378 400 378 400 0.98

4 10 7.7e-05 0.0052 17.1 1.4 1 22 414 435 414 437 0.89

5 10 0.00017 0.012 16.0 1.0 1 23 445 468 445 468 0.97

6 10 1.7e-05 0.0012 19.1 1.1 3 23 476 497 474 497 0.92

7 10 0.0061 0.41 11.1 0.4 2 23 509 531 508 531 0.97

8 10 8.2e-05 0.0056 17.0 3.1 1 23 538 561 538 561 0.93

9 10 2.2e-06 0.00015 21.9 1.2 1 23 567 589 567 589 0.98

10 10 5.3e-05 0.0036 17.6 1.4 1 23 595 618 595 618 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.057	3.9	8.0	0.3	2	23	323	345	322	345	0.95
2	10	2.2	1.5e+02	3.1	0.2	6	23	355	372	355	372	0.97
3	10	3.4e-05	0.0023	18.2	0.5	1	23	378	400	378	400	0.98
4	10	7.7e-05	0.0052	17.1	1.4	1	22	414	435	414	437	0.89
5	10	0.00017	0.012	16.0	1.0	1	23	445	468	445	468	0.97
6	10	1.7e-05	0.0012	19.1	1.1	3	23	476	497	474	497	0.92
7	10	0.0061	0.41	11.1	0.4	2	23	509	531	508	531	0.97
8	10	8.2e-05	0.0056	17.0	3.1	1	23	538	561	538	561	0.93
9	10	2.2e-06	0.00015	21.9	1.2	1	23	567	589	567	589	0.98
10	10	5.3e-05	0.0036	17.6	1.4	1	23	595	618	595	618	0.97

Sequence Information

Coding Sequence: ATGGCCGCCTGTGTGCTTTGTTTTGGATGCTGCAAAGTCGGCGAGTCCTATAAGATATTTTCGGAGGCAGGCTTGCGGCTGAATATTTGCAAAACAATAAACAAACATTTTTGGCTTGAGCTGAGCAGCGCTGGGGGCGAACGTGAGGAAATTTGCCATCAGTGCTGGGAATGTGTGAGCAGCTTCAATATATTTTACCAGCGCGTCTACAATGTGCATCAGGAGCGGCGGGAAATCAAGAATGTGCCCATCGAATTCTGTGTCGATACGGAGGCGGCTAATCCACTTGCCTTTGGTGCTGAATTGGATGCACTGGCAGAGGATTTCTTTGCATCTGATAACGTCAAGGTAGAGGTGAACGAGCTGGAACCGTTGCCCAAGCTGGAAATGCTCGAGGAGCCCGTGCTTGAGGAAACGAAAGCCACAAAACGCGCCTGTGCCGAATATCCAGAAATTGCAAAGCGACGCATTAAAAAGGAGCAAATAGTGGCCACCAGTGACTCCGATGGGGATAGACCATTATCTGAGTTCCTTGACCTGAAGAACAATAGAAAACCTTCAGCATTACGGGACAGACAACTGCGTAGGAGCTCTCGCCGTGGCTGCAGAGCGAAAACACTGCCAGAATCACCCTCAAGAAATTTAAAGAAGGAGTACGTGAGCGACGAGGAGCTTGATAATGATAATGATACAGATTTCGTAACGCCTGAGGCAGTGTTAGGCACCGATGACAGTGAGAGCTCTAGCGAAAGCAGCGATACCGATTCTGGGGACAGTTTGCCCGACGTCGAGCCAGAGGAGCGCTACGCAGAGATTCCCAAACGCGTTGTAGTCAAGCCCAAAAAGTATCGAAAACGTCCCAAACCGTTGGTGCCACCCGTGCGCATGAGTCGTGAAGAAATCGAAAAACGTAAAGCACAGCAAACCGAATATGATGAGATTATATTTGACTTCTTTAAGAAACTGCCATGCCACATATGCAATCTGTTGGTGCCGAGTTTTGGAGATATGCGACGCCATCTACGCTTGTCCCACAATATTGAAAGTGGGTTTATATCTTGCTGTGGTCGCAAATTCCATATACGTAAAGGTCTGGCTGAGCATGTGCTGGTCCACAAGAATCCTGAGCACTTTATGTGCGCCCAATGCGGTCGGGTTTTCCAGGACTCAAAAACCCTTGAGACGCACGAGCAAACGCACGTTAATCCTCAGACAGATACGAAGACAGATAAGCCCACTTTCCAATGTGAAAAGTGTCCCAAGTCTTTCACCACAAAAGCTGCTTTCGAGTATCACAATGTATCCAAGCATGTACCCAAGTCAGACTTTCAGTACACCTGTCCCGAGTGCAACAAGAAGATGCCTACGGCTCGTAAATTAAAACAGCATTTGCGCTATATGCACGATCCGGAGAGTGCCATAATCTGCGATAAGTGTGGCAAAACGTTGCGCACTCAGGCGAATCTGAAGAAACACCACGAACTGGAACATTCCGATGCGCCACGTCCCAAACCAGACCCCGTGCAATGCGAGATATGCGGTACATGGCTACGCCATATGTCCGGCCTCAAGCAGCACATGAGCACCGTTCACGAGCCACCCGGAACCGAGCATCGTTGTCCCATCTGCGACAAGAAATCCACGAATGCGCGAGCACTTAAACGACACATTTACCATAACCATCAATGCGAAAGAAAGTTCCGCTGTACCATGTGTGAGAAAGCCTTTAAGAGGCCACAGGATTTAAGAGAGCACACATCTACGCATACGGGCGAAGTGTTGTACACCTGTCCCAACTGTCCGCAGACATTCTTTTCCAATGCCAACATGTACAAGCATCGGCAGCGATTGCATCGCGCTGAATGGGAGGCGGATCGCAAGAAACCGCTGCCGCCCAACATAATGAAGCAAGCCTCGTCGGCAATAAAGAAACGACAAGCCATCGGCCTTGGACTATTTACACAAACCGCTGAGCCTGCTGCGGATGCCCACAAACAGGAGCCTCAACTGCAATAG
Protein Sequence: MAACVLCFGCCKVGESYKIFSEAGLRLNICKTINKHFWLELSSAGGEREEICHQCWECVSSFNIFYQRVYNVHQERREIKNVPIEFCVDTEAANPLAFGAELDALAEDFFASDNVKVEVNELEPLPKLEMLEEPVLEETKATKRACAEYPEIAKRRIKKEQIVATSDSDGDRPLSEFLDLKNNRKPSALRDRQLRRSSRRGCRAKTLPESPSRNLKKEYVSDEELDNDNDTDFVTPEAVLGTDDSESSSESSDTDSGDSLPDVEPEERYAEIPKRVVVKPKKYRKRPKPLVPPVRMSREEIEKRKAQQTEYDEIIFDFFKKLPCHICNLLVPSFGDMRRHLRLSHNIESGFISCCGRKFHIRKGLAEHVLVHKNPEHFMCAQCGRVFQDSKTLETHEQTHVNPQTDTKTDKPTFQCEKCPKSFTTKAAFEYHNVSKHVPKSDFQYTCPECNKKMPTARKLKQHLRYMHDPESAIICDKCGKTLRTQANLKKHHELEHSDAPRPKPDPVQCEICGTWLRHMSGLKQHMSTVHEPPGTEHRCPICDKKSTNARALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMKQASSAIKKRQAIGLGLFTQTAEPAADAHKQEPQLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610837;
90% Identity: iTF_00537697;
80% Identity: -