Dfun007480.1
Basic Information
- Insect
- Drosophila funebris
- Gene Symbol
- -
- Assembly
- GCA_018901825.1
- Location
- JAEIFK010000122.1:1698613-1701183[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.081 5.5 7.6 4.0 1 23 280 302 280 302 0.97 2 11 1.3e-05 0.00089 19.5 0.5 1 23 308 330 308 330 0.99 3 11 0.00018 0.012 15.9 2.9 1 23 336 359 336 359 0.97 4 11 0.35 24 5.6 3.8 1 20 365 384 365 387 0.95 5 11 0.0086 0.58 10.6 1.7 1 23 393 415 393 415 0.97 6 11 4e-05 0.0027 18.0 1.2 1 23 421 443 421 443 0.98 7 11 0.0001 0.0068 16.7 1.2 1 23 451 474 451 474 0.96 8 11 0.0029 0.2 12.1 0.4 2 23 481 502 480 502 0.96 9 11 0.0012 0.082 13.3 1.2 1 23 508 530 508 530 0.98 10 11 4.5e-05 0.0031 17.8 1.2 1 23 536 559 536 559 0.95 11 11 5.2e-06 0.00035 20.8 2.8 1 23 573 595 573 595 0.97
Sequence Information
- Coding Sequence
- ATGCCAAATCGCACGCGCGACTCAGATTCAGAAGATTTGCAATCCTTCCTAATGAATTTTCACAAGGAAATTGAGGATGGCGGCACCGAAGCCAAGGAAAATGGAAACGACGTGGATGTTGATGGGGAAAAACAAGAGGACGAGGAAGACGATGATGATAAATACTTTATTGACGACGAAGGTAACTGCTATATCAAAACAACGCCAAAAAAGCAGCACAAGCTTAAAAGTAAACAAAAACCACCGATAAGCTCAACACCAGCACCAATAACTGTACGCAGCGCAACCAGAGCTAGCAGCACAACAGCTGCGAAAGCTATTAATCTGCGACCAGCCAAGTCCAAATTGGAATCGACGCCCAAATCGGAACCCTCGCCCAAGGCAGTTAATATTCGTCCAGCCGCCCAAAAAAGAATGCAGAATAAAGCGATTCCAACAGCAGTTAATACTCCCAAGGCTTATTTACGTTCAGGGAACTTGCGATCCCAGACAAAGGCCCTAAGAACGGAATCAAAGCCGTTAGTGATATCCAATGAGGTGGAAATAGAGAATGTGGAGGAGGTATTCGAGGAGCTTGTGGATGATCCAAGTACCGTTGAGAATGAGACAATTGCTTCCACCAAAGAATCGGAATTATCTGTCGATGTAAATGAAACTAATGATTCTATTACAATTGACGAGTCAGTCTTGGTGAAGGGCAACATAAGCGACGATGAAGTCTTCGAGTTTGATGATAATTCGGCTAATATATCTGCAAAGCCGGACGTGGACTTTGTGGTATCCGGCAAAGAGTACAAGCTAAAGCCATTGCCGACCCAGTCAGCTGAGTCGCATAAATTCGCCTGCTCCCATTGCAGCTATACGACCAACAAGAAATTCCTAATCTCACGGCATGTGCGCTCTCATGACGCTGAGCTATCATTCAAGTGTTCGATCTGTGAGCGCGGCTTTAAGTCCAACATGGGGCTAGTGAATCATCTGAACACGCACATGGGAAACAAGCCGCATAAATGCAAGCAATGCGAGAGCGCATTCACAACCAGTGGAGAACTTATACGCCATACACGCTATAAGCACACCAAGGAGAAACCGCACAAATGCACCGAATGTAGCTATGCCAGTGTCGAGTTGACCAAGCTGCGACGCCACATGACGTGCCACACTGGTGAGCGGCCGTACCAGTGTCCGCACTGCACGTATGCCTCTCAAGATATGTTTAAACTGAAGCGTCACCTGGTTATACACACGGGTGAAAAGAAATACCAATGTGACATTTGCAAGTCGCGATTTACGCAATCGAACTCGCTCAAGGCACACAAGCTAATCCACAGCGTGGTTGACAAGCCAGTCTTTCAATGCAATCTGTGTCCCACCACATGCGGCCGCAAAGCGGATCTACGTACCCACATGGCTAACATGCACACCTCGGATAAGCCCTTGATTTGTAAGCGTTGCGGCCAAGAGCTGCCCGATCGCTATCAGTATAAGTTGCATATTAAATCGCACGAAGGCGAGAAATGCTATCGTTGCAACCTTTGCAGTTATGCGTCGGTGTCTCAACGGCATCTGGACTCTCATATGCTTATTCACACCGACACCAAGCCCTTCAGGTGCGATCTGTGTCCACAGGCATTCCGGCAGCGTCAATTGCTGCGTCGCCATAAAAATCTAATGCACAATGAAGACTATAAGCCACCGGAGCCGCGTGAAAAGCTACACTCATGTCCCAGCTGTGCGCGTGTCTTTACCCATAAGGGTAACCTAATGCGGCACATGGAGACCCACGATGATACACTCAATGCGCGTGAGGAGAAGCTTAAACTGAAATTGGGACGCAACGTGCGACTGCAGCCAGATGGCAGCATTGTGACGTTAGTGAATGGAACTGACATTGATGTGCTAGGAAAGAACTCGGATATATCGATTGACTTGGAAGATCAGTATGAGATCACTGAGCTGGAGCAATTAGAGGATGACGAGGAAGATGAGGAGCACAGTGAAACTATAGTGGAAACGATACCCAGTTCCACGTCCAGAACGAGAAACGGAACCAATACTGTCGTAATCAGAGAGCGTCAGCAGAGGACACCAAGTAAACCCATCATTATTAATCGCCAATTGAAAGTACCTCGCGTGCATCGCGAGGTTACAACTCAAGGTGGCACATTTCGCATTAAGGAGGAGCCGGACGCCAATGAATTTACCGTGGAGTTGCAGGGTGACGATGATCAGTTCATGGTCGTTCAACTGGTTAACGATGATAATGAAGTTGTGGTGAAACGTGAGCCAAGCACGCAAAAAATCAATGCCAACAATTGTTTTGGCTTCGAGGATGATGCCGAAGCTGAATACGATGAGTATGTTGAGCCCGTGGCCGAGGTGGATGCCACATCACAGGAGTTTCTGCAGCTTATGGATATGATTGAACAGGATACGTAG
- Protein Sequence
- MPNRTRDSDSEDLQSFLMNFHKEIEDGGTEAKENGNDVDVDGEKQEDEEDDDDKYFIDDEGNCYIKTTPKKQHKLKSKQKPPISSTPAPITVRSATRASSTTAAKAINLRPAKSKLESTPKSEPSPKAVNIRPAAQKRMQNKAIPTAVNTPKAYLRSGNLRSQTKALRTESKPLVISNEVEIENVEEVFEELVDDPSTVENETIASTKESELSVDVNETNDSITIDESVLVKGNISDDEVFEFDDNSANISAKPDVDFVVSGKEYKLKPLPTQSAESHKFACSHCSYTTNKKFLISRHVRSHDAELSFKCSICERGFKSNMGLVNHLNTHMGNKPHKCKQCESAFTTSGELIRHTRYKHTKEKPHKCTECSYASVELTKLRRHMTCHTGERPYQCPHCTYASQDMFKLKRHLVIHTGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCNLCPTTCGRKADLRTHMANMHTSDKPLICKRCGQELPDRYQYKLHIKSHEGEKCYRCNLCSYASVSQRHLDSHMLIHTDTKPFRCDLCPQAFRQRQLLRRHKNLMHNEDYKPPEPREKLHSCPSCARVFTHKGNLMRHMETHDDTLNAREEKLKLKLGRNVRLQPDGSIVTLVNGTDIDVLGKNSDISIDLEDQYEITELEQLEDDEEDEEHSETIVETIPSSTSRTRNGTNTVVIRERQQRTPSKPIIINRQLKVPRVHREVTTQGGTFRIKEEPDANEFTVELQGDDDQFMVVQLVNDDNEVVVKREPSTQKINANNCFGFEDDAEAEYDEYVEPVAEVDATSQEFLQLMDMIEQDT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00569154;
- 90% Identity
- iTF_00537685;
- 80% Identity
- -