Basic Information

Insect: Drosophila funebris
Gene Symbol: -
Assembly: GCA_018901825.1
Location: JAEIFK010000678.1:19319256-19323863[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0019 0.13 12.7 2.9 1 23 214 236 214 236 0.96

2 26 0.091 6.2 7.4 1.3 1 23 242 264 242 264 0.97

3 26 0.26 18 6.0 0.5 2 23 296 317 295 317 0.95

4 26 0.016 1.1 9.8 1.6 1 23 392 415 392 415 0.93

5 26 0.61 41 4.8 2.3 2 22 427 447 426 447 0.96

6 26 8 5.4e+02 1.3 4.5 1 23 456 478 456 478 0.96

7 26 0.012 0.85 10.1 2.8 2 23 497 518 496 518 0.97

8 26 0.0063 0.43 11.1 0.3 1 23 595 618 595 618 0.94

9 26 0.00022 0.015 15.7 0.3 1 22 627 648 627 648 0.95

10 26 0.26 18 6.0 5.9 1 23 657 679 657 680 0.95

11 26 5.2e-05 0.0035 17.6 0.3 2 23 704 725 703 725 0.97

12 26 5.3e-06 0.00036 20.7 3.5 1 23 733 755 733 755 0.99

13 26 0.033 2.3 8.8 3.0 1 23 904 926 904 927 0.95

14 26 0.0075 0.51 10.8 0.7 3 22 936 955 935 955 0.96

15 26 0.082 5.6 7.5 0.5 1 23 964 987 964 987 0.91

16 26 1e-05 0.00068 19.9 1.9 1 23 1012 1034 1012 1034 0.97

17 26 0.00013 0.0087 16.4 0.9 1 23 1041 1063 1041 1063 0.98

18 26 0.0067 0.45 11.0 0.0 2 21 1090 1109 1089 1110 0.93

19 26 0.012 0.79 10.2 3.9 1 23 1155 1178 1155 1178 0.96

20 26 0.018 1.2 9.6 0.4 1 23 1215 1238 1215 1238 0.96

21 26 0.0009 0.061 13.7 3.5 1 23 1263 1286 1263 1286 0.97

22 26 1.3e-05 0.00086 19.5 0.1 2 23 1310 1331 1309 1331 0.95

23 26 4.3e-05 0.0029 17.9 2.9 1 23 1337 1359 1337 1359 0.99

24 26 4.7e-06 0.00032 20.9 1.9 1 23 1365 1387 1365 1387 0.97

25 26 5.4e-08 3.6e-06 27.0 2.4 1 23 1393 1415 1393 1415 0.99

26 26 0.033 2.3 8.8 0.2 1 21 1421 1441 1421 1445 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0019	0.13	12.7	2.9	1	23	214	236	214	236	0.96
2	26	0.091	6.2	7.4	1.3	1	23	242	264	242	264	0.97
3	26	0.26	18	6.0	0.5	2	23	296	317	295	317	0.95
4	26	0.016	1.1	9.8	1.6	1	23	392	415	392	415	0.93
5	26	0.61	41	4.8	2.3	2	22	427	447	426	447	0.96
6	26	8	5.4e+02	1.3	4.5	1	23	456	478	456	478	0.96
7	26	0.012	0.85	10.1	2.8	2	23	497	518	496	518	0.97
8	26	0.0063	0.43	11.1	0.3	1	23	595	618	595	618	0.94
9	26	0.00022	0.015	15.7	0.3	1	22	627	648	627	648	0.95
10	26	0.26	18	6.0	5.9	1	23	657	679	657	680	0.95
11	26	5.2e-05	0.0035	17.6	0.3	2	23	704	725	703	725	0.97
12	26	5.3e-06	0.00036	20.7	3.5	1	23	733	755	733	755	0.99
13	26	0.033	2.3	8.8	3.0	1	23	904	926	904	927	0.95
14	26	0.0075	0.51	10.8	0.7	3	22	936	955	935	955	0.96
15	26	0.082	5.6	7.5	0.5	1	23	964	987	964	987	0.91
16	26	1e-05	0.00068	19.9	1.9	1	23	1012	1034	1012	1034	0.97
17	26	0.00013	0.0087	16.4	0.9	1	23	1041	1063	1041	1063	0.98
18	26	0.0067	0.45	11.0	0.0	2	21	1090	1109	1089	1110	0.93
19	26	0.012	0.79	10.2	3.9	1	23	1155	1178	1155	1178	0.96
20	26	0.018	1.2	9.6	0.4	1	23	1215	1238	1215	1238	0.96
21	26	0.0009	0.061	13.7	3.5	1	23	1263	1286	1263	1286	0.97
22	26	1.3e-05	0.00086	19.5	0.1	2	23	1310	1331	1309	1331	0.95
23	26	4.3e-05	0.0029	17.9	2.9	1	23	1337	1359	1337	1359	0.99
24	26	4.7e-06	0.00032	20.9	1.9	1	23	1365	1387	1365	1387	0.97
25	26	5.4e-08	3.6e-06	27.0	2.4	1	23	1393	1415	1393	1415	0.99
26	26	0.033	2.3	8.8	0.2	1	21	1421	1441	1421	1445	0.91

Sequence Information

Coding Sequence: ATGTTGCCGACACATATCTGCCGCACCTGTGCCGTACATGATGTGCATTTATTGGCGCTCTCCACGCGCATCGAGAAATATCCAAACAAAAGTTTATGTGACATTTTGCATGAGCTAACACAAAACGATCCCTTAATGGAACACTCCGATGATAATCTGCCTCAGTATTTGTGTGTCGACTGCTTGCGTAAGCTGGAAGATGCTTATGCATTTGTATTGCAAGCACGACAGGTACAAGAGCAACTGTTGCACAAAATACGCAAAGGATTGCAGTGTCTGGATGAGACACCTATAGATATAGCCCCGCAGCACATAAAGACAGAAACAGAAATTTCCTTGGAGCAAACCAACAGTGAAGCACCATTGGATGTCAACGATCTTGAGGTAGCAACTATGTCTGTTGCTGCTTTAAAAATGCAACCGGAGTGTGAGACCGACAGTAGCCATTCAGACGTGGCTGATGATGGTGTGCTAGACCTTAAGTCCATGCAGCTGAGGCGAAGCACACGCAAAGCGAAACTTGTCACAGACAGCGAAAATGAAGCGACATCGGAAAATGCAAACATATTGCCCCTCAAGCGTCGTCGCGGTCGGCCTGCACGTAATTTGAAAAAGGAAACTATCAACAATGAAGGACGCCATGCTTGCAAGGTGTGTGGCAAGACGTTTTCGTGGCATCGGGACATGCAACGCCATGCTCGCGTACACTTCGAACAAGCAGGCTACGTGTGTGAGAGCTGTGGCAAGGGATTCCTTCGCAAAGACAAGTACATGTTCCATTTGCGATCGCACGAGAAGCGTGAAGCTAAACGAGCGGCTCTGCAGGTGGGCAATGAGTGGCGCTTTGCGGAGCGCCTCTACAGTTCGGGACGTCTGAAGCGAATCGAGTGTATGTTGTGCGGCTTGAAGTGCCAGCGGATTCAGGAACTTCGTGAGCATCTGGCTAGTCACGTTAGCATTGAAACCTTGTCGAGTCTCAGTGACAATAGCGATGTTATTAAGGAACAGTTTAATAACAATCAATTGGACTTGATGCAAATTAAGCAACAGGTGTGTGCGGACATAGCCAAAGGACGCCAATATCTAGATAAATACTGTCTTGTAGTAAATGCGCATGGCTATGAGCTCTGCCTGAGCGACTCGGACGAAGAGTTGGCTGGAATGCCCCCTCCATACCAATGCCTACCTTGCAACACTTTCTTCTCACGTAAATATCGTCTGATGCGGCACACGCTGGAGGAGCATACTCAATCGAAAACTGAGACAACTCCTTGGCAGCGTTGCAACCATTGCCAAATTGGATTTGTGTGTTTAAAGCTGCTAGAGCAGCATCAGCGCACACAATGCAATAATTTGCTAAAACGTTACAGTTGCCCCAACTGTCCAGGAAAATTTATGTGGTTGCACACTTTGAAGCATCATGCTTGCTCCCATCGCATGAGATTTCCAGGGGAGGAGGATCGAGAGAAATGCCAAAGCCGTCAGATTCAGTGTTGTCTTTGCGATAAGCATCTGCAAAGAATGTCAGAGCTACGTGCTCATTTAATCACACATTGCGATGGACGAAACGAGGTTGAACCGGATCAAGGGGCTACTTTCTTTCGTTGTTACTACCCGGATGGTTTGACCTATACCCAAACGGAGCTCAGCACACGAATTGCCAACGACTTTGAGGGACAGGATTATGGTCGCTACTTCAATGCCTGCACTGGCAGCGGCCAAGAGCTGGATTTCTTTGACTCTGATACAGATTTAAGCGATCAGTCAGCCTCAGCATTCGTACATTCGTGTGGCTTGTGTGGCGTGAGTACAATTCGCCTTGCCCAACTCCTGAAGCATCAACAAGATGACCATAGCGAGATGAAGGTCCCATTGCCTCATGTCTGTGATAAGTGTGGGTTGGGATTCGTTTCTGAATCGTTGCTTCAGCAGCATCGCCGACGTATATGCGCCAAGCGACATGCAAAGTACCATTGCCAGCGTTGCAATCTTCACTTTATCTGGCAGTCAAACTTTGAGAGACACTTGGAAATACATCATGAAGGGGAAACAGAGGAGCATGAGCCCATTATCAGGCTACGAAGCAAACGCCAACAACCTGACAAACTACAGTGCAATGAGTGTGATAAGGTCTTCATCTGGCCAAAGGATCTGACGCGTCACAAGCGCATTCACCAGCCGCAGGCATCGGCACAATACGAATGCAGCTACTGTGAGCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCGCATATGCGTGTGCATGGCGAACAGCAGTTGGGTGTAACGATTATGCCTAGCAGGGAACCGGATCCATCGATCTTACAGCGGATACCAATGTTGAAGCAAATGTGTCAACCAAATGGATGCAAGCAGATTCAGTGCATGATCTGTCTCTCTCAGCACACGAAGATCTCTGATCTGCGCACGCATTTGGTGAAGCATCAGTACGTTGTGGAGTTTGCGGAAGAACGGGCCACGCCGGAGAGCATTGCGAATATTTGTCGTGCCCTATATCCGGAACAGGGGTCTCCGCTGGATAAGCTACAGTTGATCGAACGCATTCAGAGCGATGTGGGGAAGGGGACGGAATTGGAAAGATTCATTTCGATAACGAACGAGGCGGGTATTGAGCTTAGTCTGGACAGCAGCGAAACTGATACGGATTCGGACTCAGCCGAAGTTGGAATGAGCAGCAGGGGAAAACAATACAATTGTGATCTGTGCCAGTTGAAGTTGCCGCGTAAACATCAACTCTATGCCCACCAGCTGGAGCATCATACATGGCAACAGGCAACCCGCATTTGTAGCCACTGTCAGGCCAGATTCATCAGTGAGGAGTTGCTGGAGCATCACTATCGTACGCTATGTCGCAATGCTCAGAAGCGTTTTCTCTGTCGGAAATGTCCATTACGCTTTCGCTGGCGGGATAATCTGAAGCTGCACACGGATGTGGCGCATCAGGAAGCAACTGGAGAACAAACGAGCCTAAGTATCCAATTGAATGGACAAAGTCTCCTGCCTGTTGTTAGCTACGATTGTACTGAGTGTAATCGCAGCTTCAAAATGCAAAAAGATCTCACTCGACACACGCTGATGCATGCCCAGGAATCGAGCATATATCGGTGTCGTTGGTGTGCCCGTCGCTTCTATCGCCAGGCTAATCTTCTGCAGCACATAGAGCGTCATGGCATCAGTGCCGCACAGCTGCCTTATGCAGAGTCCCTGCTTAATGCCAGTCGTCACCCTAATGGCCAGAAGTCCATCCAATGCAAGGTGTGTGATATACGTTTCCCCACAATTGCTGCATTGCGTTCCCATTTGTCGTCCACGCCGAGCGGAACTCATCATGAGATTGAATCGATGCTCAACTATTCGATTACCAATCAGTTGGGCTACGAACTGCACTTAGACGACTCGGAAACGGATGAGGAGGACAAGCCACCTGGCATACCGACACACTATACCTGTGGTATGTGTCAGCTCCGTTGTGTACGCAAATATGAGCTGCATCAGCATCAACAGGCGATGCATAGGCTAGAACGGATTACCGATGGGTGTGATCAGTGCATTTATAAGAGTGTATCTCCGGACCTTATCGCCTATCATCAGCGTGTGCAGTGTGGAAACACGGAGAAACAATTTAAATGCGTCAACTGTGGCTATAAGTTTATGTGGGAGTCGAATCTGCTGCTGCACATTCAATTGCAGCATCCTAGCAATGATGAACAGGAGGAGACGCCATCGGTGCCTGCACCAGAGACAACAACTACAGAGTGCCAGATCTTTCAGTGCGGTCAGTGCCCGCGTAAATATAATCGAAAGGATCGACTGACGGCTCATGTAAAGAAGTGTCATGCACCAGGTGCAGCGGGTCCAATAAAAACCAATTCGGCTTCAACTGTTCCCAAACAACAGAAGAGTTTCCTCTGCGCATTTTGCGGCAAGGCGGTGAGCTCCTCCTCCAATCTCATTATACACATACGTCGACATACCGGCGAGAAGCCCTTCAAGTGCGACTATTGCGACATGGCTTTTCCCCGCTCTTCTGATTTGCAGTGCCACCGACGTACTCACACTGGCGAACGGCCGCATGTGTGCACCGTGTGTCAAAGAGGATTCGCCCGTTCCTACAAGTTGCAGCAACATATGCGAATCCACAATGGGGAAAAACCCTACAAGTGTACCTATTGCGACAAAAGCTTCACTCAGTCCAATGACTTAACGCTCCACATACGACGTCACACGGGCGAACGTCCCTATCAATGTGAAACCTGCGGGGATCGTTTCATTCAGGGCACGGCACTCAAGAATCATCGACTACAGAATGGCCATTACGAGGCAGTGGATGGCCTGGCTAAAAATAATTAA
Protein Sequence: MLPTHICRTCAVHDVHLLALSTRIEKYPNKSLCDILHELTQNDPLMEHSDDNLPQYLCVDCLRKLEDAYAFVLQARQVQEQLLHKIRKGLQCLDETPIDIAPQHIKTETEISLEQTNSEAPLDVNDLEVATMSVAALKMQPECETDSSHSDVADDGVLDLKSMQLRRSTRKAKLVTDSENEATSENANILPLKRRRGRPARNLKKETINNEGRHACKVCGKTFSWHRDMQRHARVHFEQAGYVCESCGKGFLRKDKYMFHLRSHEKREAKRAALQVGNEWRFAERLYSSGRLKRIECMLCGLKCQRIQELREHLASHVSIETLSSLSDNSDVIKEQFNNNQLDLMQIKQQVCADIAKGRQYLDKYCLVVNAHGYELCLSDSDEELAGMPPPYQCLPCNTFFSRKYRLMRHTLEEHTQSKTETTPWQRCNHCQIGFVCLKLLEQHQRTQCNNLLKRYSCPNCPGKFMWLHTLKHHACSHRMRFPGEEDREKCQSRQIQCCLCDKHLQRMSELRAHLITHCDGRNEVEPDQGATFFRCYYPDGLTYTQTELSTRIANDFEGQDYGRYFNACTGSGQELDFFDSDTDLSDQSASAFVHSCGLCGVSTIRLAQLLKHQQDDHSEMKVPLPHVCDKCGLGFVSESLLQQHRRRICAKRHAKYHCQRCNLHFIWQSNFERHLEIHHEGETEEHEPIIRLRSKRQQPDKLQCNECDKVFIWPKDLTRHKRIHQPQASAQYECSYCERKFHRKDGLKSHMRVHGEQQLGVTIMPSREPDPSILQRIPMLKQMCQPNGCKQIQCMICLSQHTKISDLRTHLVKHQYVVEFAEERATPESIANICRALYPEQGSPLDKLQLIERIQSDVGKGTELERFISITNEAGIELSLDSSETDTDSDSAEVGMSSRGKQYNCDLCQLKLPRKHQLYAHQLEHHTWQQATRICSHCQARFISEELLEHHYRTLCRNAQKRFLCRKCPLRFRWRDNLKLHTDVAHQEATGEQTSLSIQLNGQSLLPVVSYDCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISAAQLPYAESLLNASRHPNGQKSIQCKVCDIRFPTIAALRSHLSSTPSGTHHEIESMLNYSITNQLGYELHLDDSETDEEDKPPGIPTHYTCGMCQLRCVRKYELHQHQQAMHRLERITDGCDQCIYKSVSPDLIAYHQRVQCGNTEKQFKCVNCGYKFMWESNLLLHIQLQHPSNDEQEETPSVPAPETTTTECQIFQCGQCPRKYNRKDRLTAHVKKCHAPGAAGPIKTNSASTVPKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQRGFARSYKLQQHMRIHNGEKPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCETCGDRFIQGTALKNHRLQNGHYEAVDGLAKNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558059;
90% Identity: -
80% Identity: -