Basic Information

Insect: Drosophila fulvimacula
Gene Symbol: L_1
Assembly: GCA_035045555.1
Location: JAWNOX010000180.1:8350225-8356794[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1e-05 0.00069 20.0 2.9 1 23 133 155 133 155 0.98

2 17 0.34 24 5.7 6.2 1 23 161 183 161 183 0.97

3 17 1.7e-07 1.1e-05 25.6 3.2 1 23 189 211 189 211 0.99

4 17 1.2e-05 0.00085 19.7 0.4 1 23 217 239 217 239 0.99

5 17 0.014 0.94 10.1 0.2 2 23 318 342 317 342 0.93

6 17 0.0003 0.021 15.3 0.2 2 23 371 393 370 393 0.96

7 17 0.061 4.2 8.1 0.7 1 23 457 479 457 479 0.97

8 17 0.071 4.9 7.8 0.3 2 23 487 508 486 508 0.91

9 17 0.02 1.4 9.6 1.2 3 23 519 541 516 541 0.86

10 17 3.3 2.3e+02 2.6 1.0 2 23 577 599 576 599 0.95

11 17 0.0025 0.17 12.4 1.1 1 23 642 665 642 665 0.97

12 17 0.0063 0.44 11.1 1.6 2 23 840 862 839 862 0.96

13 17 0.11 7.8 7.2 0.1 1 23 868 890 868 890 0.92

14 17 0.54 37 5.1 0.4 2 23 898 919 897 919 0.93

15 17 0.31 21 5.8 1.3 1 23 1015 1037 1015 1037 0.94

16 17 0.023 1.6 9.4 0.0 1 23 1047 1069 1047 1069 0.96

17 17 0.00022 0.015 15.8 1.2 1 23 1074 1096 1074 1096 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1e-05	0.00069	20.0	2.9	1	23	133	155	133	155	0.98
2	17	0.34	24	5.7	6.2	1	23	161	183	161	183	0.97
3	17	1.7e-07	1.1e-05	25.6	3.2	1	23	189	211	189	211	0.99
4	17	1.2e-05	0.00085	19.7	0.4	1	23	217	239	217	239	0.99
5	17	0.014	0.94	10.1	0.2	2	23	318	342	317	342	0.93
6	17	0.0003	0.021	15.3	0.2	2	23	371	393	370	393	0.96
7	17	0.061	4.2	8.1	0.7	1	23	457	479	457	479	0.97
8	17	0.071	4.9	7.8	0.3	2	23	487	508	486	508	0.91
9	17	0.02	1.4	9.6	1.2	3	23	519	541	516	541	0.86
10	17	3.3	2.3e+02	2.6	1.0	2	23	577	599	576	599	0.95
11	17	0.0025	0.17	12.4	1.1	1	23	642	665	642	665	0.97
12	17	0.0063	0.44	11.1	1.6	2	23	840	862	839	862	0.96
13	17	0.11	7.8	7.2	0.1	1	23	868	890	868	890	0.92
14	17	0.54	37	5.1	0.4	2	23	898	919	897	919	0.93
15	17	0.31	21	5.8	1.3	1	23	1015	1037	1015	1037	0.94
16	17	0.023	1.6	9.4	0.0	1	23	1047	1069	1047	1069	0.96
17	17	0.00022	0.015	15.8	1.2	1	23	1074	1096	1074	1096	0.97

Sequence Information

Coding Sequence: ATGTACAGCACGCACACTTCATCGAGCTACTCGCCCAGCATCTCGGATGGCACTTTGACGCCCAAttcacagctgcagcagccgcagcagcagcagcagcagcagcagcatcaggcACAGCCTGGCGAGGAGCCCGGCGAGGAGGCCAAGGCGAATGGCGATGGTGTGCAGCAAacggagctggagcaggagctgaGCAAGCCGAAGCGACCGGCACActtgcatcatcatcatcatcatcattatcatcatcagcagGCGCTGAAAATAGCGAACAAATTGCGCAAAATCAATAAGGATGCAAAACTGGCTGcaggacaaggacaaggacatGGCACAGCCGCCAAGTTTGATAAGTTGACAGGGGAGGGGATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTCCAGAGCCACGCCGAGCATTTGCCTTTCAAGTGCGAATACTGCGCGAAGCTCTTCAAGCACAAACGCTCGCGAGATCGTCACAAGAAGCTGCATACAAATGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCCAGAAGCGATCATTTGAAGATTCACATGAAGACGCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGCGGCTACAACACGGCCGCTGCGCTGACCTCGCacatgcaaaagcacaagaaGAACGCCGCAATCCTGGCGGCTGGCGGCAATCCCAATGCCCTCAACTATAGTCCACGCTCCACGGGCTCCGCCTCGATCTCGAGCAACGGCAGCTTGCATAAGCGTCGCTATGCCCTGGCGCTGGCCTCCGACAGCAGCCCCAGTCGCTTGGAGTTTCCCAAGCGTGCGCGTGGCCAGCTAACGACCACGCCCACGGCCACAACaatagccacgcccacgccgtTGCTGCGCTGCAGCTACTGCCCCAAGGCAACGGAGTTCAGCAGCCTCGAGCAGCTGAACGCGCATCTGCAGAGCAcgcacgagcagcagcagcagtcacagcagcagcagcagcagcagcagcagctgaaggatGCCGATGGCCAGACGAATGGCTTCCAGTTGAGCTGCGAATACTGCACCATGAAATTTGTGAACATCGCGGCGCTGTTCCAGCACATGAGGGTGACGCACCTGGATCGTCTGAGCAGCCCGAATGCGTATTACGAGCACTTCAATCGGCTCGGCTCGCCGCAGTCGAAGCTGAAGTCGGATCTGGCGACGTCGGAGAAGCCGGAGCAGGAGCTGCCCACCGACCTGAGCAGCAACAAGCGACGCCCGCTGGCATCGCCCACGCAGCCGCCGCCGGCTCCGCCGGGCATCTTCTTCTGCAACCAGTGCAACGCGGGTCTGCCGGACTTCGAGAGCTTTCGCAATCATCTGAAGAGCCACATAGCCGAGGGCATGCAGCTGATCTGTCCGCACTGCGGCCTCAGTCTGCCCGAGCAGTGCGAGTACGAGCGCCACGTGGTCGCCCACTTCCTGATCAGCAGCTCCGAGTTCAACTGCTGCAGCGCCAGCTGTGGCAAGTCGTACGCCAAGGCGGAGGAACTGCATCAGCATCTGCTGGCCGAGCACGTCCAGACCATGCTGAAGTGCGTGCTCTGCTCGGAGCTCTGCGAGAATCGCATGGCGATGCAGCTGCACCTGGCCTGCGCCCACAGCCAGGAGTCGAAGCTGCTCAGGTGCAGCGCCTGCCTGGAGCTCTTCCGCAACGACGCCGACTTCCATGTGCATGTGAAGACGCGCCATCAGCTGGGCAACCAGAACGTGAGCAATCCACCAGCTCCCACCAATCCGCTGCAGTGCATGTTCTGTCGCGCCGTCTGCTCCTCGGAGCTGGAGATGCACTTCCATCTGGCGGCGCATGCGCGGCAGTTCCGCTGCCCCAGCTGCCCGGAGACATTCCATGTGGAGTTCCTGCTGGACAGGCATATGCAGAGCCAGCATGGCGGCATCAAGGACAAGGAGTCGCCCGTGCCGGGCAACATGGGCAGCTTGTATGTCAACGCCTTGCTGCCGCCTCTggccgcagccgctgcagccgctgccgccgctaacaatgccaacaacgccaacaacaacaacaacaacaacaacagcaacctgCACATCGACTACAATGTCGCCTTCAAGGGTCTCTTTGGCGGCAGCAATCCGCCGAGCAAGTTCTACAACAGCCCGCTCCAGGTGGACACCAAGCAGAGCCCGCATCCGGCGCTGATGTACGGCCTGAGCCAGCGCTACCTGATGGAGATGTACGCAGCGAAGGCCAATTCCCCGGCCAATGGCAGCGGCGTCGCCGAGCTGCCCACTCCGCAGGCCGTGCAAGCCTCGACAGCggccagtggcagcagcagcagcagcaacagcttcagCTGCGGCATGTGCGAGCGCCAGGATCTGCGCAGCGAGGCCGAGCTGCACTCGCATCGGAAGCTCGCGCACAATCTGAAGACGGGCGTCAGCCTGAGGTGCGCCTATTGCTCCGGCAACTACAAGAGCCGCGCCGAGCTGGAGCAGCACATGAAGAGCTGCCACAACTCGAGCGGCAAGCACAAGTGTCTCATCTGCGATGAGATCTTCCCCTCGCCGGCCATCCTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGCCAGTCCGGCAAGTGTGCCCACTGcggccagcagctggagcacgTGGCCGCCTTCCGTGCCCACCTGGGCGAGCATGGCAACGACGGCAATCTGCCCATGGCCTGCATCTGCTGCCGGCAAACACTCCACTCGGAGTTCGAGCTGAGTCTGCACGCCAAATTCCACACCAAGTCGCCCGGCTGCAACAGCCTGCAGGAGCCCGTCTGCGCGCTGTGCCTGGAGCCGCTGCCCGGCGCCGGAGACACCGCCAAGCTGTGCGAGAAGTGCTGCCGCAAGCACAATCTGAATGGCAAGCGCAAGGAGCAAGTGCAGCCAGCGGCCATAGCCGCTCCAGCTGCCGCAGCGCTGGCCTACCTCGAGCATCGCTGTAATCTGTGCAAAATGATCTTGCCCCACGCCCAGAAGCTGCAGGAGCATCTCGTCGAGCACACCTTTGCGGGCACCGAGCAGCGCGGCTACAATTGCTACATCTGCTCGGCGGTGTTCACGGCTCCGGGTGGCCTGCTCACGCACATCGCGGAGCACGGCACGCGTCCCTATGACTGCAATTTGTGCCCGGAGAAATTCTACTTCCGCGCCGAGCTGGAGCATCATCAGCGGGCGCACGAGCTACGCCCACAGCCGGCAGCTGTGGCACGTCCCAAGCAGGAGACGCACAGCTCCACAGCCAGCTCGCCCCTAACGCTCAGTCCCAGCCACGTCAAGCAGGAGCTATACGAATCGGAGCCAGCCAATTCGCCCAACGCCACGGAGCTGCCCGTGCAGCCGGACGAAGAGGAATACATCGAGGTGGAGCAAGTGCCGCAGGAGACGCTGCGATCTGGTGAACTCCTAAGCACCGAGCgttccagcagcagcgcctaa
Protein Sequence: MYSTHTSSSYSPSISDGTLTPNSQLQQPQQQQQQQQHQAQPGEEPGEEAKANGDGVQQTELEQELSKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGQGQGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGQLTTTPTATTIATPTPLLRCSYCPKATEFSSLEQLNAHLQSTHEQQQQSQQQQQQQQQLKDADGQTNGFQLSCEYCTMKFVNIAALFQHMRVTHLDRLSSPNAYYEHFNRLGSPQSKLKSDLATSEKPEQELPTDLSSNKRRPLASPTQPPPAPPGIFFCNQCNAGLPDFESFRNHLKSHIAEGMQLICPHCGLSLPEQCEYERHVVAHFLISSSEFNCCSASCGKSYAKAEELHQHLLAEHVQTMLKCVLCSELCENRMAMQLHLACAHSQESKLLRCSACLELFRNDADFHVHVKTRHQLGNQNVSNPPAPTNPLQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGIKDKESPVPGNMGSLYVNALLPPLAAAAAAAAAANNANNANNNNNNNNSNLHIDYNVAFKGLFGGSNPPSKFYNSPLQVDTKQSPHPALMYGLSQRYLMEMYAAKANSPANGSGVAELPTPQAVQASTAASGSSSSSNSFSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPGCNSLQEPVCALCLEPLPGAGDTAKLCEKCCRKHNLNGKRKEQVQPAAIAAPAAAALAYLEHRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGYNCYICSAVFTAPGGLLTHIAEHGTRPYDCNLCPEKFYFRAELEHHQRAHELRPQPAAVARPKQETHSSTASSPLTLSPSHVKQELYESEPANSPNATELPVQPDEEEYIEVEQVPQETLRSGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00545474;
90% Identity: iTF_00502755;
80% Identity: -