Dful011044.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila fulvimacula
Gene Symbol
-
Assembly
GCA_035045555.1
Location
JAWNOX010000192.1:1941668-1944936[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 6 0.32 22 5.8 0.1 2 23 327 349 326 349 0.89
2 6 0.00063 0.044 14.3 0.9 1 23 360 383 360 383 0.92
3 6 0.00028 0.019 15.4 2.7 1 23 393 415 393 415 0.97
4 6 3.2e-06 0.00022 21.5 2.1 1 23 705 727 705 727 0.97
5 6 4e-06 0.00027 21.2 0.2 1 23 733 755 733 755 0.98
6 6 1.8e-05 0.0012 19.2 4.2 1 23 761 783 761 783 0.98

Sequence Information

Coding Sequence
ATGAGCGCCATGGCCGCCAGCCGTTGCCCCACGCCGTTTGCGTTTCCCTTCTCGCCGCTCGGGCTGAGCCTGTTCGACATTGATCCGTCCAGAATACTGAACCTGCTGCACCACCAGACCTGGCTGGCCGAGGAGGCATTGCGGACTCGCGGCCTGCTCAGCGCGCCAAAGGACTTTCCCCACCGTTTTACCACGCTAAGCGATCTGCTTACCAAGGACTATCAGCCAACTGCGGCCAGCTATGCGGCCAAGCAGACGCAGTCCACCACGAGCCGTTCCAGCGATCCACagtacaaacaacaacaacaacagcaaccgtctcaacaacaacaacaacaacaacaagcacagcCTCATGGCGCCTTCAATATGCgctatgccacgcccactggcttCTTTCAGCCCTCGAAAGGCGGCAAGTCGGCCGGCACGCCCTCGCCCCAGCAAATGGCCACCTCATCGACGGCCATCTCAGCGGAATCGCAGCTGGAAGGTCAGTCAGAGGGCAACGATGACGTCACCATTGTCGAGCTGGGCAGCGAGCGCAGCGTCGTAACGCCCAATAGCAGTGCTCTGCTCTACAAGGAGtcgctggagcagctgctggcccagcagcaacagcaccagcagcagcgacgtcgcaatgccaacaacagcacGCCCAGCACAGGAAgcgttggagctggagctggcagtggagctggtgctggcgctggagctggagctggagctggtgtCATTGTGGACGCCAGTGGCTTGCGCCAATAtacacagctgctgctgtccggCGGCGGCACGCCCGTCAGCTGCACGGACACCTCGAGCAGCTGCAAGGAGAAGAGCTCCTCGTCGTCTACCTCATCGACGCCGCCGCCAAGCGGCGCGCTGCTcgcccagcaccagcagctgagCCAAATGCTGAAGAGTCCCTCGGACACGTGCTCCTCGCTGTTCAGCGAGCCCATTGAGGAGGAGACGCGCTGCGTTGTCTGCAATGCCCACTTCCCGAACGTCTGGCTGCTCGAGCAGCATGCGGCCCTGCAGCATCCGCACATCGGGCCGGGCGAGGAGAAGCCCTTCATATGCGAACAGTGCGGCCAGTCGTATCGCTATCGCAGCGCTTATGCCAAGCACAAGGAGCAGAATCATCGCGCCCGCCTGCCCGCGGACAAGCTCTTCACCTGCGACGTCTGCGGCATGCAGTTCCGCTATCTGAAGAGCTTCAAGAAGCATCGGCTCAACCATGCCCTCGAGCGCCTCCATGGCAAGAAGTCCATTGGCGTGGGCgtcggcgtgggcgtggcacgcaTGATTAGCGgcacagcggcagcgacggcagcagccgcagcagcagcagccgcaacatcAGCCCAGCTGGACCAGGATGTGGTCACTAGCTCCCAGGAGCCGATGCTGGCCGACGAGGGCGAGGATCTGCGCATCAATGTGAAGCGCGAGGGCGACGACCCCGCCCACCAGCAGGAGGCCACCAGCGATGAGCACGAACAGGACAACACCATCGACTCGGCGGGCATCACGATGCtctacaacgacaacaactcaTCGGCTTCGGCCTCCACGAGCGCCACGGAGCCGAACATCAGCAGCTCGGACGGCATACATAGTACAAACAAGCGGTCACGCCTGTTGAACAGCGGACACCACTTGGAAACGGATCCCTCctatcatcatcagcaacaccatcatcaccatcaacaacaacaacagcaacagcagcagcagcaacaacagcaacatcatcatcatcaacagcagtcgcagtcgcagtcacagcAACTACCGCCGCATCTGGCGCACGTCTCACTGCCAATGGCCAGCGCTGCAGCTGGGTCCTCGTCGGCAGCCGCCGCTGCGGCGGCCGCTGCAGCTGGGTGCAATTCCAGTCCCGGAGCTGGGGCAGCTGGCGCCGCCAACAGCGTTGTGGGCGGCAGCGGCATTAGCTCGCTCAGCTCGCTGACTTCGTTGATCAATGCGGAGCGCATACCCAATGAGCAGTTCCTGGGTCTCAATCCGCAGGAGGCTTCAATACTCAACTTTTTGCGAGTCGATGCCGCCGAGCGACAGCGCGACAAGCGACCCACCACATCGCGCTTCGCCTGCCCCTTCTGTGGCAAGTGCGTCCGCTCCAAGGAGAACCTGAAGCTGCACGTGCGCAAGCATACTGGCGAACGTCCGTTCGTCTGCCTGTTCTGCGGCCGCGCTTTCGgcggcaaatcggatctgacgCGCCATCTGCGCATCCACACCGGCGAGCGGCCGTACCACTGCGAGTCGTGTGGCAAGTGCTTCGCCCGGGCCGATTATCTGTCCAAGCATTTGACCACCCACATTCACAATGCGCCGCGCTGA
Protein Sequence
MSAMAASRCPTPFAFPFSPLGLSLFDIDPSRILNLLHHQTWLAEEALRTRGLLSAPKDFPHRFTTLSDLLTKDYQPTAASYAAKQTQSTTSRSSDPQYKQQQQQQPSQQQQQQQQAQPHGAFNMRYATPTGFFQPSKGGKSAGTPSPQQMATSSTAISAESQLEGQSEGNDDVTIVELGSERSVVTPNSSALLYKESLEQLLAQQQQHQQQRRRNANNSTPSTGSVGAGAGSGAGAGAGAGAGAGVIVDASGLRQYTQLLLSGGGTPVSCTDTSSSCKEKSSSSSTSSTPPPSGALLAQHQQLSQMLKSPSDTCSSLFSEPIEEETRCVVCNAHFPNVWLLEQHAALQHPHIGPGEEKPFICEQCGQSYRYRSAYAKHKEQNHRARLPADKLFTCDVCGMQFRYLKSFKKHRLNHALERLHGKKSIGVGVGVGVARMISGTAAATAAAAAAAAATSAQLDQDVVTSSQEPMLADEGEDLRINVKREGDDPAHQQEATSDEHEQDNTIDSAGITMLYNDNNSSASASTSATEPNISSSDGIHSTNKRSRLLNSGHHLETDPSYHHQQHHHHHQQQQQQQQQQQQQQHHHHQQQSQSQSQQLPPHLAHVSLPMASAAAGSSSAAAAAAAAAAGCNSSPGAGAAGAANSVVGGSGISSLSSLTSLINAERIPNEQFLGLNPQEASILNFLRVDAAERQRDKRPTTSRFACPFCGKCVRSKENLKLHVRKHTGERPFVCLFCGRAFGGKSDLTRHLRIHTGERPYHCESCGKCFARADYLSKHLTTHIHNAPR