Basic Information

Insect: Drosophila fulvimacula
Gene Symbol: ken1
Assembly: GCA_035045555.1
Location: JAWNOX010000203.1:12606086-12608482[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.068 4.7 7.9 5.9 3 23 255 275 253 275 0.96

2 12 0.0003 0.021 15.3 0.5 1 23 281 306 281 306 0.94

3 12 0.002 0.14 12.7 1.2 1 23 313 338 313 338 0.93

4 12 0.00096 0.066 13.7 4.0 1 23 348 370 348 370 0.97

5 12 0.0019 0.13 12.8 2.2 1 23 377 399 377 399 0.97

6 12 0.0074 0.51 10.9 0.5 1 23 405 427 405 427 0.97

7 12 0.039 2.7 8.7 3.5 1 23 433 456 433 456 0.97

8 12 0.019 1.3 9.6 4.1 1 23 462 484 462 484 0.95

9 12 0.0094 0.65 10.6 2.3 2 23 491 512 490 512 0.96

10 12 0.00019 0.013 15.9 0.8 1 23 601 624 601 624 0.95

11 12 0.00038 0.026 15.0 0.8 1 23 630 652 630 652 0.95

12 12 1e-05 0.0007 19.9 2.3 1 23 658 680 658 680 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.068	4.7	7.9	5.9	3	23	255	275	253	275	0.96
2	12	0.0003	0.021	15.3	0.5	1	23	281	306	281	306	0.94
3	12	0.002	0.14	12.7	1.2	1	23	313	338	313	338	0.93
4	12	0.00096	0.066	13.7	4.0	1	23	348	370	348	370	0.97
5	12	0.0019	0.13	12.8	2.2	1	23	377	399	377	399	0.97
6	12	0.0074	0.51	10.9	0.5	1	23	405	427	405	427	0.97
7	12	0.039	2.7	8.7	3.5	1	23	433	456	433	456	0.97
8	12	0.019	1.3	9.6	4.1	1	23	462	484	462	484	0.95
9	12	0.0094	0.65	10.6	2.3	2	23	491	512	490	512	0.96
10	12	0.00019	0.013	15.9	0.8	1	23	601	624	601	624	0.95
11	12	0.00038	0.026	15.0	0.8	1	23	630	652	630	652	0.95
12	12	1e-05	0.0007	19.9	2.3	1	23	658	680	658	680	0.98

Sequence Information

Coding Sequence: atgaatGAGGGGAGTGAATACTCCATACATTCAATATGTCGCATATGTTTAAACCATTTGCGCAACGATCCGGCCTACGACCTTTTTCTTGTCCCTGGTCTGGCCAAGAAACTTTGTGTGTGCACTTCACTCTCAGTGGAACAGCACGATGGTTTCCCGAAAAACCTTTGCTCCACCTGCTATACCCGGCTCAACGACTTGCATGGTTTTCAGAAACTTTGCGTGGACTCTGCACAAAAGTTTCAAGAAATGGTGgccaataattattttacaccTGTAATTGCTGATATTAATCAAATCGACAATGTCGATATACTGCAAGTACCGCCCCCGGATGGAGAAATGGAGGAGGACCGCATTAACTTCGACCCACTGCTGAATACCAAAATAGAGATAATTGAGAATGAGGAGGATGTCTTTAAAATGCTGGAGGATGTTGACAAAGATGTGGAGGAAGTTGAGAAGGGGAAGGACTCTTCAAGCGAAAGCGAAGCCGAaaatgacgatgatgatgttgacTTTGAAGCAAATAGCAGCGAATCTGACGACGCCATGCCCTTATCACGTTTGCGTAGCAGCACCAGAGCATCCAAatcaaaggcaaagaaaaaacGTGATGAAAATGATGATGATTCTTCTAGCTCTGACTCTGacaacgatgacgatgacgatgatgatgacgacgaagaCGATAAGCCCAAAACGAAACCAAAACGCAAACGCATTCCGGCCGCTGAGCGCCACCTTCACCGTCTAATCGATTGTCACATATGTCACCAGAAATTCAAAAAGGCAATTCGCTATGAGGAGCACATGAAGCACCACAACGATCTGTTGCCATTCCAGTGCACTGTGGAGACCTGCAAGAAGGGCTTCACCACGGCTGGTGGTCTACGACTTCATATGGATCACGCCCATTCTGAGTTCTCTGAGGTGCACGCCTGCACATTCGAGGGATGCGATAAGACATTCCCCCGTTCCGTATTGCTCACGTTTCATATGAAGAAGGTGCACAAAGTGGCCAAGGCCGATACTCGCAATCACCCGTGTACTGAGTGCGAGAAAGTTTTCCGTTGTCCAACAGCGCTTAAGAAGCACATGTACAAGCACACAGGCGAGGAGCTGCCATTTGCATGCGAAATCTGTGGAAAACGATTCCATATTCACAGTGTGCTCAGGGATCATCTCTTGCGTCACGCTGGCGTCAAGAATCACGTGTGTCCTTATTGTGGCGTGGGCAAGACAACTCGCCAGGAGTGGAACAAGCATATATTGACACACACCAGGGAGAAGCAGTTCCAATGTCGTCAGTGCGATCATTCATCTCATAACAAACAGGCTCTGTCTAATCACGTCAAGGTGGTGCACATGAAGATCAAGAACTTCGCTTGCCAATATTGTGGCAAGACCTTTGGCAAATCGCACGCCTGCAAGATCCACGAGCGACTCCACACTGGCGAGAATTGCTGCGAGTGCAAGATCTGTGGCAAGATCTTCCTTTTCGAGAAGCGTTTGACTAAGCATTTGCAGATTCACGAGAAGCGTGAAATACCACCGCCATCAGCTACTGGCAATCCGACAGTCGAAGGCGATGCACAAAATACGCAGAATATGAACCAGGAAATGACAGAACCTGTGGACATTAAGCCCGTGCCAATAGTTCCACCTAAGCCCAAGAACTCCCATAGAGTTGAGCGTGTGGATATCTCTCAGCTGGCTGGCACCTCTGTTAATCCCATATCTTCGGTTTCGGTGCCATCCTGGTCGCCACAGGTGAACTTCACCAAGAAGGAGGGCCAGCACATTTGCCCAGGATGTGGACGCGGCTTCAACCACATTGGCAATATGAAACTTCACTACAAGATCATTCACGAGAAGGTGAAAGACTTCGCTTGCCGCTACTGTCCCAAACGCTTCGCCAAGGCGCAATACCTGCGCAACCATGAATATATCCACACGGGCGAGAAGCCTTTCGAATGCAAGATATGCGGCAAACACTTCCGTCAGGAGCAGGTGTTGAAGACGCATCTGAAGGTGCACGACAAGCCGCCGAAACCGCCAAAGGTCAAGAAGCCAACCAGACCTTCTCTTAGCAAAGCCAAGGGATTGAAAGTCGAGCTCAATAAAAAGCAACCAAAGATATTCGACGAGTTCCAGGATCCCGCTGCAGAACGTGCTGCCGCCACAGCTGCACTGCTCGCCCAGCAGATGGAGGAGAATGAGGCGAAGCGCAAGGCCGAGGAGGAGACACGTAAGATTCAGGAGGCCGCATGCGAGCAGCTCAATCGACTACAAAAACAGGTTCAAAGTGAGAAGGGCTCCTACGATAGCTACTATGGACAGAAGGCAGAGGCTGAGGGGACTAGCATGGATGCCCTTAAATTAGATCATGTATAA
Protein Sequence: MNEGSEYSIHSICRICLNHLRNDPAYDLFLVPGLAKKLCVCTSLSVEQHDGFPKNLCSTCYTRLNDLHGFQKLCVDSAQKFQEMVANNYFTPVIADINQIDNVDILQVPPPDGEMEEDRINFDPLLNTKIEIIENEEDVFKMLEDVDKDVEEVEKGKDSSSESEAENDDDDVDFEANSSESDDAMPLSRLRSSTRASKSKAKKKRDENDDDSSSSDSDNDDDDDDDDDEDDKPKTKPKRKRIPAAERHLHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVETCKKGFTTAGGLRLHMDHAHSEFSEVHACTFEGCDKTFPRSVLLTFHMKKVHKVAKADTRNHPCTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFHIHSVLRDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTREKQFQCRQCDHSSHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKIHERLHTGENCCECKICGKIFLFEKRLTKHLQIHEKREIPPPSATGNPTVEGDAQNTQNMNQEMTEPVDIKPVPIVPPKPKNSHRVERVDISQLAGTSVNPISSVSVPSWSPQVNFTKKEGQHICPGCGRGFNHIGNMKLHYKIIHEKVKDFACRYCPKRFAKAQYLRNHEYIHTGEKPFECKICGKHFRQEQVLKTHLKVHDKPPKPPKVKKPTRPSLSKAKGLKVELNKKQPKIFDEFQDPAAERAAATAALLAQQMEENEAKRKAEEETRKIQEAACEQLNRLQKQVQSEKGSYDSYYGQKAEAEGTSMDALKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610124;
90% Identity: iTF_00508555;
80% Identity: -