Dful013029.1
Basic Information
- Insect
- Drosophila fulvimacula
- Gene Symbol
- -
- Assembly
- GCA_035045555.1
- Location
- JAWNOX010000202.1:201915-203238[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.008 0.55 10.8 3.3 1 23 187 210 187 210 0.97 2 8 0.044 3 8.5 0.1 2 23 217 239 216 239 0.96 3 8 5.7e-06 0.0004 20.7 1.0 1 23 242 264 242 264 0.97 4 8 6e-06 0.00042 20.7 4.4 1 23 270 294 270 294 0.97 5 8 0.0002 0.014 15.8 0.9 1 23 300 322 300 322 0.98 6 8 2.3e-05 0.0016 18.8 2.3 1 23 328 350 328 350 0.98 7 8 0.00074 0.051 14.1 3.0 1 23 356 378 356 378 0.96 8 8 8.2e-06 0.00057 20.2 0.1 1 23 384 406 384 406 0.98
Sequence Information
- Coding Sequence
- ATGTTAAAGCAGTGCCTAATCAATGTGGACCTATCGCGGCTGCATGCCAATCAGCAACGGCCCCCAAAATGTGGAGAAATATTCTACAAGGGCGAAAACGAATGCAGCAGCTTCCAGTTGGTCTGTTGTCTCTGCGAAATGAAGCATTTTACCTTCGACGACTTCTCGATGCACATACGCAATGTGCATTTCACCAAGCAGGGCAAAACATGTAAAACcgataataattatacatgTGAACAGCTGCCGATTGTAAATGCAACATTACCTGCAGACAACTTCGAGCGCAGCGATGATCCATATGAAGATGAGAACGTCGCTGATGCAGCGACCGCTAAATCACTGCGTGTCTGTCCGTTCAATGACATCAAACTTGAAAATCAGCTATTGGAATCCAACGAAAAGGACCAGGATGAGGACAGTTGCGCTAAATCAGCCGAACCGGACACAGCTACAGCAGATGCCCAGAACTGtactgatgatgatgatgataacgaCGATGCTGTTGATAGTGAACCGGAAACGCAATATGTATTTAAGaAAGAACAACCCAAGGagcacaaatgcaaatactgTAACGGCAAGTACGTGAGCCTTAAGTACCTAAATATGCATGTAAAGATAAAGCACCCGTATCCGAATGGCATCAAGTGCACCGATTGTGATGCCATCTTTGACGGGGACCGCGCCATGCTATCGCATCGTCGCAGGGTTCACACAGAGTTCACGTGTAACCTGTGCGACAAGGTATACAAAAGCTCACGCACTCTTCTACGCCATGTGCAAGGACACTCGGGCCTACGACAGTTCAAATGCGAGCACGAGAGTTGCGGCAAATCCTTCGTTAGCCAGCATAACTTAACGTCGCATCGTCGCATCCACAGCACAGAGCGCAACTATGTGTGCGAACTATGTGGCTATCGCTCGCGCTACCACGATGCACTCGTCGTTCATCGACGCTCACATACGGGCGAGAAGCCGTTCAAGTGCCAAACATGCGCACGCTGCTTCGCTTCCAAATCGCTGCTCAATGAGCATCAGGCCATGCACTCAACGGAGCGGCCCTACAAGTGCGACAACTGCGAGGCCGCATTCTCACGTCCCAAAGCTCTCTACCACCACAAGCATCTGCATTTGGgcataaaaaagttcaagtgcaAAGTCTGTGGTAATACGTATGCCCAGGCAGCGGGGCTCTCGGCTCATATGCGTGGCCACAAAGCCGCCAGTGGCATTGTAGATAGCGGCTCAACTCTCGCCTGTCCACCCCGTTAG
- Protein Sequence
- MLKQCLINVDLSRLHANQQRPPKCGEIFYKGENECSSFQLVCCLCEMKHFTFDDFSMHIRNVHFTKQGKTCKTDNNYTCEQLPIVNATLPADNFERSDDPYEDENVADAATAKSLRVCPFNDIKLENQLLESNEKDQDEDSCAKSAEPDTATADAQNCTDDDDDNDDAVDSEPETQYVFKKEQPKEHKCKYCNGKYVSLKYLNMHVKIKHPYPNGIKCTDCDAIFDGDRAMLSHRRRVHTEFTCNLCDKVYKSSRTLLRHVQGHSGLRQFKCEHESCGKSFVSQHNLTSHRRIHSTERNYVCELCGYRSRYHDALVVHRRSHTGEKPFKCQTCARCFASKSLLNEHQAMHSTERPYKCDNCEAAFSRPKALYHHKHLHLGIKKFKCKVCGNTYAQAAGLSAHMRGHKAASGIVDSGSTLACPPR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -