Dful010896.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila fulvimacula
Gene Symbol
-
Assembly
GCA_035045555.1
Location
JAWNOX010000192.1:339870-342747[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0074 0.51 10.9 0.7 2 23 143 165 142 165 0.92
2 12 6.4e-07 4.4e-05 23.7 1.4 2 23 179 201 178 201 0.96
3 12 0.36 25 5.6 8.8 2 23 471 492 471 492 0.97
4 12 1.2e-06 8.3e-05 22.8 2.8 1 23 498 521 498 521 0.96
5 12 0.0021 0.14 12.7 0.4 1 23 526 549 526 549 0.96
6 12 0.00015 0.01 16.3 4.6 1 23 567 589 567 589 0.96
7 12 0.00013 0.0087 16.5 1.6 1 23 594 616 594 616 0.98
8 12 3.3e-05 0.0023 18.3 1.7 1 23 622 644 622 644 0.95
9 12 0.00011 0.0078 16.6 1.8 1 23 650 672 650 672 0.98
10 12 3.4e-07 2.4e-05 24.6 2.7 3 23 680 700 679 700 0.99
11 12 2.3e-08 1.6e-06 28.3 1.0 1 23 706 728 706 728 0.99
12 12 1.5 1.1e+02 3.6 5.2 1 19 733 751 733 756 0.88

Sequence Information

Coding Sequence
ATGCCTGACACCTACGACCAATTCGATGCGGAGCGCGTCTGCCGTGTTTGCCTGCGCGAGGTGGGCGATTTCTACTTCATCTACGATGAGGCGCCCGTGGAGCAGGGCGCGAACATCGCCCAAATACTTAACGAATGCACGCGCTACACCTGCGAGCGATATGATAAGATGCCCCATCATATGTGCGACACCTGCATTAAGGCCGCCTGTCAAGCGTATCGCTTTAAGCAGGACGCCGAGAAGGCATATCGTTCGCTTGTGGCTATGCTCGGCCGCACACCTGTGACCAAGCCCAACAGCAGCGACGTCTGCACCCAGACTGAGCAGTTACCTATGCTGCCGTGCGGCATCTGTAATGATAAATTTCTCAACATTCTCGAATTGCGTCTGCATCGCAGTAGCCAGCACTTGAATATGGCGGAGCTGAAGTGCAGCCTCTGCGATGAGCAGTTCCAAAAGCTGCGTCAGCTGCGCACTCATCTCGCCGAGCAGCACGATCAGAAGCCAGCGACGCCGTGGCTACGTCGACGTCTGGAATGTCGGGTTTGTCAACGCGCGTTCTCGCGACGTGATCATCTCATTCGTCATATGCGCAGTGCGCACGATGTGCCTCAGCCGCATGAGCCGGAGTCTGAAGCGAGTTGGACGCCCAACGACGAGGCAACGATGCAAAGCGGCGATGAACTGGAGTCGGCTGCCGTCCTATTCAATGATCCCGCTGCCTGCTCCGACAACGAAAACAACGAGAGTGGCTATCAGTGCCATACCACCAATCCCATATCAAGCAATGAGGATTCTGGCGATGATGAGGTGCATGCCGAGGCTAAGGAGTCGCTCTGGTTGCACAttaagccagagccagagccagagctggAGGCGGAAGCGGAGGCGGAAGTTGAGCAAGTGAATCCCGACAGGcgcaaaaggaaaacaaatttaaaggcCGTAGTTCGCACAGATGCAGAAGAGGATGCTGAGAACATTAGCAAGCCGAAGCCAGCTTCGTGTTCATTCTCAGCAGAGGTAAAAGAGGAGCCGCTCACTGCCGGCAGCGAGCAGCAGTTGTCCATTAAGGAGGAACGACAGCGCGTTGATAGCATCAAAATGGATGACGAGTATGAGATGGAGGCGGCAACAGCTGATCTGTTTCACAGTGCtgacgaggaggaggacggTGAAGAGGAGACTGACATTGATGGAGAggacgacgaagacgaagatggagatggagatggagatggagatggagatgaggatgaggaggaagCGAATGCAGAGCTCGACGAGCACAAATCGAAGCTGAGTCAGGTGGAAATCGTGCGAGAGTATTTGCAAAAGCCGACAACGGGCAAGCAGCGACGCCGGCGACGGAAGAAGACGCAAAGCGAGATGGAAGCAAATCCGGAGAATCGGTGCGATGTCTGCATGCGCACCTTCTCCCGCCATTGCCATTTGCTGCGACACAAATTGTCGCATCTGGAGAAGAAGCCTCACAGCTGTCCGCATTGTCCCAAGGCCTTTGCGCGCAGCGATCACTTGAAGGCGCACGTGCAGAGTCTGCACGGCAACAAGGAGCACAAGTGCGTGCTCTGTGATGCGGCGTTCGCCCGCCTCGACGCACTCGACCGGCACAAGATGAGCAAGCACAATGGCGAGGGACTCGACGCCAGCAACGAGCTGAAGCTCCAGATGAGCGAGCACACGTGCGAGTACTGTGCGAAGCGCTTCTCCAGCAAGACCTACCTGCGCAAGCATACGCTGCTACACACGGAGTTCCTGTACGCCTGCAAGAGCTGCGACGAGACGTTCAAGGAGCGCCAACAGTTGCGCAGCCACGAGAAGACCCACACCGGGCAGCGTAACTTCCTCTGCTGCATTTGCGGCGATAGCTTCGCGCGCAACGACTACCTGCGCGTCCACATGCGACGCCACAATGGCGAGAAGCCATACAAGTGCCATTACTGCATCAAAGCATTTCCACGCGCCACAGACCTTAAGGTACACGAGCGGTACCACACGGGCACCAAGCCCAATCTGTGCAACACCTGCGGCAAGAGTTTCCATCGTGCCTACAATCTGACCATACATATGCGCACCCATACGGGCGAACGTCCGTATAAGTGTGATCAGTGCCCGAAGAGCTTCAGCCAGAGCAACGACCTGAAGGCCCACATTCGCCGGCATACTGGCGAGCGTTACAAGTGCCCGCACTGCGATGCCTACTTCCTGCAGCTCTATCACATGCGCAACCATTGCCTGAGCGCGCACAACAAGCATATTGAGACGAAGACGGGCCGACTGCAGCGCACCGGCCTGCTGGACGAGGCCAATCACTCGCATCTGACCACTGTCGTGATGCCGCCGGCACGTTTCCAGCCAACGACGCCCGATCCGCAACCGGTGGCCACTGTTACAACGCAGCTCTCAGCGGCAATAGCCACGCCCATTATGCATTCGCCGGTGACCTACAGTACAACGTCGCCAGTGCCCGTCTCCGTGCCACTGTCCGATGCAAGCGGCTTCGTTGGTGCAACGACAAATGCAACGAGcacaacggcgacggcgacggcccCATTCGGCAGCTTCAGCATAGCGCCCGTCGTGATggCTCATTTGATGTACAATCATGGCGGCAACAGTCAGCAGAGCAATGCGAGCAAATAG
Protein Sequence
MPDTYDQFDAERVCRVCLREVGDFYFIYDEAPVEQGANIAQILNECTRYTCERYDKMPHHMCDTCIKAACQAYRFKQDAEKAYRSLVAMLGRTPVTKPNSSDVCTQTEQLPMLPCGICNDKFLNILELRLHRSSQHLNMAELKCSLCDEQFQKLRQLRTHLAEQHDQKPATPWLRRRLECRVCQRAFSRRDHLIRHMRSAHDVPQPHEPESEASWTPNDEATMQSGDELESAAVLFNDPAACSDNENNESGYQCHTTNPISSNEDSGDDEVHAEAKESLWLHIKPEPEPELEAEAEAEVEQVNPDRRKRKTNLKAVVRTDAEEDAENISKPKPASCSFSAEVKEEPLTAGSEQQLSIKEERQRVDSIKMDDEYEMEAATADLFHSADEEEDGEEETDIDGEDDEDEDGDGDGDGDGDEDEEEANAELDEHKSKLSQVEIVREYLQKPTTGKQRRRRRKKTQSEMEANPENRCDVCMRTFSRHCHLLRHKLSHLEKKPHSCPHCPKAFARSDHLKAHVQSLHGNKEHKCVLCDAAFARLDALDRHKMSKHNGEGLDASNELKLQMSEHTCEYCAKRFSSKTYLRKHTLLHTEFLYACKSCDETFKERQQLRSHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCHYCIKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFSQSNDLKAHIRRHTGERYKCPHCDAYFLQLYHMRNHCLSAHNKHIETKTGRLQRTGLLDEANHSHLTTVVMPPARFQPTTPDPQPVATVTTQLSAAIATPIMHSPVTYSTTSPVPVSVPLSDASGFVGATTNATSTTATATAPFGSFSIAPVVMAHLMYNHGGNSQQSNASK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00532523;
90% Identity
iTF_00568398;
80% Identity
-