Dful011022.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila fulvimacula
Gene Symbol
hang
Assembly
GCA_035045555.1
Location
JAWNOX010000192.1:1708215-1723028[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.37 26 5.6 1.0 3 23 510 531 509 531 0.93
2 18 1.1 74 4.1 3.2 3 22 638 657 636 657 0.89
3 18 0.0008 0.055 14.0 3.3 1 22 755 776 755 778 0.90
4 18 0.092 6.4 7.5 0.1 2 21 790 809 789 810 0.93
5 18 0.00093 0.064 13.8 0.2 2 23 937 959 936 959 0.95
6 18 0.0027 0.18 12.3 0.1 1 23 967 990 967 990 0.96
7 18 0.0002 0.014 15.8 0.2 2 23 1076 1097 1075 1097 0.97
8 18 0.00038 0.026 15.0 2.9 2 23 1199 1221 1198 1221 0.97
9 18 0.03 2.1 9.0 0.2 2 23 1230 1252 1229 1252 0.95
10 18 0.00059 0.041 14.4 0.2 1 23 1265 1288 1265 1288 0.97
11 18 0.00017 0.012 16.1 1.1 1 23 1330 1352 1330 1352 0.99
12 18 0.0026 0.18 12.4 0.9 1 23 1360 1383 1360 1383 0.96
13 18 0.09 6.2 7.5 0.4 2 19 1391 1408 1391 1409 0.94
14 18 3.5e-05 0.0024 18.2 0.4 3 23 1514 1534 1513 1534 0.98
15 18 0.0067 0.46 11.1 0.1 1 23 1569 1591 1569 1591 0.97
16 18 0.00079 0.055 14.0 0.6 2 23 1685 1707 1684 1707 0.93
17 18 0.0085 0.59 10.7 0.3 3 23 1763 1783 1763 1783 0.98
18 18 5e-05 0.0035 17.7 2.3 1 23 2228 2250 2228 2250 0.99

Sequence Information

Coding Sequence
atgtgCGACGCTGtcgcaacagcaataacatcAGCAGGAACAATGCCGGCAGGATCAGGAGGAGTGTCTGCTGGCGACAGCACATTGACAGCCGTGGAGGAGCGTCAGCGACAAAGTTGCTGTCGTCTTTGCATTGCGCCCGCCAGCGAATGCATTTCGATCATTAACAGTTATGCGGCCGATAAGGAACCGTTGGCCACTAAAATACACAACTGCGTAAATATCAAGaTCACGCCATTGGATCGTCTATCGCTGCACATTTGCCATGCCTGCATCAGCTATTTGAACTCCTGGCAGAGCTTTAAGAATCGCTGCCTCAGCTCACAGACGAAGCAACGGCAATGGCTGGAAAGCGATAAAAGCAAGCAGCAGACACTTTTGGGTTACTTGGATTTGAACAAAACGGAGAATGGCAGTTCCATtgaacagcagcatcaacagcagcaacaacagcagcagcagcagctcgaatCGAATATCGATTCGGCGACGATTGCAGCTGAAAAGGCGTCCGCCAACATTTTGGATGGAATTCCTTCGTTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCaaagcaacagctacaacagcaacatcaacagctacaacaacaacaacagcaacaacagcagcagcagcaacaacaacaacagcaggtgCAGCATGCTGCAGCAAGAGCAACGAGCGCGGCGGCGGAATCACAGCAAACGCTGCAAACCCTTTTATTGCAGGTGccctcaacagcagcagcagcagcattggcaACGACGTcgacgcaacagcagcaacagcaacagcgcaaatatcaacagcagcaacgtgtcaagcaacaacaacaacaacaacaacaacattaccaacaccaacaacatcaacagcagcgctTGAGTCGCATTCGTCAGCCGCGACGCCAGCAACAGGCGTCAATGTCTGGCCAGCGCATGGTCAAATTTAAACCGAAACTGTATTTGCCACTGGATATATCGgtgccgccgctgccaccgcTGTTGCCGGCACAGCCGTCGgacactgttgctgctggtgctaaGTTGGCGCCGTTGCCtgtgccgttgccattgcctttgCCACTTGATTTtagccagagtcagagtcaacAGAAACATGGCAGCgtgttgccattgccgccgccgctgccagctgcaACAATAACTAGCAACGCCGCTGCCGCTACCTCtagctctgccgctgcctctgtcgCAACCGCAGCCGCAGTCACGACTCCACTGCTCATGCCGCCGCTGCCCGCTGTGCCAATCAAGGATGAGCCCATTGACGATACGGACGATGACTTTCAAATGAAGTGCATAGACGAATCCGATGATATGATGGATCCAACAATGTTCCTAGAGCGCTCCGAGCATGAGGGCGATGTACCGCTAATGaCCTCCGACTATGATTACACGGCGCAACACGGCGTGACGGCGGTTGCGGCGGCGGCATCACTGCCCGCCAGCGCGGTTGCAAACGTGGCCGCCGCCGGCGACTCAAAGGTGGCCAGCTGCCGTGCCTGCAGTCTGCAGTTCTCGACGCGTGCGAACGCCCGACGCCACGAACGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGACTCACCAAATAATACGCCGATCACAAAGCCAACGCCGGCACTGGCCGCCGCACTGGAAATTCAGCgtgccgcagcagcggcagcagccaccgCGGAGGCAACCAAAGCCGCCGCTGGCGGCAACATATCAGCGCAAAAGTACCGCCAGGTGGTAATGAACACGTTCATCAAGTGCGAAAATGGCGGCTTCGACTACGACAATCCGGAACAATACCAGCATCTGCTCACCCGCGACAAGGTGGAGTTCATACAGGAGAACAATGAGTTTCTCGAGCAATACCAGACGATgacctgccgctgctgcaacaaatatttcaacaccTACAAGAACTTCATGGCGCATGTCCGGAAGAAATATCCCCAGCTGCCGCGCAACTTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTCAAGAAGCGCAACTGCATCAACTTGTACCGCGTGCTGAACGCTTTGCGCTTAAAGCTGCCCAACTTTTCGCATGCCAACGCAGCCGGCGTGGCTGTCTCGTCGGATTTAAGCTTGGTccaggcagcagctggagcggcTGGAATGAAACATGATACGTCCGCGGAGCGGCCAGAGAAGCTGCGTGCCAAGGAGCTGCTGGTGAACAAGCTGTACGAGTGCAAGCTCTGCCCGAAGGGCTTTCGCACCAAGCACGAGTTCCGCACCCATGTGTACGACAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGGCTGGACTTTGCCGATCCCGTCGACCGACGTCGTCACTACAACAATATGGAGTGCATTGTGCGCCTGCGCTGCATGACCTGTGATGCCAAGCTGGAGACGCATCAGCGCTTTCTTGACCACGTCTACCAGGACCATCTGGGCGGCGTGAGCAGTGATAATGCATCGACGGCTAACAGCGGCATGGATCATTCCCCGGGCAAGCGGAGCCTGCTCGGCGCCCTGGGCATTGGTGTCAGCCAGTCATCGAACGACGAGTCGCGCAGCAGCactcacaacaacaacaatgctgtGGAATTGCCCTTTACCTCAACACCGAAACCGGCGGGCGGAGCAGCTGGCGGAGCAGCGACgagtggcggcggtggcggcggcggctccaGTCGAGATGCACCCAAATCGCAGTATTTTTCCCGCATGCCCCAGGTCTGCCCCATTTGTGGCCAGCagtacaacaactacaacaacgtGCTGCGTCACATGGAATCGAAGCATCCCAACAAGCTGCCCGAGACGTACAAGTGTGTGCGGTGCGGCCTTGGCTATCCGCGAATCTCGTACCTCCGGGAGCACATGATCAATGTGCACGGCGTGGACAAGAATCGTCATTCGGGCGGCTTTGAGTACATTGTGAACGCCGATGCAGTCAAATTGGCGGACGGCAGCACGCCGAACGTCTATACCGGCCGCTATGATTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgATGACGATGAGGAGGAAAGTGGCAGCGTTGCCAAAAAGATGCGACTggacgacagcagcaacaacagcagcatcaacatgGGCATTGCCAATCAACAGAAGGAGTGCCTCATCTGCAATGCGGTGTTCAGCAACAACATTGGCTTGTCGAATCATATGCGCTCGCATTATACAGCCTCGACGGCAACGAATGCTGCGCTGGCGGCCGCCAATCGCATGACGCCCAAGTCTCTGACAATTACTGCCACGCCGCCATTGGACACGACTGCAGCAACGTCCACGGGCattgcggctgcggctgcggctgcggctgcggcagcggcaccagccacaacagcagcggcagcaggtgGCGCAGCGGTAACGAGCGCTGGCGGCTTGCCACCCGCGATGGTGCATCAGACGCCACAGGAACAGGCCGTGTTCCGACGCAGCTTGGACCAGGCGGCCGATCGCCGCTTCCGGCGCATGCGCTGCCGCATCTGCCAGCGTCGATTCAGCTCTAAGAAATCATACCGCTATCACATGCTCACCGACCATCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTCTGCAATGCCGAGTTTGCCTACGAGAAGGGTCTGAAGGTGCATCTATTTAAGGTGCACGGACGGGCGATCAAGGACGAAATGATTATCAAGCAATTCGAATGCGATATCTGCTCAATTGTCTACAGCTCGGAGATggaactgcagcagcacaagCGCAGCGTCCACAAGTCCCAACTGGGCGCCGTTGATGGTGCCTCCAAATTAGCAACCAAATCTTCTACCGCTACCTCAGCTGCCGACCTGACCGACACAGCGGGCACGCCCGTGGCCGTGCTGCCGCTCTACTGGTACCAGTGCAAGTACTGCCCATCCAACTTCAATACCAACAAGAAGCTGGCCATCCACATCAACTCGCACGACGAGTTCGATTCGAACGATTATTCGTGCAAGGATTGCGGCAATGTCTACAGCGGACGCAAGAGCCTCTGGGTGCATCGGTATAAGAAGCATCCGCAGGTGCCAGACCCAGCCGAGTGTACGCTCTGCCGCAAGATGTTCTTTGATCGACAGATGTTGGAGAATCATACGCCCACCTGCAATCGGAAGCCCATTACGGCCACCGGCGCCCATCAGCAGGATcagaaccagcagcagcaacagcaacaacacctgcaacagcagcaacaactgcaacaacatcGCGGCATATTCAAGCATAAAACGggcgatgatgacgacgacgaggacgatgACCGTCTATTGCTGCTGGACGATGGTGTCGCTGGCAGCGATAGCAACGGTGGCAATGCGGTGATCCATGTGCCGGCCACCGCCAGCATCAGCACCAAtccaaatacaataaattccAGCACGTTGAAGATCCGCATCCCAGAGGTGGCGTGCACCATTTGTGGGGCCCGTTTCACCGACCAGGAGATGTTCACCAAGCACATACAGAAGCACGAACAGGATCTGTATGTGGACAATCCATTGGCGGCCATGTTCGATGATGGCCCAGCCGATGCTGGCCAATTTCAGGTCGAGCGCCAGAACGAGAATGGGGAATATGCGTGCGATTTGTGCGCGAAGACCTTTCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCTCATCATCGACGGCGAAGCGACAACtctgaacagcagcagcaacaacaacaacaacaacaacaacaacaattcgctGAGCTCCTCATCGATGCTGCGCGAACTGCATGCCGTGGGCCTGATgcccaaccagcagcagcaccagaagcagctgcagcagcagcaacagcaacaactgcagcagcaacaacaacaacaacagcggaaCAACACGTCGAGCAGCTCGAGCAAGTCGATGAAACGCAAGCGTGAACTGAAATGTGAATATTGCGCCTCCACATtcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAACCTGCCAGAGCCGCCAGTGATTGAGGTGGACAAGCCGTTGACGTGTCGCCGTTGCGGCGACAAGCGCTTCGATACGAAAGAACTGTGGATCGAGCACAAGCTGGCGGATGCCAAGGTGGTGCGTCCCTTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTACTTGTCGCGCAAAGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTGATAGTGCCTGTGGCGACGGCCAAGGCACCAGTCGTTGCTGTGCTGCCCAACAAGAGTGCAGCGGCTAAGACAACCGCTggaacaacaacgacaacaactgcggcagccgcagcagcagcagcagcagcgacagcaggaGCAAAGGGTGGCATAATTCGAGCGGCGACAACACCAGCTGGCGGCGGTAGAGTTAATAAGAGTAAACAACTGGAGGAGCAGCTGACGATGAAGGTGGcaacgaaacaacaacaacaacaacaacagcaacagcaacaagcgtCAAATGTTGCCAATGCTGAGCAGGATGATGAGGAGGATAACAGTGATatggacgacgacgatgatgatgatgatgatagcGATAGCGGCGATGGGGATAGCTCAAGTggtgacgatgatgacgacgacgatgatgatgatgatgagggcgacgtcgacgacgacgatgatgaggaCGACAAAGATGTTGTCGCCCGACAATTgatgcaacaaaagcaacaacccCTCAACAgcaatgatgacgatgatctCATTGAAGAAGTCATCGAGGATGATGGCATCGTCGAGGAGctggacgacgatgatgacgaggaTGAGGACGATGATGATGGCAACACCACAGATGAGCACCACCAGCTGGCAGCCAATAACAGTGCAAATCAGCAGGAGAGACGCCTCAACTTTGACTATTCGCGCGCCAATCTGAACGGTACTGGCAATGGCAAGCAGACGCTGGCCAAGCAGAAGGGACAGCTGGTGATGCACAGCTCCgaggacgacgatgatgaggaTGGTGATGTCAAcggggaggaggaggaggatgatgacgatgagggCGTAGGTGAAGCAATGACCATTGATGATATTATTGAGGAAGACGATggtgaggatgaggatgaagaTATGGTTGGTGTCGATGGCGGTGTTGTtgaggacgacgacgatgatgatgttgaagaaatggatgacgatgacgacgaagatgacgacgaagatgacgacgacgacgacgacgacgacgacgacgacaatatTGGCAACAATAGTCGTCGTCGCGACGGCGCTGTGATGGTCAGCGGCATCGGCATTGGCGACGGTGAGCCCGATGATGCCGATGCggatggtgatggtgatgcGGATGGcgatggtgatggtgatggcGACGGCGATCCGGATGGTGATGTGGATGCTGATGCTACATCATCATCGGAGAGcgagtcaacaacaacaacatcgcaTTCAATTGGTGAGCGGCGTAAAAAATCAGTAGTTAAATCAGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCccaggagcagctgcagtcACATATTAAAAGTCATTTTCTCAATGGGCCGTCGGCGGGTGgcggcgccagcagcagcagcagcagcagtagcagcgccggcggtggcggcggcggcggcggcagcggcggcaacagcagaagaatcggtgcgagcagcagcagcaacagcagtagcagcagcagcaacaggaccaacaacaacaacaacaataatagtaataataataataataacaataataacagcaaaagTAAAACCAAAAAGTCCGGCTTGGATGCAACGAAAGGAGGTgacagtgctgctgctgctgctgctgctgctacaacagcaacagcaacaacaacgacaacgacaacaacagcagcagcagcaacagtggcCGCAGAAGCAGCTGCCGAGCCAGCAAACAGCTTGAACTGA
Protein Sequence
MCDAVATAITSAGTMPAGSGGVSAGDSTLTAVEERQRQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITPLDRLSLHICHACISYLNSWQSFKNRCLSSQTKQRQWLESDKSKQQTLLGYLDLNKTENGSSIEQQHQQQQQQQQQQLESNIDSATIAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQHQQLQQQQQQQQQQQQQQQQQVQHAAARATSAAAESQQTLQTLLLQVPSTAAAAALATTSTQQQQQQQRKYQQQQRVKQQQQQQQQHYQHQQHQQQRLSRIRQPRRQQQASMSGQRMVKFKPKLYLPLDISVPPLPPLLPAQPSDTVAAGAKLAPLPVPLPLPLPLDFSQSQSQQKHGSVLPLPPPLPAATITSNAAAATSSSAAASVATAAAVTTPLLMPPLPAVPIKDEPIDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQHLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPQLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKLPNFSHANAAGVAVSSDLSLVQAAAGAAGMKHDTSAERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMECIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGVSQSSNDESRSSTHNNNNAVELPFTSTPKPAGGAAGGAATSGGGGGGGSSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEESGSVAKKMRLDDSSNNSSINMGIANQQKECLICNAVFSNNIGLSNHMRSHYTASTATNAALAAANRMTPKSLTITATPPLDTTAATSTGIAAAAAAAAAAAAPATTAAAAGGAAVTSAGGLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDICSIVYSSEMELQQHKRSVHKSQLGAVDGASKLATKSSTATSAADLTDTAGTPVAVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQNQQQQQQQHLQQQQQLQQHRGIFKHKTGDDDDDEDDDRLLLLDDGVAGSDSNGGNAVIHVPATASISTNPNTINSSTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNLIIDGEATTLNSSSNNNNNNNNNNSLSSSSMLRELHAVGLMPNQQQHQKQLQQQQQQQLQQQQQQQQRNNTSSSSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDKPLTCRRCGDKRFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATAKAPVVAVLPNKSAAAKTTAGTTTTTTAAAAAAAAAATAGAKGGIIRAATTPAGGGRVNKSKQLEEQLTMKVATKQQQQQQQQQQQASNVANAEQDDEEDNSDMDDDDDDDDDSDSGDGDSSSGDDDDDDDDDDDEGDVDDDDDEDDKDVVARQLMQQKQQPLNSNDDDDLIEEVIEDDGIVEELDDDDDEDEDDDDGNTTDEHHQLAANNSANQQERRLNFDYSRANLNGTGNGKQTLAKQKGQLVMHSSEDDDDEDGDVNGEEEEDDDDEGVGEAMTIDDIIEEDDGEDEDEDMVGVDGGVVEDDDDDDVEEMDDDDDEDDDEDDDDDDDDDDDDNIGNNSRRRDGAVMVSGIGIGDGEPDDADADGDGDADGDGDGDGDGDPDGDVDADATSSSESESTTTTSHSIGERRKKSVVKSAAHGAAADQSNSSYTCDLCQLCFDSQEQLQSHIKSHFLNGPSAGGGASSSSSSSSSAGGGGGGGGSGGNSRRIGASSSSNSSSSSSNRTNNNNNNNSNNNNNNNNNSKSKTKKSGLDATKGGDSAAAAAAAATTATATTTTTTTTAAAATVAAEAAAEPANSLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00573462;
90% Identity
-
80% Identity
-