Basic Information

Insect: Drosophila formosana
Gene Symbol: -
Assembly: GCA_035045625.1
Location: JAWNOW010000763.1:1334323-1339096[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 2.7 1.7e+02 2.9 7.9 2 23 296 318 295 318 0.95

2 18 0.23 15 6.2 1.1 1 23 325 350 325 350 0.94

3 18 0.023 1.5 9.4 1.8 2 23 361 382 361 382 0.93

4 18 5.8 3.7e+02 1.8 3.0 2 17 393 408 392 419 0.75

5 18 0.041 2.7 8.6 0.5 3 23 452 472 450 472 0.92

6 18 0.0012 0.076 13.5 0.3 1 23 480 503 480 503 0.97

7 18 0.00012 0.0078 16.6 0.5 2 23 508 529 507 529 0.97

8 18 5.8 3.8e+02 1.8 0.2 1 19 537 555 537 558 0.82

9 18 0.00047 0.03 14.7 0.4 1 22 577 598 577 601 0.90

10 18 0.12 7.6 7.2 5.7 1 21 606 626 606 627 0.95

11 18 0.0093 0.6 10.6 1.0 1 23 646 671 646 671 0.96

12 18 0.036 2.3 8.8 1.6 2 23 687 709 686 709 0.93

13 18 0.029 1.9 9.1 0.5 2 23 715 737 714 737 0.93

14 18 0.0079 0.51 10.9 0.6 2 23 741 763 740 763 0.96

15 18 0.0001 0.0067 16.8 1.6 1 23 769 791 769 791 0.97

16 18 0.004 0.26 11.8 0.8 1 23 795 818 795 818 0.93

17 18 3.1e-05 0.002 18.4 3.3 1 23 824 847 824 847 0.97

18 18 0.0017 0.11 13.0 0.8 5 23 860 879 849 879 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	2.7	1.7e+02	2.9	7.9	2	23	296	318	295	318	0.95
2	18	0.23	15	6.2	1.1	1	23	325	350	325	350	0.94
3	18	0.023	1.5	9.4	1.8	2	23	361	382	361	382	0.93
4	18	5.8	3.7e+02	1.8	3.0	2	17	393	408	392	419	0.75
5	18	0.041	2.7	8.6	0.5	3	23	452	472	450	472	0.92
6	18	0.0012	0.076	13.5	0.3	1	23	480	503	480	503	0.97
7	18	0.00012	0.0078	16.6	0.5	2	23	508	529	507	529	0.97
8	18	5.8	3.8e+02	1.8	0.2	1	19	537	555	537	558	0.82
9	18	0.00047	0.03	14.7	0.4	1	22	577	598	577	601	0.90
10	18	0.12	7.6	7.2	5.7	1	21	606	626	606	627	0.95
11	18	0.0093	0.6	10.6	1.0	1	23	646	671	646	671	0.96
12	18	0.036	2.3	8.8	1.6	2	23	687	709	686	709	0.93
13	18	0.029	1.9	9.1	0.5	2	23	715	737	714	737	0.93
14	18	0.0079	0.51	10.9	0.6	2	23	741	763	740	763	0.96
15	18	0.0001	0.0067	16.8	1.6	1	23	769	791	769	791	0.97
16	18	0.004	0.26	11.8	0.8	1	23	795	818	795	818	0.93
17	18	3.1e-05	0.002	18.4	3.3	1	23	824	847	824	847	0.97
18	18	0.0017	0.11	13.0	0.8	5	23	860	879	849	879	0.91

Sequence Information

Coding Sequence: ATGTCGGAAAATGCGAAAAGCAAAGCTGAAAGTGGGCCTAGCTGCCTGCATTGCAGAGTGCACGATTCAAAACAGACATTTCAAGCGATCTTCGATGCGGTGGGCATTGAAATCGAATTGCCCACTTTGCTCACCAAGTATTTTCAACTAACTGTTAAACACGAtcccaaaaaacaacaattgttgTGCTTGGAGTGCGTAAATACGTTGATACGGTTCTTTGACATTGACGAACTGCAGCGGGAACAGGATGCCGCGAATGCAGCTAAGAAAACGAAGCCAGTCGCCAAGATTGCGGCCAAAGTGGAACCGAAGCCACCTCCAAAGAAACCGACGCCAACAAAAACCGAGCCCAAAAAGGAGCCCGTTAAATTGCCAGTTAatgcaaaagccaaagccagcaAAGCGTCCACTGGCAAGCGAGGCAATGCTAAGGAAGCTAGCTCAGGGGATCAGGAGCAGTTGGGCGCGTTGCTGCGGGACATACTCGACGATGAAAAGGCGGCATCGGCTGAGAAGTTCGTTGAGGCTGCGGAGACTGTGCGGCAGCTGGAGAACGAAAAGGAGAAACAGTTATCCGAGGAGGAAGTGgttgaggaggaggaggagcagctgctcAAGGAACAGGACAACGCCGACGAACTGGAGTTTCTTTTGGAGGGTGACTCCTCTGATATGGATTCGCCGCCCTTGAAGTCAGAGAAGCGCTCGTCACACGATGTTTCGCAATCGCAGAACGAAAGCCAAAGCGAGAACGAATCCCTCAAAGTGGAGCCCTTTAATTTTGTGCTCATCAAGGAATctgacGACGTCGGAGATCTGTATGAGTATCTAACGACTGTGGTGAAGACCTGCTTTGAGACCTTGTCCTTTGACTGGGCCACGACCTGTCAGCATTGCTCGCTGCGTTGCAGCAAATTCGAGTCTCTGCTCAGCCACATGCTCAACTGTCATCAGCTGCCCGATCAGCAGTTCAAGTGTCCCATTGGCGGCTGCCACAAGCGCCTGAAGGGACACAAGTTCCTGGCCATGCACTTGGTTGTGCTGCACGCACCCGTGGCAGAaATCCCAATTTATGGCAGCTGTCCAGAGTGCAATCTGACCTTCTCGAACATATTGCAATACAACAAACACTCCTGCGCCCATGTGATCAAGAAGCGTCGTGGCATTCGCTTGTACTGCGAAATGTGCGGTCTGGAGTTTCCCTCTTGGAAGCGcttTAACTTTCACAATCAATTTCACTTGGAGCGCCATCGGCCACGCGCCTGTTTTGTGTGCGATTATGCGGATAACAACATCGATGATCTCTTTCAGCATTTGCACTATTCACATGAACCGGAAGGCACGCTATTCTGCGATCTCTGTGATCGCACCTTTCGCGATGCTGCCATATTTACAGAGCACAACAAATCCCATGCAAATGTCACCAGCACCACGTACAGCTGCAGCGAGTGCAACGCCAACTTCGATACACGCGGTCGCCTAAATGGTCATTTGCGCATTACGCATGGCTCTGTCATCAGCTGTGAGCTGTGCAATCGCGAGTTTGCCACCGAGGCCAGCTACAACACGCACATGAAGAAGCATCTGATTATCGAGCGCGAGGTGCATGTGTGCAACAATTGCGGGCTGCTCAGCGAGAGGCATGAGAAGATGCTGGCGCATGTGGAGAACGAGAATTCGGTTTGCTTTGGCGTCGATATCTATGTGGAACTCTTGAGGGATGCTTATGTCTGTGAATACTGCTCGGCTTACTTTAAATCGAAGACAGATTTGCGTGCGCATCGCGATTCGGGGGTGCACAAGGATGGCCTCTTCTGTTGTCATCCGTGTAACAAGGAGTTTAGCGACATGAAATTGTATCGTCATCATATGCGCAACTTTCAGAACCAGCGGTCGGATGTGGCACATCGCAAGCTGGAGATTTGTCTCTACTTTATGTGTGACTACGAGGATTGCTTTGAGTCGTACATCAGTTGGAATTCGTTGTATACGCACAAGCGACGCACTCACGAAGTGCCTGAGAAACTGGACACTAAACAGAAGACCGATGAATGGATCTGTCAATTCTGCCAAAAAGAGTGTCGCTCCAAAATGTCGCTCTCGGTGCATGTGGCACGCAGTCACAACAACAACAATGTCACTTGTCAGCTATGCAAAGCGTCGTATAAGGATGATGCGGCGCTGAAGAAGCATCATGCTTACTGGCACGAGCCCATGGAGTGTTCGTTGTGCTTCAAGATTGTCAAGAATCGTCGCAACTTCGACACGCACATGAATGTCGTGCACTCGGACAACAAACGCTATGCTTGCAGTGTCTGCCAAAAGGGATTCTATCACAAGAGCGAAATGGAAGCGCACAAGCGACTTCATAATCAGTCTTACAGATGCGAGCAATGCAGCTTCACCACAAAGAATAAAAAGTCGCTGGCGGTCCATGTGCTTGGGCAGCATTACAAGCGCTTTGCCTTCCAGTGCACGCACTGCAGCAAACGCTTTGGGCGTCGCCAGGGCTTGACCAGCCACATGTTGCGAGTGCATGCCTGCAAGAAGACGTGCCGCGATTTCCTCGACGATGGCTGCAACAGGGCATTCACCACATTGGAACAGCTGAGTGCGCATGTGCGCAAGgtgcacaacagcagcatcagtgTAAGCGACGTGGAGGATGAGCCACAGGCGCAGGAGCcagaggaggagcagcaggaggccGAAGAGCAGCCGATGAAACGCAAATCGAAGCGAGCGAACACAACAACAGTGTCATCAATGCAAAAAAAGCGTTGTGTGCGCCTCAGCAATGATACGCAGATTGAATTTATTAACGCCGATCCCGAGGAGGATCCGAAGAGCGCCACGGACTCGGAGATCTTTGAGGAGTTCGAGGAGAAGCAAAGCCAAACCCTTGCCGCCGAAGCGAAAGAAAAGACaatgttaattttgttgctAAAGCAGTTAATTTAG
Protein Sequence: MSENAKSKAESGPSCLHCRVHDSKQTFQAIFDAVGIEIELPTLLTKYFQLTVKHDPKKQQLLCLECVNTLIRFFDIDELQREQDAANAAKKTKPVAKIAAKVEPKPPPKKPTPTKTEPKKEPVKLPVNAKAKASKASTGKRGNAKEASSGDQEQLGALLRDILDDEKAASAEKFVEAAETVRQLENEKEKQLSEEEVVEEEEEQLLKEQDNADELEFLLEGDSSDMDSPPLKSEKRSSHDVSQSQNESQSENESLKVEPFNFVLIKESDDVGDLYEYLTTVVKTCFETLSFDWATTCQHCSLRCSKFESLLSHMLNCHQLPDQQFKCPIGGCHKRLKGHKFLAMHLVVLHAPVAEIPIYGSCPECNLTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCDYADNNIDDLFQHLHYSHEPEGTLFCDLCDRTFRDAAIFTEHNKSHANVTSTTYSCSECNANFDTRGRLNGHLRITHGSVISCELCNREFATEASYNTHMKKHLIIEREVHVCNNCGLLSERHEKMLAHVENENSVCFGVDIYVELLRDAYVCEYCSAYFKSKTDLRAHRDSGVHKDGLFCCHPCNKEFSDMKLYRHHMRNFQNQRSDVAHRKLEICLYFMCDYEDCFESYISWNSLYTHKRRTHEVPEKLDTKQKTDEWICQFCQKECRSKMSLSVHVARSHNNNNVTCQLCKASYKDDAALKKHHAYWHEPMECSLCFKIVKNRRNFDTHMNVVHSDNKRYACSVCQKGFYHKSEMEAHKRLHNQSYRCEQCSFTTKNKKSLAVHVLGQHYKRFAFQCTHCSKRFGRRQGLTSHMLRVHACKKTCRDFLDDGCNRAFTTLEQLSAHVRKVHNSSISVSDVEDEPQAQEPEEEQQEAEEQPMKRKSKRANTTTVSSMQKKRCVRLSNDTQIEFINADPEEDPKSATDSEIFEEFEEKQSQTLAAEAKEKTMLILLLKQLI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589718;
90% Identity: iTF_00520830; iTF_00614375;
80% Identity: -