Basic Information

Insect: Drosophila flavopinicola
Gene Symbol: ZNF131
Assembly: GCA_035042425.1
Location: JAWNLL010000462.1:3228725-3245340[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.3 2.1e+02 2.7 2.4 3 23 316 338 314 338 0.92

2 14 1.4 89 3.9 1.9 3 22 488 507 486 510 0.90

3 14 0.73 45 4.8 0.2 2 23 532 554 531 554 0.93

4 14 0.2 12 6.6 0.9 1 23 571 594 571 594 0.95

5 14 3.8 2.4e+02 2.5 0.7 1 21 599 619 599 623 0.89

6 14 0.0013 0.08 13.5 0.2 2 23 685 707 684 707 0.96

7 14 0.13 8.1 7.1 0.1 1 21 712 732 712 733 0.92

8 14 0.0001 0.0064 16.9 2.2 2 23 793 813 792 813 0.97

9 14 0.00013 0.0078 16.6 0.7 1 23 819 842 819 842 0.96

10 14 0.00033 0.02 15.3 0.4 1 23 869 891 869 891 0.98

11 14 0.55 34 5.2 0.7 1 23 898 922 898 922 0.97

12 14 4.6 2.8e+02 2.3 6.2 1 23 927 951 927 951 0.95

13 14 0.0017 0.11 13.1 3.0 1 23 966 988 966 988 0.98

14 14 0.0006 0.037 14.5 3.4 1 20 994 1013 994 1015 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.3	2.1e+02	2.7	2.4	3	23	316	338	314	338	0.92
2	14	1.4	89	3.9	1.9	3	22	488	507	486	510	0.90
3	14	0.73	45	4.8	0.2	2	23	532	554	531	554	0.93
4	14	0.2	12	6.6	0.9	1	23	571	594	571	594	0.95
5	14	3.8	2.4e+02	2.5	0.7	1	21	599	619	599	623	0.89
6	14	0.0013	0.08	13.5	0.2	2	23	685	707	684	707	0.96
7	14	0.13	8.1	7.1	0.1	1	21	712	732	712	733	0.92
8	14	0.0001	0.0064	16.9	2.2	2	23	793	813	792	813	0.97
9	14	0.00013	0.0078	16.6	0.7	1	23	819	842	819	842	0.96
10	14	0.00033	0.02	15.3	0.4	1	23	869	891	869	891	0.98
11	14	0.55	34	5.2	0.7	1	23	898	922	898	922	0.97
12	14	4.6	2.8e+02	2.3	6.2	1	23	927	951	927	951	0.95
13	14	0.0017	0.11	13.1	3.0	1	23	966	988	966	988	0.98
14	14	0.0006	0.037	14.5	3.4	1	20	994	1013	994	1015	0.95

Sequence Information

Coding Sequence: ATGAACCCCGAATCTGAGGATCTGGAGGACACGCATTTGTGCATCAAGTGCAATGCGACTATTGTGGGCCTGAGCAAGTACATTGAGCACCGTAAGCGCAATTGCCTAAGTAATTCCATTAGCAATGAGCATCCGACCAAGCAAGTGGTCActcctcgtcctcatcctccGACAACAACGTCGGCAGCATCAGTTGCTCCCAGCGATCACGTGTCGCCGCCTACGATTATGAGTCGCTCCAACCTGGAGCACAGCTACGATGGCTTCCACTTTACCGAGCCGGAGGCACCGAGCAGTTACCTGCGCAAGACCACAGCCAGTCATGGCGGCAAGTCCTCCAAGTCGCTGACGGAGTCCTACGATCCCACCTACGAGCTGGGCGCCGATCTGTTCTTCTcctcgctgcagctgcagagcGTCTCGACGGGTGGGAAGACGGGTGCACGGCCCGATCGTGGAGGAACCAAGGAGGAGGCCAGCTGGCActcggccagcagctgctcggaTCCGCTGCTGAAAGCGGTGCGGGAACACGAGGAGTCCGATTTCAAGCCACTCAAGTTCGTGCACTCGCCGGAGGccagcgaggaggaggaggaggatgacgaGCCCGATGACTTCGAGGGCGACGACGAGGAACACGAACACGAacatgatgctgatgctgatccTGATCCTGATGAGGATTACGATGCGCGTCGCCATTCGCCGCCAACGGTGCCCGCCACGCACACGGGCGGCAAATGGAAGCCGGAGCATCGtccgcagctgcagcacacgCATCTGGAGCGCATCTCGCCCAGCTGGGATGAGCCGGTGGAGGAGCCGCACGATCATCCGCCCGCGGAGCACACGCACGGCAAATGGGTGCCCGGCAGCAAGCAGCTGGAGTACCGCGAGAACATCGATCTGaccaagctgcagcagccgggCGCCAGCTACTGGTGCAACATCTGCTGTCGCCGCCTCAAGACGCGCCTCAACTACGAGCAGCATCTGCGCAGTGGCTACCATCTGAGACGCGCCGATGCCGAGCGTCAGCTGGAGCAGGCGACGCTCGCCGGCGCCAATCTGACGCTCACCAAGGACTTTCAGCAGTCgaagcagcagtcgcagcccCAGtcggagcaactgcagcatcaGCCAGAGCAGCGCcaacgtcgacgtcgtcgCGCCAATCTGCTGCGCTGCGAGCTGTGCCGGCACAGCATGGCTCGCCACCTCATGGGCAAGCATCTCATCTCCCACTATCACTATCGacgcctgcagcagcagccgactCAGCTGCGCCGGCAGAGCTCGCTGCACGACATCCTCGAGCACATGGGCAGCATTGTGCGACAGGCGCCATTCCAGTGTCTTCCCTGTCGATTCTATGCGAATACAGAGCAGGCGTTCCAGGCACACTGGCGCTCCTCGACGCACGTGGAGCTCACGGAGCGACTGGGTGGCCACTTCTGGTGCAGCTACTGCCAGTGCGAGTGTGCCAGCAACGAGGAGATGTGGCAACACTTGCTCTCCGCCACGCACTTGGAGGTGCTCTTTGCCATCAATCGCTCCGTGCCCGTTTGCATTGCCCAGCGTCGTCCGATCAGCTGCTCCGCTTGCAGCGCCAGCTTCCTGTACAATGCACAGCTGCGACGACACTTTGCCACGGAGCACGTGGAACTGGAGGCGACGGGCAGCGCTGCGGATGACTATCAGTGTCGCTTTCGCTGCGGACTGTGCGGTGTGGCGCAGAGATCACGAGTGGCCCTGCAGCGGCATGAGAAGCACAAGCATCGATTGGCCAAATACTATTGTGCCGTCTGTCGGCTGGAGTTCCAGACGCCGCTGGCGGCACGGCGCCATCGTAGCCACATGCAGCACAAGCGGCGCGCATGCCACCGGAAGACTAGAAGCAAAGTCCACAATCAGCCGGAGAGGGAGATTGAGCACATGCTGCGTGCAGTGCTGGAGGATCAGGCGGAGCAGACAGAGCCGACTGAGCCGACAGAGCAACCAGAGCAGCCAGCTGCGTCCAAGCGGCGACGGCTCGCCTCACCTCAAAGCCAATGCGATCGTTGTCCTTTGAGCTTTGAGACGCCACAGGCTTTGGTGCAGCATCGTCGCGAGTCGCATCCGATGGACAATCATGCCTGCCTCAGCTGCGGCGTCAGCTTTCAGTCCGCCCAAGCGCTGGGACGGCACACTCGCAGCTGCCAGCCCACAgcctccagctccagctccaactccgcAGCAGCCGTTGCTAGCGAATCCAAAACCAAATCCTTCAGCTGCGACAAGTGCAGCTTCAGCGCTCAGTATGAGTCGGATCTGCTCTACCACAGCTTCTTTCACACGCGCAGCTCGGTAATGGGCAAGAACGAGCTGCTCCAGTGTCCACTGTGTCCCAAACAGTTCCGCAAGCACTCGCTGCGAGCCCATCTGCGTAATCATACCAACGAGCGGATCTTCGAGTGTGCCGAGTGTGCCGCCAAGTTTGCCAGGAGACACAATCTCAAGAATCACATGGCCAGCATGCATGGCCAGCCCGATAAGAAGTCATCTGTAGAGAAGACCGCAACTGTGGAGCAGCAATCGAAGGCTGTTCCCAAGCAGAAATATCAATGTGGCACCTGCGGCAAAATACTGGCTAAGAAATACTCACTGAAACTGCACGAAATGAGCCACTCGGAGTTGGAGCGTCAGTATCGTTGCCACTATAAGGATTGTCAGTATGCGGGTCTCACTCCGGAGGCACTCAAGACCCATCTCATTTCGCATGCCAAAGGAAGTCACAAATGCGAACACGACAGCTGCCGATATGTGGGCAAAAGTGAGCTGCATTTGAAGAGGCATCTCAAGTCGCATGTGAGCCAACAGGAGCCAGCTGAGGGCGGCAATGGCAATTGGTACTCGTGCGATCAGTGCGAGTTCAGGGCCCGGATCAAGGGACATCTGAGGCGGCACATGCGTCGCCACACCGGCGAGAAGCCGCATCAGTGTCCCCACTGCGACTTCCAGTGCAGCAGCCTGGACAACCTGCGCAAACACATCGTCAAGACGGGCAAGCATCCTGGCAAGTTCATCTACGAGTGCGCGTCCTGTGCCTTCAAGAGCAACAGCTTCAAGGACTACCACATACACTTGGCCACACATAAAAGCTAA
Protein Sequence: MNPESEDLEDTHLCIKCNATIVGLSKYIEHRKRNCLSNSISNEHPTKQVVTPRPHPPTTTSAASVAPSDHVSPPTIMSRSNLEHSYDGFHFTEPEAPSSYLRKTTASHGGKSSKSLTESYDPTYELGADLFFSSLQLQSVSTGGKTGARPDRGGTKEEASWHSASSCSDPLLKAVREHEESDFKPLKFVHSPEASEEEEEDDEPDDFEGDDEEHEHEHDADADPDPDEDYDARRHSPPTVPATHTGGKWKPEHRPQLQHTHLERISPSWDEPVEEPHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPGASYWCNICCRRLKTRLNYEQHLRSGYHLRRADAERQLEQATLAGANLTLTKDFQQSKQQSQPQSEQLQHQPEQRQRRRRRANLLRCELCRHSMARHLMGKHLISHYHYRRLQQQPTQLRRQSSLHDILEHMGSIVRQAPFQCLPCRFYANTEQAFQAHWRSSTHVELTERLGGHFWCSYCQCECASNEEMWQHLLSATHLEVLFAINRSVPVCIAQRRPISCSACSASFLYNAQLRRHFATEHVELEATGSAADDYQCRFRCGLCGVAQRSRVALQRHEKHKHRLAKYYCAVCRLEFQTPLAARRHRSHMQHKRRACHRKTRSKVHNQPEREIEHMLRAVLEDQAEQTEPTEPTEQPEQPAASKRRRLASPQSQCDRCPLSFETPQALVQHRRESHPMDNHACLSCGVSFQSAQALGRHTRSCQPTASSSSSNSAAAVASESKTKSFSCDKCSFSAQYESDLLYHSFFHTRSSVMGKNELLQCPLCPKQFRKHSLRAHLRNHTNERIFECAECAAKFARRHNLKNHMASMHGQPDKKSSVEKTATVEQQSKAVPKQKYQCGTCGKILAKKYSLKLHEMSHSELERQYRCHYKDCQYAGLTPEALKTHLISHAKGSHKCEHDSCRYVGKSELHLKRHLKSHVSQQEPAEGGNGNWYSCDQCEFRARIKGHLRRHMRRHTGEKPHQCPHCDFQCSSLDNLRKHIVKTGKHPGKFIYECASCAFKSNSFKDYHIHLATHKS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -