Dfla001443.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila flavopinicola
Gene Symbol
Hivep2
Assembly
GCA_035042425.1
Location
JAWNLL010000090.1:6480142-6487941[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 9.7e-05 0.0061 17.0 0.1 3 23 248 268 247 268 0.97
2 8 0.00034 0.021 15.3 2.9 1 21 274 294 274 298 0.89
3 8 0.011 0.68 10.5 0.2 1 19 937 955 937 958 0.93
4 8 3e-06 0.00019 21.7 2.0 1 23 1693 1715 1693 1715 0.99
5 8 1.3e-05 0.0008 19.7 5.3 1 23 1721 1745 1721 1745 0.92
6 8 0.0008 0.05 14.1 2.7 3 23 2190 2210 2189 2210 0.93
7 8 0.00088 0.055 14.0 1.2 1 23 2216 2240 2216 2240 0.91
8 8 0.0028 0.18 12.4 2.7 1 23 2261 2285 2261 2285 0.92

Sequence Information

Coding Sequence
ATGACGCTACAGCATGTGGCAAGCAGCGCAACGAGCGTGCccacaacgacagcaacaacaacaacagtaaacaccgccacaaacaacagcaatgtggtgacagcagcagcagtcagcgaTGAtccaaccacagcagcagcagcggcagcagcaacaattgccgATTGGACGAACTCCACCAATTTGCGCTATTTGCACAAAAAGTTCAAGCGGCTGGCCAGCACCACCGAACCGCTGGCGGACGATGCATTTCGCACCACATCGCTCTCATCGAACAGCTCGTTGTCGCCACCACCAGTGGCGCCGGCGGTGTTGCCGCTGTTAAATCCGCTGCTCAATGGGCATGTGCCGATGGCGCCACTGCTGCCGGCAAGCAATGAATTCAGTGCCAATTTCgtaaatgccaacaacaacaacaacaacagccatgatgagagcaacaacaacaacaacaataacaataataacaacagcagcagcaaaaatggtactattgctgttgctggtgcgCCCAGAACACGCACGCCCCTCAGCAACAGTAATagtaatagcaacagcaacagcaactatgcCATCAATGCAACACTGTCGCCAGCAACATTCgcacagcatcagcaacagacACAGCCAACGCCAGCAAcattagcagcaacaacagcagcagcaacaacaacagcagcaacaacaatcgtttctcaagcagcaacaacaggtgTGGCGGAGAAAATGAATCGCAACATGTGCCCATACTGCAATCAGAGCTATGCGAAGCCATCGGTGCTGCAGAAGCATATACGGGCGCACACGAATGAGCGGCCGTATCCGTGCGACACCTGCGGCATCGCCTTCAAAACGAAGAGCAACCTCTACAAACACTGCCGGTCGCGTTCCCATGCGGCACGCATGCGCGGCCTCGATGTGCCAGCCCATGAGGCGGACGGCCTCTCCGATCAGGATGGCGACGGCGGgctgagcaacagcagctctgAGCTCCTAAGCGTTGAAGTTCTGAGTCGCACAGATTCGCCTTATGACGAGCCAATGGCATCGCCCACACCTTCCCCATCGCCATCGACGCTGTCGGCTGCGAAGAGTGCGTatctgcagcagccgccgctgccgcagcacatgcaacagttgccgctggGCTCGCCCGCTGCCGGCACCCTGCCACCCGCCACAACCGACACGCTGCACTCGGCAACAGCGCAGCATCGCCAGTCGATTTCGATTGACTACAAGCCATACAAGCCCAAGTTTCACAATGCGTCGCTCTATGCGCCCGGCAGCAGcaaggaacagcagcagcagcaggtactgcagcagcaacagcagcaggtactgcaacagcaggcactacaacagcagcagcagcaacagaagttgtcaacgcagcagcagcagcaacagcagcaaccttCGCTGGCGCATCCAACGCTCTCGCCCAGCACCCAGATGAAGCTCAACAATCACATCAACTCGcatcagctgcaactgcagctacagcaccagcaacagcagcagcaacaacagcagatgCACGCACAacaatcgctgctgctggcggctgCTGCCAATCCAGTTGCAATGTCCGCTCTGCCCCCGCCGCCACCGCTGCCCGCGGGTGTCTATTATTTGGGACAGCCGCCATACTATAATCCTACGGCGTCAGCAATGCATCATCATGCGCTTGCCATACAGCAgtttcagctgcagcagcactttcagctgcaacagcagcagcagcaccatcaacagcagcagcaacagcaacaacaccagcagcagcagcagcaacaacaccagcagcagcaacactcgCCGCTGATAAAagcgccacagcagcaacagttgccgccacaacagcagcagcagcaacagCTGGTGCGCTCCAACAGTCAGCAGGCAGCAGTCatagcgacagcagcagcactgcccgcacctgccacgcccacaccgcCTGCCAATCTGAGCAGCTTTGCCAGCGCCAGCGGTGGCATGCAAGTGAATGTGGAAAAGGTGCAGGAGCACATCTCAAAGCTGATCTCACAGAACGAGGCCATTGTGGAAAACAAGGAGATACTGCTGCAGAAGAAGTATCCCAAGCAGCTGAATCGCTCGCGCAGCTTcaacaatgccaacaacagtgtcaacaacaacaacaacatcagcagcaacatcagcaatgcaacaacaataacacacgccaacaacaacagcagcaacagcaatcagCAGCTGGGCGAAACCAAAGTGAACCTGGCACAGGCCATAgtacaaaaacagcagcaacaacagcagcagcagcagcagcatctgcaacaacagctgcaacagcagcaacaataccaAATGtatatgcaacagcagcaacaacaacaacaacagcaactggagcCTGTCAATGGACTGTTAAAGcgcagcagtagcagctcGGCCAGCAGCGGTTATGTTAGCCTTAAGGGCACGCCCACTGTCACGCCCACACCCACGCCCAATgcgaagcagcaacaacagttgccgccgccgccatcgccgctgccgccgcaaCAGTTGCAATATCGACAGGATCCGGCAACGCCAGTGCCCAAGCAGGAGCTGCAACCATTGGCGCCCAATCACGCACAGCCACTGAATCTATCCGCCAAGCCCAAGCCAGCAAAGccaacagcaccaccagcgACAGCAACTGTTGTCAAGAGCACACCAACAGCTGTGCAAGCGGCTCCcaataattcaattattaaGAATCTACTGTTGAATGCACGCGGTCTGGCCGTACCGATTGGTGAGGGCGACGATGCCGTCTACTCCTGTCCCATTTGTGCTAATGAGTTTCGCAGCGCGGACGAGCTGAAGCATCACAACAGCACCTATTGCCAGGATGCGAGCAGCAGTGCGCCCATCAGTCCCGCCTCCTCACCCGGCACCAAATACTTTCGCTCCAACTCCATATCGTTTAGCCTGCCGGAGCTCAAGTCGCACATGGCCAACTCGAAGAATCCGCTGTCGCTGGCTAAGTTAGCCTGGTCACAGCTGAAGACCAAGCCCAGCAGCCTGGTGCTCAGTCGACTCAGTGCATCACAATCTCCAGCACGCACCTCAACCGTTACCAATACTagcagtagtagcagcagcagcaaccacaacaacagcaacatcaaccacagcaacatcaacaacaccaacagcaacatcaacaacaacaaccacaaccacagcagcaacatcaacaacatgccagcaactgttgctgtcaTTCCGCCCAGCATTGATGCCTCAAGCGTTGCTCTGCGCTTTGTGGACGCACCACTGCCATCGCCTGGTCCACTGCTGGGCAAAACAGCTCTGGTGGACTATGCAGCGCCACGCAAGGCGCCCGATGCCCAAGTGATCATTACGAAAATGCACGAGGATCGGCTGGAGAACATCATCAACATTGAGACGCCAACGAAACGTGCGAAGATGAGCAGCGataatgcatttgcattgccgCACGttcagctgctgtttgctggccagcaggagctgcagtaTAGCGCCAAGGAGGAGCGTCTGCGTCGCTTTACCTCCTCCGGCGGCAGCATGATACCCATCTCCGAGTGCCCCGAGCTGGACAAGAGCCCGAAGATGATACGCACACCATTGCTGTCCGGCGGCAGCTTTCAGGAGATGTCGCCACGCCTCAGCGATACCAACAAGGAGCGCAAACTAACTGCGCCCAATAATGGCTATCTGTTGAGCTCCGCAGCCACACcgcagcattttcaatttccgcCTATTAACTCCATAACTGGCTTCAATCCGCTTACGCTGCCGCCCATGAGCAATCACAGCAGCAACGATGCGAAATCGATACCTTATGTGCCGGGCATACCAGGACCCGGCAGCTTATCCTTGCTGCCGCCGCCtcagcagctgttgccgcGCGGACGCAGCCCCAATCGCAAGCAGCCCAGTCccaatccgaatccgaatcccaATCTCAATCCGTTGCTGGTCACTGCTGAGGGTCCACTCAAGGCCTTGTCGCCCTTCGGTGGTGTTCAGAATTTGCCCAGTGAATTCAGTCGACAGCCGCCGACGCCCGCTCAGCGCAATGCGCTGCAAtggaccagcagcagcaacaagacgccagcaacagttgctgctgagcTGAGCAAGAAGCTGCCGTTTAATTTTCTACGCATGGCGGATAATGTGAAGAgtcaggagcagctgcagctgcagcagcagcagcagcaggaagtgCGTCACTTTAATTTTGATAATGTTAACAAAACGCAGGAGGCGCTGGCGCCGCTGCACGTGGACACGCCGGATGAGCCGACGACAGtagcaacagttgcaactgcaacagcgacTGCCACAGCAACCGTAACAACATCAGCAATTATCATAACTTCAAGCAGCGCCAAGTCGAAGTTTCTGCGACCCACCAGTCTGCCCCTCAAGCCGGGCACCTTTACGCCCAAGCGCCATCATGGCATCACACCGACAGAGAATACCCTGCCCCTGATCTCGCCGGAAACGCCGCGACCTTCCAAGTCGTGCGTGCAGCTGTACCTCAATGGACACGCCTACACCTACCTCGGACTCAAGTGCAGCACAAAGATGTTCTACTGTACGGTGAACTGTCCGCAGCCGTCGTATGTCGCCGGCATGCACAAGCTGTCCATGTACAGTGTGTGGCAGGTGTGCGAGGAGAATCAGCCACATCCATTGGGCTTCAAGCCCAAGCAGGTGATGGCGCTCTACGATTCCAGGCAGAAGATGCTGGGCACTGGCTGCTCCACATCCATGGCGGGTACGGGCAAGCTGCACTACTCGCTGGTCAGCTCGCAGCAGACGGTCAGCACCAGTTCCACAACGGCGAATGTGCAGAGCAAGTTCTACCAGCACCAACTGAAGCAGCCACCATCCATTGGAGCGCTCAGCGAGGCCAATGTGGCGGCCAAGGCCAGCGAGGAGGCAGCCGCAGCCGAGGCCAAGAAACTGGAGTCGGGTCAACTGCTCGTTGGTGGCTACGAATCGCATGAGGATTATACGTACATACGCGGACGTGGACGCGGTCGCTATGTGTGCTCCGAGTGCGGCATACGCTGCAAGAAGCCATCGATGCTCAAGAAGCACATACGCACCCACACGGATGTGCGTCCGTTCACCTGCAGTCACTGCAATTTCAGCTTCAAAACCAAGGGCAATCTCACCAAGCACATGCAGTCGAAGACACACTTCAAGAAGTGCATCGAGCTGGGCATCAATCCGGGTCCGATGCCCGCCGACGGCGAGTTCCTCGATGTCGATATGGACTTTGATCAGCAGTCGTCCACATCTGCGGGCGGACGCACCTCCTCCATGGCCGGGGAGTCCGATTCGGATGACTACAGCGACAATGAGTCCGAGAGCAGCGATACGGATGAGTCCAAGTCGCGCATGAAGGAGCACGAGGCAGCTCGTGGTCTGCTGTCGCTATCGATGACACCGCCGATACCGCAGAGCGTGTCGCCTTATCCCGCACTGGCGCAGGACACACCCGTGCCGGCTGCGAGTCCGGCTAATAGCATTGGCTCCTCTGGCGGCTCGTCGCAGCCCAAGCGGCAGGTGTGCTCATTTACGTCGCCCAAGCCGCCCTTTGACTACCAGAAGCAGGAACAGTATTACTCCAATCCCGAGGAGTCCAAGCCCAAGCGTGCCGTGCCCAGTGACGAGAGCAGCGCCCCCATGGATCTAACCAAGCCGCGCTCAATGCCCAGCAGCATCTTATTCCAACTGCCCGAGCAGACGCCGCCCAAATCGCAGGCACAGCAGATGCGCGATGTGATCTTTGGCGCTGGCAACAACGAGTGCGGCTTCATGAAGATGCTTATCTCGGTGTCGGACAAGGTGCGCATCTCCGCTGAAATGGAGGAGCAGGCGAAGCGCGAGAGCGGCGACGGCGAGGATGTCCTACTGCAGACATACATCAAGGAGCAGGCGCTGCAGCATGCCAAAATGAAGCAGAGCCAGTTTAGTCGCAGCTATCTAGCAACCACTACTAGTAGTATTAGTAGtagctgcatcagcagcagctgtgttaGAACTCCAATCGTCAACAGCAAGCCGCCACTGATCATCACAGAGCTGCCCATCATTGAGGTGCACGAGGTGAAGACACCGGAACCGCAATCGCCTGTGGTGCCCAACGTCAGCAAATCCGCAGAGGAGAGTGAGGAGAGCGAAGCAGATCAGGAGAAGCCAGCCATTGTTGCTGTGCCTGTCTCCGTTTCCATTACGGAAACTCAGCCGCCGCACAATGCCAACTTGCCTGCGGCCGTCCAGCAGCCAGATGCCACTGATTTTAGTGGCgtgctcagcagcagcagcaacaacaccagcggcagcagcgcaacaacagcaccaacaCGCACTGTGATCGTTGGCGAGGAGGGATTCAAAGGAACACCAACGACAAGCACAAGCAATGCCGCCGAGTTgcagccaggagcagcaggcactACTCCCGTGTATCCCGGTCGCGTGGTGGCTCCGCCACCGCCACCCATTGCCAGCGATGCGCGGCCCACGTGCATCATCTGCAACAAGACGTTCCAGCGGCAGCATCAGCTGACGCTGCACATGAACATCCACTACATGGAGCGCAAGTTCAAGTGCGAGCCGTGCAGCATCTCCTTTCGCACGCAGGGCCACCTGCAGAAGCACGAACGGAGCGAGGCGCACAGGAACAAGGTGATGATGACATCGACCTTTGGTGTGCCGACCACGTCGAATCCGCGTCCCTTCGAGTGCACCGATTGCAAGATTGCGTTTCGCATCCATGGCCATCTGGCCAAGCATTTGCGCAGCAAGACGCACGTCCAGAAGCTGGAGTGCCTGCAGAAGCTGCCCTTTGGCACCTATGCGGAGATCGAGCGGGCTGGCATTAGTTTGACAGAGATCGATACGAGCGATTGCGAGAACTCGCTCATCTCGCTCAAGCTGCTGGCGCAGAAGCTGCTCGAGAAGGATCCGAATAAGCTGAGTGGCTATACGACGCCCTCGGGCATGCTGCAGCTGGCAACGGAGCCACCCGGTGTGGCTGGCCAGGACAGCGCCTCCGAGGATGGCTTCAGTGCGGCAAACAGCGCCGCCGCCTCGGCAATTGCCTCACTCGATAACGACAGTGCGGGCAACACACCGCAACGAGCCAGCTCCATGTCGGAGGACGAGACGCTCACGAATGGACTGAGTCATCGGCACACTCTCAAGCGTCGTCTGGCCggcagcagcttcagcagcAACGGCGACGAGAGCGACAATCCGCCGGAGGCAACAGTCAGCGGCAGTGAGAAGCGTGCGAGAAGCAACACAAATGAACTGACGCTGCCAGTGGCTGGAAACACGacgacggcaacggcaacggcaacggccaGCAACTGA
Protein Sequence
MTLQHVASSATSVPTTTATTTTVNTATNNSNVVTAAAVSDDPTTAAAAAAATIADWTNSTNLRYLHKKFKRLASTTEPLADDAFRTTSLSSNSSLSPPPVAPAVLPLLNPLLNGHVPMAPLLPASNEFSANFVNANNNNNNSHDESNNNNNNNNNNNSSSKNGTIAVAGAPRTRTPLSNSNSNSNSNSNYAINATLSPATFAQHQQQTQPTPATLAATTAAATTTAATTIVSQAATTGVAEKMNRNMCPYCNQSYAKPSVLQKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARMRGLDVPAHEADGLSDQDGDGGLSNSSSELLSVEVLSRTDSPYDEPMASPTPSPSPSTLSAAKSAYLQQPPLPQHMQQLPLGSPAAGTLPPATTDTLHSATAQHRQSISIDYKPYKPKFHNASLYAPGSSKEQQQQQVLQQQQQQVLQQQALQQQQQQQKLSTQQQQQQQQPSLAHPTLSPSTQMKLNNHINSHQLQLQLQHQQQQQQQQQMHAQQSLLLAAAANPVAMSALPPPPPLPAGVYYLGQPPYYNPTASAMHHHALAIQQFQLQQHFQLQQQQQHHQQQQQQQQHQQQQQQQHQQQQHSPLIKAPQQQQLPPQQQQQQQLVRSNSQQAAVIATAAALPAPATPTPPANLSSFASASGGMQVNVEKVQEHISKLISQNEAIVENKEILLQKKYPKQLNRSRSFNNANNSVNNNNNISSNISNATTITHANNNSSNSNQQLGETKVNLAQAIVQKQQQQQQQQQQHLQQQLQQQQQYQMYMQQQQQQQQQQLEPVNGLLKRSSSSSASSGYVSLKGTPTVTPTPTPNAKQQQQLPPPPSPLPPQQLQYRQDPATPVPKQELQPLAPNHAQPLNLSAKPKPAKPTAPPATATVVKSTPTAVQAAPNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICANEFRSADELKHHNSTYCQDASSSAPISPASSPGTKYFRSNSISFSLPELKSHMANSKNPLSLAKLAWSQLKTKPSSLVLSRLSASQSPARTSTVTNTSSSSSSSNHNNSNINHSNINNTNSNINNNNHNHSSNINNMPATVAVIPPSIDASSVALRFVDAPLPSPGPLLGKTALVDYAAPRKAPDAQVIITKMHEDRLENIINIETPTKRAKMSSDNAFALPHVQLLFAGQQELQYSAKEERLRRFTSSGGSMIPISECPELDKSPKMIRTPLLSGGSFQEMSPRLSDTNKERKLTAPNNGYLLSSAATPQHFQFPPINSITGFNPLTLPPMSNHSSNDAKSIPYVPGIPGPGSLSLLPPPQQLLPRGRSPNRKQPSPNPNPNPNLNPLLVTAEGPLKALSPFGGVQNLPSEFSRQPPTPAQRNALQWTSSSNKTPATVAAELSKKLPFNFLRMADNVKSQEQLQLQQQQQQEVRHFNFDNVNKTQEALAPLHVDTPDEPTTVATVATATATATATVTTSAIIITSSSAKSKFLRPTSLPLKPGTFTPKRHHGITPTENTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKPKQVMALYDSRQKMLGTGCSTSMAGTGKLHYSLVSSQQTVSTSSTTANVQSKFYQHQLKQPPSIGALSEANVAAKASEEAAAAEAKKLESGQLLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPADGEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRMKEHEAARGLLSLSMTPPIPQSVSPYPALAQDTPVPAASPANSIGSSGGSSQPKRQVCSFTSPKPPFDYQKQEQYYSNPEESKPKRAVPSDESSAPMDLTKPRSMPSSILFQLPEQTPPKSQAQQMRDVIFGAGNNECGFMKMLISVSDKVRISAEMEEQAKRESGDGEDVLLQTYIKEQALQHAKMKQSQFSRSYLATTTSSISSSCISSSCVRTPIVNSKPPLIITELPIIEVHEVKTPEPQSPVVPNVSKSAEESEESEADQEKPAIVAVPVSVSITETQPPHNANLPAAVQQPDATDFSGVLSSSSNNTSGSSATTAPTRTVIVGEEGFKGTPTTSTSNAAELQPGAAGTTPVYPGRVVAPPPPPIASDARPTCIICNKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHRNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLLEKDPNKLSGYTTPSGMLQLATEPPGVAGQDSASEDGFSAANSAAASAIASLDNDSAGNTPQRASSMSEDETLTNGLSHRHTLKRRLAGSSFSSNGDESDNPPEATVSGSEKRARSNTNELTLPVAGNTTTATATATASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00538457;
90% Identity
-
80% Identity
-