Basic Information

Insect: Drosophila flavopinicola
Gene Symbol: L
Assembly: GCA_035042425.1
Location: JAWNLL010000022.1:715052-724071[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.0007 19.9 2.9 1 23 166 188 166 188 0.98

2 17 0.39 24 5.6 6.2 1 23 194 216 194 216 0.97

3 17 1.9e-07 1.2e-05 25.5 3.2 1 23 222 244 222 244 0.99

4 17 1.4e-05 0.00086 19.6 0.4 1 23 250 272 250 272 0.99

5 17 0.051 3.2 8.4 0.1 2 23 345 370 344 370 0.94

6 17 0.0045 0.28 11.7 1.1 2 23 399 421 398 421 0.95

7 17 0.03 1.9 9.1 0.7 1 23 482 504 482 504 0.97

8 17 0.0057 0.36 11.4 0.1 2 23 512 533 511 533 0.91

9 17 0.0002 0.013 16.0 0.1 1 23 541 565 541 565 0.94

10 17 5.6 3.5e+02 2.0 1.7 2 23 601 623 600 623 0.95

11 17 0.0028 0.18 12.4 1.1 1 23 668 691 668 691 0.97

12 17 0.0071 0.44 11.1 1.6 2 23 866 888 865 888 0.96

13 17 0.13 7.9 7.2 0.1 1 23 894 916 894 916 0.92

14 17 1.5 96 3.8 1.2 2 23 924 945 923 945 0.93

15 17 1.1 67 4.2 0.5 2 23 1041 1062 1041 1062 0.94

16 17 0.057 3.5 8.3 0.0 1 23 1072 1094 1072 1094 0.94

17 17 0.0014 0.088 13.3 1.2 1 23 1099 1121 1099 1121 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.0007	19.9	2.9	1	23	166	188	166	188	0.98
2	17	0.39	24	5.6	6.2	1	23	194	216	194	216	0.97
3	17	1.9e-07	1.2e-05	25.5	3.2	1	23	222	244	222	244	0.99
4	17	1.4e-05	0.00086	19.6	0.4	1	23	250	272	250	272	0.99
5	17	0.051	3.2	8.4	0.1	2	23	345	370	344	370	0.94
6	17	0.0045	0.28	11.7	1.1	2	23	399	421	398	421	0.95
7	17	0.03	1.9	9.1	0.7	1	23	482	504	482	504	0.97
8	17	0.0057	0.36	11.4	0.1	2	23	512	533	511	533	0.91
9	17	0.0002	0.013	16.0	0.1	1	23	541	565	541	565	0.94
10	17	5.6	3.5e+02	2.0	1.7	2	23	601	623	600	623	0.95
11	17	0.0028	0.18	12.4	1.1	1	23	668	691	668	691	0.97
12	17	0.0071	0.44	11.1	1.6	2	23	866	888	865	888	0.96
13	17	0.13	7.9	7.2	0.1	1	23	894	916	894	916	0.92
14	17	1.5	96	3.8	1.2	2	23	924	945	923	945	0.93
15	17	1.1	67	4.2	0.5	2	23	1041	1062	1041	1062	0.94
16	17	0.057	3.5	8.3	0.0	1	23	1072	1094	1072	1094	0.94
17	17	0.0014	0.088	13.3	1.2	1	23	1099	1121	1099	1121	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTGgagaatttaattgaaaagatTCAGGCAACCAAGGAGATTACAAATAACGaTATGTACAGCACGCACACCTCGTCCAGCTACTCGCCCAGCATCTCGGATGGCACACTGACGCCCAACTCACAGCAGCAGACGGCAGCTGGGGGCAGCGAGGATGCCAGCAAGGAGCAGGCAAAGCCCAATGGCGAGGGTCctgccgagcagcagcagcaggagctggcgAAGCCGAAGCGCGCCGCCCAtttgcatcatcatcatcatcattatcatcatcagcaggCGCTGAAGCTTGCCAACAAGCTGCGCAAAATCAATAAGGAGAGCAagttggcagcggcagcaggagcagcaggagtgGCAGGACCTGGTGcagcaggcggcggcggcggcggcgtcggcgGCAAGTTTGATAAGTTGACAGGCGAGGGCATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTGCAGAGCCATGCTGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAACTGTTCAAACACAAACGCTCCCGAGATCGTCATAAGAAGCTGCATACGAATGAGAGGAACTACAAGTGTCCACATTGTGAGGCTGCTTTCTCCAGAAGCGATCATTTGAAGATTCACATGAAGACGCACGACATCCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGGGGCTATAATACCGCAGCTGCCCTCACCTCCCACATGCAGAAGCACAAGAAGAATGCAGCGATTCTGGCTGCCGGCGGTAATCCCAATGCATTGAACTATAGTCCACGCTCCACTGGCTCCGCATCCATATCGAGTAATGGCAGTTTGCACAAGCGTCGCTATGCTCTAGCTCTGGCCACCGACAGCAGTCCAAGTCGACTGGAGTTTCCCAAAAGGGCGCGTGGACACAATCCGAATGCGGCGACGCCAACGCCTCTGTTGCGTTGCAGCTACTGCAGTCCCAAGGTCACCGAGTTCAGCAGCCTGGAGCAGCTGAATGCGCATCTCCAGAGTGCACACGAACAGCAACCGCAGTTGGGAGTGAGAAGTGCCACAGCGACCACAGAGGCAGTGGAGCCGGCCCAGGCGAATGGCTTTCAGCTGAGCTGCGAATATTGCACCATGAAGTTCCACAATATTGCTGCACTCTTCCAACACATGCGTGCCACGCACTTGGATCGTTTGAGCAGTCCCAACTCCTACTATGAGCACTTCAATCGACTGGCCACAGCGGGCACATTCAGTCCGCCCAAGATCAAGCAGGACTTGGCCAGTCCTCCGGCGCCCGAGGAGCTGCCAACGGATTTGAGCAGCAAGCAGCGTAGAACGCTGACGCCAGCGCCACCTGGCGTCTTCTTTTGCAACCAGTGCAATGCAGGTCTGCCGGACTTCGAAAGCTTTCGCAATCATCTGAAGACGCACATAGCCGAAGGCATGCAGCTGATTTGTCCACATTGCGGCTTGAGTCTGCCGGAGCAGAGTGAATTCGAGCGTCATGTGGTGGCTCACTTTCTGATCAGCAGCTCGGAGTTCAATTGCAGCGGCAGCTGTGGCAAATCCTTTGCCAAGgcggaggagctgcagcagcatctgaTCAGTGAACATGTGCAGACGCTGCTCAAGTGCATCATCTGCTCGGAGCTGTGCGAGAACAGGATGTCCATGCAGCTCCATTTGGCCTGTGCGCACAGTCAGGAGACGAAGCTGCTCCGATGCAGCGCCTGCTTGGAACTCTTTCGCACCGATACCGACTTCCATGTGCATGTGAAGACGCGTCATCAGCTGACAACTGGTGGGGGAGGTGgccctcctcctgctgctcctgccaaTCCCTTGCAGTGCATGTTCTGTCGCGCTGTTTGTGCCTCGGAGCTGGAGATGCATTTCCATTTGGCGGCACATGCGAGACAATTCCGCTGTCCCAGCTGCCCGGAAACGTTCCACGTGGAGTTCCTGCTCGATCGCCATATGCAGAGCCAGCATGGCGGCGTCAAGGATAAGGAGCCCACTTCCAATTCCATGGGCAGTCTCTATGTGAACGCCTTGTTGCCACCtttggcggcagcagcggctgcggctgcggcagcAACGAATAACAACAGTAATCTGCATATTGATTACAATGTGGCGTTTAAGGGCCTGTTTggaggaggcggcggcggaggcggaaatgccacgcccactaatgcacagccagccagcaagttCTACAGTCCGTTGCAGGTGGACACGAGTGCACTGAAGCCCCAACAGACGCCCCATCCGGCGCTGATGTACGGCCTGAGTCAGCGCTATCTGATGGAGATGTACGCTGCCAAGGCGACCTCGCCGGCGGCCAGTGCACCCGAGCTGCcggcccaagcccaagcccaagcgaATGCGACAGCTTCCAGTGCCGGGAGCAGCTACAGCTGTGGCATGTGCGAGCGGCAGGATTTGCGCAGCGAGGCGGAGCTGCACTCGCATCGCAAGCTGGCGCACAATCTGAAGACGGGGGTTAGCTTGAGATGTGCCTACTGCTCGGGCAACTACAAGTCGCGGgcggagctggagcagcacaTGAAGAGCTGTCACAATTCCAGCGGCAAGCACAAGTGTCTCATTTGCGATGAGATCTTCCCATCGCCAGCCATCCTCGCCGAGCACAAGCTGCAGCACTCCAAGGTGGGGCAGTCGGGCAAGTGTGCCCACTGTGGCCACCAGCTGGAGCACGTGGCCGCCTTCCGTGCCCATCTGGGCGAGCATGGCAACGATGGCAATTTGCCCATGGCCTGCATTTGCTGTCGGCAAACATTGCACTCGGAATTCGAGCTGAGTCTGCATGCCAAATTCCATACGAAGTCACCCAGTTGTGGTAGTCTGCAGGAGCCAGTTTGTGCTTTGTGCCTGGAACCGTTGCCCGGATCGGGTGAAACGGCCAAGTTGTGTGACAAGTGCTGTCGCAAACacaatttgaatggcaaacgCAGCAAGGAGGCGCCGCCAGCGATTGCTCCTTCGGCAGCAAGTGGAGCTGCCTATCTGGAGAATCGCTGTAATCTGTGCAAGCTGATATTGCCACATGCTCAGAAGCTGCAGGAGCATCTGGTGGAGCACACTTTCGCTGGCACCGAGCAGCGTGGCTTCAATTGCTACATTTGCTCGGCGGTCTTTACAGCGCCCGCAGGACTCTTGGCCCACATTGGGGAGCACGGTGCTCGTCCTTACGACTGCAATCTGTGCCCGGAGAAGTTCTACTTTCGCGCCGAACTGGATCATCATCAGCGCGCCCATGAGCTGAGGCCAGTAGCCGTCACGCCTGCTCCAAGATCGCAGCCCAAACAGGAGGCGCTCAGCTCCTCGGCCAGTTCACCCATTGCGCTCAGTCCTCAGACTCATGTCAAGCAGGAGCTGTACGAATCTGAAACGCCGCCCTCACCGCAACAGCcggaggcgcctgtccaggaggaggaggagtacaTCGAGGTGGAGCAGGTGCCGCTGGAGACGCGCTCCAATGAGCTCTTGTCCAACTCGCACACCGAacgctccagcagcagcgcctga
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQQQTAAGGSEDASKEQAKPNGEGPAEQQQQELAKPKRAAHLHHHHHHYHHQQALKLANKLRKINKESKLAAAAGAAGVAGPGAAGGGGGGVGGKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALATDSSPSRLEFPKRARGHNPNAATPTPLLRCSYCSPKVTEFSSLEQLNAHLQSAHEQQPQLGVRSATATTEAVEPAQANGFQLSCEYCTMKFHNIAALFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPPKIKQDLASPPAPEELPTDLSSKQRRTLTPAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLISSSEFNCSGSCGKSFAKAEELQQHLISEHVQTLLKCIICSELCENRMSMQLHLACAHSQETKLLRCSACLELFRTDTDFHVHVKTRHQLTTGGGGGPPPAAPANPLQCMFCRAVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDKEPTSNSMGSLYVNALLPPLAAAAAAAAAATNNNSNLHIDYNVAFKGLFGGGGGGGGNATPTNAQPASKFYSPLQVDTSALKPQQTPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAQAQAQANATASSAGSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGHQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCGSLQEPVCALCLEPLPGSGETAKLCDKCCRKHNLNGKRSKEAPPAIAPSAASGAAYLENRCNLCKLILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLAHIGEHGARPYDCNLCPEKFYFRAELDHHQRAHELRPVAVTPAPRSQPKQEALSSSASSPIALSPQTHVKQELYESETPPSPQQPEAPVQEEEEYIEVEQVPLETRSNELLSNSHTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: -
80% Identity: -