Dfla010902.1
Basic Information
- Insect
- Drosophila flavopinicola
- Gene Symbol
- -
- Assembly
- GCA_035042425.1
- Location
- JAWNLL010000452.1:498573-501173[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.082 5.1 7.8 5.9 3 23 268 288 266 288 0.96 2 12 0.013 0.79 10.3 0.4 1 23 294 319 294 319 0.92 3 12 0.004 0.25 11.9 1.1 1 23 326 351 326 351 0.95 4 12 0.00086 0.054 14.0 2.1 1 23 363 385 363 385 0.98 5 12 2.8e-06 0.00017 21.8 0.2 1 23 392 414 392 414 0.98 6 12 0.008 0.5 11.0 0.1 1 23 420 442 420 442 0.98 7 12 0.0077 0.48 11.0 4.0 1 23 448 471 448 471 0.98 8 12 0.011 0.66 10.6 3.9 1 23 477 499 477 499 0.96 9 12 0.00018 0.011 16.1 3.6 2 23 506 527 505 527 0.96 10 12 4.7e-05 0.0029 18.0 0.3 1 23 639 662 639 662 0.96 11 12 0.012 0.77 10.3 1.2 1 19 668 686 668 690 0.94 12 12 2e-06 0.00013 22.2 4.1 1 23 696 718 696 718 0.99
Sequence Information
- Coding Sequence
- ATGAGTGAGAGGAGGGGATACTCCATACACACAATATGCCGCATCTGCCTGAATCATTTGCAAAACGATCCGGCCTACGATCTGTTCCTGGTCCCGGGCCTGGCCAAGAAGCTATGTGTGTGCACCTCACTCTCCGTGGAGCAGCACGACGGCTTCCCAATGAATCTGTGCACCAATTGCTACACGCGGCTAAGCGACATGCACGACTTCCAGAAGCTGTGCGTGGACTCCGTACAACGGTTTCACGACATGGTCGCCAGCAACTTCTTCACAGCAAGCGCCGCACAACACATGAATCAAATCGACAACTTTGATGTGCTGAATGTGGCGACACAGGATGCCGATTTGGGTGGCGAGGAGGATGATCGCATTAACTATGATCCGCTGCTCAATCACAAGATGGAGATAATCGAGAACGAGGAAGATGTGTTCAAAATGCTCGAGCACGTCGATAAAGAGGCTGAGGAGGCGGAGAAGGATGTCAAACAGGATGTGGATGACGTGTCGGGTATTATACAAATGTTTGGCGACGAGTCCTCCATCGAGAGCAGCAACGAGAACGACAATGACATGGACTTTGAGCCCAACAGCACCGACGGTGACGACGACATGCCTTTGGCGCAACGTCTGCGCGGCAATCCCCGAAtgacaggcagcagcaaaacaagtgCACGCAAAGCTTCAGCAAGCGCCGAGCTTGAGGATGACTACAGCTCAGCATCGGATGAGGACGGCGCCAAGTCGAGGCTAAAACGCAAACGGATTCCGGCTGCTGAGCGGCACTTGCATCGCATTATTGACTGTCACATCTGCCATCAGAAGTTCAAGAAGGCGATTCGCTACGAGGAGCACATGAAGCATCACAATGATCTGTTGCCCTTCCAGTGTAAAGTGGAGAGCTGCCGCAAGGGCTTCACCACTGCCGGTGGGCTGAGGCTGCATGTGGATCATGCGCACACGGAACTGTCCGAGGTGCATTCGTGCAGTGTGGAAGGATGCGGCAAGACATTCCCGCGCATTCGCCTGCTCACCTTCCACATGAAAAAGGTGCACAACATCTCGAAGGCGGCGGCGCCGCCCAGGGACTATCCGTGCACGGAGTGCGAGAAGATTTTCCGCTGTCCCATGGCTCTGAAAAAGCACATGTACAAGCACGACGGCAAGGAGCTGCCCTTCCCATGCAACATATGCGGCAAACGGTTCGTGATCAACAGCGCGCTCAAGGATCATCTGATGCGGCATGCGGGCATCAAGAACTACGTGTGTCCGTACTGTGGTGTTGGGAAAACGACGCGCCAGGAGTGGAACACACACATCCTGACGCACACGCAGGAGAAGAAATTTAAGTGCCACATCTGCGAGCATGCCTCGCATAACAAGCAGAGTCTGGCGAACCACATTAAAATCGTGCACGAAAAGATTAAGAACTATGCGTGCCAGTACTGTGGGAAGACCTTTGGTAAATCGCACGCCTGCAAGATTCATGAGATGACGCACACCGGCGAGAAGCGATGCGAGTGCAAGGTGTGCGGCAAGAAATTCCTCTATCCCAAGAGCCTCACGAAGCATCTGAAGACGCACGAGAAGCGTGTTCTGCGCGCCATTGAAACGTATCGCCAGCGGCAGGTGGAACTGGGAGAGGGGGCGACGGGCAGCGGCGAACCAACGGCGGATATGGCGtcagcgactgcagcagccacCAGCACAGATGCTGCCGATGTTCACGTGTCACAAAATGCCGCCGATGAACTGCTCAAGGTGTGCGCCGAGTCGGTGGCCACAATACCCAGAGATCCACGCCGGGTGCAGCGTGTGGACATTGCCCAGCTGGCTGGCACCGCCGTCAATCCGATACCGTCCGTGTCCGTGCCCTCCTGGTCGCCCCAGGTGAACTTCACAAAGAAGGAAGGCAAACACATCTGCCCCGGCTGCGGGCAGGGCTTTAATAACATTGGCAACATGAAGCGTCACTATAAGATTATACACGAGAAGGTCAAGGATTTTGCGTGTCGTTTCTGTCCCAAGCGCTTTGCCAAGGCGCAGACCCTGCGCCATCACGAATGGATACACACCGGCGAGAAGCCGTTCGAGTGCAAGACCTGCGGAACACATTTCCGCCAGGAGACGGCGCTCAAGCGGCATCAGCGCACGCACGAGAACCGCCCGCCCGTCATCTCGTCCAAGTTCTATGCGGCACGCGAGGAGCTCGAGGAGCAGGAGCGCACTAAACGCGAGGCCCGCCGCAAGGCCGACGCGAAGCGCAAGGAAATCGCGGAGGCGGCCAAAGAGCAACTGTCGTCACTGCACAAGATCGAGGCGACCGACAAGAATCTGCACTCGTACGATGAGTACCAGGAGGCGGCGGCAGAGCGTGCAGCGGCTTCCGCTGAACTGCAGGCACAGCAGTTCGAGGAGAACGAGGTAAAGCGGCTGGCGGACATGGAACGTCGCAAGATACAGGAGGCCGCCtacgagcagctgcagcggctgcagcagcagcaggaaatcGAAAAGGCGCAGAGCTCCTACGACGGCTACTATGCACAAAAGGCGACCGCTGAAGGCAGCACCATCGATGAATTAAGGATCGATCATGTCTGA
- Protein Sequence
- MSERRGYSIHTICRICLNHLQNDPAYDLFLVPGLAKKLCVCTSLSVEQHDGFPMNLCTNCYTRLSDMHDFQKLCVDSVQRFHDMVASNFFTASAAQHMNQIDNFDVLNVATQDADLGGEEDDRINYDPLLNHKMEIIENEEDVFKMLEHVDKEAEEAEKDVKQDVDDVSGIIQMFGDESSIESSNENDNDMDFEPNSTDGDDDMPLAQRLRGNPRMTGSSKTSARKASASAELEDDYSSASDEDGAKSRLKRKRIPAAERHLHRIIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCKVESCRKGFTTAGGLRLHVDHAHTELSEVHSCSVEGCGKTFPRIRLLTFHMKKVHNISKAAAPPRDYPCTECEKIFRCPMALKKHMYKHDGKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHILTHTQEKKFKCHICEHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYPKSLTKHLKTHEKRVLRAIETYRQRQVELGEGATGSGEPTADMASATAAATSTDAADVHVSQNAADELLKVCAESVATIPRDPRRVQRVDIAQLAGTAVNPIPSVSVPSWSPQVNFTKKEGKHICPGCGQGFNNIGNMKRHYKIIHEKVKDFACRFCPKRFAKAQTLRHHEWIHTGEKPFECKTCGTHFRQETALKRHQRTHENRPPVISSKFYAAREELEEQERTKREARRKADAKRKEIAEAAKEQLSSLHKIEATDKNLHSYDEYQEAAAERAAASAELQAQQFEENEVKRLADMERRKIQEAAYEQLQRLQQQQEIEKAQSSYDGYYAQKATAEGSTIDELRIDHV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00575777;
- 90% Identity
- iTF_00546820;
- 80% Identity
- -