Basic Information

Insect: Drosophila flavopinicola
Gene Symbol: ZNF526
Assembly: GCA_035042425.1
Location: JAWNLL010000337.1:210872-213410[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.13 8.3 7.1 0.3 1 21 306 326 306 327 0.95

2 10 2.3e-06 0.00015 22.1 1.8 1 23 335 357 335 357 0.99

3 10 0.018 1.1 9.9 1.1 1 23 360 383 360 383 0.92

4 10 1.4e-06 8.7e-05 22.8 0.8 2 23 390 411 389 411 0.98

5 10 1.6e-07 9.8e-06 25.8 0.7 1 23 417 439 417 439 0.98

6 10 8.8e-06 0.00055 20.3 1.9 1 23 445 467 445 467 0.99

7 10 0.00044 0.028 14.9 4.6 1 23 473 495 473 495 0.99

8 10 0.0011 0.069 13.7 0.3 1 23 501 523 501 523 0.98

9 10 0.00012 0.0076 16.7 3.7 1 23 529 551 529 551 0.98

10 10 0.00052 0.033 14.7 0.3 1 23 557 579 557 579 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.13	8.3	7.1	0.3	1	21	306	326	306	327	0.95
2	10	2.3e-06	0.00015	22.1	1.8	1	23	335	357	335	357	0.99
3	10	0.018	1.1	9.9	1.1	1	23	360	383	360	383	0.92
4	10	1.4e-06	8.7e-05	22.8	0.8	2	23	390	411	389	411	0.98
5	10	1.6e-07	9.8e-06	25.8	0.7	1	23	417	439	417	439	0.98
6	10	8.8e-06	0.00055	20.3	1.9	1	23	445	467	445	467	0.99
7	10	0.00044	0.028	14.9	4.6	1	23	473	495	473	495	0.99
8	10	0.0011	0.069	13.7	0.3	1	23	501	523	501	523	0.98
9	10	0.00012	0.0076	16.7	3.7	1	23	529	551	529	551	0.98
10	10	0.00052	0.033	14.7	0.3	1	23	557	579	557	579	0.97

Sequence Information

Coding Sequence: ATGGATGTGGAGAAGATTTGTCGCACCTGTTTAAGCCTCTCGGGGCCTTTTCTATCCATCTACGATGGCGGCTCAGGTAGCTGTCTGGTCGATATGCTGCGCGAGTTTACAAGGACCAAGCCGCGTCATGAGGATAATTTGCCAGGCAGGGTTTGCCTGAGCTGCATCAGTGAAATAAATCACTGCTACTCGTTCAAACTGAAATGCGAAAGCTCGAATCGCACATTGCGACAGCTGCTGCCCAATGCGCTGCCCGAGGAGCCCCTATCTGGGACAAAGCCGTCTGTGGCCACTTCGGAGAAATGCATGCAAACCAGCGAAGTAACAACAGTCACAACGGAGGCGCAAACGGATGAGGTGACAACAGCAGATGCTGCTCAAAATACCAGCCtggagcagccagcagcgacgCTGGCCGAAGAGCCCCAGGAGCACGAGGAGGACGAGGAAGAGGAGCAAGAGTTTGACTATGAATTTACCGAAGAGCAGGAAAACGATGAAGCGCCATCCAAAGCTGGTGCTGAGAATATCATACTGCATGTGGAAAAGGACAATGTAAAGTACGAAACGGAAATGCTGTACAACAAGAACACGGGCGAGTTGCTCGAACAGCCGCTCGAAGCCGTTGCCAAGCAGAAGGAATACAAATATCGACTGGTCAGCAATGGTAACGGCGACACATTCATTTCCCCAGAGACAGCGCCCAAAAGCGTCACAAAGCCGCCGCAAGCGGATGCAGTAGAGGAACTTATCTCGCCGGATCGACCGGTCTCACGCTCCATGTCCAAGCGACgtcgcgctgctgctgcctcgcaGCTGGCGGAGCAGGCCGAAGCAGCGCCCGTTAAGAAACCAAAAATGAATCAGAACCTGAATGGTTCGCCTGCAGCTGAAGTGGAGGAGCTGAAGGCCAATTTCCACTGCGATCGCTGCAATGCGGGCTTTGCCCTGGAGAAGTCCCTGATCATTCACAGGCGGCAAAATGGTTGCACCCACCGCAACTTCAAGTGCAACGAATGCGAGCGGGTTTTCGTCTCGCTAGATCACCTGACGGAGCATCAGACCACACATGGCGCGCACAGCTGTCAGGAGTGCGGCCTGCCCTGCGAGTCCATGGAGCAGCTGGGCAGGCACATGGTGCAGACGCACAAGCGCAATCTTCGCAATCAGTGCAACGTTTGCCAGAAGGTATTCACAATGCTGTCAACTCTGCGGGATCACATGCGCATCCACACCGGCGAGAAGCCATTCGTATGCAACGTCTGCGGCAAGGGCTTCACACAGAACGCAAATTTGCGACAGCACAAGATGCGCCACTCGGACATCAAGCGCTTCAAGTGCGAGCTGTGCAGCCATTCGTTTGTGACCAAAGCGGAGCTCACCTCGCACGCACGCACCCATACGGGCGTTAAGCCGTATCAGTGTGAAGTGTGCTCATCCCGATTCACCACCAGCTGCTCACTGGCTAAGCACAAGCGGAAACACACAGGCGAACGGCCCTACGCCTGTGATCTGTGTCCCATGCGTTTCACGGCGCTCAATGTGCTGAAGAATCACCGCAGAACGCACACGGGCGAGCGGCCATTCGTGTGTCCTTTCTGCTCCAAGAGCTTCACGCAGCGCGGCGACTGCCAAATGCATCAGCGCACCCATCAGGGCGACAAGATCTACATTTGCCCCGTTTGCAGTGAGGAGTTCAAGACGATGAACGATATGCGAACACATCTAACGATGCACGAACAGGACGACAAGCGACTGGTGCACTTCACCCTGTTGAGCAACAAAGAGAATGGCAGCGGGACTCTGGAAGAGGCCGATGAGGAGTCGGATGCAACTGATTTGCTGTAG
Protein Sequence: MDVEKICRTCLSLSGPFLSIYDGGSGSCLVDMLREFTRTKPRHEDNLPGRVCLSCISEINHCYSFKLKCESSNRTLRQLLPNALPEEPLSGTKPSVATSEKCMQTSEVTTVTTEAQTDEVTTADAAQNTSLEQPAATLAEEPQEHEEDEEEEQEFDYEFTEEQENDEAPSKAGAENIILHVEKDNVKYETEMLYNKNTGELLEQPLEAVAKQKEYKYRLVSNGNGDTFISPETAPKSVTKPPQADAVEELISPDRPVSRSMSKRRRAAAASQLAEQAEAAPVKKPKMNQNLNGSPAAEVEELKANFHCDRCNAGFALEKSLIIHRRQNGCTHRNFKCNECERVFVSLDHLTEHQTTHGAHSCQECGLPCESMEQLGRHMVQTHKRNLRNQCNVCQKVFTMLSTLRDHMRIHTGEKPFVCNVCGKGFTQNANLRQHKMRHSDIKRFKCELCSHSFVTKAELTSHARTHTGVKPYQCEVCSSRFTTSCSLAKHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPFVCPFCSKSFTQRGDCQMHQRTHQGDKIYICPVCSEEFKTMNDMRTHLTMHEQDDKRLVHFTLLSNKENGSGTLEEADEESDATDLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00551023;
90% Identity: -
80% Identity: -